Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	L	K	I	S	P	E	L	L	Q	I	S	P	E	V	Q	D	A	L	K	N	K	K	P	V	V	A	L	E	S	T	I	I	S	H	G	M	P	F	P	Q	N	A	Q	T	A	I	E	V	E	E	T	I	R	K	Q	G	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																									?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	P	A	T	I	A	I	I	G	G	V	M	K	V	G	L	S	K	E	E	I	E	L	L	G	R	E	G	H	N	V	T	K	V	S	R	R	D	L	P	F	V	V	A	A	G	K	N	G	A	T	T	V	A	S	T	M	I	I	A
Secondary structure
SS confidence
Disorder																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	A	G	I	K	V	F	A	T	G	G	I	G	G	V	H	R	G	A	E	H	T	F	D	I	S	A	D	L	Q	E	L	A	N	T	N	V	T	V	V	C	A	G	A	K	S	I	L	D	L	G	L	T	T	E	Y	L	E	T
Secondary structure
SS confidence
Disorder																			?						?										?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	G	V	P	L	I	G	Y	Q	T	K	A	L	P	A	F	F	C	R	T	S	P	F	D	V	S	I	R	L	D	S	A	S	E	I	A	R	A	M	V	V	K	W	Q	S	G	L	N	G	G	L	V	V	A	N	P	I	P	E	Q
Secondary structure
SS confidence
Disorder																																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		F	A	M	P	E	H	T	I	N	A	A	I	D	Q	A	V	A	E	A	E	A	Q	G	V	I	G	K	E	S	T	P	F	L	L	A	R	V	A	E	L	T	G	G	D	S	L	K	S	N	I	Q	L	V	F	N	N	A	I	L	A
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.
Sequence		S	E	I	A	K	E	Y	Q	R	L	A	G
Secondary structure
SS confidence
Disorder											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1vkm chain A Region: 14 - 309 Aligned: 285 Modelled: 295 Confidence: 100.0% Identity: 38% Fold: Indigoidine synthase A-like Superfamily: Indigoidine synthase A-like Family: Indigoidine synthase A-like Phyre2 PDB 1otp chain A Region: 75 - 258 Aligned: 169 Modelled: 184 Confidence: 93.4% Identity: 21% PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase Phyre2 PDB 2j0f chain C Region: 75 - 262 Aligned: 173 Modelled: 182 Confidence: 93.1% Identity: 21% PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design Phyre2 PDB 1brw chain B Region: 75 - 300 Aligned: 211 Modelled: 226 Confidence: 93.1% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation Phyre2 PDB 2dsj chain A Region: 75 - 237 Aligned: 148 Modelled: 163 Confidence: 92.3% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 Phyre2 PDB 3h5q chain A Region: 75 - 236 Aligned: 147 Modelled: 154 Confidence: 91.6% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus Phyre2 PDB 1zfj chain A Region: 15 - 133 Aligned: 105 Modelled: 112 Confidence: 91.5% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes Phyre2 PDB 1s2w chain A Region: 114 - 260 Aligned: 135 Modelled: 147 Confidence: 90.8% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 1zfj chain A domain 1 Region: 15 - 133 Aligned: 105 Modelled: 109 Confidence: 86.1% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Inosine monophosphate dehydrogenase (IMPDH) Family: Inosine monophosphate dehydrogenase (IMPDH) Phyre2 PDB 1mum chain A Region: 114 - 260 Aligned: 140 Modelled: 147 Confidence: 83.9% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 1khd chain D Region: 75 - 197 Aligned: 106 Modelled: 123 Confidence: 83.0% Identity: 21% PDB header:transferase Chain: D: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: crystal structure analysis of the anthranilate2 phosphoribosyltransferase from erwinia carotovora at 1.93 resolution (current name, pectobacterium carotovorum) Phyre2 PDB 2fr1 chain A Region: 127 - 251 Aligned: 102 Modelled: 108 Confidence: 81.4% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:erythromycin synthase, eryai; PDBTitle: the first ketoreductase of the erythromycin synthase2 (crystal form 2) Phyre2 PDB 2elc chain A domain 2 Region: 92 - 197 Aligned: 90 Modelled: 100 Confidence: 80.4% Identity: 27% Fold: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Phyre2 PDB 1v8g chain B Region: 75 - 196 Aligned: 106 Modelled: 122 Confidence: 79.7% Identity: 28% PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: crystal structure of anthranilate phosphoribosyltransferase2 (trpd) from thermus thermophilus hb8 Phyre2 PDB 1o17 chain A Region: 75 - 198 