Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A6E4
DateThu Jan 5 11:02:56 GMT 2012
Unique Job ID129171b4babeed25

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1k97A_
Top template information
PDB header:ligase
Chain: A: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline
Confidence and coverage
Confidence:100.0% Coverage: 97%
432 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTANLGQPDEEDYDAIPRRA
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Disorder  ??



??
?

















































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   .........70.........80.........90.........100.........110.........120
Sequence  MEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNTTPLGRAVTGTMLVAAMKE
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   .........130.........140.........150.........160.........170.........180
Sequence  DGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDTDFIDELGGRHEMSEFMIACG
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???
?












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   .........190.........200.........210.........220.........230.........240
Sequence  FDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVNPIMGVKFWDESVKIPAEEVTVR
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Disorder 

?
??????
























?










?











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   .........250.........260.........270.........280.........290.........300
Sequence  FEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGMALL
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??













































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   .........310.........320.........330.........340.........350.........360
Sequence  HIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQGRWFDSQALMLRDSLQRWVASQITGEV
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   .........370.........380.........390.........400.........410.........420
Sequence  TLELRRGNDYSILNTVSENLTYKPERLTMEKGDSVFSPDDRIGQLTMRNLDITDTREKLF
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Disorder 












?

?????







??????
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   .........430.........440.......
Sequence  GYAKTGLLSSSAASGVPQVENLENKGQ
Secondary structure 


















SS confidence 


























Disorder  ?????
?????????????????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1k97 chain A

3D model

Region: 2 - 441
Aligned: 432
Modelled: 440
Confidence: 100.0%
Identity: 100%
PDB header:ligase
Chain: A: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline

Phyre2

PDB 1vl2 chain C

3D model

Region: 11 - 424
Aligned: 387
Modelled: 414
Confidence: 100.0%
Identity: 30%
PDB header:ligase
Chain: C: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution

Phyre2

PDB 1kh2 chain D

3D model

Region: 13 - 420
Aligned: 381
Modelled: 408
Confidence: 100.0%
Identity: 30%
PDB header:ligase
Chain: D: PDB Molecule:argininosuccinate synthetase;
PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp

Phyre2

PDB 2nz2 chain A

3D model

Region: 11 - 425
Aligned: 396
Modelled: 415
Confidence: 100.0%
Identity: 27%
PDB header:ligase
Chain: A: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline

Phyre2

PDB 1k92 chain A domain 2

3D model

Region: 190 - 445
Aligned: 256
Modelled: 256
Confidence: 100.0%
Identity: 100%
Fold: Argininosuccinate synthetase, C-terminal domain
Superfamily: Argininosuccinate synthetase, C-terminal domain
Family: Argininosuccinate synthetase, C-terminal domain

Phyre2

PDB 1j20 chain A domain 2

3D model

Region: 190 - 425
Aligned: 221
Modelled: 236
Confidence: 100.0%
Identity: 28%
Fold: Argininosuccinate synthetase, C-terminal domain
Superfamily: Argininosuccinate synthetase, C-terminal domain
Family: Argininosuccinate synthetase, C-terminal domain

Phyre2

PDB 1vl2 chain A domain 2

3D model

Region: 188 - 426
Aligned: 220
Modelled: 239
Confidence: 100.0%
Identity: 28%
Fold: Argininosuccinate synthetase, C-terminal domain
Superfamily: Argininosuccinate synthetase, C-terminal domain
Family: Argininosuccinate synthetase, C-terminal domain

Phyre2

PDB 1k92 chain A domain 1

3D model

Region: 2 - 189
Aligned: 188
Modelled: 188
Confidence: 100.0%
Identity: 100%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2

PDB 1vl2 chain A domain 1

3D model

Region: 11 - 183
Aligned: 165
Modelled: 173
Confidence: 100.0%
Identity: 32%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2

PDB 1j20 chain A domain 1

3D model

Region: 13 - 184
Aligned: 162
Modelled: 168
Confidence: 100.0%
Identity: 32%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2

PDB 3a2k chain B

3D model

Region: 8 - 189
Aligned: 163
Modelled: 164
Confidence: 100.0%
Identity: 15%
PDB header:ligase/rna
Chain: B: PDB Molecule:trna(ile)-lysidine synthase;
PDBTitle: crystal structure of tils complexed with trna

