Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	R	F	I	Q	G	D	C	V	R	V	M	A	T	F	P	G	N	A	V	D	F	I	L	T	D	P	P	Y	L	V	G	F	R	D	R	Q	G	R	T	I	A	G	D	K	T	D	E	W	L	Q	P	A	C	N	E	M	Y	R
Secondary structure
SS confidence
Disorder		?	?	?																																	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	L	K	K	D	A	L	M	V	S	F	Y	G	W	N	R	V	D	R	F	M	A	A	W	K	N	A	G	F	S	V	V	G	H	L	V	F	T	K	T	Y	T	S	K	A	A	Y	V	G	Y	R	H	E	C	A	Y	I	L	A	K
Secondary structure
SS confidence
Disorder																																											?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	R	P	A	L	P	Q	K	P	L	P	D	V	L	G	W	K	Y	S	G	N	R	H	H	P	T	E	K	P	V	T	S	L	Q	P	L	I	E	S	F	T	H	P	N	A	I	V	L	D	P	F	A	G	S	G	S	T	C	V	A
Secondary structure
SS confidence
Disorder																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
Sequence		A	L	Q	S	G	R	R	Y	I	G	I	E	L	L	E	Q	Y	H	R	A	G	Q	Q	R	L	A	A	V	Q	R	A	M	Q	Q	G	A	A	N	D	D	W	F	M	P	E	A	A
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?	?	?				?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1g60 chain A Region: 1 - 207 Aligned: 206 Modelled: 207 Confidence: 100.0% Identity: 21% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Type II DNA methylase Phyre2 PDB 2zif chain B Region: 1 - 208 Aligned: 203 Modelled: 208 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: B: PDB Molecule:putative modification methylase; PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine Phyre2 PDB 1nw6 chain A Region: 2 - 224 Aligned: 219 Modelled: 223 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:modification methylase rsri; PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin Phyre2 PDB 1eg2 chain A Region: 2 - 207 Aligned: 202 Modelled: 206 Confidence: 100.0% Identity: 26% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Type II DNA methylase Phyre2 PDB 1boo chain A Region: 2 - 205 Aligned: 203 Modelled: 204 Confidence: 100.0% Identity: 20% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Type II DNA methylase Phyre2 PDB 3ldu chain A Region: 138 - 208 Aligned: 71 Modelled: 71 Confidence: 98.7% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:putative methylase; PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630. Phyre2 PDB 3k0b chain A Region: 140 - 208 Aligned: 69 Modelled: 69 Confidence: 98.7% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted n6-adenine-specific dna methylase; PDBTitle: crystal structure of a predicted n6-adenine-specific dna methylase2 from listeria monocytogenes str. 4b f2365 Phyre2 PDB 3ldg chain A Region: 138 - 208 Aligned: 71 Modelled: 71 Confidence: 98.6% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein smu.472; PDBTitle: crystal structure of smu.472, a putative methyltransferase complexed2 with sah Phyre2 PDB 3gdh chain C Region: 147 - 207 Aligned: 61 Modelled: 61 Confidence: 98.4% Identity: 16% PDB header:transferase Chain: C: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form) Phyre2 PDB 2ar0 chain A domain 1 Region: 149 - 205 Aligned: 57 Modelled: 56 Confidence: 98.4% Identity: 32% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: N-6 DNA Methylase-like Phyre2 PDB 2fhp chain A domain 1 Region: 144 - 222 Aligned: 77 Modelled: 79 Confidence: 98.3% Identity: 18% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: YhhF-like Phyre2 PDB 3egi chain A Region: 149 - 208 Aligned: 60 Modelled: 60 Confidence: 98.3% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase tgs1 bound to m7gpppa (inactive form) Phyre2 PDB 3a27 chain A Region: 157 - 207 Aligned: 51 Modelled: 51 Confidence: 98.3% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein mj1557; PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet Phyre2 PDB 1wy7 chain A domain 1 Region: 144 - 206 Aligned: 63 Modelled: 63 Confidence: 98.2% Identity: 24% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Ta1320-like Phyre2 PDB 3p9n chain A Region: 150 - 208 Aligned: 59 Modelled: 59 Confidence: 98.2% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:possible