Aligned: 106 Modelled: 124 Confidence: 78.1% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: anthranilate phosphoribosyl-transferase (trpd) Phyre2 PDB 2vz8 chain B Region: 127 - 232 Aligned: 83 Modelled: 89 Confidence: 77.7% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase; PDBTitle: crystal structure of mammalian fatty acid synthase Phyre2 PDB 3mjs chain A Region: 127 - 256 Aligned: 107 Modelled: 113 Confidence: 76.3% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:amphb; PDBTitle: structure of a-type ketoreductases from modular polyketide synthase Phyre2 PDB 1jvn chain A domain 1 Region: 106 - 185 Aligned: 69 Modelled: 80 Confidence: 74.0% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Histidine biosynthesis enzymes Phyre2 PDB 2z5l chain A Region: 127 - 191 Aligned: 59 Modelled: 65 Confidence: 73.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:tylactone synthase starter module and modules 1 PDBTitle: the first ketoreductase of the tylosin pks Phyre2 PDB 1r7h chain A Region: 1 - 84 Aligned: 71 Modelled: 71 Confidence: 68.3% Identity: 20% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 1 d1vkma_ 2 c1otpA_ 3 c2j0fC_ 4 c1brwB_ 5 c2dsjA_ 6 c3h5qA_ 7 c1zfjA_ 8 d1s2wa_ 9 d1zfja1 10 d1muma_ 11 c1khdD_ 12 c2fr1A_ 13 d2elca2 14 c1v8gB_ 15 c1o17A_ 16 c2vz8B_ 17 c3mjsA_ 18 d1jvna1 19 c2z5lA_ 20 d1r7ha_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1vkma_ 100.0 38 Fold:Indigoidine synthase A-like Superfamily:Indigoidine synthase A-like Family:Indigoidine synthase A-like 2 c1otpA_ 93.4 21 PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase 3 c2j0fC_ 93.1 21 PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design 4 c1brwB_ 93.1 18 PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation 5 c2dsjA_ 92.3 20 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 6 c3h5qA_ 91.6 20 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus 7 c1zfjA_ 91.5 19 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 8 d1s2wa_ 90.8 13 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 9 d1zfja1 86.1 18 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 10 d1muma_ 83.9 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 11 c1khdD_ 83.0 21 PDB header:transferase Chain: D: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: crystal structure analysis of the anthranilate2 phosphoribosyltransferase from erwinia carotovora at 1.93 resolution (current name, pectobacterium carotovorum) 12 c2fr1A_ 81.4 17 PDB header:oxidoreductase Chain: A: PDB Molecule:erythromycin synthase, eryai; PDBTitle: the first ketoreductase of the erythromycin synthase2 (crystal form 2) 13 d2elca2 80.4 27 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 14 c1v8gB_ 79.7 28 PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: crystal structure of anthranilate phosphoribosyltransferase2 (trpd) from thermus thermophilus hb8 15 c1o17A_ 78.1 22 PDB header:transferase Chain: A: PDB Molecule:anthranilate phosphoribosyltransferase; PDBTitle: anthranilate phosphoribosyl-transferase (trpd) 16 c2vz8B_ 77.7 16 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase; PDBTitle: crystal structure of mammalian fatty acid synthase 17 c3mjsA_ 76.3 15 PDB header:oxidoreductase Chain: A: PDB Molecule:amphb; PDBTitle: structure of a-type ketoreductases from modular polyketide synthase 18 d1jvna1 74.0 23 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 19 c2z5lA_ 73.0 15 PDB header:transferase Chain: A: PDB Molecule:tylactone synthase starter module and modules 1 PDBTitle: the first ketoreductase of the tylosin pks 20 d1r7ha_ 68.3 20 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 21 c2hjpA_ not modelled 67.4 12 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 22 c1vquB_ not modelled 65.8 18 PDB header:transferase Chain: B: PDB Molecule:anthranilate phosphoribosyltransferase 2; PDBTitle: crystal structure of anthranilate phosphoribosyltransferase 22 (17130499) from nostoc sp. at 1.85 a resolution 23 c3fmfA_ not modelled 