Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	L	V	D	S	H	C	H	L	D	G	L	D	Y	E	S	L	H	K	D	V	D	D	V	L	A	K	A	A	A	R	D	V	K	F	C	L	A	V	A	T	T	L	P	G	Y	L	H	M	R	D	L	V	G	E	R	D	N	V
Secondary structure
SS confidence
Disorder		?	?														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	F	S	C	G	V	H	P	L	N	Q	N	D	P	Y	D	V	E	D	L	R	R	L	A	A	E	E	G	V	V	A	L	G	E	T	G	L	D	Y	Y	Y	T	P	E	T	K	V	R	Q	Q	E	S	F	I	H	H	I	Q	I	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	E	L	N	K	P	V	I	V	H	T	R	D	A	R	A	D	T	L	A	I	L	R	E	E	K	V	T	D	C	G	G	V	L	H	C	F	T	E	D	R	E	T	A	G	K	L	L	D	L	G	F	Y	I	S	F	S	G	I	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	F	R	N	A	E	Q	L	R	D	A	A	R	Y	V	P	L	D	R	L	L	V	E	T	D	S	P	Y	L	A	P	V	P	H	R	G	K	E	N	Q	P	A	M	V	R	D	V	A	E	Y	M	A	V	L	K	G	V	A	V	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.
Sequence		E	L	A	Q	V	T	T	D	N	F	A	R	L	F	H	I	D	A	S	R	L	Q	S	I	R
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1yix chain A domain 1 Region: 1 - 265 Aligned: 265 Modelled: 265 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 1j6o chain A Region: 3 - 255 Aligned: 250 Modelled: 252 Confidence: 100.0% Identity: 35% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 1xwy chain A domain 1 Region: 3 - 256 Aligned: 251 Modelled: 254 Confidence: 100.0% Identity: 33% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 3rcm chain A Region: 2 - 260 Aligned: 256 Modelled: 256 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida Phyre2 PDB 2gzx chain B Region: 3 - 255 Aligned: 250 Modelled: 253 Confidence: 100.0% Identity: 38% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. Phyre2 PDB 2xio chain A Region: 1 - 255 Aligned: 253 Modelled: 255 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a Phyre2 PDB 1zzm chain A domain 1 Region: 1 - 257 Aligned: 253 Modelled: 257 Confidence: 100.0% Identity: 28% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 3ipw chain A Region: 1 - 254 Aligned: 252 Modelled: 254 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica Phyre2 PDB 2y1h chain A Region: 1 - 255 Aligned: 246 Modelled: 255 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) Phyre2 PDB 3e2v chain A Region: 1 - 255 Aligned: 255 Modelled: 255 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae Phyre2 PDB 3gg7 chain A Region: 3 - 255 Aligned: 239 Modelled: 249 Confidence: 100.0% Identity: 24% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized metalloprotein; PDBTitle: crystal structure of an uncharacterized metalloprotein from2 deinococcus radiodurans Phyre2 PDB 2ffi chain A domain 1 Region: 1 - 257 Aligned: 239 Modelled: 257 Confidence: 100.0% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 3irs chain B Region: 1 - 256 Aligned: 235 Modelled: 243 Confidence: 100.0% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica Phyre2 PDB 2wm1 chain A Region: 2 - 257 Aligned: 237 Modelled: 244 Confidence: 100.0% Identity: 17% PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis Phyre2 PDB 3ij6 chain A Region: 1 - 255 Aligned: 237 Modelled: 246 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from lactobacillus acidophilus Phyre2 PDB 2f6k chain A domain 1 Region: 4 - 255 Aligned: 232 Modelled: 235 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 2gwg chain A domain 1 Region: 3 - 258 Aligned: 253 Modelled: 256 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 3guw chain B Region: 3 - 256 Aligned: 213 Modelled: 238 Confidence: 100.0% Identity: 24% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 Phyre2 PDB 2hbv chain A domain 1 Region: 3 - 257 Aligned: 235 Modelled: 242 Confidence: 100.0% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 2dvt chain A domain 1 Region: 3 - 257 Aligned: 239 Modelled: 241 Confidence: 100.0% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 1 d1yixa1 2 d1j6oa_ 3 d1xwya1 4 c3rcmA_ 5 c2gzxB_ 6 c2xioA_ 7 d1zzma1 8 c3ipwA_ 9 c2y1hA_ 10 c3e2vA_ 11 c3gg7A_ 12 d2ffia1 13 c3irsB_ 14 c2wm1A_ 15 c3ij6A_ 16 d2f6ka1 17 d2gwga1 18 c3guwB_ 19 d2hbva1 20 d2dvta1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1yixa1 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 2 d1j6oa_ 100.0 35 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 3 d1xwya1 100.0 33 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 4 c3rcmA_ 100.0 28 PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida 5 c2gzxB_ 100.0 38 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. 