Phyre2

PDB 1ni5 chain A

3D model

Region: 6 - 189
Aligned: 159
Modelled: 164
Confidence: 100.0%
Identity: 16%
PDB header:cell cycle
Chain: A: PDB Molecule:putative cell cycle protein mesj;
PDBTitle: structure of the mesj pp-atpase from escherichia coli

Phyre2

PDB 2e21 chain A

3D model

Region: 6 - 189
Aligned: 165
Modelled: 168
Confidence: 99.9%
Identity: 16%
PDB header:ligase
Chain: A: PDB Molecule:trna(ile)-lysidine synthase;
PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus.

Phyre2

PDB 1ni5 chain A domain 1

3D model

Region: 3 - 189
Aligned: 162
Modelled: 164
Confidence: 99.9%
Identity: 17%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: PP-loop ATPase

Phyre2

PDB 1wy5 chain A domain 1

3D model

Region: 6 - 189
Aligned: 165
Modelled: 168
Confidence: 99.9%
Identity: 18%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: PP-loop ATPase

Phyre2

PDB 2hma chain A

3D model

Region: 9 - 189
Aligned: 168
Modelled: 174
Confidence: 99.9%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)-
PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae

Phyre2

PDB 2der chain A

3D model

Region: 12 - 182
Aligned: 165
Modelled: 171
Confidence: 99.9%
Identity: 12%
PDB header:transferase/rna
Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma;
PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state

Phyre2

PDB 2c5s chain A domain 1

3D model

Region: 10 - 196
Aligned: 167
Modelled: 185
Confidence: 99.8%
Identity: 14%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: ThiI-like

Phyre2

PDB 1gpm chain A domain 1

3D model

Region: 5 - 191
Aligned: 159
Modelled: 185
Confidence: 99.8%
Identity: 16%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Adenine nucleotide alpha hydrolases-like
Family: N-type ATP pyrophosphatases

Phyre2

PDB 3k32 chain D

3D model

Region: 14 - 198
Aligned: 162
Modelled: 174
Confidence: 99.8%
Identity: 20%
PDB header:transferase
Chain: D: PDB Molecule:uncharacterized protein mj0690;
PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm

Phyre2
1

c1k97A_
2

c1vl2C_
3

c1kh2D_
4

c2nz2A_
5

d1k92a2
6

d1j20a2
7

d1vl2a2
8

d1k92a1
9

d1vl2a1
10

d1j20a1
11

c3a2kB_
12

c1ni5A_
13

c2e21A_
14

d1ni5a1
15

d1wy5a1
16

c2hmaA_
17

c2derA_
18

d2c5sa1
19

d1gpma1
20

c3k32D_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1k97A_



100.0 100 PDB header:ligase
Chain: A: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline
2c1vl2C_



100.0 30 PDB header:ligase
Chain: C: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution
3c1kh2D_



100.0 30 PDB header:ligase
Chain: D: PDB Molecule:argininosuccinate synthetase;
PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp
4c2nz2A_



100.0 27 PDB header:ligase
Chain: A: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline
5d1k92a2



100.0 100 Fold:Argininosuccinate synthetase, C-terminal domain
Superfamily:Argininosuccinate synthetase, C-terminal domain
Family:Argininosuccinate synthetase, C-terminal domain
6d1j20a2



100.0 28 Fold:Argininosuccinate synthetase, C-terminal domain
Superfamily:Argininosuccinate synthetase, C-terminal domain
Family:Argininosuccinate synthetase, C-terminal domain
7d1vl2a2



100.0 28 Fold:Argininosuccinate synthetase, C-terminal domain
Superfamily:Argininosuccinate synthetase, C-terminal domain
Family:Argininosuccinate synthetase, C-terminal domain
8d1k92a1



100.0 100 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
9d1vl2a1



100.0 32 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
10d1j20a1



100.0 32 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
11c3a2kB_



100.0 15 PDB header:ligase/rna
Chain: B: PDB Molecule:trna(ile)-lysidine synthase;
PDBTitle: crystal structure of tils complexed with trna
12c1ni5A_



100.0 16 PDB header:cell cycle
Chain: A: PDB Molecule:putative cell cycle protein mesj;
PDBTitle: structure of the mesj pp-atpase from escherichia coli
13c2e21A_



