Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	T	K	L	T	G	Y	V	W	D	G	C	A	A	S	G	M	K	L	S	S	V	A	I	M	A	R	L	A	D	F	S	N	D	E	G	V	C	W	P	S	I	E	T	I	A	R	Q	I	G	A	G	M	S	T	V	R	T	A
Secondary structure
SS confidence
Disorder		?	?												?	?	?	?		?																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	A	R	L	E	A	E	G	W	L	T	R	K	A	R	R	Q	G	D	G	S	S	P	H	C	A	V	V	D	E	Y	H	E	H	A	T	D	A	L	Y	T	T	M	L	T	G	M	G	A	R	R	Q	P	L	M	W	A	I	T	T
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?	?																									?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	G	Y	N	I	E	G	P	C	Y	D	K	R	R	E	V	I	E	M	L	N	G	S	V	P	N	D	E	L	F	G	I	I	Y	T	V	D	E	G	D	D	W	T	D	P	Q	V	L	E	K	A	N	P	N	I	G	V	S	V	Y
Secondary structure
SS confidence
Disorder						?	?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	E	F	L	L	S	Q	Q	Q	R	A	K	N	N	A	R	L	A	N	V	F	K	T	K	H	L	N	I	W	A	S	A	R	S	A	Y	F	N	L	V	S	W	Q	S	C	E	D	K	S	L	T	L	E	Q	F	E	G	Q	P	C
Secondary structure
SS confidence
Disorder														?	?																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		I	L	A	F	D	L	A	R	K	L	D	M	N	S	M	A	R	L	Y	T	R	E	I	D	G	K	T	H	Y	Y	S	V	A	P	R	F	W	V	P	Y	D	T	V	Y	S	V	E	K	N	E	D	R	R	T	A	E	R	F	Q	K
Secondary structure
SS confidence
Disorder																																																?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		W	V	E	M	G	V	L	T	V	T	D	G	A	E	V	D	Y	R	Y	I	L	E	E	A	K	A	A	N	K	I	S	P	V	S	E	S	P	I	D	P	F	G	A	T	G	L	S	H	D	L	A	D	E	D	L	N	P	V	T	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		I	Q	N	Y	T	N	M	S	D	P	M	K	E	L	E	A	A	I	E	S	G	R	F	H	H	D	G	N	P	I	M	T	W	C	I	G	N	V	V	G	K	T	I	P	G	N	D	D	V	V	K	P	V	K	E	Q	A	E	N	K
Secondary structure
SS confidence
Disorder																																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.
Sequence		I	D	G	A	V	A	L	I	M	A	V	G	R	A	M	L	Y	E	K	E	D	T	L	S	D	H	I	E	S	Y	G	I	R	S	L
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?	?		?								?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3ezk chain B Region: 1 - 441 Aligned: 371 Modelled: 386 Confidence: 99.9% Identity: 11% PDB header:hydrolase Chain: B: PDB Molecule:dna packaging protein gp17; PDBTitle: bacteriophage t4 gp17 motor assembly based on crystal2 structures and cryo-em reconstructions Phyre2 PDB 2o0h chain A Region: 2 - 171 Aligned: 165 Modelled: 170 Confidence: 99.1% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:dna packaging protein gp17; PDBTitle: t4 gp17 atpase domain mutant complexed with atp Phyre2 PDB 3c6a chain A Region: 236 - 446 Aligned: 155 Modelled: 158 Confidence: 96.0% Identity: 10% PDB header:viral protein Chain: A: PDB Molecule:terminase large subunit; PDBTitle: crystal structure of the rb49 gp17 nuclease domain Phyre2 PDB 2wbn chain A Region: 241 - 436 Aligned: 151 Modelled: 162 Confidence: 91.0% Identity: 11% PDB header:viral protein Chain: A: PDB Molecule:terminase large subunit; PDBTitle: crystal structure of the g2p (large terminase) nuclease2 domain from the bacteriophage spp1 Phyre2 PDB 3llm chain B Region: 82 - 119 Aligned: 38 Modelled: 36 Confidence: 81.5% Identity: 24% PDB header:hydrolase Chain: B: PDB Molecule:atp-dependent rna helicase a; PDBTitle: crystal structure analysis of a rna helicase Phyre2 PDB 2f55 chain C Region: 2 - 119 Aligned: 110 Modelled: 114 Confidence: 72.3% Identity: 17% PDB header:hydrolase/dna Chain: C: PDB Molecule:polyprotein; PDBTitle: two hepatitis c virus ns3 helicase domains complexed with2 the same strand of dna