Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	L	K	T	T	L	F	G	N	V	Y	Q	F	K	D	V	K	E	V	L	A	K	A	N	E	L	R	S	G	D	V	L	A	G	V	A	A	A	S	S	Q	E	R	V	A	A	K	Q	V	L	S	E	M	T	V	A	D	I	R
Secondary structure
SS confidence
Disorder		?	?	?				?			?													?	?	?	?	?	?	?	?										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	N	P	V	I	A	Y	E	D	D	C	V	T	R	L	I	Q	D	D	V	N	E	T	A	Y	N	Q	I	K	N	W	S	I	S	E	L	R	E	Y	V	L	S	D	E	T	S	V	D	D	I	A	F	T	R	K	G	L	T	S	E
Secondary structure
SS confidence
Disorder																																														?									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	V	A	A	V	A	K	I	C	S	N	A	D	L	I	Y	G	A	K	K	M	P	V	I	K	K	A	N	T	T	I	G	I	P	G	T	F	S	A	R	L	Q	P	N	D	T	R	D	D	V	Q	S	I	A	A	Q	I	Y	E	G
Secondary structure
SS confidence
Disorder																				?		?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?					?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	S	F	G	V	G	D	A	V	I	G	V	N	P	V	T	D	D	V	E	N	L	S	R	V	L	D	T	I	Y	G	V	I	D	K	F	N	I	P	T	Q	G	C	V	L	A	H	V	T	T	Q	I	E	A	I	R	R	G	A	P
Secondary structure
SS confidence
Disorder																		?																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	G	L	I	F	Q	S	I	C	G	S	E	K	G	L	K	E	F	G	V	E	L	A	M	L	D	E	A	R	A	V	G	A	E	F	N	R	I	A	G	E	N	C	L	Y	F	E	T	G	Q	G	S	A	L	S	A	G	A	N	F
Secondary structure
SS confidence
Disorder														?																						?	?	?																?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	A	D	Q	V	T	M	E	A	R	N	Y	G	L	A	R	H	Y	D	P	F	I	V	N	T	V	V	G	F	I	G	P	E	Y	L	Y	N	D	R	Q	I	I	R	A	G	L	E	D	H	F	M	G	K	L	S	G	I	S	M	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		C	D	C	C	Y	T	N	H	A	D	A	D	Q	N	L	N	E	N	L	M	I	L	L	A	T	A	G	C	N	Y	I	M	G	M	P	L	G	D	D	I	M	L	N	Y	Q	T	T	A	F	H	D	T	A	T	V	R	Q	L	L	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.
Sequence		L	R	P	S	P	E	F	E	R	W	L	E	S	M	G	I	M	A	N	G	R	L	T	K	R	A	G	D	P	S	L	F	F
Secondary structure
SS confidence
Disorder																		?	?				?											?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3abq chain A Region: 1 - 453 Aligned: 453 Modelled: 453 Confidence: 100.0% Identity: 100% PDB header:lyase Chain: A: PDB Molecule:ethanolamine ammonia-lyase heavy chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with cn-cbl and 2-amino-1-propanol Phyre2 PDB 2qez chain C Region: 3 - 453 Aligned: 435 Modelled: 449 Confidence: 100.0% Identity: 60% PDB header:lyase Chain: C: PDB Molecule:ethanolamine ammonia-lyase heavy chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase heavy chain2 (yp_013784.1) from listeria monocytogenes 4b f2365 at 2.15 a3 resolution Phyre2 PDB 1eex chain A Region: 66 - 431 Aligned: 327 Modelled: 340 Confidence: 94.6% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Cobalamin (vitamin B12)-dependent enzymes Family: Diol dehydratase, alpha subunit Phyre2 PDB 1iwp chain A Region: 66 - 317 Aligned: 230 Modelled: 252 Confidence: 93.9% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Cobalamin (vitamin B12)-dependent enzymes Family: Diol dehydratase, alpha subunit Phyre2 PDB 3bww chain A Region: 291 - 394 Aligned: 102 Modelled: 104 Confidence: 53.4% Identity: 16% PDB header:metal binding protein Chain: A: PDB Molecule:protein of unknown function duf692/cog3220; PDBTitle: crystal structure of a duf692 family protein (hs_1138) from2 haemophilus somnus 129pt at 2.20 a resolution Phyre2 PDB 3bq7 chain A Region: 86 - 134 Aligned: 45 Modelled: 49 Confidence: 51.1% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:diacylglycerol kinase delta; PDBTitle: sam domain of diacylglycerol kinase delta1 (e35g) Phyre2 PDB 2fpg chain A Region: 181 - 284 Aligned: 91 Modelled: 104 Confidence: 43.0% Identity: 22% PDB header:ligase Chain: A: PDB Molecule:succinyl-coa ligase [gdp-forming] alpha-chain, PDBTitle: crystal structure of pig gtp-specific succinyl-coa2 synthetase in