Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		R	T	P	E	M	P	V	L	E	N	R	A	A	Q	G	D	I	T	A	P	G	G	A	R	R	L	T	G	D	Q	T	A	A	L	R	D	S	L	S	D	K	P	A	K	N	I	I	L	L	I	G	D	G	M	G	D	S	E	I	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?					?			?	?					?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	A	R	N	Y	A	E	G	A	G	G	F	F	K	G	I	D	A	L	P	L	T	G	Q	Y	T	H	Y	A	L	N	K	K	T	G	K	P	D	Y	V	T	D	S	A	A	S	A	T	A	W	S	T	G	V	K	T	Y	N	G	A
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?	?											?						?	?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	G	V	D	I	H	E	K	D	H	P	T	I	L	E	M	A	K	A	A	G	L	A	T	G	N	V	S	T	A	E	L	Q	D	A	T	P	A	A	L	E	A	H	V	T	S	R	K	C	Y	G	P	S	A	T	S	E	K	C	P
Secondary structure
SS confidence
Disorder																																																										?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	N	A	L	E	K	G	G	K	G	S	I	T	E	Q	L	L	N	A	R	A	D	V	T	L	G	G	G	A	K	T	F	A	E	T	A	T	A	G	E	W	Q	G	K	T	L	R	E	Q	A	Q	A	R	G	Y	Q	L	V	S	D
Secondary structure
SS confidence
Disorder		?																																			?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	A	S	L	N	S	V	T	E	A	N	Q	Q	K	P	L	L	G	L	F	A	D	G	N	M	P	V	R	W	L	G	P	K	A	T	Y	H	G	N	I	D	K	P	A	V	T	C	T	P	N	P	Q	R	N	D	S	V	P	T	L
Secondary structure
SS confidence
Disorder								?																									?	?	?	?	?										?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	Q	M	T	D	K	A	I	E	L	L	S	K	N	E	K	G	F	F	L	Q	V	E	G	A	S	I	D	K	Q	D	H	A	A	N	P	C	G	Q	I	G	E	T	V	D	L	D	E	A	V	Q	R	A	L	E	F	A	K	K	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	N	T	L	V	I	V	T	A	D	H	A	H	A	S	Q	I	V	A	P	D	T	K	A	P	G	L	T	Q	A	L	N	T	K	D	G	A	V	M	V	M	S	Y	G	N	S	E	E	D	S	Q	E	H	T	G	S	Q	L	R	I
Secondary structure
SS confidence
Disorder																			?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?									?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450
Sequence		A	A	Y	G	P	H	A	A	N	V	V	G	L	T	D	Q	T	D	L	F	Y	T	M	K	A	A	L	G	L	K
Secondary structure
SS confidence
Disorder																													?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1y6v chain A domain 1 Region: 2 - 450 Aligned: 449 Modelled: 449 Confidence: 100.0% Identity: 100% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Alkaline phosphatase Phyre2 PDB 1k7h chain A Region: 26 - 449 Aligned: 395 Modelled: 400 Confidence: 100.0% Identity: 36% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Alkaline phosphatase Phyre2 PDB 1zed chain A domain 1 Region: 20 - 449 Aligned: 402 Modelled: 404 Confidence: 100.0% Identity: 33% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Alkaline phosphatase Phyre2 PDB 1ew2 chain A Region: 20 - 450 Aligned: 403 Modelled: 410 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase Phyre2 PDB 3e2d chain B Region: 41 - 447 Aligned: 368 Modelled: 373 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase Phyre2 PDB 2x98 chain A Region: 41 - 450 Aligned: 364 Modelled: 373 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase Phyre2 PDB 2w0y chain B Region: 41 - 450 Aligned: 364 Modelled: 369 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase Phyre2 PDB 3a52 chain A Region: 45 - 448 Aligned: 344 Modelled: 362 Confidence: 100.0% Identity: 36% PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. Phyre2 PDB 2iuc chain B Region: 41 - 449 Aligned: 337 Modelled: 367 Confidence: 100.0% Identity: 31% PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 Phyre2 PDB 3m8y chain C Region: 42 - 450 Aligned: 310 Modelled: 310 Confidence: 99.9% Identity: 20% PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation Phyre2 PDB 2i09 chain A Region: 41 - 450 Aligned: 334 Modelled: 341 Confidence: 99.9% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans Phyre2 PDB 3igz chain B Region: 262 - 450 Aligned: 174 Modelled: 176 Confidence: 99.7% Identity: 20% PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration Phyre2 PDB 1o98 chain A Region: 264 - 450 Aligned: 159 Modelled: 162 Confidence: 99.6% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate Phyre2 PDB 1o98 chain A domain 2 Region: 44 - 450 Aligned: 261 Modelled: 274 Confidence: 99.5% Identity: 21% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain Phyre2 PDB 1hdh chain A Region: 41 - 450 Aligned: 312 Modelled: 318 Confidence: 99.5% Identity: 19% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3ed4 chain A Region: 45 - 450 Aligned: 277 Modelled: 281 Confidence: 99.5% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli