Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	K	T	F	L	V	E	I	G	T	E	E	L	P	P	K	A	L	R	S	L	A	E	S	F	A	A	N	F	T	A	E	L	D	N	A	G	L	A	H	G	T	V	Q	W	F	A	A	P	R	R	L	A	L	K	V	A	N
Secondary structure
SS confidence
Disorder		?	?	?	?																																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	A	E	A	Q	P	D	R	E	I	E	K	R	G	P	A	I	A	Q	A	F	D	A	E	G	K	P	S	K	A	A	E	G	W	A	R	G	C	G	I	T	V	D	Q	A	E	R	L	T	T	D	K	G	E	W	L	L	Y	R	A
Secondary structure
SS confidence
Disorder				?		?	?	?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	V	K	G	E	S	T	E	A	L	L	P	N	M	V	A	T	S	L	A	K	L	P	I	P	K	L	M	R	W	G	A	S	D	V	H	F	V	R	P	V	H	T	V	T	L	L	L	G	D	K	V	I	P	A	T	I	L	G	I
Secondary structure
SS confidence
Disorder																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	S	D	R	V	I	R	G	H	R	F	M	G	E	P	E	F	T	I	D	N	A	D	Q	Y	P	E	I	L	R	E	R	G	K	V	I	A	D	Y	E	E	R	K	A	K	I	K	A	D	A	E	E	A	A	R	K	I	G	G	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	D	L	S	E	S	L	L	E	E	V	A	S	L	V	E	W	P	V	V	L	T	A	K	F	E	E	K	F	L	A	V	P	A	E	A	L	V	Y	T	M	K	G	D	Q	K	Y	F	P	V	Y	A	N	D	G	K	L	L	P	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		F	I	F	V	A	N	I	E	S	K	D	P	Q	Q	I	I	S	G	N	E	K	V	V	R	P	R	L	A	D	A	E	F	F	F	N	T	D	R	K	K	R	L	E	D	N	L	P	R	L	Q	T	V	L	F	Q	Q	Q	L	G	T
Secondary structure
SS confidence
Disorder												?																																							?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	R	D	K	T	D	R	I	Q	A	L	A	G	W	I	A	E	Q	I	G	A	D	V	N	H	A	T	R	A	G	L	L	S	K	C	D	L	M	T	N	M	V	F	E	F	T	D	T	Q	G	V	M	G	M	H	Y	A	R	H	D
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	E	A	E	D	V	A	V	A	L	N	E	Q	Y	Q	P	R	F	A	G	D	D	L	P	S	N	P	V	A	C	A	L	A	I	A	D	K	M	D	T	L	A	G	I	F	G	I	G	Q	H	P	K	G	D	K	D	P	F	A	L
Secondary structure
SS confidence
Disorder																		?		?	?		?	?	?	?																						?	?						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		R	R	A	A	L	G	V	L	R	I	I	V	E	K	N	L	N	L	D	L	Q	T	L	T	E	E	A	V	R	L	Y	G	D	K	L	T	N	A	N	V	V	D	D	V	I	D	F	M	L	G	R	F	R	A	W	Y	Q	D	E	G
Secondary structure
SS confidence
Disorder																																	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		Y	T	V	D	T	I	Q	A	V	L	A	R	R	P	T	R	P	A	D	F	D	A	R	M	K	A	V	S	H	F	R	T	L	D	A	A	A	A	L	A	A	A	N	K	R	V	S	N	I	L	A	K	S	D	E	V	L	S	D	R
Secondary structure
SS confidence
Disorder																																																				?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		V	N	A	S	T	L	K	E	P	E	E	I	K	L	A	M	Q	V	V	V	L	R	D	K	L	E	P	Y	F	T	E	G	R	Y	Q	D	A	L	V	E	L	A	E	L	R	E	P	V	D	A	F	F	D	K	V	M	V	M	V	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.