Phyre2 PDB 1cu1 chain B Region: 82 - 121 Aligned: 40 Modelled: 40 Confidence: 71.9% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:protein (protease/helicase ns3); PDBTitle: crystal structure of an enzyme complex from hepatitis c2 virus Phyre2 PDB 1a1v chain A Region: 82 - 119 Aligned: 38 Modelled: 38 Confidence: 69.1% Identity: 18% PDB header:hydrolase/dna Chain: A: PDB Molecule:protein (ns3 protein); PDBTitle: hepatitis c virus ns3 helicase domain complexed with single2 stranded sdna Phyre2 PDB 1a1v chain A domain 1 Region: 82 - 119 Aligned: 38 Modelled: 38 Confidence: 68.9% Identity: 18% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RNA helicase Phyre2 PDB 3l9o chain A Region: 3 - 130 Aligned: 126 Modelled: 128 Confidence: 53.4% Identity: 7% PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome Phyre2 PDB 2xgj chain A Region: 3 - 121 Aligned: 117 Modelled: 119 Confidence: 53.1% Identity: 8% PDB header:hydrolase/rna Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: structure of mtr4, a dexh helicase involved in nuclear rna2 processing and surveillance Phyre2 PDB 3kx2 chain A Region: 82 - 121 Aligned: 40 Modelled: 40 Confidence: 50.8% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:pre-mrna-splicing factor atp-dependent rna PDBTitle: crystal structure of prp43p in complex with adp Phyre2 PDB 3dkp chain A Region: 16 - 121 Aligned: 106 Modelled: 106 Confidence: 47.3% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx52; PDBTitle: human dead-box rna-helicase ddx52, conserved domain i in complex with2 adp Phyre2 PDB 1yks chain A domain 1 Region: 82 - 120 Aligned: 39 Modelled: 39 Confidence: 46.3% Identity: 13% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RNA helicase Phyre2 PDB 2qeq chain A Region: 82 - 121 Aligned: 40 Modelled: 40 Confidence: 46.1% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:flavivirin protease ns3 catalytic subunit; PDBTitle: crystal structure of kunjin virus ns3 helicase Phyre2 PDB 1tf5 chain A domain 3 Region: 3 - 93 Aligned: 91 Modelled: 91 Confidence: 45.8% Identity: 15% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 2jlr chain A Region: 82 - 121 Aligned: 40 Modelled: 40 Confidence: 44.9% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:serine protease subunit ns3; PDBTitle: dengue virus 4 ns3 helicase in complex with amppnp Phyre2 PDB 1ymf chain A Region: 82 - 126 Aligned: 45 Modelled: 45 Confidence: 44.3% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:genome polyprotein [contains: flavivirin PDBTitle: crystal structure of yellow fever virus ns3 helicase2 complexed with adp Phyre2 PDB 3ly5 chain A Region: 15 - 121 Aligned: 107 Modelled: 107 Confidence: 43.5% Identity: 9% PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase ddx18; PDBTitle: ddx18 dead-domain Phyre2 PDB 1eiw chain A Region: 307 - 358 Aligned: 52 Modelled: 52 Confidence: 43.0% Identity: 17% Fold: Flavodoxin-like Superfamily: Hypothetical protein MTH538 Family: Hypothetical protein MTH538 Phyre2 1 c3ezkB_ 2 c2o0hA_ 3 c3c6aA_ 4 c2wbnA_ 5 c3llmB_ 6 c2f55C_ 7 c1cu1B_ 8 c1a1vA_ 9 d1a1va1 10 c3l9oA_ 11 c2xgjA_ 12 c3kx2A_ 13 c3dkpA_ 14 d1yksa1 15 c2qeqA_ 16 d1tf5a3 17 c2jlrA_ 18 c1ymfA_ 19 c3ly5A_ 20 d1eiwa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ezkB_ 99.9 11 PDB header:hydrolase Chain: B: PDB Molecule:dna packaging protein gp17; PDBTitle: bacteriophage t4 gp17 motor assembly based on crystal2 