Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP16659
DateThu Jan 5 11:35:16 GMT 2012
Unique Job ID3069899d04574522

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2j3mA_
Top template information
PDB header:ligase
Chain: A: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol
Confidence and coverage
Confidence:100.0% Coverage: 97%
552 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREE
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Disorder  ????







?
??











































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   .........70.........80.........90.........100.........110.........120
Sequence  MNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRN
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??








??
































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   .........130.........140.........150.........160.........170.........180
Sequence  ELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAA
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   .........190.........200.........210.........220.........230.........240
Sequence  YSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIA
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????































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   .........250.........260.........270.........280.........290.........300
Sequence  PKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPQVALLVRG
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   .........310.........320.........330.........340.........350.........360
Sequence  DHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFA
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??










































?



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   .........370.........380.........390.........400.........410.........420
Sequence  AGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGRLLIKRGIEVGHIFQLGTK
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   .........430.........440.........450.........460.........470.........480
Sequence  YSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILP
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   .........490.........500.........510.........520.........530.........540
Sequence  MNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLD
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   .........550.........560.........570..
Sequence  NDDIEYKYRRNGEKQLIKTGDIVEYLVKQIKG
Secondary structure 









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Disorder 




























???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2j3m chain A

3D model

Region: 1 - 570
Aligned: 552
Modelled: 570
Confidence: 100.0%
Identity: 46%
PDB header:ligase
Chain: A: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol

Phyre2

PDB 2i4l chain C

3D model

Region: 1 - 566
Aligned: 437
Modelled: 438
Confidence: 100.0%
Identity: 51%
PDB header:ligase
Chain: C: PDB Molecule:proline-trna ligase;
PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase

Phyre2

PDB 1ggm chain B

3D model

Region: 24 - 571
Aligned: 378
Modelled: 380
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: B: PDB Molecule:protein (glycyl-trna synthetase);
PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate

Phyre2

PDB 3ial chain B

3D model

Region: 10 - 571
Aligned: 374
Modelled: 375
Confidence: 100.0%
Identity: 26%
PDB header:ligase
Chain: B: PDB Molecule:prolyl-trna synthetase;
PDBTitle: giardia lamblia prolyl-trna synthetase in complex with prolyl-2 adenylate

Phyre2

PDB 1nyq chain A

3D model

Region: 17 - 571
Aligned: 396
Modelled: 409
Confidence: 100.0%
Identity: 23%
PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase 1;
PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate

Phyre2

PDB 2pmf chain A

3D model

Region: 21 - 572
Aligned: 401
Modelled: 403
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: A: PDB Molecule:glycyl-trna synthetase;
PDBTitle: the crystal structure of a human glycyl-trna synthetase mutant

Phyre2

PDB 1qf6 chain A

3D model

Region: 17 - 572
Aligned: 391
Modelled: 401
Confidence: 100.0%
Identity: 23%
PDB header:ligase/rna
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna

Phyre2

PDB 1ati chain A

3D model

Region: 24 - 571
Aligned: 378
Modelled: 380
Confidence: 100.0%
Identity: 20%
PDB header:protein biosynthesis
Chain: A: PDB Molecule:glycyl-trna synthetase;
PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus

Phyre2

PDB 1nj8 chain C

3D model

Region: 23 - 571
Aligned: 360
Modelled: 362
Confidence: 100.0%
Identity: 27%
PDB header:ligase
Chain: C: PDB Molecule:proline-trna synthetase;
PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii

Phyre2

PDB 1h4t chain D

3D model

Region: 23 - 571
Aligned: 355
Modelled: 362
Confidence: 100.0%
Identity: 25%
PDB header:aminoacyl-trna synthetase
Chain: D: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from thermus thermophilus complexed2 with l-proline

Phyre2

PDB 1nj2 chain A

3D model

Region: 23 - 571
Aligned: 354
Modelled: 362
Confidence: 100.0%
Identity: 28%
PDB header:ligase
Chain: A: PDB Molecule:proline-trna synthetase;
PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus

Phyre2

PDB 3a32 chain A

3D model

Region: 17 - 569
Aligned: 411
Modelled: 424
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: A: PDB Molecule:probable threonyl-trna synthetase 1;
PDBTitle: crystal structure of putative threonyl-trna synthetase2 thrrs-1 from aeropyrum pernix

Phyre2

PDB 1fyf chain B

3D model

Region: 21 - 572
Aligned: 387
Modelled: 397
Confidence: 100.0%
Identity: 23%
PDB header:ligase
Chain: B: PDB Molecule:threonyl-trna synthetase;
PDBTitle: crystal structure of a truncated form of threonyl-trna2 synthetase complexed with a seryl adenylate analog

