Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP28638
DateThu Jan 5 11:45:07 GMT 2012
Unique Job ID1c116336b7d464ae

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1nw6A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:modification methylase rsri;
PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin
Confidence and coverage
Confidence:100.0% Coverage: 83%
244 residues ( 83% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYNIGKNFDGLIEAWKEDL
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Disorder  ???????







































??????????


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   .........70.........80.........90.........100.........110.........120
Sequence  FIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLFTIKSRIVWSYDSSGVQAK
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????
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   .........130.........140.........150.........160.........170.........180
Sequence  KHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALIDYRKNPPQPYNHQKVPGNVW
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?????






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   .........190.........200.........210.........220.........230.........240
Sequence  DFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIVLDPFAGSFTTGAVAIASGRKFI
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   .........250.........260.........270.........280.........290....
Sequence  GIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTGNLSKRSRLSEVDPDLITK
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Disorder 



















???







??????????

??
????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1nw6 chain A

3D model

Region: 11 - 261
Aligned: 244
Modelled: 246
Confidence: 100.0%
Identity: 31%
PDB header:transferase
Chain: A: PDB Molecule:modification methylase rsri;
PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin

Phyre2

PDB 1eg2 chain A

3D model

Region: 11 - 263
Aligned: 246
Modelled: 248
Confidence: 100.0%
Identity: 31%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Type II DNA methylase

Phyre2

PDB 1g60 chain A

3D model

Region: 13 - 258
Aligned: 235
Modelled: 246
Confidence: 100.0%
Identity: 32%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Type II DNA methylase

Phyre2

PDB 1boo chain A

3D model

Region: 10 - 279
Aligned: 242
Modelled: 245
Confidence: 100.0%
Identity: 23%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Type II DNA methylase

Phyre2

PDB 2zif chain B

3D model

Region: 14 - 259
Aligned: 214
Modelled: 231
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: B: PDB Molecule:putative modification methylase;
PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine

Phyre2

PDB 3ldu chain A

3D model

Region: 180 - 259
Aligned: 80
Modelled: 80
Confidence: 98.7%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:putative methylase;
PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630.

Phyre2

PDB 3k0b chain A

3D model

Region: 194 - 259
Aligned: 66
Modelled: 66
Confidence: 98.7%
Identity: 26%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:predicted n6-adenine-specific dna methylase;
PDBTitle: crystal structure of a predicted n6-adenine-specific dna methylase2 from listeria monocytogenes str. 4b f2365

Phyre2

PDB 3ldg chain A

3D model

Region: 195 - 259
Aligned: 65
Modelled: 65
Confidence: 98.7%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:putative uncharacterized protein smu.472;
PDBTitle: crystal structure of smu.472, a putative methyltransferase complexed2 with sah

Phyre2

PDB 3gdh chain C

3D model

Region: 200 - 258
Aligned: 59
Modelled: 59
Confidence: 98.5%
Identity: 27%
PDB header:transferase
Chain: C: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form)

Phyre2

PDB 2ar0 chain A domain 1

3D model

Region: 200 - 256
Aligned: 57
Modelled: 56
Confidence: 98.5%
Identity: 32%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: N-6 DNA Methylase-like

Phyre2

PDB 3egi chain A

3D model

Region: 200 - 258
Aligned: 59
Modelled: 59
Confidence: 98.4%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase tgs1 bound to m7gpppa (inactive form)

Phyre2

PDB 2fhp chain A domain 1

3D model

Region: 188 - 258
Aligned: 69
Modelled: 71
Confidence: 98.4%
Identity: 25%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: YhhF-like

Phyre2

PDB 1wy7 chain A domain 1

3D model

Region: 195 - 258
Aligned: 64
Modelled: 64
Confidence: 98.4%
Identity: 20%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Ta1320-like

Phyre2

PDB 3a27 chain A

3D model

Region: 205 - 257
Aligned: 53
Modelled: 53
Confidence: 98.3%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein mj1557;
PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet

Phyre2

PDB 3p9n chain A

3D model

Region: 201 - 258
Aligned: 58
Modelled: 58
Confidence: 98.3%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:possible methyltransferase (methylase);
PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase

Phyre2

PDB 2okc chain A domain 1

3D model

Region: 200 - 256
Aligned: 57
Modelled: 54
Confidence: 98.3%
Identity: 18%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: N-6 DNA Methylase-like

Phyre2

PDB 3khk chain A

3D model

Region: 200 - 256
Aligned: 57
Modelled: 57
Confidence: 98.2%
Identity: 23%
PDB header:dna binding protein
Chain: A: PDB Molecule:type i restriction-modification system
PDBTitle: crystal structure of type-i restriction-modification system2 methylation subunit (mm_0429) from methanosarchina mazei.