99.9 16 PDB header:ligase
Chain: A: PDB Molecule:trna(ile)-lysidine synthase;
PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus.
14d1ni5a1



99.9 17 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:PP-loop ATPase
15d1wy5a1



99.9 18 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:PP-loop ATPase
16c2hmaA_



99.9 16 PDB header:transferase
Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)-
PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae
17c2derA_



99.9 12 PDB header:transferase/rna
Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma;
PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state
18d2c5sa1



99.8 14 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:ThiI-like
19d1gpma1



99.8 16 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
20c3k32D_



99.8 20 PDB header:transferase
Chain: D: PDB Molecule:uncharacterized protein mj0690;
PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm
21c2dplA_



not modelled 99.8 20 PDB header:ligase
Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b;
PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3
22c2c5sA_



not modelled 99.8 17 PDB header:rna-binding protein
Chain: A: PDB Molecule:probable thiamine biosynthesis protein thii;
PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain
23c3tqiB_



not modelled 99.8 14 PDB header:ligase
Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing];
PDBTitle: structure of the gmp synthase (guaa) from coxiella burnetii
24c3bl5E_



not modelled 99.7 18 PDB header:hydrolase
Chain: E: PDB Molecule:queuosine biosynthesis protein quec;
PDBTitle: crystal structure of quec from bacillus subtilis: an enzyme2 involved in preq1 biosynthesis
25c3p52B_



not modelled 99.7 12 PDB header:ligase
Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase;
PDBTitle: nh3-dependent nad synthetase from campylobacter jejuni subsp. jejuni2 nctc 11168 in complex with the nitrate ion
26d2pg3a1



not modelled 99.7 16 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
27c2ywcC_



not modelled 99.7 16 PDB header:ligase
Chain: C: PDB Molecule:gmp synthase [glutamine-hydrolyzing];
PDBTitle: crystal structure of gmp synthetase from thermus thermophilus in2 complex with xmp
28c3fiuD_



not modelled 99.7 15 PDB header:ligase
Chain: D: PDB Molecule:nh(3)-dependent nad(+) synthetase;
PDBTitle: structure of nmn synthetase from francisella tularensis
29c2vxoB_



not modelled 99.7 14 PDB header:ligase
Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing];
PDBTitle: human gmp synthetase in complex with xmp
30d1vbka1



not modelled 99.6 13 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:ThiI-like
31d1sura_



not modelled 99.6 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:PAPS reductase-like
32d1xnga1



not modelled 99.6 13 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
33c1gpmD_



not modelled 99.5 15 PDB header:transferase (glutamine amidotransferase)
Chain: D: PDB Molecule:gmp synthetase;
PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate
34c2o8vA_



not modelled 99.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoadenosine phosphosulfate reductase;
PDBTitle: paps reductase in a covalent complex with thioredoxin c35a
35c2e18B_



not modelled 99.5 18 PDB header:ligase
Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase;
PDBTitle: crystal structure of project ph0182 from pyrococcus horikoshii ot3
36c3uowB_



not modelled 99.5 14 PDB header:ligase
Chain: B: PDB Molecule:gmp synthetase;
PDBTitle: crystal structure of pf10_0123, a gmp synthetase from plasmodium2 falciparum
37d1ru8a_



not modelled 99.5 20 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
38c3q4gA_



not modelled 99.3 11 PDB header:ligase
Chain: A: PDB Molecule:nh(3)-dependent nad(+) synthetase;
PDBTitle: structure of nad synthetase from vibrio cholerae
39c2goyC_



not modelled 99.3 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:adenosine phosphosulfate reductase;
PDBTitle: crystal structure of assimilatory adenosine 5'-2 phosphosulfate reductase with bound aps
40d1zuna1



not modelled 99.3 9 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:PAPS reductase-like
41c3dpiA_



not modelled 99.3 15 PDB header:ligase
Chain: A: PDB Molecule:nad+ synthetase;
PDBTitle: crystal structure of nad+ synthetase from burkholderia pseudomallei
42c1zunA_