Phyre2

PDB 3ikm chain C

3D model

Region: 14 - 570
Aligned: 358
Modelled: 361
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: C: PDB Molecule:dna polymerase subunit gamma-2;
PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme

Phyre2

PDB 1g5h chain A

3D model

Region: 24 - 570
Aligned: 353
Modelled: 363
Confidence: 100.0%
Identity: 22%
PDB header:dna binding protein
Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit;
PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma

Phyre2

PDB 1ady chain A

3D model

Region: 34 - 570
Aligned: 415
Modelled: 434
Confidence: 100.0%
Identity: 18%
PDB header:trna synthetase
Chain: A: PDB Molecule:histidyl-trna synthetase;
PDBTitle: histidyl-trna synthetase in complex with histidyl-adenylate

Phyre2

PDB 2el9 chain B

3D model

Region: 33 - 570
Aligned: 369
Modelled: 392
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of e.coli histidyl-trna synthetase2 complexed with a histidyl-adenylate analogue

Phyre2

PDB 1wu7 chain A

3D model

Region: 31 - 570
Aligned: 421
Modelled: 444
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: A: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of histidyl-trna synthetase from2 thermoplasma acidophilum

Phyre2

PDB 3net chain B

3D model

Region: 33 - 570
Aligned: 413
Modelled: 438
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of histidyl-trna synthetase from nostoc sp. pcc 7120

Phyre2

PDB 3hri chain F

3D model

Region: 34 - 560
Aligned: 366
Modelled: 398
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: F: PDB Molecule:histidyl-trna synthetase;
PDBTitle: histidyl-trna synthetase (apo) from trypanosoma brucei

Phyre2
1

c2j3mA_
2

c2i4lC_
3

c1ggmB_
4

c3ialB_
5

c1nyqA_
6

c2pmfA_
7

c1qf6A_
8

c1atiA_
9

c1nj8C_
10

c1h4tD_
11

c1nj2A_
12

c3a32A_
13

c1fyfB_
14

c3ikmC_
15

c1g5hA_
16

c1adyA_
17

c2el9B_
18

c1wu7A_
19

c3netB_
20

c3hriF_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2j3mA_



100.0 46 PDB header:ligase
Chain: A: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol
2c2i4lC_



100.0 51 PDB header:ligase
Chain: C: PDB Molecule:proline-trna ligase;
PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase
3c1ggmB_



100.0 20 PDB header:ligase
Chain: B: PDB Molecule:protein (glycyl-trna synthetase);
PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate
4c3ialB_



100.0 26 PDB header:ligase
Chain: B: PDB Molecule:prolyl-trna synthetase;
PDBTitle: giardia lamblia prolyl-trna synthetase in complex with prolyl-2 adenylate
5c1nyqA_



100.0 23 PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase 1;
PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate
6c2pmfA_



100.0 20 PDB header:ligase
Chain: A: PDB Molecule:glycyl-trna synthetase;
PDBTitle: the crystal structure of a human glycyl-trna synthetase mutant
7c1qf6A_



100.0 23 PDB header:ligase/rna
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna
8c1atiA_



100.0 20 PDB header:protein biosynthesis
Chain: A: PDB Molecule:glycyl-trna synthetase;
PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus
9c1nj8C_



100.0 27 PDB header:ligase
Chain: C: PDB Molecule:proline-trna synthetase;
PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii
10c1h4tD_



100.0 25 PDB header:aminoacyl-trna synthetase
Chain: D: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from thermus thermophilus complexed2 with l-proline
11c1nj2A_



100.0 28 PDB header:ligase
Chain: A: PDB Molecule:proline-trna synthetase;
PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus
12c3a32A_



100.0 18 PDB header:ligase
Chain: A: PDB Molecule:probable threonyl-trna synthetase 1;
PDBTitle: crystal structure of putative threonyl-trna synthetase2 thrrs-1 from aeropyrum pernix
13c1fyfB_



100.0 23 PDB header:ligase
Chain: B: PDB Molecule:threonyl-trna synthetase;
PDBTitle: crystal structure of a truncated form of threonyl-trna2 synthetase complexed with a seryl adenylate analog
14c3ikmC_



100.0 18 PDB header:transferase
Chain: C: PDB Molecule:dna polymerase subunit gamma-2;
PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme
15c1g5hA_



100.0 22 PDB header:dna binding protein
Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit;
PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma
16c1adyA_



100.0 18 PDB header:trna synthetase
Chain: A: PDB Molecule:histidyl-trna synthetase;
PDBTitle: histidyl-trna synthetase in complex with histidyl-adenylate
17c2el9B_