Phyre2

PDB 3mti chain A

3D model

Region: 198 - 259
Aligned: 62
Modelled: 62
Confidence: 98.2%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a

Phyre2

PDB 2ift chain A domain 1

3D model

Region: 201 - 258
Aligned: 56
Modelled: 58
Confidence: 98.2%
Identity: 23%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: YhhF-like

Phyre2

PDB 2frn chain A domain 1

3D model

Region: 205 - 257
Aligned: 53
Modelled: 53
Confidence: 98.2%
Identity: 23%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Met-10+ protein-like

Phyre2
1

c1nw6A_
2

d1eg2a_
3

d1g60a_
4

d1booa_
5

c2zifB_
6

c3lduA_
7

c3k0bA_
8

c3ldgA_
9

c3gdhC_
10

d2ar0a1
11

c3egiA_
12

d2fhpa1
13

d1wy7a1
14

c3a27A_
15

c3p9nA_
16

d2okca1
17

c3khkA_
18

c3mtiA_
19

d2ifta1
20

d2frna1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1nw6A_



100.0 31 PDB header:transferase
Chain: A: PDB Molecule:modification methylase rsri;
PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin
2d1eg2a_



100.0 31 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Type II DNA methylase
3d1g60a_



100.0 32 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Type II DNA methylase
4d1booa_



100.0 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Type II DNA methylase
5c2zifB_



100.0 26 PDB header:transferase
Chain: B: PDB Molecule:putative modification methylase;
PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine
6c3lduA_



98.7 25 PDB header:transferase
Chain: A: PDB Molecule:putative methylase;
PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630.
7c3k0bA_



98.7 26 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:predicted n6-adenine-specific dna methylase;
PDBTitle: crystal structure of a predicted n6-adenine-specific dna methylase2 from listeria monocytogenes str. 4b f2365
8c3ldgA_



98.7 26 PDB header:transferase
Chain: A: PDB Molecule:putative uncharacterized protein smu.472;
PDBTitle: crystal structure of smu.472, a putative methyltransferase complexed2 with sah
9c3gdhC_



98.5 27 PDB header:transferase
Chain: C: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form)
10d2ar0a1



98.5 32 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N-6 DNA Methylase-like
11c3egiA_



98.4 25 PDB header:transferase
Chain: A: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase tgs1 bound to m7gpppa (inactive form)
12d2fhpa1



98.4 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
13d1wy7a1



98.4 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ta1320-like
14c3a27A_



98.3 19 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein mj1557;
PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet
15c3p9nA_



98.3 24 PDB header:transferase
Chain: A: PDB Molecule:possible methyltransferase (methylase);
PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase
16d2okca1



98.3 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N-6 DNA Methylase-like
17c3khkA_



98.2 23 PDB header:dna binding protein
Chain: A: PDB Molecule:type i restriction-modification system
PDBTitle: crystal structure of type-i restriction-modification system2 methylation subunit (mm_0429) from methanosarchina mazei.
18c3mtiA_



98.2 15 PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a
19d2ifta1



98.2 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
20d2frna1



98.2 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Met-10+ protein-like
21c3a26A_



not modelled 98.2 23 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein ph0793;
PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado
22c3lkdB_



not modelled 98.1 19 PDB header:transferase
Chain: B: PDB Molecule:type i restriction-modification system
PDBTitle: crystal structure of the type i restriction-modification2 system methyltransferase subunit from streptococcus3 thermophilus, northeast structural genomics consortium4 target sur80
23c3lpmA_



not modelled 98.1 24 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of putative methyltransferase small domain protein2 from listeria monocytogenes
24d1ws6a1



not modelled 98.1 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
25d1ne2a_



not modelled 98.1 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ta1320-like
26c2yx1A_



not modelled 98.0 23 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein mj0883;
PDBTitle: crystal structure of m.jannaschii trna m1g37 methyltransferase
27c1aqjB_



not modelled 98.0 20 PDB header:methyltransferase
Chain: B: PDB Molecule:adenine-n6-dna-methyltransferase taqi;
PDBTitle: structure of adenine-n6-dna-methyltransferase taqi
28c1g38A_



not modelled 98.0 17 PDB header:transferase/dna
Chain: A: PDB Molecule:modification methylase taqi;
PDBTitle: adenine-specific methyltransferase m. taq i/dna complex
29d2as0a2



not modelled 98.0 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
30c3bt7A_