structures and cryo-em reconstructions 2 c2o0hA_ 99.1 12 PDB header:hydrolase Chain: A: PDB Molecule:dna packaging protein gp17; PDBTitle: t4 gp17 atpase domain mutant complexed with atp 3 c3c6aA_ 96.0 10 PDB header:viral protein Chain: A: PDB Molecule:terminase large subunit; PDBTitle: crystal structure of the rb49 gp17 nuclease domain 4 c2wbnA_ 91.0 11 PDB header:viral protein Chain: A: PDB Molecule:terminase large subunit; PDBTitle: crystal structure of the g2p (large terminase) nuclease2 domain from the bacteriophage spp1 5 c3llmB_ 81.5 24 PDB header:hydrolase Chain: B: PDB Molecule:atp-dependent rna helicase a; PDBTitle: crystal structure analysis of a rna helicase 6 c2f55C_ 72.3 17 PDB header:hydrolase/dna Chain: C: PDB Molecule:polyprotein; PDBTitle: two hepatitis c virus ns3 helicase domains complexed with2 the same strand of dna 7 c1cu1B_ 71.9 18 PDB header:hydrolase Chain: B: PDB Molecule:protein (protease/helicase ns3); PDBTitle: crystal structure of an enzyme complex from hepatitis c2 virus 8 c1a1vA_ 69.1 18 PDB header:hydrolase/dna Chain: A: PDB Molecule:protein (ns3 protein); PDBTitle: hepatitis c virus ns3 helicase domain complexed with single2 stranded sdna 9 d1a1va1 68.9 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RNA helicase 10 c3l9oA_ 53.4 7 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: crystal structure of mtr4, a co-factor of the nuclear exosome 11 c2xgjA_ 53.1 8 PDB header:hydrolase/rna Chain: A: PDB Molecule:atp-dependent rna helicase dob1; PDBTitle: structure of mtr4, a dexh helicase involved in nuclear rna2 processing and surveillance 12 c3kx2A_ 50.8 25 PDB header:hydrolase Chain: A: PDB Molecule:pre-mrna-splicing factor atp-dependent rna PDBTitle: crystal structure of prp43p in complex with adp 13 c3dkpA_ 47.3 11 PDB header:hydrolase Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx52; PDBTitle: human dead-box rna-helicase ddx52, conserved domain i in complex with2 adp 14 d1yksa1 46.3 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RNA helicase 15 c2qeqA_ 46.1 15 PDB header:hydrolase Chain: A: PDB Molecule:flavivirin protease ns3 catalytic subunit; PDBTitle: crystal structure of kunjin virus ns3 helicase 16 d1tf5a3 45.8 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 17 c2jlrA_ 44.9 15 PDB header:hydrolase Chain: A: PDB Molecule:serine protease subunit ns3; PDBTitle: dengue virus 4 ns3 helicase in complex with amppnp 18 c1ymfA_ 44.3 16 PDB header:hydrolase Chain: A: PDB Molecule:genome polyprotein [contains: flavivirin PDBTitle: crystal structure of yellow fever virus ns3 helicase2 complexed with adp 19 c3ly5A_ 43.5 9 PDB header:hydrolase Chain: A: PDB Molecule:atp-dependent rna helicase ddx18; PDBTitle: ddx18 dead-domain 20 d1eiwa_ 43.0 17 Fold:Flavodoxin-like Superfamily:Hypothetical protein MTH538 Family:Hypothetical protein MTH538 21 d1qwga_ not modelled 42.6 13 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 22 d1rifa_ not modelled 37.7 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:DNA helicase UvsW 23 c2z83A_ not modelled 36.9 13 PDB header:viral protein Chain: A: PDB Molecule:helicase/nucleoside triphosphatase; PDBTitle: crystal structure of catalytic domain of japanese2 encephalitis virus ns3 helicase/nucleoside triphosphatase3 at a resolution 1.8 24 d2nu7b1 not modelled 36.9 22 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 25 c2wv9A_ not modelled 