complex with gdp Phyre2 PDB 1v85 chain A Region: 80 - 100 Aligned: 21 Modelled: 21 Confidence: 39.8% Identity: 10% PDB header:apoptosis Chain: A: PDB Molecule:similar to ring finger protein 36; PDBTitle: sterile alpha motif (sam) domain of mouse bifunctional2 apoptosis regulator Phyre2 PDB 2nu8 chain D Region: 181 - 284 Aligned: 92 Modelled: 104 Confidence: 37.2% Identity: 21% PDB header:ligase Chain: D: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha; PDBTitle: c123at mutant of e. coli succinyl-coa synthetase Phyre2 PDB 3qml chain C Region: 409 - 431 Aligned: 23 Modelled: 23 Confidence: 35.9% Identity: 17% PDB header:chaperone/protein transport Chain: C: PDB Molecule:nucleotide exchange factor sil1; PDBTitle: the structural analysis of sil1-bip complex reveals the mechanism for2 sil1 to function as a novel nucleotide exchange factor Phyre2 PDB 2csu chain A domain 1 Region: 167 - 283 Aligned: 109 Modelled: 117 Confidence: 35.9% Identity: 19% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 PDB 3fok chain H Region: 191 - 345 Aligned: 148 Modelled: 155 Confidence: 32.5% Identity: 11% PDB header:structural genomics, unknown function Chain: H: PDB Molecule:uncharacterized protein cgl0159; PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115 Phyre2 PDB 3njb chain A Region: 260 - 365 Aligned: 105 Modelled: 106 Confidence: 30.5% Identity: 10% PDB header:lyase Chain: A: PDB Molecule:enoyl-coa hydratase; PDBTitle: crystal structure of enoyl-coa hydratase from mycobacterium smegmatis,2 iodide soak Phyre2 PDB 3oqh chain B Region: 30 - 56 Aligned: 27 Modelled: 27 Confidence: 28.6% Identity: 19% PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein yvmc; PDBTitle: crystal structure of b. licheniformis cdps yvmc-blic Phyre2 PDB 2bh7 chain A Region: 198 - 231 Aligned: 33 Modelled: 34 Confidence: 28.1% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: crystal structure of a semet derivative of amid at 2.22 angstroms Phyre2 PDB 2duw chain A Region: 226 - 287 Aligned: 47 Modelled: 62 Confidence: 28.0% Identity: 28% PDB header:ligand binding protein Chain: A: PDB Molecule:putative coa-binding protein; PDBTitle: solution structure of putative coa-binding protein of2 klebsiella pneumoniae Phyre2 PDB 1j3b chain A domain 1 Region: 310 - 377 Aligned: 66 Modelled: 68 Confidence: 26.5% Identity: 18% Fold: PEP carboxykinase-like Superfamily: PEP carboxykinase-like Family: PEP carboxykinase C-terminal domain Phyre2 PDB 3pcs chain B Region: 148 - 210 Aligned: 59 Modelled: 63 Confidence: 26.2% Identity: 27% PDB header:protein transport/transferase Chain: B: PDB Molecule:espg; PDBTitle: structure of espg-pak2 autoinhibitory ialpha3 helix complex Phyre2 PDB 3qd5 chain B Region: 266 - 302 Aligned: 37 Modelled: 37 Confidence: 23.7% Identity: 24% PDB header:isomerase Chain: B: PDB Molecule:putative ribose-5-phosphate isomerase; PDBTitle: crystal structure of a putative ribose-5-phosphate isomerase from2 coccidioides immitis solved by combined iodide ion sad and mr Phyre2 PDB 1iuk chain A Region: 233 - 284 Aligned: 37 Modelled: 50 Confidence: 21.7% Identity: 24% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: CoA-binding domain Phyre2 1 c3abqA_ 2 c2qezC_ 3 d1eexa_ 4 d1iwpa_ 5 c3bwwA_ 6 c3bq7A_ 7 c2fpgA_ 8 c1v85A_ 9 c2nu8D_ 10 c3qmlC_ 11 d2csua1 12 c3fokH_ 13 c3njbA_ 14 c3oqhB_ 15 c2bh7A_ 16 c2duwA_ 17 d1j3ba1 18 c3pcsB_ 19 c3qd5B_ 20 d1iuka_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3abqA_ 100.0 100 PDB header:lyase Chain: A: PDB Molecule:ethanolamine ammonia-lyase heavy chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with cn-cbl and 2-amino-1-propanol 2 c2qezC_ 100.0 60 PDB header:lyase Chain: C: PDB Molecule:ethanolamine ammonia-lyase heavy chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase heavy