not modelled 98.0 9 PDB header:transferase/rna
Chain: A: PDB Molecule:trna (uracil-5-)-methyltransferase;
PDBTitle: structure of e. coli 5-methyluridine methyltransferase trma2 in complex with 19 nucleotide t-arm analogue
31c3s1sA_



not modelled 98.0 25 PDB header:hydrolase, transferase
Chain: A: PDB Molecule:restriction endonuclease bpusi;
PDBTitle: characterization and crystal structure of the type iig restriction2 endonuclease bpusi
32c2esrB_



not modelled 98.0 24 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: conserved hypothetical protein- streptococcus pyogenes
33d2nxca1



not modelled 98.0 26 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ribosomal protein L11 methyltransferase PrmA
34d2f8la1



not modelled 97.9 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N-6 DNA Methylase-like
35c3njrB_



not modelled 97.9 17 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y methylase;
PDBTitle: crystal structure of c-terminal domain of precorrin-6y c5,15-2 methyltransferase from rhodobacter capsulatus
36c3grzA_



not modelled 97.9 17 PDB header:transferase
Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase;
PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus
37d1uwva2



not modelled 97.9 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:(Uracil-5-)-methyltransferase
38d2fpoa1



not modelled 97.9 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
39c1wg8B_



not modelled 97.9 17 PDB header:transferase
Chain: B: PDB Molecule:predicted s-adenosylmethionine-dependent
PDBTitle: crystal structure of a predicted s-adenosylmethionine-2 dependent methyltransferase tt1512 from thermus3 thermophilus hb8.
40d1nv8a_



not modelled 97.9 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N5-glutamine methyltransferase, HemK
41d2b3ta1



not modelled 97.9 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N5-glutamine methyltransferase, HemK
42c2yvlB_



not modelled 97.8 22 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of trna (m1a58) methyltransferase trmi from aquifex2 aeolicus
43d1dusa_



not modelled 97.8 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical protein MJ0882
44d1wg8a2



not modelled 97.8 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:MraW-like putative methyltransferases
45d2ih2a1



not modelled 97.8 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:DNA methylase TaqI, N-terminal domain
46d1qama_



not modelled 97.8 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA adenine dimethylase-like
47c2vs1A_



not modelled 97.8 24 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized rna methyltransferase pyrab10780;
PDBTitle: the crystal structure of pyrococcus abyssi trna (uracil-54,2 c5)-methyltransferase in complex with s-adenosyl-l-3 homocysteine
48c3eeyJ_



not modelled 97.8 19 PDB header:transferase
Chain: J: PDB Molecule:putative rrna methylase;
PDBTitle: crystal structure of putative rrna-methylase from clostridium2 thermocellum
49c1uwvA_



not modelled 97.8 19 PDB header:transferase
Chain: A: PDB Molecule:23s rrna (uracil-5-)-methyltransferase ruma;
PDBTitle: crystal structure of ruma, the iron-sulfur cluster2 containing e. coli 23s ribosomal rna 5-methyluridine3 methyltransferase
50d2esra1



not modelled 97.8 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
51d1wxxa2



not modelled 97.8 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
52d1l3ia_



not modelled 97.8 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Precorrin-6Y methyltransferase (CbiT)
53c2as0A_



not modelled 97.7 25 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ph1915;
PDBTitle: crystal structure of ph1915 (apc 5817): a hypothetical rna2 methyltransferase
54c3fydA_



not modelled 97.7 14 PDB header:transferase
Chain: A: PDB Molecule:probable dimethyladenosine transferase;
PDBTitle: crystal structure of dim1 from the thermophilic archeon,2 methanocaldococcus jannaschi
55d1zq9a1



not modelled 97.7 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA adenine dimethylase-like
56d2b78a2



not modelled 97.7 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
57c3grrA_



not modelled 97.7 14 PDB header:transferase
Chain: A: PDB Molecule:dimethyladenosine transferase;
PDBTitle: crystal structure of the complex between s-adenosyl homocysteine and2 methanocaldococcus jannaschi dim1.
58c3e05B_



not modelled 97.7 17 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y c5,15-methyltransferase (decarboxylating);
PDBTitle: crystal structure of precorrin-6y c5,15-methyltransferase from2 geobacter metallireducens gs-15
59d1yzha1



not modelled 97.7 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TrmB-like
60d1o9ga_



not modelled 97.7 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA methyltransferase AviRa
61c1m6yA_



not modelled 97.7 22 PDB header:transferase
Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw;
PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah
62c1wxwA_