100.0 18 PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of e.coli histidyl-trna synthetase2 complexed with a histidyl-adenylate analogue
18c1wu7A_



100.0 19 PDB header:ligase
Chain: A: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of histidyl-trna synthetase from2 thermoplasma acidophilum
19c3netB_



100.0 18 PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of histidyl-trna synthetase from nostoc sp. pcc 7120
20c3hriF_



100.0 18 PDB header:ligase
Chain: F: PDB Molecule:histidyl-trna synthetase;
PDBTitle: histidyl-trna synthetase (apo) from trypanosoma brucei
21c1qe0B_



not modelled 100.0 27 PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of apo s. aureus histidyl-trna synthetase
22d1nj1a3



not modelled 100.0 25 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
23d1nj8a3



not modelled 100.0 24 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
24c3od1A_



not modelled 100.0 18 PDB header:transferase
Chain: A: PDB Molecule:atp phosphoribosyltransferase regulatory subunit;
PDBTitle: the crystal structure of an atp phosphoribosyltransferase regulatory2 subunit/histidyl-trna synthetase from bacillus halodurans c
25d1qf6a4



not modelled 100.0 21 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
26d1hc7a2



not modelled 100.0 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
27d1nyra4



not modelled 100.0 23 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
28c2cj9A_



not modelled 100.0 27 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of methanosarcina barkeri seryl-trna2 synthetase complexed with an analog of seryladenylate
29d1atia2



not modelled 100.0 22 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
30d1b76a2



not modelled 100.0 22 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
31d1seta2



not modelled 100.0 22 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
32c3mf2B_



not modelled 100.0 17 PDB header:ligase
Chain: B: PDB Molecule:bll0957 protein;
PDBTitle: crystal structure of class ii aars homologue (bll0957) complexed with2 amp
33c1wleB_



not modelled 100.0 21 PDB header:ligase
Chain: B: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of mammalian mitochondrial seryl-trna2 synthetase complexed with seryl-adenylate
34c1sryB_



not modelled 100.0 21 PDB header:ligase(synthetase)
Chain: B: PDB Molecule:seryl-trna synthetase;
PDBTitle: refined crystal structure of the seryl-trna synthetase from2 thermus thermophilus at 2.5 angstroms resolution
35c3lssA_



not modelled 100.0 22 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp
36c3qo8A_



not modelled 100.0 23 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic;
PDBTitle: crystal structure of seryl-trna synthetase from candida albicans
37c2dq0A_



not modelled 100.0 23 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog
38c2dq3A_



not modelled 100.0 26 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of aq_298
39c3errB_



not modelled 100.0 22 PDB header:ligase
Chain: B: PDB Molecule:fusion protein of microtubule binding domain from
PDBTitle: microtubule binding domain from mouse cytoplasmic dynein as2 a fusion with seryl-trna synthetase
40d1wu7a2



not modelled 100.0 21 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
41d1z7ma1



not modelled 100.0 13 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
42d1kmma2



not modelled 100.0 17 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
43d1g5ha2



not modelled 100.0 25 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
44c1z7nB_



not modelled 100.0 14 PDB header:transferase
Chain: B: PDB Molecule:atp phosphoribosyltransferase regulatory subunit;
PDBTitle: atp phosphoribosyl transferase (hiszg atp-prtase) from2 lactococcus lactis with bound prpp substrate
45c3racA_



not modelled 100.0 15 PDB header:ligase
Chain: A: PDB Molecule:histidine-trna ligase;
PDBTitle: crystal strucutre of histidine--trna ligase subunit from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446.
46d1h4vb2



not modelled 100.0 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
47d2g4ca2



not modelled 100.0 19 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
48d1qe0a2



not modelled 100.0 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
49d1nj1a1



not modelled 100.0 33 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
50d1nj8a1



not modelled 100.0 32 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
51c3g1zB_



not modelled 100.0 18 PDB header:ligase
Chain: B: PDB Molecule:putative lysyl-trna synthetase;
PDBTitle: structure of idp01693/yjea, a potential t-rna synthetase from2 salmonella typhimurium
52d1usya_



not modelled 100.0 16 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
53d1bbua2



not modelled 100.0 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
54d1hc7a1



not modelled 100.0 38 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
55d1e1oa2



not modelled 99.9 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
56d1nyra1



not modelled 99.9 29 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
57d1qf6a1



not modelled 99.9 26 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
58d1g5ha1



not modelled 99.9 17 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
59d1atia1



not modelled 99.9 19 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
60d2g4ca1