chain2 (yp_013784.1) from listeria monocytogenes 4b f2365 at 2.15 a3 resolution 3 d1eexa_ 94.6 16 Fold:TIM beta/alpha-barrel Superfamily:Cobalamin (vitamin B12)-dependent enzymes Family:Diol dehydratase, alpha subunit 4 d1iwpa_ 93.9 18 Fold:TIM beta/alpha-barrel Superfamily:Cobalamin (vitamin B12)-dependent enzymes Family:Diol dehydratase, alpha subunit 5 c3bwwA_ 53.4 16 PDB header:metal binding protein Chain: A: PDB Molecule:protein of unknown function duf692/cog3220; PDBTitle: crystal structure of a duf692 family protein (hs_1138) from2 haemophilus somnus 129pt at 2.20 a resolution 6 c3bq7A_ 51.1 16 PDB header:transferase Chain: A: PDB Molecule:diacylglycerol kinase delta; PDBTitle: sam domain of diacylglycerol kinase delta1 (e35g) 7 c2fpgA_ 43.0 22 PDB header:ligase Chain: A: PDB Molecule:succinyl-coa ligase [gdp-forming] alpha-chain, PDBTitle: crystal structure of pig gtp-specific succinyl-coa2 synthetase in complex with gdp 8 c1v85A_ 39.8 10 PDB header:apoptosis Chain: A: PDB Molecule:similar to ring finger protein 36; PDBTitle: sterile alpha motif (sam) domain of mouse bifunctional2 apoptosis regulator 9 c2nu8D_ 37.2 21 PDB header:ligase Chain: D: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha; PDBTitle: c123at mutant of e. coli succinyl-coa synthetase 10 c3qmlC_ 35.9 17 PDB header:chaperone/protein transport Chain: C: PDB Molecule:nucleotide exchange factor sil1; PDBTitle: the structural analysis of sil1-bip complex reveals the mechanism for2 sil1 to function as a novel nucleotide exchange factor 11 d2csua1 35.9 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 12 c3fokH_ 32.5 11 PDB header:structural genomics, unknown function Chain: H: PDB Molecule:uncharacterized protein cgl0159; PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115 13 c3njbA_ 30.5 10 PDB header:lyase Chain: A: PDB Molecule:enoyl-coa hydratase; PDBTitle: crystal structure of enoyl-coa hydratase from mycobacterium smegmatis,2 iodide soak 14 c3oqhB_ 28.6 19 PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein yvmc; PDBTitle: crystal structure of b. licheniformis cdps yvmc-blic 15 c2bh7A_ 28.1 15 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: crystal structure of a semet derivative of amid at 2.22 angstroms 16 c2duwA_ 28.0 28 PDB header:ligand binding protein Chain: A: PDB Molecule:putative coa-binding protein; PDBTitle: solution structure of putative coa-binding protein of2 klebsiella pneumoniae 17 d1j3ba1 26.5 18 Fold:PEP carboxykinase-like Superfamily:PEP carboxykinase-like Family:PEP carboxykinase C-terminal domain 18 c3pcsB_ 26.2 27 PDB header:protein transport/transferase Chain: B: PDB Molecule:espg; PDBTitle: structure of espg-pak2 autoinhibitory ialpha3 helix complex 19 c3qd5B_ 23.7 24 PDB header:isomerase Chain: B: PDB Molecule:putative ribose-5-phosphate isomerase; PDBTitle: crystal structure of a putative ribose-5-phosphate isomerase from2 coccidioides immitis solved by combined iodide ion sad and mr 20 d1iuka_ 21.7 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 21 d1o1xa_ not modelled 21.1 22 Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB 22 c1ye9E_ not modelled 20.5 25 PDB header:oxidoreductase Chain: E: PDB Molecule:catalase hpii; PDBTitle: crystal structure of proteolytically truncated catalase2 hpii from e. coli 23 c3bs5A_ not modelled 20.4 14 PDB header:signaling protein/membrane protein Chain: A: PDB Molecule:protein aveugle; PDBTitle: crystal structure of hcnk2-sam/dhyp-sam complex 24 d1pk1c1 not modelled 18.8 21 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 25 c2iufA_ not modelled 18.2 25 PDB header:oxidoreductase Chain: A: PDB Molecule:catalase; PDBTitle: the structures of penicillium vitale catalase: resting2 state, oxidised state (compound i) and complex with3 aminotriazole 