not modelled 97.6 14 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha1280;
PDBTitle: crystal structure of tt1595, a putative sam-dependent2 methyltransferase from thermus thermophillus hb8
63c3fuxB_



not modelled 97.6 21 PDB header:transferase
Chain: B: PDB Molecule:dimethyladenosine transferase;
PDBTitle: t. thermophilus 16s rrna a1518 and a1519 methyltransferase (ksga) in2 complex with 5'-methylthioadenosine in space group p212121
64c2yxdA_



not modelled 97.6 20 PDB header:transferase
Chain: A: PDB Molecule:probable cobalt-precorrin-6y c(15)-methyltransferase
PDBTitle: crystal structure of cobalamin biosynthesis precorrin 8w decarboxylase2 (cbit)
65c2b78A_



not modelled 97.6 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein smu.776;
PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans
66d1pjza_



not modelled 97.6 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Thiopurine S-methyltransferase
67c3gnlB_



not modelled 97.6 9 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein, duf633, lmof2365_1472;
PDBTitle: structure of uncharacterized protein (lmof2365_1472) from2 listeria monocytogenes serotype 4b
68c3lecA_



not modelled 97.6 15 PDB header:structure genomics, unknown function
Chain: A: PDB Molecule:nadb-rossmann superfamily protein;
PDBTitle: the crystal structure of a protein in the nadb-rossmann2 superfamily from streptococcus agalactiae to 1.8a
69c3c0kB_



not modelled 97.6 9 PDB header:transferase
Chain: B: PDB Molecule:upf0064 protein yccw;
PDBTitle: crystal structure of a ribosomal rna methyltranferase
70c3evzA_



not modelled 97.6 15 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: crystal strucure of methyltransferase from pyrococcus furiosus
71c3g5tA_



not modelled 97.6 20 PDB header:transferase
Chain: A: PDB Molecule:trans-aconitate 3-methyltransferase;
PDBTitle: crystal structure of trans-aconitate 3-methyltransferase2 from yeast
72d1xj5a_



not modelled 97.5 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Spermidine synthase
73c3tqsB_



not modelled 97.5 13 PDB header:transferase
Chain: B: PDB Molecule:ribosomal rna small subunit methyltransferase a;
PDBTitle: structure of the dimethyladenosine transferase (ksga) from coxiella2 burnetii
74c3dmgA_



not modelled 97.5 19 PDB header:transferase
Chain: A: PDB Molecule:probable ribosomal rna small subunit methyltransferase;
PDBTitle: t. thermophilus 16s rrna n2 g1207 methyltransferase (rsmc) in complex2 with adohcy
75d1qyra_



not modelled 97.5 9 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA adenine dimethylase-like
76c3c6kC_



not modelled 97.5 13 PDB header:transferase
Chain: C: PDB Molecule:spermine synthase;
PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine
77d1o54a_



not modelled 97.5 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
78c2q41D_



not modelled 97.4 23 PDB header:transferase
Chain: D: PDB Molecule:spermidine synthase 1;
PDBTitle: ensemble refinement of the protein crystal structure of spermidine2 synthase from arabidopsis thaliana gene at1g23820
79c2h1rA_



not modelled 97.4 28 PDB header:transferase
Chain: A: PDB Molecule:dimethyladenosine transferase, putative;
PDBTitle: crystal structure of a dimethyladenosine transferase from2 plasmodium falciparum
80c2pwyB_



not modelled 97.4 23 PDB header:transferase
Chain: B: PDB Molecule:trna (adenine-n(1)-)-methyltransferase;
PDBTitle: crystal structure of a m1a58 trna methyltransferase
81d2igta1



not modelled 97.4 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
82d2fcaa1



not modelled 97.4 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TrmB-like
83d2b25a1



not modelled 97.4 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
84c3m33B_



not modelled 97.4 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of a functionally unknown protein from2 deinococcus radiodurans r1
85c2pjdA_



not modelled 97.4 20 PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase c;
PDBTitle: crystal structure of 16s rrna methyltransferase rsmc
86c3ku1E_



not modelled 97.3 13 PDB header:transferase
Chain: E: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine
87c3cggB_



not modelled 97.3 22 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of tehb-like sam-dependent methyltransferase2 (np_600671.1) from corynebacterium glutamicum atcc 13032 kitasato at3 2.00 a resolution
88c3a4tA_



not modelled 97.3 15 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase mj0026;
PDBTitle: crystal structure of atrm4 from m.jannaschii with sinefungin
89c3bxoA_



not modelled 97.3 13 PDB header:transferase
Chain: A: PDB Molecule:n,n-dimethyltransferase;
PDBTitle: crystal structure of streptomyces venezuelae desvi
90c2fk8A_