Sequence		D	K	E	L	R	I	N	R	L	T	M	L	E	K	L	R	E	L	F	L	R	V	A	D	I	S	L	L	Q
Secondary structure
SS confidence
Disorder																									?			?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1f7u chain A domain 1 Region: 574 - 685 Aligned: 112 Modelled: 112 Confidence: 99.4% Identity: 20% Fold: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Superfamily: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Family: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Phyre2 PDB 1f7u chain A Region: 572 - 681 Aligned: 110 Modelled: 110 Confidence: 98.4% Identity: 20% PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of the arginyl-trna synthetase complexed with the2 trna(arg) and l-arg Phyre2 PDB 2zuf chain A Region: 572 - 685 Aligned: 114 Modelled: 114 Confidence: 98.0% Identity: 17% PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii arginyl-trna2 synthetase complexed with trna(arg) Phyre2 PDB 1iq0 chain A Region: 498 - 685 Aligned: 166 Modelled: 169 Confidence: 97.9% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: thermus thermophilus arginyl-trna synthetase Phyre2 PDB 3gw7 chain A Region: 365 - 556 Aligned: 162 Modelled: 171 Confidence: 97.9% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein yedj; PDBTitle: crystal structure of a metal-dependent phosphohydrolase2 with conserved hd domain (yedj) from escherichia coli in3 complex with nickel ions. northeast structural genomics4 consortium target er63 Phyre2 PDB 1iq0 chain A domain 1 Region: 574 - 685 Aligned: 109 Modelled: 112 Confidence: 97.6% Identity: 19% Fold: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Superfamily: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Family: Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Phyre2 PDB 2o08 chain B Region: 362 - 459 Aligned: 93 Modelled: 98 Confidence: 97.5% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:bh1327 protein; PDBTitle: crystal structure of a putative hd superfamily hydrolase (bh1327) from2 bacillus halodurans at 1.90 a resolution Phyre2 PDB 2pq7 chain A domain 1 Region: 355 - 493 Aligned: 129 Modelled: 139 Confidence: 97.3% Identity: 20% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2pjq chain A domain 1 Region: 362 - 538 Aligned: 149 Modelled: 156 Confidence: 97.3% Identity: 16% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2qgs chain A domain 1 Region: 362 - 542 Aligned: 154 Modelled: 160 Confidence: 97.2% Identity: 14% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 3ccg chain A Region: 362 - 459 Aligned: 93 Modelled: 98 Confidence: 97.2% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:hd superfamily hydrolase; PDBTitle: crystal structure of predicted hd superfamily hydrolase involved in2 nad metabolism (np_347894.1) from clostridium acetobutylicum at 1.503 a resolution Phyre2 PDB 3fnr chain A Region: 572 - 685 Aligned: 112 Modelled: 114 Confidence: 97.2% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of putative arginyl t-rna synthetase from2 campylobacter jejuni; Phyre2 PDB 2ogi chain A Region: 362 - 459 Aligned: 93 Modelled: 98 Confidence: 96.8% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein sag1661; PDBTitle: crystal structure of a putative metal dependent phosphohydrolase2 (sag1661) from streptococcus agalactiae serogroup v at 1.85 a3 resolution Phyre2 PDB 1r89 chain A domain 3 Region: 3 - 142 Aligned: 124 Modelled: 140 Confidence: 96.7% Identity: 12% Fold: Ferredoxin-like Superfamily: PAP/Archaeal CCA-adding enzyme, C-terminal domain Family: Archaeal tRNA CCA-adding enzyme Phyre2 PDB 3djb chain A domain 1 Region: 362 - 461 Aligned: 88 Modelled: 100 Confidence: 96.3% Identity: 16% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 3hc1 chain A Region: 361 - 513 Aligned: 149 Modelled: 153 Confidence: 95.9% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized hdod domain protein; PDBTitle: crystal structure of hdod domain protein with unknown function2 (np_953345.1) from geobacter sulfurreducens at 1.90 a resolution Phyre2 PDB 3m1t chain A Region: 361 - 513 Aligned: 136 Modelled: 153 Confidence: 95.8% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:putative phosphohydrolase; PDBTitle: crystal structure of putative phosphohydrolase (yp_929327.1) from2 shewanella amazonensis sb2b at 1.62 a resolution Phyre2 PDB 2x1l chain C Region: 532 - 685 Aligned: 149 Modelled: 154 Confidence: 95.6% Identity: 16% PDB header:ligase Chain: C: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of mycobacterium smegmatis methionyl-trna2 synthetase in complex with methionine and adenosine Phyre2 PDB 3dto chain A domain 1 Region: 343 - 461 Aligned: 103 Modelled: 119 Confidence: 95.6% Identity: 17% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 1sz1 chain A Region: 3 - 142 Aligned: 124 Modelled: 140 Confidence: 94.4% Identity: 13% PDB header:transferase/rna Chain: A: PDB Molecule:trna nucleotidyltransferase; PDBTitle: mechanism of cca-adding enzymes specificity revealed by crystal2 structures of ternary complexes Phyre2 1 d1f7ua1 2 c1f7uA_ 3 c2zufA_ 4 c1iq0A_ 5 c3gw7A_ 6 d1iq0a1 7 c2o08B_ 8 d2pq7a1 9 d2pjqa1 10 d2qgsa1 11 c3ccgA_ 12 c3fnrA_ 13 c2ogiA_ 14 d1r89a3 15 d3djba1 16 c3hc1A_ 17 c3m1tA_ 18 c2x1lC_ 19 d3dtoa1 20 c1sz1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99