26 d1a4ea_ not modelled 18.2 17 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 27 c1zcjA_ not modelled 17.8 23 PDB header:oxidoreductase Chain: A: PDB Molecule:peroxisomal bifunctional enzyme; PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase 28 d1y81a1 not modelled 17.6 37 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 29 c3oqvA_ not modelled 17.4 27 PDB header:protein binding Chain: A: PDB Molecule:albc; PDBTitle: albc, a cyclodipeptide synthase from streptomyces noursei 30 d1si8a_ not modelled 17.0 25 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 31 d1sqia2 not modelled 17.0 19 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Extradiol dioxygenases 32 d1e93a_ not modelled 16.9 25 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 33 d1dkua1 not modelled 16.5 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 34 d1gwea_ not modelled 16.5 38 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 35 d4blca_ not modelled 16.4 33 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 36 d1p80a2 not modelled 16.4 25 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 37 c3ej6D_ not modelled 16.4 25 PDB header:oxidoreductase Chain: D: PDB Molecule:catalase-3; PDBTitle: neurospora crassa catalase-3 crystal structure 38 d1qwla_ not modelled 16.2 29 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 39 d1otha2 not modelled 16.1 10 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 40 c3lq1A_ not modelled 16.0 21 PDB header:transferase Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- PDBTitle: crystal structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene2 1-carboxylic acid synthase/2-oxoglutarate decarboxylase3 from listeria monocytogenes str. 4b f2365 41 c2pc9B_ not modelled 15.6 21 PDB header:lyase Chain: B: PDB Molecule:phosphoenolpyruvate carboxykinase [atp]; PDBTitle: crystal structure of atp-dependent phosphoenolpyruvate carboxykinase2 from thermus thermophilus hb8 42 c1sy7B_ not modelled 15.5 29 PDB header:oxidoreductase Chain: B: PDB Molecule:catalase 1; PDBTitle: crystal structure of the catalase-1 from neurospora crassa, native2 structure at 1.75a resolution. 43 d1mj3a_ not modelled 15.2 20 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Crotonase-like 44 d1m7sa_ not modelled 15.1 25 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 45 c2j2mD_ not modelled 14.7 29 PDB header:oxidoreductase Chain: D: PDB Molecule:catalase; PDBTitle: crystal structure analysis of catalase from exiguobacterium2 oxidotolerans 46 c2kp7A_ not modelled 14.4 50 PDB header:hydrolase Chain: A: PDB Molecule:crossover junction endonuclease mus81; PDBTitle: solution nmr structure of the mus81 n-terminal hhh.2 northeast structural genomics consortium target mmt1a 47 d1ofua2 not modelled 14.2 32 Fold:Bacillus chorismate mutase-like Superfamily:Tubulin C-terminal domain-like Family:Tubulin, C-terminal domain 48 c2dhmA_ not modelled 14.2 10 PDB header:protein binding Chain: A: PDB Molecule:protein bola; PDBTitle: solution structure of the bola protein from escherichia coli 49 c1p81A_ not modelled 13.7 25 PDB header:oxidoreductase Chain: A: PDB Molecule:catalase hpii; PDBTitle: crystal structure of the d181e variant of catalase hpii2 from e. coli 50 c3tr3A_ not modelled 13.6 15 PDB header:unknown function Chain: A: PDB Molecule:bola; PDBTitle: structure of a bola protein homologue from coxiella burnetii 51 c2xq1M_ not modelled 13.6 29 PDB header:oxidoreductase Chain: M: PDB Molecule:peroxisomal catalase; PDBTitle: crystal structure of peroxisomal catalase from the yeast hansenula2 polymorpha 52 d1dgfa_ not modelled 13.6 33 Fold:Heme-dependent catalase-like Superfamily:Heme-dependent catalase-like Family:Heme-dependent catalases 53 c1xs3A_ not modelled 13.6 