not modelled 99.9 20 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
61d1eova2



not modelled 99.9 19 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
62c2zimA_



not modelled 99.9 18 PDB header:ligase
Chain: A: PDB Molecule:pyrrolysyl-trna synthetase;
PDBTitle: pyrrolysyl-trna synthetase bound to adenylated pyrrolysine and2 pyrophosphate
63d1kmma1



not modelled 99.9 19 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
64d1wu7a1



not modelled 99.8 17 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
65d1qe0a1



not modelled 99.8 30 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
66d1h4vb1



not modelled 99.8 16 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
67d1b8aa2



not modelled 99.8 13 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
68c2znjB_



not modelled 99.8 18 PDB header:ligase
Chain: B: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of pyrrolysyl-trna synthetase from2 desulfitobacterium hafniense
69d1l0wa3



not modelled 99.8 18 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
70d1nnha_



not modelled 99.7 13 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
71d1c0aa3



not modelled 99.7 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
72c1e22A_



not modelled 99.7 20 PDB header:ligase
Chain: A: PDB Molecule:lysyl-trna synthetase;
PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp
73c1b70A_



not modelled 99.7 14 PDB header:ligase
Chain: A: PDB Molecule:phenylalanyl-trna synthetase;
PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine
74d1jjca_



not modelled 99.6 14 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
75c3l4gI_



not modelled 99.6 14 PDB header:ligase
Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain;
PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase
76c3bjuB_



not modelled 99.5 16 PDB header:ligase
Chain: B: PDB Molecule:lysyl-trna synthetase;
PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase
77c3e9hB_



not modelled 99.4 17 PDB header:ligase
Chain: B: PDB Molecule:lysyl-trna synthetase;
PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine
78c1asyA_



not modelled 99.3 14 PDB header:complex (aminoacyl-trna synthase/trna)
Chain: A: PDB Molecule:aspartyl-trna synthetase;
PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp
79c1eqrC_



not modelled 99.1 21 PDB header:ligase
Chain: C: PDB Molecule:aspartyl-trna synthetase;
PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli
80c2rhqA_



not modelled 99.1 8 PDB header:ligase
Chain: A: PDB Molecule:phenylalanyl-trna synthetase alpha chain;
PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies
81c1efwA_



not modelled 99.1 19 PDB header:ligase/rna
Chain: A: PDB Molecule:aspartyl-trna synthetase;
PDBTitle: crystal structure of aspartyl-trna synthetase from thermus2 thermophilus complexed to trnaasp from escherichia coli
82c2xgtB_



not modelled 99.1 22 PDB header:ligase
Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic;
PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate
83c1x55A_



not modelled 99.0 17 PDB header:ligase
Chain: A: PDB Molecule:asparaginyl-trna synthetase;
PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue
84c1b8aB_



not modelled 99.0 20 PDB header:ligase
Chain: B: PDB Molecule:protein (aspartyl-trna synthetase);
PDBTitle: aspartyl-trna synthetase
85c1wydB_



not modelled 98.9 14 PDB header:ligase
Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase;
PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii
86c3m4qA_



not modelled 98.9 16 PDB header:ligase
Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative;
PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs)
87c2du4B_



not modelled 98.8 14 PDB header:ligase/rna
Chain: B: PDB Molecule:o-phosphoseryl-trna synthetase;
PDBTitle: crystal structure of archaeoglobus fulgidus o-phosphoseryl-2 trna synthetase complexed with trnacys
88c3i7fA_



not modelled 98.8 16 PDB header:ligase
Chain: A: PDB Molecule:aspartyl-trna synthetase;
PDBTitle: aspartyl trna synthetase from entamoeba histolytica
89c2du7C_



not modelled 98.6 14 PDB header:ligase
Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase;
PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase
90c1n9wA_



not modelled 98.5 19 PDB header:biosynthetic protein
Chain: A: PDB Molecule:aspartyl-trna synthetase 2;
PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus
91c3pcoC_



not modelled 98.5 9 PDB header:ligase
Chain: C: PDB Molecule:phenylalanyl-trna synthetase, alpha subunit;
PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp
92c3ig2B_



not modelled 98.5 15 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: the crystal structure of a putative phenylalanyl-trna synthetase2 (phers) beta chain domain from bacteroides fragilis to 2.1a
93d1v95a_



not modelled 98.4 15 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
94c3icaB_



not modelled 98.4 13 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: the crystal structure of the beta subunit of a phenylalanyl-trna2 synthetase from porphyromonas gingivalis w83
95c3l4gL_



not modelled 98.2 14 PDB header:ligase
Chain: L: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase
96d1jjcb5