not modelled 99.2 10 PDB header:transferase
Chain: A: PDB Molecule:sulfate adenylyltransferase subunit 2;
PDBTitle: crystal structure of a gtp-regulated atp sulfurylase2 heterodimer from pseudomonas syringae
43d1kqpa_



not modelled 99.1 14 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
44c2oq2B_



not modelled 99.1 9 PDB header:oxidoreductase
Chain: B: PDB Molecule:phosphoadenosine phosphosulfate reductase;
PDBTitle: crystal structure of yeast paps reductase with pap, a product complex
45d1wxia1



not modelled 98.9 12 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
46d2d13a1



not modelled 98.9 20 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
47c1vbkA_



not modelled 98.8 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ph1313;
PDBTitle: crystal structure of ph1313 from pyrococcus horikoshii ot3
48c3g59A_



not modelled 98.7 12 PDB header:transferase
Chain: A: PDB Molecule:fmn adenylyltransferase;
PDBTitle: crystal structure of candida glabrata fmn2 adenylyltransferase in complex with atp
49c1ct9D_



not modelled 98.6 20 PDB header:ligase
Chain: D: PDB Molecule:asparagine synthetase b;
PDBTitle: crystal structure of asparagine synthetase b from2 escherichia coli
50d1q15a1



not modelled 98.6 17 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
51c3n05B_



not modelled 98.5 15 PDB header:ligase
Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase;
PDBTitle: crystal structure of nh3-dependent nad+ synthetase from streptomyces2 avermitilis
52d1ct9a1



not modelled 98.5 20 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
53d1jgta1



not modelled 98.5 12 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
54c2wsiA_



not modelled 98.3 13 PDB header:transferase
Chain: A: PDB Molecule:fad synthetase;
PDBTitle: crystal structure of yeast fad synthetase (fad1) in complex2 with fad
55c1q15A_



not modelled 98.2 18 PDB header:biosynthetic protein
Chain: A: PDB Molecule:cara;
PDBTitle: carbapenam synthetase
56c1m1zB_



not modelled 98.2 12 PDB header:hydrolase
Chain: B: PDB Molecule:beta-lactam synthetase;
PDBTitle: beta-lactam synthetase apo enzyme
57c3dlaD_



not modelled 97.8 17 PDB header:ligase
Chain: D: PDB Molecule:glutamine-dependent nad(+) synthetase;
PDBTitle: x-ray crystal structure of glutamine-dependent nad+ synthetase from2 mycobacterium tuberculosis bound to naad+ and don
58c3ilvA_



not modelled 97.6 13 PDB header:ligase
Chain: A: PDB Molecule:glutamine-dependent nad(+) synthetase;
PDBTitle: crystal structure of a glutamine-dependent nad(+) synthetase2 from cytophaga hutchinsonii
59d1tq8a_



not modelled 94.8 22 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:Universal stress protein-like
60c2vpqA_



not modelled 94.1 16 PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase;
PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp
61c3g8cB_



not modelled 93.0 15 PDB header:ligase
Chain: B: PDB Molecule:biotin carboxylase;
PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion
62c2gpwC_



not modelled 92.6 15 PDB header:ligase
Chain: C: PDB Molecule:biotin carboxylase;
PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli.
63c1ulzA_



not modelled 92.3 22 PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain;
PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase
64c2fmoA_



not modelled 92.1 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:5,10-methylenetetrahydrofolate reductase;
PDBTitle: ala177val mutant of e. coli methylenetetrahydrofolate2 reductase
65c3ouzA_



not modelled 91.5 12 PDB header:ligase
Chain: A: PDB Molecule:biotin carboxylase;
PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni
66c3u9sE_



not modelled 88.7 22 PDB header:ligase
Chain: E: PDB Molecule:methylcrotonyl-coa carboxylase, alpha-subunit;
PDBTitle: crystal structure of p. aeruginosa 3-methylcrotonyl-coa carboxylase2 (mcc) 750 kd holoenzyme, coa complex
67c3louB_



not modelled 86.3 16 PDB header:hydrolase
Chain: B: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of formyltetrahydrofolate deformylase (yp_105254.1)2 from burkholderia mallei atcc 23344 at 1.90 a resolution
68c3nbmA_



not modelled 84.5 10 PDB header:transferase
Chain: A: PDB Molecule:pts system, lactose-specific iibc components;
PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae.
69c2p88E_