6 c2xioA_ 100.0 26 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a 7 d1zzma1 100.0 28 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 8 c3ipwA_ 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica 9 c2y1hA_ 100.0 33 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) 10 c3e2vA_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae 11 c3gg7A_ 100.0 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized metalloprotein; PDBTitle: crystal structure of an uncharacterized metalloprotein from2 deinococcus radiodurans 12 d2ffia1 100.0 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 13 c3irsB_ 100.0 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica 14 c2wm1A_ 100.0 17 PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis 15 c3ij6A_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from lactobacillus acidophilus 16 d2f6ka1 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 17 d2gwga1 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 18 c3guwB_ 100.0 24 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 19 d2hbva1 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 20 d2dvta1 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 21 c3cjpA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:predicted amidohydrolase, dihydroorotase family; PDBTitle: crystal structure of an uncharacterized amidohydrolase cac3332 from2 clostridium acetobutylicum 22 c2qahA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:2-pyrone-4,6-dicarboxylic acid hydrolase; PDBTitle: crystal structure of the 2-pyrone-4,6-dicarboxylic acid2 hydrolase from sphingomonas paucimobilis 23 c3nurA_ not modelled 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus 24 d1bf6a_ not modelled 100.0 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 25 c3f4cA_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound 26 c2vc7A_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:aryldialkylphosphatase; PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities 27 d2d2ja1 not modelled 99.9 21 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 28 c3pnzD_ not modelled 99.9 16 PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes 29 d1i0da_ not modelled 99.9 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 30 c1pscA_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: phosphotriesterase from pseudomonas diminuta 31 c2zc1A_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: organophosphorus hydrolase from deinococcus radiodurans 32 c3k2gA_ not modelled 99.8 16 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 33 c3rhgA_ not modelled 99.8 17 PDB header:hydrolase Chain: A: PDB Molecule:putative phophotriesterase; PDBTitle: crystal structure of amidohydrolase pmi1525 (target efi-500319) from2 proteus mirabilis hi4320 34 d1xrta2 not modelled 99.8 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 35 c3msrA_ not modelled 99.6 13 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolases; PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae 36 c2qpxA_ not modelled 99.6 14 PDB header:hydrolase Chain: A: PDB Molecule:predicted metal-dependent hydrolase of the tim-barrel fold; PDBTitle: crystal structure of putative metal-dependent hydrolase (yp_805737.1)2 from lactobacillus casei atcc 334 at 1.40 a resolution 37 c3pnuA_ not modelled 99.6 16 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni. 38 d1nfga2 not modelled 99.6 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 39 d1k1da2 not modelled 99.6 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 40 d1ynya2 not modelled 99.5 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 41 d1gkra2 not modelled 99.5 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 42 c3nqbB_ not modelled 99.5 16 PDB header:hydrolase Chain: B: PDB Molecule:adenine deaminase 2; PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58) 43 d2ftwa2 not modelled 99.5 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 44 c1xrfA_ not modelled 99.5 12 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution 45 d2eg6a1 not modelled 99.5 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Dihydroorotase 46 d1gkpa2 not modelled 99.4 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 47 d2fvka2 not modelled 99.4 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 48 d2uz9a2 not modelled 99.4 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 49 d2icsa2 not modelled 99.4 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenine deaminase-like 50 d1kcxa2 not modelled 99.4 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 51 d1onwa2 not modelled 99.4 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Isoaspartyl