methyltransferase (methylase); PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase Phyre2 PDB 3a26 chain A Region: 154 - 207 Aligned: 54 Modelled: 54 Confidence: 98.2% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein ph0793; PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado Phyre2 PDB 3lpm chain A Region: 3 - 108 Aligned: 88 Modelled: 88 Confidence: 98.2% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase small domain protein2 from listeria monocytogenes Phyre2 PDB 3mti chain A Region: 147 - 208 Aligned: 62 Modelled: 62 Confidence: 98.2% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:rrna methylase; PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a Phyre2 PDB 2frn chain A domain 1 Region: 154 - 206 Aligned: 53 Modelled: 53 Confidence: 98.1% Identity: 21% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Met-10+ protein-like Phyre2 PDB 2okc chain A domain 1 Region: 149 - 205 Aligned: 57 Modelled: 54 Confidence: 98.1% Identity: 19% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: N-6 DNA Methylase-like Phyre2 1 d1g60a_ 2 c2zifB_ 3 c1nw6A_ 4 d1eg2a_ 5 d1booa_ 6 c3lduA_ 7 c3k0bA_ 8 c3ldgA_ 9 c3gdhC_ 10 d2ar0a1 11 d2fhpa1 12 c3egiA_ 13 c3a27A_ 14 d1wy7a1 15 c3p9nA_ 16 c3a26A_ 17 c3lpmA_ 18 c3mtiA_ 19 d2frna1 20 d2okca1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1g60a_ 100.0 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 2 c2zifB_ 100.0 26 PDB header:transferase Chain: B: PDB Molecule:putative modification methylase; PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine 3 c1nw6A_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:modification methylase rsri; PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin 4 d1eg2a_ 100.0 26 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 5 d1booa_ 100.0 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 6 c3lduA_ 98.7 21 PDB header:transferase Chain: A: PDB Molecule:putative methylase; PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630. 7 c3k0bA_ 98.7 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted n6-adenine-specific dna methylase; PDBTitle: crystal structure of a predicted n6-adenine-specific dna methylase2 from listeria monocytogenes str. 4b f2365 8 c3ldgA_ 98.6 21 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein smu.472; PDBTitle: crystal structure of smu.472, a putative methyltransferase complexed2 with sah 9 c3gdhC_ 98.4 16 PDB header:transferase Chain: C: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form) 10 d2ar0a1 98.4 32 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N-6 DNA Methylase-like 11 d2fhpa1 98.3 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 12 c3egiA_ 98.3 17 PDB header:transferase Chain: A: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase tgs1 bound to m7gpppa (inactive form) 13 c3a27A_ 98.3 18 PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein mj1557; PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet 14 d1wy7a1 98.2 24 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Ta1320-like 15 c3p9nA_ 98.2 20 PDB header:transferase Chain: A: PDB Molecule:possible methyltransferase (methylase); PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase 16 c3a26A_ 98.2 20 PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein ph0793; PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado 17 c3lpmA_ 98.2 14 PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase small domain protein2 from listeria monocytogenes 18 c3mtiA_ 98.2 18 PDB header:transferase Chain: A: PDB Molecule:rrna methylase; PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a 19 d2frna1 98.1 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Met-10+ protein-like 20 d2okca1 98.1 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N-6 DNA Methylase-like 21 c3khkA_ not modelled 98.1 21 PDB header:dna binding protein Chain: A: PDB Molecule:type i restriction-modification system PDBTitle: crystal structure of type-i restriction-modification system2 methylation subunit (mm_0429) from methanosarchina mazei. 