not modelled 83.6 12 PDB header:lyase
Chain: E: PDB Molecule:mandelate racemase/muconate lactonizing enzyme
PDBTitle: crystal structure of n-succinyl arg/lys racemase from2 bacillus cereus atcc 14579
70c3q45E_



not modelled 83.5 13 PDB header:isomerase
Chain: E: PDB Molecule:mandelate racemase/muconate lactonizing enzyme family;
PDBTitle: crystal structure of dipeptide epimerase from cytophaga hutchinsonii2 complexed with mg and dipeptide d-ala-l-val
71c3fojA_



not modelled 83.4 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of ssp1007 from staphylococcus2 saprophyticus subsp. saprophyticus. northeast structural3 genomics target syr101a.
72c3mcuF_



not modelled 83.3 31 PDB header:oxidoreductase
Chain: F: PDB Molecule:dipicolinate synthase, b chain;
PDBTitle: crystal structure of the dipicolinate synthase chain b from2 bacillus cereus. northeast structural genomics consortium3 target bcr215.
73c3zquA_



not modelled 83.3 15 PDB header:lyase
Chain: A: PDB Molecule:probable aromatic acid decarboxylase;
PDBTitle: structure of a probable aromatic acid decarboxylase
74c3lqkA_



not modelled 82.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit b;
PDBTitle: crystal structure of dipicolinate synthase subunit b from bacillus2 halodurans c
75c3ddmD_



not modelled 82.7 16 PDB header:lyase
Chain: D: PDB Molecule:putative mandelate racemase/muconate lactonizing
PDBTitle: crystal structure of mandelate racemase/muconate2 lactonizing enzyme from bordetella bronchiseptica rb50
76c2dzdB_



not modelled 82.3 17 PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase
77d1b5ta_



not modelled 81.2 12 Fold:TIM beta/alpha-barrel
Superfamily:FAD-linked oxidoreductase
Family:Methylenetetrahydrofolate reductase
78c2l2qA_



not modelled 80.2 16 PDB header:transferase
Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela);
PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi
79c3n6rK_



not modelled 80.1 14 PDB header:ligase
Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit;
PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc)
80d1v93a_



not modelled 80.0 16 Fold:TIM beta/alpha-barrel
Superfamily:FAD-linked oxidoreductase
Family:Methylenetetrahydrofolate reductase
81c3px5A_



not modelled 79.1 11 PDB header:metal binding protein
Chain: A: PDB Molecule:enzyme of enolase superfamily;
PDBTitle: structure of efi enolase target en500555, a putative dipeptide2 epimerase: apo structure
82c2qdeA_



not modelled 78.7 10 PDB header:lyase
Chain: A: PDB Molecule:mandelate racemase/muconate lactonizing enzyme family
PDBTitle: crystal structure of mandelate racemase/muconate lactonizing family2 protein from azoarcus sp. ebn1
83c2pfsA_



not modelled 77.2 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:universal stress protein;
PDBTitle: crystal structure of universal stress protein from nitrosomonas2 europaea
84c1wv9B_



not modelled 76.8 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:rhodanese homolog tt1651;
PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8
85d1p3y1_



not modelled 76.7 14 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
86c3o1lB_



not modelled 76.5 7 PDB header:hydrolase
Chain: B: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution
87c3jw7E_



not modelled 76.2 13 PDB header:isomerase
Chain: E: PDB Molecule:dipeptide epimerase;
PDBTitle: crystal structure of dipeptide epimerase from enterococcus faecalis2 v583 complexed with mg and dipeptide l-ile-l-tyr
88c2xdqA_



not modelled 75.4 8 PDB header:oxidoreductase
Chain: A: PDB Molecule:light-independent protochlorophyllide reductase subunit n;
PDBTitle: dark operative protochlorophyllide oxidoreductase (chln-2 chlb)2 complex
89d1qzua_



not modelled 75.4 9 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
90d2z3va1



not modelled 74.1 17 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:Universal stress protein-like
91c3obiC_



not modelled 73.7 11 PDB header:hydrolase
Chain: C: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (np_949368)2 from rhodopseudomonas palustris cga009 at 1.95 a resolution
92d1vlia2



not modelled 72.4 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
93c1zrsB_