dipeptidase, catalytic domain 52 c3jzeC_ not modelled 99.4 15 PDB header:hydrolase Chain: C: PDB Molecule:dihydroorotase; PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2 53 c2vunC_ not modelled 99.4 14 PDB header:hydrolase Chain: C: PDB Molecule:enamidase; PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily 54 d2paja2 not modelled 99.3 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 55 d2imra2 not modelled 99.3 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:DR0824-like 56 d2i9ua2 not modelled 99.3 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 57 d1p1ma2 not modelled 99.3 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 58 c3e0lB_ not modelled 99.3 12 PDB header:hydrolase Chain: B: PDB Molecule:guanine deaminase; PDBTitle: computationally designed ammelide deaminase 59 d3be7a2 not modelled 99.3 21 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 60 d1yrra2 not modelled 99.2 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 61 d2r8ca2 not modelled 99.2 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 62 d2p9ba2 not modelled 99.2 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 63 d2qs8a2 not modelled 99.2 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 64 d2bb0a2 not modelled 99.2 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 65 c3hpaB_ not modelled 99.2 11 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea 66 c1p1mA_ not modelled 99.2 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tm0936; PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine 67 c2pajA_ not modelled 99.1 12 PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/guanine deaminase; PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea 68 c2ogjB_ not modelled 99.1 16 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of a dihydroorotase 69 c2imrA_ not modelled 99.1 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dr_0824; PDBTitle: crystal structure of amidohydrolase dr_0824 from2 deinococcus radiodurans 70 c2i9uA_ not modelled 99.1 10 PDB header:hydrolase Chain: A: PDB Molecule:cytosine/guanine deaminase related protein; PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site 71 d1un7a2 not modelled 99.1 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 72 c2q09A_ not modelled 99.1 13 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid 73 d1ra0a2 not modelled 99.1 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Cytosine deaminase catalytic domain 74 d1itua_ not modelled 99.1 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Renal dipeptidase 75 c2aqoB_ not modelled 99.0 11 PDB header:hydrolase Chain: B: PDB Molecule:isoaspartyl dipeptidase; PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q 76 d2ooda2 not modelled 99.0 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 77 c2i5gB_ not modelled 99.0 12 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal strcuture of amidohydrolase from pseudomonas2 aeruginosa 78 c2bb0A_ not modelled 99.0 16 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: structure of imidazolonepropionase from bacillus subtilis 79 c3lnpA_ not modelled 99.0 13 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465; PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica 80 c3dc8B_ not modelled 99.0 15 PDB header:hydrolase Chain: B: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti 81 c1r9yA_ not modelled 99.0 15 PDB header:hydrolase Chain: A: PDB Molecule:cytosine deaminase; PDBTitle: bacterial cytosine deaminase d314a mutant. 82 c3gnhA_ not modelled 99.0 17 PDB header:hydrolase Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672; PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine. 83 c2gokA_ not modelled 98.9 14 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution 84 c1gkpD_ not modelled 98.9 17 PDB header:hydrolase Chain: D: PDB Molecule:hydantoinase; PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221 85 d2q09a2 not modelled 98.9 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 86 c3b40A_ not modelled 98.9 15 PDB header:hydrolase Chain: A: PDB Molecule:probable dipeptidase; PDBTitle: crystal structure of the probable dipeptidase pvdm from2 pseudomonas aeruginosa 87 c1k1dF_ not modelled 98.9 15 PDB header:hydrolase Chain: F: PDB Molecule:d-hydantoinase; PDBTitle: crystal structure of d-hydantoinase 88 d2puza2 not modelled 98.9 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 89 c3hm7A_ not modelled 98.9 14 PDB header:hydrolase Chain: A: PDB