22 d2ifta1 not modelled 98.1 27 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 23 d1ws6a1 not modelled 98.0 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 24 c2yx1A_ not modelled 98.0 19 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein mj0883; PDBTitle: crystal structure of m.jannaschii trna m1g37 methyltransferase 25 d2as0a2 not modelled 98.0 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase 26 c3lkdB_ not modelled 98.0 23 PDB header:transferase Chain: B: PDB Molecule:type i restriction-modification system PDBTitle: crystal structure of the type i restriction-modification2 system methyltransferase subunit from streptococcus3 thermophilus, northeast structural genomics consortium4 target sur80 27 d2nxca1 not modelled 98.0 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Ribosomal protein L11 methyltransferase PrmA 28 c3grzA_ not modelled 97.9 21 PDB header:transferase Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase; PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus 29 c2esrB_ not modelled 97.9 23 PDB header:transferase Chain: B: PDB Molecule:methyltransferase; PDBTitle: conserved hypothetical protein- streptococcus pyogenes 30 c1aqjB_ not modelled 97.9 19 PDB header:methyltransferase Chain: B: PDB Molecule:adenine-n6-dna-methyltransferase taqi; PDBTitle: structure of adenine-n6-dna-methyltransferase taqi 31 c3bt7A_ not modelled 97.9 19 PDB header:transferase/rna Chain: A: PDB Molecule:trna (uracil-5-)-methyltransferase; PDBTitle: structure of e. coli 5-methyluridine methyltransferase trma2 in complex with 19 nucleotide t-arm analogue 32 d2fpoa1 not modelled 97.9 29 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 33 d1uwva2 not modelled 97.9 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:(Uracil-5-)-methyltransferase 34 c1g38A_ not modelled 97.8 17 PDB header:transferase/dna Chain: A: PDB Molecule:modification methylase taqi; PDBTitle: adenine-specific methyltransferase m. taq i/dna complex 35 d2b3ta1 not modelled 97.8 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N5-glutamine methyltransferase, HemK 36 c2as0A_ not modelled 97.8 23 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ph1915; PDBTitle: crystal structure of ph1915 (apc 5817): a hypothetical rna2 methyltransferase 37 c3njrB_ not modelled 97.8 22 PDB header:transferase Chain: B: PDB Molecule:precorrin-6y methylase; PDBTitle: crystal structure of c-terminal domain of precorrin-6y c5,15-2 methyltransferase from rhodobacter capsulatus 38 d2f8la1 not modelled 97.8 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N-6 DNA Methylase-like 39 d1wxxa2 not modelled 97.8 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase 40 c3s1sA_ not modelled 97.7 18 PDB header:hydrolase, transferase Chain: A: PDB Molecule:restriction endonuclease bpusi; PDBTitle: characterization and crystal structure of the type iig restriction2 endonuclease bpusi 41 d1ne2a_ not modelled 97.7 9 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Ta1320-like 42 c2yvlB_ not modelled 97.7 19 PDB header:transferase Chain: B: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of trna (m1a58) methyltransferase trmi from aquifex2 aeolicus 43 d1nv8a_ not modelled 97.7 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N5-glutamine methyltransferase, HemK 44 c1wg8B_ not modelled 97.7 17 PDB header:transferase Chain: B: PDB Molecule:predicted s-adenosylmethionine-dependent PDBTitle: crystal structure of a predicted s-adenosylmethionine-2 dependent methyltransferase tt1512 from thermus3 thermophilus hb8. 45 d1wg8a2 not modelled 97.7 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:MraW-like putative methyltransferases 46 c2ozvA_ not modelled 97.7 13 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein atu0636; PDBTitle: crystal structure of a predicted o-methyltransferase, protein atu6362 from agrobacterium tumefaciens. 