not modelled 72.0 12 PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: wild-type ld-carboxypeptidase
94d1iuka_



not modelled 71.0 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:CoA-binding domain
95c1jvnB_



not modelled 70.8 15 PDB header:transferase
Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf;
PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites
96d2auna2



not modelled 69.4 12 Fold:Flavodoxin-like
Superfamily:Class I glutamine amidotransferase-like
Family:LD-carboxypeptidase A N-terminal domain-like
97c3nrbD_



not modelled 69.1 12 PDB header:hydrolase
Chain: D: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (puru,2 pp_1943) from pseudomonas putida kt2440 at 2.05 a resolution
98d1q77a_



not modelled 69.0 14 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:Universal stress protein-like
99c1tvmA_



not modelled 68.6 13 PDB header:transferase
Chain: A: PDB Molecule:pts system, galactitol-specific iib component;
PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system
100c3hgmD_



not modelled 68.5 17 PDB header:signaling protein
Chain: D: PDB Molecule:universal stress protein tead;
PDBTitle: universal stress protein tead from the trap transporter2 teaabc of halomonas elongata
101c1yt8A_



not modelled 67.8 12 PDB header:transferase
Chain: A: PDB Molecule:thiosulfate sulfurtransferase;
PDBTitle: crystal structure of thiosulfate sulfurtransferase from pseudomonas2 aeruginosa
102d1iiba_



not modelled 67.2 22 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Lactose/Cellobiose specific IIB subunit
103c3n0vD_



not modelled 67.2 14 PDB header:hydrolase
Chain: D: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution
104c2ejbA_



not modelled 65.8 10 PDB header:lyase
Chain: A: PDB Molecule:probable aromatic acid decarboxylase;
PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus
105c3gdhC_



not modelled 64.8 15 PDB header:transferase
Chain: C: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form)
106c3mt0A_



not modelled 64.4 8 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein pa1789;
PDBTitle: the crystal structure of a functionally unknown protein pa1789 from2 pseudomonas aeruginosa pao1
107d1g5qa_



not modelled 64.3 6 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD
108c3o3nA_



not modelled 63.8 15 PDB header:lyase
Chain: A: PDB Molecule:alpha-subunit 2-hydroxyisocaproyl-coa dehydratase;
PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa
109c2jyaA_



not modelled 62.5 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein atu1810;
PDBTitle: nmr solution structure of protein atu1810 from agrobacterium2 tumefaciens. northeast structural genomics consortium target atr23,3 ontario centre for structural proteomics target atc1776
110d1qh8b_



not modelled 60.7 17 Fold:Chelatase-like
Superfamily:"Helical backbone" metal receptor
Family:Nitrogenase iron-molybdenum protein
111d2dx7a1



not modelled 60.5 15 Fold:ATC-like
Superfamily:Aspartate/glutamate racemase
Family:Aspartate/glutamate racemase
112c2iy3A_



not modelled 60.2 13 PDB header:rna-binding
Chain: A: PDB Molecule:signal recognition particle protein ffh;
PDBTitle: structure of the e. coli signal recognition particle2 bound to a translating ribosome
113c3sjnB_



not modelled 59.7 10 PDB header:lyase
Chain: B: PDB Molecule:mandelate racemase/muconate lactonizing protein;
PDBTitle: crystal structure of enolase spea_3858 (target efi-500646) from2 shewanella pealeana with magnesium bound
114d1sjda1



not modelled 59.3 11 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:D-glucarate dehydratase-like
115d2dfaa1



not modelled 59.0 18 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
116d2zdra2



not modelled 57.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
117c2qk4A_



not modelled 57.8 21 PDB header:ligase
Chain: A: PDB Molecule:trifunctional purine biosynthetic protein adenosine-3;
PDBTitle: human glycinamide ribonucleotide synthetase
118c1jpmB_



not modelled 57.5 11 PDB header:isomerase
Chain: B: PDB Molecule:l-ala-d/l-glu epimerase;
PDBTitle: l-ala-d/l-glu epimerase
119d2blna2



not modelled 56.5 16 Fold:Formyltransferase
Superfamily:Formyltransferase
Family:Formyltransferase
120d1jpma1



not modelled 56.1 12 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:D-glucarate dehydratase-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0