PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1xrfA_

Fold library id	PDB Header	Molecule	Title
c1xrfA_	PDB header: hydrolase	Chain: A: PDB Molecule: dihydroorotase;	PDBTitle: the crystal structure of a novel, latent dihydroorotase2 from aquifex aeolicus at 1.7 a resolution

Links to external resources
Added to library: Tue Mar 16 12:29:17 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence W M L K L I V K N G Y V I D P S Q N L E G E F D I L V E N G K I K K I D K N I L V P E A E I I D A K G L I V C P G F I D I H V H L R D P G Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
G G G T
T T S S
S S
T T
T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence T Y K E D I E S G S R C A V A G G F T T I V C M P N T N P P I D N T T V V N Y I L Q K S K S V G L C R V L P T G T I T K G R K G K E I A D F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T T
S
S S S
S
S
S S
B
S B G G G
S S S B

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence Y S L K E A G C V A F T D D G S P V M D S S V M R K A L E L A S Q L G V P I M D H A E E I Q I A R D G I L A Q R T G G H V H I Q H V S T K L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
B
T T S
T
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence S L E I I E F F K E K G V K I T C E V N P N H L L D R L A L I E G V K R G I I D C F A T D H A P H Q T M P G I I G L Q T A L P S A L E L Y R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
G G G G
T
B
B
G G G

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence K G I I S L K K L I E M F T I N P A R I I G V D L G T L K L G S P A D I T I F D P N K E W I L N E E T N L S K S R N T P L W G K V L K G K V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S S
T T T
S
S
T T S B
S T T T
S S
T T T T

. . . . . . . . . 360 . . .

Sequence I Y T I K D G K M V Y K D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	W	M	L	K	L	I	V	K	N	G	Y	V	I	D	P	S	Q	N	L	E	G	E	F	D	I	L	V	E	N	G	K	I	K	K	I	D	K	N	I	L	V	P	E	A	E	I	I	D	A	K	G	L	I	V	C	P	G	F	I	D	I	H	V	H	L	R	D	P	G	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									S						G	G	G	T											T	T							S	S				S	S							T	T																T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	T	Y	K	E	D	I	E	S	G	S	R	C	A	V	A	G	G	F	T	T	I	V	C	M	P	N	T	N	P	P	I	D	N	T	T	V	V	N	Y	I	L	Q	K	S	K	S	V	G	L	C	R	V	L	P	T	G	T	I	T	K	G	R	K	G	K	E	I	A	D	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T													T	T								S		S	S	S		S		S																S	S						B		S	B	G	G	G		S	S	S	B
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	Y	S	L	K	E	A	G	C	V	A	F	T	D	D	G	S	P	V	M	D	S	S	V	M	R	K	A	L	E	L	A	S	Q	L	G	V	P	I	M	D	H	A	E	E	I	Q	I	A	R	D	G	I	L	A	Q	R	T	G	G	H	V	H	I	Q	H	V	S	T	K	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							T				B			T	T	S																			T																																	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	S	L	E	I	I	E	F	F	K	E	K	G	V	K	I	T	C	E	V	N	P	N	H	L	L	D	R	L	A	L	I	E	G	V	K	R	G	I	I	D	C	F	A	T	D	H	A	P	H	Q	T	M	P	G	I	I	G	L	Q	T	A	L	P	S	A	L	E	L	Y	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T									G	G	G	G													T									B									B			G	G	G
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	K	G	I	I	S	L	K	K	L	I	E	M	F	T	I	N	P	A	R	I	I	G	V	D	L	G	T	L	K	L	G	S	P	A	D	I	T	I	F	D	P	N	K	E	W	I	L	N	E	E	T	N	L	S	K	S	R	N	T	P	L	W	G	K	V	L	K	G	K	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	S	S										T							T	T		S		S				T	T	S	B															S	T	T	T			S	S					T	T	T	T
	.	.	.	.	.	.	.	.	.	360	.	.	.
Sequence	I	Y	T	I	K	D	G	K	M	V	Y	K	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T