PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2c5sA_

Fold library id	PDB Header	Molecule	Title
c2c5sA_	PDB header: rna-binding protein	Chain: A: PDB Molecule: probable thiamine biosynthesis protein thii;	PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain

Links to external resources
Added to library: Tue Mar 16 12:45:14 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence Y E Y I L V R Y G E M G K N R S K F V S T L K D N V K F K L K K F P N I K I D A T H D R M Y I Q L N G E D H E A V S E R L K D V F G I H K F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T S T T
S S
T T
T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence N L A M K V P S E L E D I K K G A L A A F L Q V K G D V K T F K I T V H R S Y K H F P M R T M E L L P E I G G H I L E N T E D I T V D V H N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S T
S
T T
S S
T T S S S
S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence P D V N V R V E I R S G Y S Y I M C D E R M G A G G L P V G V G G K V M V L L S G G I D S P V A A Y L T M K R G V S V E A V H F H S P P F T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
S B
T T T T
S S S B T
T T T S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence S E R A K Q K V I D L A Q E L T K Y C K R V T L H L V P F T E V Q K T I N K E I P S S Y S M T V M R R M M M R I T E R I A E E R N A L A I T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G S S
S
G G G T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence T G E S L G Q V A S Q T L D S M H T I N E V T N Y P V I R P L I T M D K L E I I K I A E E I G T Y D I S I R P Y K P K R E K A N R F E A K Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S T T S
G G G
S
T T T T
T T
T S
T T S

. . . . . . . . . 360 . . . . . . . . . 370 . .

Sequence D F T P L I D E A V A N K E T M V L Q T V E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	Y	E	Y	I	L	V	R	Y	G	E	M	G	K	N	R	S	K	F	V	S	T	L	K	D	N	V	K	F	K	L	K	K	F	P	N	I	K	I	D	A	T	H	D	R	M	Y	I	Q	L	N	G	E	D	H	E	A	V	S	E	R	L	K	D	V	F	G	I	H	K	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																														T	T	T	S	T	T							S	S							T	T											T	T		T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	N	L	A	M	K	V	P	S	E	L	E	D	I	K	K	G	A	L	A	A	F	L	Q	V	K	G	D	V	K	T	F	K	I	T	V	H	R	S	Y	K	H	F	P	M	R	T	M	E	L	L	P	E	I	G	G	H	I	L	E	N	T	E	D	I	T	V	D	V	H	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S	S														T			S														T	T		S	S															T	T	S	S	S					S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	P	D	V	N	V	R	V	E	I	R	S	G	Y	S	Y	I	M	C	D	E	R	M	G	A	G	G	L	P	V	G	V	G	G	K	V	M	V	L	L	S	G	G	I	D	S	P	V	A	A	Y	L	T	M	K	R	G	V	S	V	E	A	V	H	F	H	S	P	P	F	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S									S	S														S	B		T	T	T	T									S	S	S												B	T											T	T	T	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	S	E	R	A	K	Q	K	V	I	D	L	A	Q	E	L	T	K	Y	C	K	R	V	T	L	H	L	V	P	F	T	E	V	Q	K	T	I	N	K	E	I	P	S	S	Y	S	M	T	V	M	R	R	M	M	M	R	I	T	E	R	I	A	E	E	R	N	A	L	A	I	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																G	G	G	S	S																				S		G	G	G																				T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	T	G	E	S	L	G	Q	V	A	S	Q	T	L	D	S	M	H	T	I	N	E	V	T	N	Y	P	V	I	R	P	L	I	T	M	D	K	L	E	I	I	K	I	A	E	E	I	G	T	Y	D	I	S	I	R	P	Y	K	P	K	R	E	K	A	N	R	F	E	A	K	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S	S	T	T	S										G	G	G			S					T	T	T	T													T	T						T	S														T	T	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.
Sequence	D	F	T	P	L	I	D	E	A	V	A	N	K	E	T	M	V	L	Q	T	V	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)