Phyre2 PDB 1auk chain A Region: 42 - 450 Aligned: 307 Modelled: 319 Confidence: 99.4% Identity: 20% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3q3q chain A Region: 35 - 450 Aligned: 339 Modelled: 338 Confidence: 99.4% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 Phyre2 PDB 1p49 chain A Region: 39 - 450 Aligned: 319 Modelled: 321 Confidence: 99.4% Identity: 20% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 2i09 chain A domain 1 Region: 44 - 450 Aligned: 263 Modelled: 264 Confidence: 99.3% Identity: 19% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: DeoB catalytic domain-like Phyre2 1 d1y6va1 2 d1k7ha_ 3 d1zeda1 4 c1ew2A_ 5 c3e2dB_ 6 c2x98A_ 7 c2w0yB_ 8 c3a52A_ 9 c2iucB_ 10 c3m8yC_ 11 c2i09A_ 12 c3igzB_ 13 c1o98A_ 14 d1o98a2 15 d1hdha_ 16 c3ed4A_ 17 d1auka_ 18 c3q3qA_ 19 d1p49a_ 20 d2i09a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1y6va1 100.0 100 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 2 d1k7ha_ 100.0 36 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 3 d1zeda1 100.0 33 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 4 c1ew2A_ 100.0 33 PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase 5 c3e2dB_ 100.0 33 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase 6 c2x98A_ 100.0 33 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 7 c2w0yB_ 100.0 33 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 8 c3a52A_ 100.0 36 PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. 9 c2iucB_ 100.0 31 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 10 c3m8yC_ 99.9 20 PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation 11 c2i09A_ 99.9 18 PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans 12 c3igzB_ 99.7 20 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 13 c1o98A_ 99.6 18 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 14 d1o98a2 99.5 21 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain 15 d1hdha_ 99.5 19 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 16 c3ed4A_ 99.5 22 PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli 17 d1auka_ 99.4 20 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 18 c3q3qA_ 99.4 21 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 19 d1p49a_ 99.4 20 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 20 d2i09a1 99.3 19 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:DeoB catalytic domain-like 21 c3lxqB_ not modelled 99.3 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a 22 c2vqrA_ not modelled 99.2 14 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily 23 c2w8dB_ not modelled 99.2 15 PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis 24 c2qzuA_ not modelled 99.2 14 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 25 c2w5tA_ not modelled 99.2 15 PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. 26 d1fsua_ not modelled 99.2 20 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 27 c2xrgA_ not modelled 99.2 22 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 28 c2xr9A_ not modelled 99.2 22 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 29 c3b5qB_ not modelled 99.1 19 PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution 30 c2zktB_ not modelled 98.9 20 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii 31 d1ei6a_ not modelled 98.5 23 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Phosphonoacetate hydrolase 32 c3szzA_ not modelled 98.5 18 PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate 33 c2gsoB_ not modelled 98.3 20 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate 34 c2d1gB_ not modelled 96.8 16 PDB header:hydrolase Chain: B: PDB Molecule:acid phosphatase; PDBTitle: structure of francisella tularensis acid phosphatase a (acpa) bound to2 orthovanadate 35 c3iddA_ not modelled 82.6 25 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 36 d1b4ub_ not modelled 72.9 23 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 37 d2ihta3 not modelled 36.9 16 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 38 d1j8fa_ not modelled 30.3 16 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 39 d1frfs_ not modelled 29.0 25 Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nickel-iron hydrogenase, small subunit 40 c2q1wC_ not modelled 29.0 13 PDB header:sugar binding protein Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase; PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+ 