47 c1uwvA_ not modelled 97.7 22 PDB header:transferase Chain: A: PDB Molecule:23s rrna (uracil-5-)-methyltransferase ruma; PDBTitle: crystal structure of ruma, the iron-sulfur cluster2 containing e. coli 23s ribosomal rna 5-methyluridine3 methyltransferase 48 c3c6kC_ not modelled 97.7 18 PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine 49 d1qama_ not modelled 97.7 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA adenine dimethylase-like 50 d2b78a2 not modelled 97.7 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase 51 c3eeyJ_ not modelled 97.7 16 PDB header:transferase Chain: J: PDB Molecule:putative rrna methylase; PDBTitle: crystal structure of putative rrna-methylase from clostridium2 thermocellum 52 d2esra1 not modelled 97.7 27 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 53 d1dusa_ not modelled 97.7 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Hypothetical protein MJ0882 54 d2ih2a1 not modelled 97.6 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:DNA methylase TaqI, N-terminal domain 55 c2vs1A_ not modelled 97.6 16 PDB header:transferase Chain: A: PDB Molecule:uncharacterized rna methyltransferase pyrab10780; PDBTitle: the crystal structure of pyrococcus abyssi trna (uracil-54,2 c5)-methyltransferase in complex with s-adenosyl-l-3 homocysteine 56 c2yxdA_ not modelled 97.6 19 PDB header:transferase Chain: A: PDB Molecule:probable cobalt-precorrin-6y c(15)-methyltransferase PDBTitle: crystal structure of cobalamin biosynthesis precorrin 8w decarboxylase2 (cbit) 57 c1wxwA_ not modelled 97.6 14 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ttha1280; PDBTitle: crystal structure of tt1595, a putative sam-dependent2 methyltransferase from thermus thermophillus hb8 58 c2b78A_ not modelled 97.6 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein smu.776; PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans 59 c3c0kB_ not modelled 97.6 13 PDB header:transferase Chain: B: PDB Molecule:upf0064 protein yccw; PDBTitle: crystal structure of a ribosomal rna methyltranferase 60 d2b25a1 not modelled 97.5 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:tRNA(1-methyladenosine) methyltransferase-like 61 c3gnlB_ not modelled 97.5 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein, duf633, lmof2365_1472; PDBTitle: structure of uncharacterized protein (lmof2365_1472) from2 listeria monocytogenes serotype 4b 62 d1l3ia_ not modelled 97.5 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Precorrin-6Y methyltransferase (CbiT) 63 d1zq9a1 not modelled 97.5 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA adenine dimethylase-like 64 c3evzA_ not modelled 97.5 10 PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: crystal strucure of methyltransferase from pyrococcus furiosus 65 d1yzha1 not modelled 97.5 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TrmB-like 66 c3fydA_ not modelled 97.5 14 PDB header:transferase Chain: A: PDB Molecule:probable dimethyladenosine transferase; PDBTitle: crystal structure of dim1 from the thermophilic archeon,2 methanocaldococcus jannaschi 67 c3dmgA_ not modelled 97.5 24 PDB header:transferase Chain: A: PDB Molecule:probable ribosomal rna small subunit methyltransferase; PDBTitle: t. thermophilus 16s rrna n2 g1207 methyltransferase (rsmc) in complex2 with adohcy 68 c3q87B_ not modelled 97.5 15 PDB header:transferase activator/transferase Chain: B: PDB Molecule:n6 adenine specific dna methylase; PDBTitle: structure of eukaryotic translation termination complex2 methyltransferase mtq2-trm112 69 c3lecA_ not modelled 97.5 19 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:nadb-rossmann superfamily protein; PDBTitle: the crystal structure of a protein in the nadb-rossmann2 superfamily from streptococcus agalactiae to 1.8a 70 d1o9ga_ not modelled 97.5 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA methyltransferase AviRa 71 d2igta1 not modelled 97.5 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase 72 d1pjza_ not modelled 97.4 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Thiopurine S-methyltransferase 73 d1xj5a_ not modelled 97.4 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Spermidine synthase 74 c3grrA_ not modelled 97.4 14 PDB header:transferase Chain: A: PDB Molecule:dimethyladenosine transferase; PDBTitle: crystal structure of the complex between s-adenosyl homocysteine and2 methanocaldococcus jannaschi dim1. 