36.7 15 PDB header:hydrolase Chain: A: PDB Molecule:flavivirin protease ns2b regulatory subunit, flavivirin PDBTitle: crystal structure of the ns3 protease-helicase from murray2 valley encephalitis virus 26 c2va8A_ not modelled 34.3 12 PDB header:hydrolase Chain: A: PDB Molecule:ski2-type helicase; PDBTitle: dna repair helicase hel308 27 d1vhxa_ not modelled 32.6 20 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Putative Holliday junction resolvase RuvX 28 c1qfqB_ not modelled 30.7 38 PDB header:transcription/rna Chain: B: PDB Molecule:36-mer n-terminal peptide of the n protein; PDBTitle: bacteriophage lambda n-protein-nutboxb-rna complex 29 c3ngjC_ not modelled 30.6 11 PDB header:lyase Chain: C: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica 30 d1ub3a_ not modelled 30.3 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 31 c3b6eA_ not modelled 30.1 13 PDB header:hydrolase Chain: A: PDB Molecule:interferon-induced helicase c domain-containing protein 1; PDBTitle: crystal structure of human dech-box rna helicase mda5 (melanoma2 differentiation-associated protein 5), dech-domain 32 c2zj2A_ not modelled 29.4 15 PDB header:hydrolase Chain: A: PDB Molecule:putative ski2-type helicase; PDBTitle: archaeal dna helicase hjm apo state in form 1 33 d1hv8a1 not modelled 26.4 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 34 c2zpaB_ not modelled 26.2 18 PDB header:transferase Chain: B: PDB Molecule:uncharacterized protein ypfi; PDBTitle: crystal structure of trna(met) cytidine acetyltransferase 35 d1kyqa2 not modelled 25.8 22 Fold:Siroheme synthase middle domains-like Superfamily:Siroheme synthase middle domains-like Family:Siroheme synthase middle domains-like 36 d1lrza2 not modelled 25.3 18 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:FemXAB nonribosomal peptidyltransferases 37 d1s2ma1 not modelled 22.7 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 38 d1kfia3 not modelled 22.1 12 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 39 c3oa3A_ not modelled 20.7 11 PDB header:lyase Chain: A: PDB Molecule:aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis 40 c4a4zA_ not modelled 19.9 13 PDB header:hydrolase Chain: A: PDB Molecule:antiviral helicase ski2; PDBTitle: crystal structure of the s. cerevisiae dexh helicase ski2 bound to2 amppnp 41 c2ixsB_ not modelled 19.7 22 PDB header:hydrolase Chain: B: PDB Molecule:sdai restriction endonuclease; PDBTitle: structure of sdai restriction endonuclease 42 c3o3nB_ not modelled 19.5 13 PDB header:lyase Chain: B: PDB Molecule:beta-subunit 2-hydroxyacyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa 43 c1gm5A_ not modelled 18.5 13 PDB header:helicase Chain: A: PDB Molecule:recg; PDBTitle: structure of recg bound to three-way dna junction 44 d2fz4a1 not modelled 18.2 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 45 c3rc8A_ not modelled 17.2 17 PDB header:hydrolase/rna Chain: A: PDB Molecule:atp-dependent rna helicase supv3l1, mitochondrial; PDBTitle: human mitochondrial helicase suv3 in complex with short rna fragment 46 c2vbcA_ not modelled 16.0 15 PDB header:hydrolase Chain: A: PDB Molecule:dengue 4 ns3 full-length protein; PDBTitle: crystal structure of the ns3 protease-helicase from dengue2 virus 47 d1o0ya_ not modelled 15.9 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 48 d1n7ka_ not modelled 14.5 8 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 