41 c1q14A_ not modelled 28.6 13 PDB header:hydrolase Chain: A: PDB Molecule:hst2 protein; PDBTitle: structure and autoregulation of the yeast hst2 homolog of sir2 42 c2pjuD_ not modelled 23.9 16 PDB header:transcription Chain: D: PDB Molecule:propionate catabolism operon regulatory protein; PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr 43 c2pr7A_ not modelled 21.4 32 PDB header:hydrolase Chain: A: PDB Molecule:haloacid dehalogenase/epoxide hydrolase family; PDBTitle: crystal structure of uncharacterized protein (np_599989.1) from2 corynebacterium glutamicum atcc 13032 kitasato at 1.44 a resolution 44 d2pjua1 not modelled 20.5 16 Fold:Chelatase-like Superfamily:PrpR receptor domain-like Family:PrpR receptor domain-like 45 d1wuis1 not modelled 20.4 29 Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nickel-iron hydrogenase, small subunit 46 c1h2aS_ not modelled 20.4 29 PDB header:oxidoreductase Chain: S: PDB Molecule:hydrogenase; PDBTitle: single crystals of hydrogenase from desulfovibrio vulgaris 47 c3bq9A_ not modelled 20.2 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted rossmann fold nucleotide-binding domain- PDBTitle: crystal structure of predicted nucleotide-binding protein from2 idiomarina baltica os145 48 d1e3da_ not modelled 19.3 29 Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nickel-iron hydrogenase, small subunit 49 d1u7pa_ not modelled 19.0 18 Fold:HAD-like Superfamily:HAD-like Family:Magnesium-dependent phosphatase-1, Mdp1 50 d1xjca_ not modelled 18.5 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 51 d1q1aa_ not modelled 18.2 16 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 52 c3glsC_ not modelled 17.0 8 PDB header:hydrolase Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3, PDBTitle: crystal structure of human sirt3 53 d2a84a1 not modelled 16.1 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 54 d1es9a_ not modelled 16.0 21 Fold:Flavodoxin-like Superfamily:SGNH hydrolase Family:Acetylhydrolase 55 c3p94A_ not modelled 15.7 17 PDB header:hydrolase Chain: A: PDB Molecule:gdsl-like lipase; PDBTitle: crystal structure of a gdsl-like lipase (bdi_0976) from2 parabacteroides distasonis atcc 8503 at 1.93 a resolution 56 c3t9qB_ not modelled 15.6 25 PDB header:hydrolase Chain: B: PDB Molecule:stage ii sporulation protein e; PDBTitle: structure of the phosphatase domain of the cell fate determinant2 spoiie from bacillus subtilis (mn presoaked) 57 d1j83a_ not modelled 15.0 26 Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like Family:Family 17 carbohydrate binding module, CBM17 58 c2wpnA_ not modelled 15.0 34 PDB header:oxidoreductase Chain: A: PDB Molecule:periplasmic [nifese] hydrogenase, small subunit; PDBTitle: structure of the oxidised, as-isolated nifese hydrogenase2 from d. vulgaris hildenborough 59 c3pu9A_ not modelled 14.6 29 PDB header:transferase Chain: A: PDB Molecule:protein serine/threonine phosphatase; PDBTitle: crystal structure of serine/threonine phosphatase sphaerobacter2 thermophilus dsm 20745 60 d1ghca_ not modelled 14.5 33 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Linker histone H1/H5 61 c3gvzB_ not modelled 14.1 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein cv2077; PDBTitle: crystal structure of the protein cv2077 from2 chromobacterium violaceum. northeast structural genomics3 consortium target cvr62 62 d1uhma_ not modelled 14.1 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Linker histone H1/H5 63 d1ozha3 not modelled 14.0 24 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 64 c3ibsA_ not modelled 14.0 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein batb; PDBTitle: crystal structure of conserved hypothetical protein batb from2 bacteroides thetaiotaomicron 65 d1t9ba3 not modelled 13.9 24 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 66 d1qh8a_ not modelled 13.6 6 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 67 d1p4da_ not modelled 13.4 23 Fold:Origin of replication-binding domain, RBD-like Superfamily:Origin of replication-binding domain, RBD-like Family:Relaxase domain 68 c3b3jA_ not modelled 13.3 31 PDB header:transferase Chain: A: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: the 2.55 a crystal structure of the apo catalytic domain of2 coactivator-associated arginine methyl transferase i(carm1:28-507,3 residues 