75 c2pjdA_ not modelled 97.4 14 PDB header:transferase Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase c; PDBTitle: crystal structure of 16s rrna methyltransferase rsmc 76 c3e05B_ not modelled 97.4 20 PDB header:transferase Chain: B: PDB Molecule:precorrin-6y c5,15-methyltransferase (decarboxylating); PDBTitle: crystal structure of precorrin-6y c5,15-methyltransferase from2 geobacter metallireducens gs-15 77 c3g5tA_ not modelled 97.4 17 PDB header:transferase Chain: A: PDB Molecule:trans-aconitate 3-methyltransferase; PDBTitle: crystal structure of trans-aconitate 3-methyltransferase2 from yeast 78 c1m6yA_ not modelled 97.4 27 PDB header:transferase Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw; PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah 79 d1o54a_ not modelled 97.3 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:tRNA(1-methyladenosine) methyltransferase-like 80 c3bwbA_ not modelled 97.3 16 PDB header:transferase Chain: A: PDB Molecule:spermidine synthase; PDBTitle: crystal structure of the apo form of spermidine synthase from2 trypanosoma cruzi at 2.5 a resolution 81 c2pwyB_ not modelled 97.3 20 PDB header:transferase Chain: B: PDB Molecule:trna (adenine-n(1)-)-methyltransferase; PDBTitle: crystal structure of a m1a58 trna methyltransferase 82 c1u2zC_ not modelled 97.3 18 PDB header:transferase Chain: C: PDB Molecule:histone-lysine n-methyltransferase, h3 lysine-79 PDBTitle: crystal structure of histone k79 methyltransferase dot1p2 from yeast 83 c3fuxB_ not modelled 97.3 19 PDB header:transferase Chain: B: PDB Molecule:dimethyladenosine transferase; PDBTitle: t. thermophilus 16s rrna a1518 and a1519 methyltransferase (ksga) in2 complex with 5'-methylthioadenosine in space group p212121 84 c3ku1E_ not modelled 97.3 23 PDB header:transferase Chain: E: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine 85 c2q41D_ not modelled 97.3 15 PDB header:transferase Chain: D: PDB Molecule:spermidine synthase 1; PDBTitle: ensemble refinement of the protein crystal structure of spermidine2 synthase from arabidopsis thaliana gene at1g23820 86 c3tqsB_ not modelled 97.3 13 PDB header:transferase Chain: B: PDB Molecule:ribosomal rna small subunit methyltransferase a; PDBTitle: structure of the dimethyladenosine transferase (ksga) from coxiella2 burnetii 87 c2h1rA_ not modelled 97.3 21 PDB header:transferase Chain: A: PDB Molecule:dimethyladenosine transferase, putative; PDBTitle: crystal structure of a dimethyladenosine transferase from2 plasmodium falciparum 88 c1nw3A_ not modelled 97.2 13 PDB header:transferase Chain: A: PDB Molecule:histone methyltransferase dot1l; PDBTitle: structure of the catalytic domain of human dot1l, a non-set2 domain nucleosomal histone methyltransferase 89 d1nw3a_ not modelled 97.2 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Catalytic, N-terminal domain of histone methyltransferase Dot1l 90 d2fcaa1 not modelled 97.2 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TrmB-like 91 d1i1na_ not modelled 97.2 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Protein-L-isoaspartyl O-methyltransferase 92 c3ll7A_ not modelled 97.2 17 PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase pg_1098 from2 porphyromonas gingivalis w83 93 c3a4tA_ not modelled 97.2 15 PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase mj0026; PDBTitle: crystal structure of atrm4 from m.jannaschii with sinefungin 94 d1qyra_ not modelled 97.2 9 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA adenine dimethylase-like 