not modelled 97.9 15 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
97d1wdva_



not modelled 97.8 25 Fold:YbaK/ProRS associated domain
Superfamily:YbaK/ProRS associated domain
Family:YbaK/ProRS associated domain
98d1n9wa2



not modelled 97.7 25 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
99c2rhsB_



not modelled 97.5 10 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies
100c2dxaA_



not modelled 97.4 18 PDB header:translation
Chain: A: PDB Molecule:protein ybak;
PDBTitle: crystal structure of trans editing enzyme prox from e.coli
101d1dbxa_



not modelled 97.2 22 Fold:YbaK/ProRS associated domain
Superfamily:YbaK/ProRS associated domain
Family:YbaK/ProRS associated domain
102d1vkia_



not modelled 97.1 19 Fold:YbaK/ProRS associated domain
Superfamily:YbaK/ProRS associated domain
Family:YbaK/ProRS associated domain
103c2cx5B_



not modelled 97.1 26 PDB header:translation
Chain: B: PDB Molecule:a putative trans-editing enzyme;
PDBTitle: crystal structure of a putative trans-editing enzyme for2 prolyl trna synthetase
104c3cmqA_



not modelled 96.6 17 PDB header:ligase
Chain: A: PDB Molecule:phenylalanyl-trna synthetase, mitochondrial;
PDBTitle: crystal structure of human mitochondrial phenylalanine trna2 synthetase
105d1vjfa_



not modelled 96.1 17 Fold:YbaK/ProRS associated domain
Superfamily:YbaK/ProRS associated domain
Family:YbaK/ProRS associated domain
106c3pcoD_



not modelled 96.1 12 PDB header:ligase
Chain: D: PDB Molecule:phenylalanyl-trna synthetase, beta chain;
PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp
107c2akwB_



not modelled 95.9 15 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: crystal structure of t.thermophilus phenylalanyl-trna synthetase2 complexed with p-cl-phenylalanine
108c3op6B_



not modelled 87.9 18 PDB header:unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an oligo-nucleotide binding protein (lpg1207)2 from legionella pneumophila subsp. pneumophila str. philadelphia 1 at3 2.00 a resolution
109d1mkza_



not modelled 79.5 11 Fold:Molybdenum cofactor biosynthesis proteins
Superfamily:Molybdenum cofactor biosynthesis proteins
Family:MogA-like
110c3h16A_



not modelled 61.6 21 PDB header:signaling protein
Chain: A: PDB Molecule:tir protein;
PDBTitle: crystal structure of a bacteria tir domain, pdtir from2 paracoccus denitrificans
111c1zejA_



not modelled 56.9 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the 3-hydroxyacyl-coa dehydrogenase (hbd-9,2 af2017) from archaeoglobus fulgidus dsm 4304 at 2.00 a resolution
112c3pfnB_



not modelled 52.1 18 PDB header:transferase
Chain: B: PDB Molecule:nad kinase;
PDBTitle: crystal structure of human nad kinase
113d1y5ea1



not modelled 46.9 13 Fold:Molybdenum cofactor biosynthesis proteins
Superfamily:Molybdenum cofactor biosynthesis proteins
Family:MogA-like
114c3mogA_



not modelled 45.2 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxybutyryl-coa dehydrogenase;
PDBTitle: crystal structure of 3-hydroxybutyryl-coa dehydrogenase from2 escherichia coli k12 substr. mg1655
115d1f0ya1



not modelled 40.9 15 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like
Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like
Family:HCDH C-domain-like
116d2cvba1



not modelled 39.7 15 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:Glutathione peroxidase-like
117c2is8A_



not modelled 35.0 19 PDB header:structural protein
Chain: A: PDB Molecule:molybdopterin biosynthesis enzyme, moab;
PDBTitle: crystal structure of the molybdopterin biosynthesis enzyme moab2 (ttha0341) from thermus theromophilus hb8
118c3rfqC_



not modelled 28.4 8 PDB header:biosynthetic protein
Chain: C: PDB Molecule:pterin-4-alpha-carbinolamine dehydratase moab2;
PDBTitle: crystal structure of pterin-4-alpha-carbinolamine dehydratase moab22 from mycobacterium marinum
119c3oziB_



not modelled 27.6 17 PDB header:plant protein
Chain: B: PDB Molecule:l6tr;
PDBTitle: crystal structure of the tir domain from the flax disease resistance2 protein l6
120d1m5wa_



not modelled 27.4 15 Fold:TIM beta/alpha-barrel
Superfamily:Pyridoxine 5'-phosphate synthase
Family:Pyridoxine 5'-phosphate synthase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0