28-146 and 479-507 not ordered) 69 c3u1hA_ not modelled 13.0 45 PDB header:oxidoreductase Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase; PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus 70 c2q5cA_ not modelled 12.8 11 PDB header:transcription Chain: A: PDB Molecule:ntrc family transcriptional regulator; PDBTitle: crystal structure of ntrc family transcriptional regulator from2 clostridium acetobutylicum 71 c2kjwA_ not modelled 12.8 38 PDB header:ribosomal protein Chain: A: PDB Molecule:30s ribosomal protein s6; PDBTitle: solution structure and backbone dynamics of the permutant2 p54-55 72 d2d0oa2 not modelled 12.7 29 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ATPase domain of dehydratase reactivase alpha subunit 73 d1fxwf_ not modelled 12.2 21 Fold:Flavodoxin-like Superfamily:SGNH hydrolase Family:Acetylhydrolase 74 c1z2iA_ not modelled 12.2 24 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium 75 d1qyia_ not modelled 12.1 23 Fold:HAD-like Superfamily:HAD-like Family:Hypothetical protein MW1667 (SA1546) 76 d1usta_ not modelled 12.0 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Linker histone H1/H5 77 d1hsta_ not modelled 12.0 37 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Linker histone H1/H5 78 c3uoeB_ not modelled 12.0 20 PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti 79 d1ek6a_ not modelled 11.9 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 80 c3enkB_ not modelled 11.8 25 PDB header:isomerase Chain: B: PDB Molecule:udp-glucose 4-epimerase; PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei 81 c3cdiA_ not modelled 11.8 19 PDB header:transferase Chain: A: PDB Molecule:polynucleotide phosphorylase; PDBTitle: crystal structure of e. coli pnpase 82 d1w0da_ not modelled 11.7 25 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 83 d1cc1s_ not modelled 11.7 38 Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nickel-iron hydrogenase, small subunit 84 c3rgwS_ not modelled 11.4 29 PDB header:oxidoreductase/oxidoreductase Chain: S: PDB Molecule:membrane-bound hydrogenase (nife) small subunit hoxk; PDBTitle: crystal structure at 1.5 a resolution of an h2-reduced, o2-tolerant2 hydrogenase from ralstonia eutropha unmasks a novel iron-sulfur3 cluster 85 d1lxna_ not modelled 11.3 26 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 86 d1dj0a_ not modelled 11.2 10 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase I TruA 87 c3bz6A_ not modelled 11.1 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0502 protein pspto_2686; PDBTitle: crystal structure of a conserved protein of unknown function from2 pseudomonas syringae pv. tomato str. dc3000 88 d1ussa_ not modelled 11.0 30 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Linker histone H1/H5 89 c1nl3B_ not modelled 10.8 14 PDB header:protein transport Chain: B: PDB Molecule:preprotein translocase seca 1 subunit; PDBTitle: crystal structure of the seca protein translocation atpase2 from mycobacterium tuberculosis in apo form 90 d1yqaa1 not modelled 10.6 30 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Linker histone H1/H5 91 c1t9dB_ not modelled 10.3 24 PDB header:transferase Chain: B: PDB Molecule:acetolactate synthase, mitochondrial; PDBTitle: crystal structure of yeast acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, metsulfuron methyl 92 d1tfra2 not modelled 10.2 18 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 93 d1pvda3 not modelled 10.1 62 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 94 c2odaB_ not modelled 10.1 9 PDB header:protein binding Chain: B: PDB Molecule:hypothetical protein pspto_2114; PDBTitle: crystal structure of pspto_2114 95 c2iueA_ not modelled 9.6 14 PDB header:membrane protein Chain: A: PDB Molecule:pactolus i-domain; PDBTitle: pactolus i-domain: functional switching of the rossmann2 fold 96 d1nxua_ not modelled 9.6 16 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 97 d1xrha_ not modelled 9.6 16 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 98 d1e3ha5 not modelled 9.3 10 Fold:Ribonuclease PH domain 2-like Superfamily:Ribonuclease PH domain 2-like Family:Ribonuclease PH domain 2-like 99 c3blxL_ not modelled 9.2 14 PDB header:oxidoreductase Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2; PDBTitle: yeast isocitrate dehydrogenase (apo form)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0