Molecule:allantoinase; PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125 90 c2icsA_ not modelled 98.9 15 PDB header:hydrolase Chain: A: PDB Molecule:adenine deaminase; PDBTitle: crystal structure of an adenine deaminase 91 c1gkrA_ not modelled 98.9 17 PDB header:hydrolase Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase; PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens 92 c3d6nA_ not modelled 98.8 13 PDB header:hydrolase/transferase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 93 c2vr2A_ not modelled 98.8 13 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase 94 c2ftwA_ not modelled 98.8 16 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase; PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum 95 c3lsbA_ not modelled 98.8 14 PDB header:hydrolase Chain: A: PDB Molecule:triazine hydrolase; PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin 96 d1o12a2 not modelled 98.8 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 97 c1nfgA_ not modelled 98.8 8 PDB header:hydrolase Chain: A: PDB Molecule:d-hydantoinase; PDBTitle: structure of d-hydantoinase 98 d4ubpc2 not modelled 98.8 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain 99 c2gseC_ not modelled 98.8 12 PDB header:hydrolase Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2; PDBTitle: crystal structure of human dihydropyrimidinease-like 2 100 c2p50C_ not modelled 98.7 11 PDB header:hydrolase Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn 101 c3ighX_ not modelled 98.7 22 PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus horikoshii ot3 102 c3etkA_ not modelled 98.7 22 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus furiosus 103 c2qt3A_ not modelled 98.7 13 PDB header:hydrolase Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase; PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn 104 c3mduA_ not modelled 98.7 13 PDB header:hydrolase Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase; PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate 105 c2fvmA_ not modelled 98.7 13 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine 106 c3fdgA_ not modelled 98.6 13 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidase ac. metallo peptidase. merops family m19; PDBTitle: the crystal structure of the dipeptidase ac, metallo peptidase. merops2 family m19 107 c2oodA_ not modelled 98.6 14 PDB header:hydrolase Chain: A: PDB Molecule:blr3880 protein; PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum 108 c3itcA_ not modelled 98.5 16 PDB header:hydrolase Chain: A: PDB Molecule:renal dipeptidase; PDBTitle: crystal structure of sco3058 with bound citrate and glycerol 109 c2ragB_ not modelled 98.5 11 PDB header:hydrolase Chain: B: PDB Molecule:dipeptidase; PDBTitle: crystal structure of aminohydrolase from caulobacter crescentus 110 c3lu2B_ not modelled 98.5 13 PDB header:hydrolase Chain: B: PDB Molecule:lmo2462 protein; PDBTitle: structure of lmo2462, a listeria monocytogenes amidohydrolase family2 putative dipeptidase 111 c2z00A_ not modelled 98.5 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of dihydroorotase from thermus thermophilus 112 c3be7B_ not modelled 98.5 20 PDB header:hydrolase Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase; PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase 113 c2p9bA_ not modelled 98.5 14 PDB header:hydrolase Chain: A: PDB Molecule:possible prolidase; PDBTitle: crystal structure of putative prolidase from2 bifidobacterium longum 114 c3mpgB_ not modelled 98.4 15 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: dihydroorotase from bacillus anthracis 115 d1m7ja3 not modelled 98.4 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:D-aminoacylase, catalytic domain 116 c3griB_ not modelled 98.4 10 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a dihydroorotase from staphylococcus aureus 117 c3e74D_ not modelled 98.3 13 PDB header:hydrolase Chain: D: PDB Molecule:allantoinase; PDBTitle: crystal structure of e. coli allantoinase with iron ions at2 the metal center 118 c2qs8A_ not modelled 98.3 17 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of a xaa-pro dipeptidase with bound2 methionine in the active site 119 c3la4A_ not modelled 98.3 13 PDB header:hydrolase Chain: A: PDB Molecule:urease; PDBTitle: crystal structure of the first plant urease from jack bean (canavalia2 ensiformis) 120 d1j5sa_ not modelled 98.3 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Uronate isomerase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0