95 c2fk8A_ not modelled 97.1 25 PDB header:transferase Chain: A: PDB Molecule:methoxy mycolic acid synthase 4; PDBTitle: crystal structure of hma (mmaa4) from mycobacterium tuberculosis2 complexed with s-adenosylmethionine 96 d2h00a1 not modelled 97.1 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Methyltransferase 10 domain 97 d1uira_ not modelled 97.1 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Spermidine synthase 98 c3bxoA_ not modelled 97.1 22 PDB header:transferase Chain: A: PDB Molecule:n,n-dimethyltransferase; PDBTitle: crystal structure of streptomyces venezuelae desvi 99 c3cggB_ not modelled 97.1 22 PDB header:transferase Chain: B: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of tehb-like sam-dependent methyltransferase2 (np_600671.1) from corynebacterium glutamicum atcc 13032 kitasato at3 2.00 a resolution 100 c3m33B_ not modelled 97.1 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of a functionally unknown protein from2 deinococcus radiodurans r1 101 d1kpia_ not modelled 97.0 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase 102 d2b9ea1 not modelled 97.0 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:NOL1/NOP2/sun 103 c2e58D_ not modelled 97.0 12 PDB header:transferase Chain: D: PDB Molecule:mnmc2; PDBTitle: crystal structure of mnmc2 from aquifex aeolicus 104 c1z3cA_ not modelled 97.0 25 PDB header:transferase Chain: A: PDB Molecule:mrna capping enzyme; PDBTitle: encephalitozooan cuniculi mrna cap (guanine-n7)2 methyltransferasein complexed with azoadomet 105 d1l1ea_ not modelled 97.0 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase 106 d1ri5a_ not modelled 97.0 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:mRNA cap (Guanine N-7) methyltransferase 107 d1wzna1 not modelled 97.0 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:CAC2371-like 108 c3bgvC_ not modelled 97.0 15 PDB header:transferase Chain: C: PDB Molecule:mrna cap guanine-n7 methyltransferase; PDBTitle: crystal structure of mrna cap guanine-n7 methyltransferase2 in complex with sah 109 d1nt2a_ not modelled 97.0 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Fibrillarin homologue 110 d2bzga1 not modelled 97.0 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Thiopurine S-methyltransferase 111 d1i9ga_ not modelled 96.9 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:tRNA(1-methyladenosine) methyltransferase-like 112 c3mb5A_ not modelled 96.9 12 PDB header:transferase Chain: A: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of p. abyssi trna m1a58 methyltransferase in complex2 with s-adenosyl-l-methionine 113 d1sqga2 not modelled 96.9 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:NOL1/NOP2/sun 114 c3hm2G_ not modelled 96.9 22 PDB header:transferase Chain: G: PDB Molecule:precorrin-6y c5,15-methyltransferase; PDBTitle: crystal structure of putative precorrin-6y c5,15-2 methyltransferase targeted domain from corynebacterium3 diphtheriae 115 c3gjyA_ not modelled 96.9 18 PDB header:transferase Chain: A: PDB Molecule:spermidine synthase; PDBTitle: crystal structure of a probable spermidine synthase from2 corynebacterium glutamicum atcc 13032 116 d1kpga_ not modelled 96.9 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase 117 c1yb2A_ not modelled 96.8 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ta0852; PDBTitle: structure of a putative methyltransferase from thermoplasma2 acidophilum. 118 d1yb2a1 not modelled 96.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:tRNA(1-methyladenosine) methyltransferase-like 119 c3bgdB_ not modelled 96.8 15 PDB header:transferase Chain: B: PDB Molecule:thiopurine s-methyltransferase; PDBTitle: thiopurine s-methyltransferase 120 c3lbfC_ not modelled 96.8 17 PDB header:transferase Chain: C: PDB Molecule:protein-l-isoaspartate o-methyltransferase; PDBTitle: crystal structure of protein l-isoaspartyl methyltransferase from2 escherichia coli

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0