49 d2eyqa3 not modelled 14.2 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 50 c3berA_ not modelled 14.1 7 PDB header:hydrolase Chain: A: PDB Molecule:probable atp-dependent rna helicase ddx47; PDBTitle: human dead-box rna-helicase ddx47, conserved domain i in complex with2 amp 51 d3pmga3 not modelled 12.5 15 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 52 c2p6uA_ not modelled 12.4 21 PDB header:dna binding protein Chain: A: PDB Molecule:afuhel308 helicase; PDBTitle: apo structure of the hel308 superfamily 2 helicase 53 d1uaaa2 not modelled 11.2 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 54 d1gm5a3 not modelled 11.1 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 55 d1uc8a1 not modelled 10.3 11 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Lysine biosynthesis enzyme LysX, N-terminal domain 56 d1q0ua_ not modelled 10.3 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 57 c2v6jA_ not modelled 10.2 11 PDB header:hydrolase Chain: A: PDB Molecule:rna helicase; PDBTitle: kokobera virus helicase: mutant met47thr 58 d1mzra_ not modelled 9.6 9 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 59 d2dl6a1 not modelled 9.2 11 Fold:GYF/BRK domain-like Superfamily:BRK domain-like Family:BRK domain-like 60 d2htja1 not modelled 9.2 7 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FaeA-like 61 d2g9na1 not modelled 8.8 9 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 62 d1wp9a1 not modelled 8.6 21 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 63 c3pxiB_ not modelled 8.5 12 PDB header:protein binding Chain: B: PDB Molecule:negative regulator of genetic competence clpc/mecb; PDBTitle: structure of meca108:clpc 64 d1hxra_ not modelled 8.4 5 Fold:Mss4-like Superfamily:Mss4-like Family:RabGEF Mss4 65 d1oywa2 not modelled 8.3 24 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 66 c3o3nA_ not modelled 8.3 4 PDB header:lyase Chain: A: PDB Molecule:alpha-subunit 2-hydroxyisocaproyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa 67 d1mv5a_ not modelled 8.1 8 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 68 d2p6ra3 not modelled 8.1 26 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 69 d1nkta3 not modelled 7.9 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 70 d2fu5a1 not modelled 7.9 5 Fold:Mss4-like Superfamily:Mss4-like Family:RabGEF Mss4 71 d1gkub1 not modelled 7.9 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Helicase-like "domain" of reverse gyrase 72 d1hjra_ not modelled 7.9 14 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:RuvC resolvase 73 c2vl7A_ not modelled 7.8 11 PDB header:unknown function Chain: A: PDB Molecule:xpd; PDBTitle: structure of s. tokodaii xpd4 74 c3n6jA_ not modelled 7.6 15 PDB header:isomerase Chain: A: PDB Molecule:mandelate racemase/muconate lactonizing protein; PDBTitle: crystal structure of mandelate racemase/muconate lactonizing protein2 from actinobacillus succinogenes 130z 75 d2ckaa1 not modelled 7.2 9 Fold:GYF/BRK domain-like Superfamily:BRK domain-like Family:BRK domain-like 76 c2ckaA_ not modelled 7.2 9 PDB header:hydrolase Chain: A: PDB Molecule:chromodomain-helicase-dna-binding protein 8; PDBTitle: solution structures of the brk domains of the human chromo2 helicase domain 7 and 8, reveals structural similarity3 with gyf domain suggesting a role in protein interaction 77 d2e8aa1 not modelled 6.8 11 