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein xc975; PDBTitle: solution structure analysis of the xc975 protein 54 c3mogA_ not modelled 13.4 19 PDB header:oxidoreductase Chain: A: PDB Molecule:probable 3-hydroxybutyryl-coa dehydrogenase; PDBTitle: crystal structure of 3-hydroxybutyryl-coa dehydrogenase from2 escherichia coli k12 substr. mg1655 55 d2ae9a1 not modelled 13.1 32 Fold:DNA polymerase III theta subunit-like Superfamily:DNA polymerase III theta subunit-like Family:DNA polymerase III theta subunit-like 56 c2gleA_ not modelled 12.9 11 PDB header:protein binding Chain: A: PDB Molecule:neurabin-1; PDBTitle: solution structure of neurabin sam domain 57 d1kw4a_ not modelled 12.7 13 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 58 c1f4jC_ not modelled 12.5 33 PDB header:oxidoreductase Chain: C: PDB Molecule:catalase; PDBTitle: structure of tetragonal crystals of human erythrocyte2 catalase 59 d1nxha_ not modelled 12.1 15 Fold:Hypothetical protein MTH393 Superfamily:Hypothetical protein MTH393 Family:Hypothetical protein MTH393 60 c3imoC_ not modelled 12.1 42 PDB header:unknown function Chain: C: PDB Molecule:integron cassette protein; PDBTitle: structure from the mobile metagenome of vibrio cholerae.2 integron cassette protein vch_cass14 61 d2f6qa1 not modelled 11.9 17 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Crotonase-like 62 c1pk1A_ not modelled 11.7 11 PDB header:transcription repression Chain: A: PDB Molecule:polyhomeotic-proximal chromatin protein; PDBTitle: hetero sam domain structure of ph and scm. 63 c3onoA_ not modelled 11.5 19 PDB header:isomerase Chain: A: PDB Molecule:ribose/galactose isomerase; PDBTitle: crystal structure of ribose-5-phosphate isomerase lacab_rpib from2 vibrio parahaemolyticus 64 d1yzya1 not modelled 11.5 16 Fold:YgbK-like Superfamily:YgbK-like Family:YgbK-like 65 d2f2aa1 not modelled 11.0 20 Fold:Amidase signature (AS) enzymes Superfamily:Amidase signature (AS) enzymes Family:Amidase signature (AS) enzymes 66 c2pzlB_ not modelled 10.9 15 PDB header:sugar binding protein Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase; PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp 67 d1ny8a_ not modelled 10.6 15 Fold:Alpha-lytic protease prodomain-like Superfamily:BolA-like Family:BolA-like 68 c3fksY_ not modelled 10.6 16 PDB header:hydrolase Chain: Y: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: yeast f1 atpase in the absence of bound nucleotides 69 d1wwva1 not modelled 10.1 7 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 70 c3c5yD_ not modelled 10.0 30 PDB header:isomerase Chain: D: PDB Molecule:ribose/galactose isomerase; PDBTitle: crystal structure of a putative ribose 5-phosphate isomerase2 (saro_3514) from novosphingobium aromaticivorans dsm at 1.81 a3 resolution 71 d2idob1 not modelled 9.5 29 Fold:DNA polymerase III theta subunit-like Superfamily:DNA polymerase III theta subunit-like Family:DNA polymerase III theta subunit-like 72 c3bs7A_ not modelled 9.5 14 PDB header:signaling protein Chain: A: PDB Molecule:protein aveugle; PDBTitle: crystal structure of the sterile alpha motif (sam) domain2 of hyphen/aveugle 73 c2la7A_ not modelled 9.5 29 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: nmr structure of the protein yp_557733.1 from burkholderia xenovorans 74 c2ppwA_ not modelled 9.3 17 PDB header:isomerase Chain: A: PDB Molecule:conserved domain protein; PDBTitle: the crystal structure of uncharacterized ribose 5-phosphate isomerase2 rpib from streptococcus pneumoniae 75 d1chka_ not modelled 9.2 17 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Chitosanase 76 c3dqqB_ not modelled 9.0 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative trna synthase; PDBTitle: the crystal structure of the putative trna synthase from salmonella2 