not modelled 97.2 19 PDB header:transferase
Chain: A: PDB Molecule:methoxy mycolic acid synthase 4;
PDBTitle: crystal structure of hma (mmaa4) from mycobacterium tuberculosis2 complexed with s-adenosylmethionine
91c2ozvA_



not modelled 97.2 20 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein atu0636;
PDBTitle: crystal structure of a predicted o-methyltransferase, protein atu6362 from agrobacterium tumefaciens.
92c3bwbA_



not modelled 97.2 24 PDB header:transferase
Chain: A: PDB Molecule:spermidine synthase;
PDBTitle: crystal structure of the apo form of spermidine synthase from2 trypanosoma cruzi at 2.5 a resolution
93d1i9ga_



not modelled 97.2 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
94d2h00a1



not modelled 97.2 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Methyltransferase 10 domain
95d1l1ea_



not modelled 97.1 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
96d1kpia_



not modelled 97.1 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
97c3bgvC_



not modelled 97.1 16 PDB header:transferase
Chain: C: PDB Molecule:mrna cap guanine-n7 methyltransferase;
PDBTitle: crystal structure of mrna cap guanine-n7 methyltransferase2 in complex with sah
98c3lccA_



not modelled 97.1 16 PDB header:transferase
Chain: A: PDB Molecule:putative methyl chloride transferase;
PDBTitle: structure of a sam-dependent halide methyltransferase from arabidopsis2 thaliana
99c3hm2G_



not modelled 97.1 16 PDB header:transferase
Chain: G: PDB Molecule:precorrin-6y c5,15-methyltransferase;
PDBTitle: crystal structure of putative precorrin-6y c5,15-2 methyltransferase targeted domain from corynebacterium3 diphtheriae
100d1ri5a_



not modelled 97.1 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:mRNA cap (Guanine N-7) methyltransferase
101c3q87B_



not modelled 97.1 12 PDB header:transferase activator/transferase
Chain: B: PDB Molecule:n6 adenine specific dna methylase;
PDBTitle: structure of eukaryotic translation termination complex2 methyltransferase mtq2-trm112
102c1z3cA_



not modelled 97.1 22 PDB header:transferase
Chain: A: PDB Molecule:mrna capping enzyme;
PDBTitle: encephalitozooan cuniculi mrna cap (guanine-n7)2 methyltransferasein complexed with azoadomet
103c3ll7A_



not modelled 97.1 20 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of putative methyltransferase pg_1098 from2 porphyromonas gingivalis w83
104d2b9ea1



not modelled 97.1 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
105d2bzga1



not modelled 97.0 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Thiopurine S-methyltransferase
106d1i1na_



not modelled 97.0 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
107c3mb5A_



not modelled 97.0 18 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of p. abyssi trna m1a58 methyltransferase in complex2 with s-adenosyl-l-methionine
108d1wzna1



not modelled 97.0 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:CAC2371-like
109c3bgdB_



not modelled 97.0 21 PDB header:transferase
Chain: B: PDB Molecule:thiopurine s-methyltransferase;
PDBTitle: thiopurine s-methyltransferase
110c1yb2A_



not modelled 97.0 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ta0852;
PDBTitle: structure of a putative methyltransferase from thermoplasma2 acidophilum.
111d1yb2a1



not modelled 97.0 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
112d1zx0a1



not modelled 97.0 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
113c3e23A_



not modelled 97.0 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein rpa2492;
PDBTitle: crystal structure of the rpa2492 protein in complex with2 sam from rhodopseudomonas palustris, northeast structural3 genomics consortium target rpr299
114d1nt2a_



not modelled 97.0 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
115c3gjyA_



not modelled 97.0 19 PDB header:transferase
Chain: A: PDB Molecule:spermidine synthase;
PDBTitle: crystal structure of a probable spermidine synthase from2 corynebacterium glutamicum atcc 13032
116d2fk8a1



not modelled 97.0 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
117d1sqga2



not modelled 96.9 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
118d1kpga_



not modelled 96.9 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
119c3g2qA_



not modelled 96.9 14 PDB header:transferase
Chain: A: PDB Molecule:pcza361.24;
PDBTitle: crystal structure of the glycopeptide n-methyltransferase mtfa2 complexed with sinefungin
120c2hteB_



not modelled 96.9 20 PDB header:transferase
Chain: B: PDB Molecule:spermidine synthase;
PDBTitle: the crystal structure of spermidine synthase from p. falciparum in2 complex with 5'-methylthioadenosine

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0