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 78 c2chvE_ not modelled 6.7 13 PDB header:dna-binding protein Chain: E: PDB Molecule:replication factor c small subunit; PDBTitle: replication factor c adpnp complex 79 c3d8bB_ not modelled 6.7 15 PDB header:hydrolase Chain: B: PDB Molecule:fidgetin-like protein 1; PDBTitle: crystal structure of human fidgetin-like protein 1 in complex with adp 80 c2r2aB_ not modelled 6.7 20 PDB header:toxin Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of n-terminal domain of zonular occludens toxin from2 neisseria meningitidis 81 c3fe2B_ not modelled 6.6 13 PDB header:hydrolase Chain: B: PDB Molecule:probable atp-dependent rna helicase ddx5; PDBTitle: human dead-box rna helicase ddx5 (p68), conserved domain i in complex2 with adp 82 d2fwra2 not modelled 6.5 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 83 d1pjqa3 not modelled 6.5 28 Fold:Siroheme synthase middle domains-like Superfamily:Siroheme synthase middle domains-like Family:Siroheme synthase middle domains-like 84 d1mzha_ not modelled 6.3 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 85 d2j0sa1 not modelled 6.3 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 86 c2fsgA_ not modelled 6.3 16 PDB header:protein transport Chain: A: PDB Molecule:preprotein translocase seca subunit; PDBTitle: complex seca:atp from escherichia coli 87 d1fx0b1 not modelled 6.2 18 Fold:Left-handed superhelix Superfamily:C-terminal domain of alpha and beta subunits of F1 ATP synthase Family:C-terminal domain of alpha and beta subunits of F1 ATP synthase 88 c3pfiB_ not modelled 5.9 19 PDB header:hydrolase Chain: B: PDB Molecule:holliday junction atp-dependent dna helicase ruvb; PDBTitle: 2.7 angstrom resolution crystal structure of a probable holliday2 junction dna helicase (ruvb) from campylobacter jejuni subsp. jejuni3 nctc 11168 in complex with adenosine-5'-diphosphate 89 c3iuyB_ not modelled 5.7 14 PDB header:hydrolase Chain: B: PDB Molecule:probable atp-dependent rna helicase ddx53; PDBTitle: crystal structure of ddx53 dead-box domain 90 d1ir1s_ not modelled 5.6 20 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 91 c3o0kB_ not modelled 5.4 7 PDB header:oxidoreductase Chain: B: PDB Molecule:aldo/keto reductase; PDBTitle: crystal structure of aldo/keto reductase from brucella melitensis 92 c1nsfA_ not modelled 5.4 20 PDB header:protein transport Chain: A: PDB Molecule:n-ethylmaleimide sensitive factor; PDBTitle: d2 hexamerization domain of n-ethylmaleimide sensitive factor (nsf) 93 d1fvpa_ not modelled 5.3 33 Fold:TIM beta/alpha-barrel Superfamily:Bacterial luciferase-like Family:Non-fluorescent flavoprotein (luxF, FP390) 94 d1u83a_ not modelled 5.3 12 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 95 c1u83A_ not modelled 5.3 12 PDB header:lyase Chain: A: PDB Molecule:phosphosulfolactate synthase; PDBTitle: psl synthase from bacillus subtilis 96 d1nnva_ not modelled 5.3 14 Fold:Cystatin-like Superfamily:Putative dsDNA mimic Family:Putative dsDNA mimic 97 c1qhhB_ not modelled 5.2 6 PDB header:hydrolase Chain: B: PDB Molecule:protein (pcra (subunit)); PDBTitle: structure of dna helicase with adpnp 98 d2v0ea1 not modelled 5.1 25 Fold:GYF/BRK domain-like Superfamily:BRK domain-like Family:BRK domain-like 99 d2fkia1 not modelled 5.1 17 Fold:Secretion chaperone-like Superfamily:YjbR-like Family:YjbR-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0