typhimurium lt2 77 d1ucua_ not modelled 8.9 16 Fold:Phase 1 flagellin Superfamily:Phase 1 flagellin Family:Phase 1 flagellin 78 d2bgxa2 not modelled 8.9 15 Fold:N-acetylmuramoyl-L-alanine amidase-like Superfamily:N-acetylmuramoyl-L-alanine amidase-like Family:N-acetylmuramoyl-L-alanine amidase-like 79 c2dc0A_ not modelled 8.7 10 PDB header:hydrolase Chain: A: PDB Molecule:probable amidase; PDBTitle: crystal structure of amidase 80 c2d3tB_ not modelled 8.6 28 PDB header:lyase, oxidoreductase/transferase Chain: B: PDB Molecule:fatty oxidation complex alpha subunit; PDBTitle: fatty acid beta-oxidation multienzyme complex from2 pseudomonas fragi, form v 81 c2h2mA_ not modelled 8.4 16 PDB header:metal transport Chain: A: PDB Molecule:comm domain-containing protein 1; PDBTitle: solution structure of the n-terminal domain of commd12 (murr1) 82 c2wtbA_ not modelled 8.3 25 PDB header:oxidoreductase Chain: A: PDB Molecule:fatty acid multifunctional protein (atmfp2); PDBTitle: arabidopsis thaliana multifuctional protein, mfp2 83 c1v60A_ not modelled 8.2 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:riken cdna 1810037g04; PDBTitle: solution structure of bola1 protein from mus musculus 84 c3lfmA_ not modelled 8.1 28 PDB header:oxidoreductase Chain: A: PDB Molecule:protein fto; PDBTitle: crystal structure of the fat mass and obesity associated (fto) protein2 reveals basis for its substrate specificity 85 c3ayhB_ not modelled 8.0 12 PDB header:transcription Chain: B: PDB Molecule:dna-directed rna polymerase iii subunit rpc8; PDBTitle: crystal structure of the c17/25 subcomplex from s. pombe rna2 polymerase iii 86 d1se7a_ not modelled 7.7 29 Fold:DNA polymerase III theta subunit-like Superfamily:DNA polymerase III theta subunit-like Family:DNA polymerase III theta subunit-like 87 c2wa0A_ not modelled 7.6 33 PDB header:immune system Chain: A: PDB Molecule:melanoma-associated antigen 4; PDBTitle: crystal structure of the human magea4 88 d1t47a2 not modelled 7.5 23 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Extradiol dioxygenases 89 d1vmja_ not modelled 7.5 24 Fold:YjbQ-like Superfamily:YjbQ-like Family:YjbQ-like 90 d2vvpa1 not modelled 7.5 16 Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB 91 c2fvuA_ not modelled 7.5 50 PDB header:transcription Chain: A: PDB Molecule:regulatory protein sir3; PDBTitle: structure of the yeast sir3 bah domain 92 d1bqva_ not modelled 7.4 18 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:Pointed domain 93 c3n5lA_ not modelled 7.3 7 PDB header:transport protein Chain: A: PDB Molecule:binding protein component of abc phosphonate transporter; PDBTitle: crystal structure of a binding protein component of abc phosphonate2 transporter (pa3383) from pseudomonas aeruginosa at 1.97 a resolution 94 c3gebC_ not modelled 7.1 27 PDB header:hydrolase Chain: C: PDB Molecule:eyes absent homolog 2; PDBTitle: crystal structure of edeya2 95 c2yv1A_ not modelled 7.1 19 PDB header:ligase Chain: A: PDB Molecule:succinyl-coa ligase [adp-forming] subunit alpha; PDBTitle: crystal structure of succinyl-coa synthetase alpha chain from2 methanocaldococcus jannaschii dsm 2661 96 c2kveA_ not modelled 6.8 19 PDB header:hormone Chain: A: PDB Molecule:mesencephalic astrocyte-derived neurotrophic factor; PDBTitle: c-terminal domain of mesencephalic astrocyte-derived neurotrophic2 factor (manf) 97 d1sp9a_ not modelled 6.8 23 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Family:Extradiol dioxygenases 98 d1b33b_ not modelled 6.7 25 Fold:Globin-like Superfamily:Globin-like Family:Phycocyanin-like phycobilisome proteins 99 d1u1ha1 not modelled 6.7 24 Fold:TIM beta/alpha-barrel Superfamily:UROD/MetE-like Family:Cobalamin-independent methionine synthase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0