65.8 21 PDB header:ligase Chain: A: PDB Molecule:dethiobiotin synthetase; PDBTitle: crystal structure of mycobacterium tuberculosis dethiobiotin2 synthetase complexed with 7,8 diaminopelargonic acid carbamate 24 c3n2oA_ not modelled 64.6 21 PDB header:lyase Chain: A: PDB Molecule:biosynthetic arginine decarboxylase; PDBTitle: x-ray crystal structure of arginine decarboxylase complexed with2 arginine from vibrio vulnificus 25 c3khsB_ not modelled 64.2 27 PDB header:hydrolase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of grouper iridovirus purine nucleoside2 phosphorylase 26 c3lyhB_ not modelled 63.3 20 PDB header:lyase Chain: B: PDB Molecule:cobalamin (vitamin b12) biosynthesis cbix protein; PDBTitle: crystal structure of putative cobalamin (vitamin b12) biosynthesis2 cbix protein (yp_958415.1) from marinobacter aquaeolei vt8 at 1.60 a3 resolution 27 d1mzha_ not modelled 63.0 26 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 28 c3qp9C_ not modelled 59.7 16 PDB header:oxidoreductase Chain: C: PDB Molecule:type i polyketide synthase pikaii; PDBTitle: the structure of a c2-type ketoreductase from a modular polyketide2 synthase 29 d1uoua2 not modelled 59.4 23 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 30 c3nzpA_ not modelled 59.3 13 PDB header:lyase Chain: A: PDB Molecule:arginine decarboxylase; PDBTitle: crystal structure of the biosynthetic arginine decarboxylase spea from2 campylobacter jejuni, northeast structural genomics consortium target3 br53 31 c1zlpA_ not modelled 59.2 16 PDB header:lyase Chain: A: PDB Molecule:petal death protein; PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct 32 d1m3ua_ not modelled 58.1 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 33 c3ih1A_ not modelled 57.6 17 PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis 34 c3ffsC_ not modelled 54.6 22 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 35 d1brwa2 not modelled 54.3 27 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 36 c1ypfB_ not modelled 51.0 20 PDB header:oxidoreductase Chain: B: PDB Molecule:gmp reductase; PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution 37 c3ggsA_ not modelled 49.3 23 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: human purine nucleoside phosphorylase double mutant e201q,n243d2 complexed with 2-fluoro-2'-deoxyadenosine 38 d1t9ba1 not modelled 47.9 28 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 39 d1f0ka_ not modelled 47.7 16 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Peptidoglycan biosynthesis glycosyltransferase MurG 40 c1yadD_ not modelled 47.6 24 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 41 d2ihta1 not modelled 47.1 24 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 42 c3cf4G_ not modelled 45.1 15 PDB header:oxidoreductase Chain: G: PDB Molecule:acetyl-coa decarboxylase/synthase epsilon subunit; PDBTitle: structure of the codh component of the m. barkeri acds complex 43 c2bibA_ not modelled 45.1 17 PDB header:hydrolase Chain: A: PDB Molecule:teichoic acid phosphorylcholine esterase/ choline binding PDBTitle: crystal structure of the complete modular teichioic acid2 phosphorylcholine esterase pce (cbpe) from streptococcus3 pneumoniae 44 d1xm3a_ not modelled 45.0 16 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 45 d1khda2 not modelled 44.9 21 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 46 c1jvnB_ not modelled 43.8 21 PDB header:transferase Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf; PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites 47 c3mioA_ not modelled 42.0 22 PDB header:lyase Chain: A: PDB Molecule:3,4-dihydroxy-2-butanone 4-phosphate synthase; PDBTitle: crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase2 domain from mycobacterium tuberculosis at ph 6.00 48 d3bgsa1 not modelled 41.1 24 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 49 d1ujqa_ not modelled 40.0 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 50 d3pnpa_ not modelled 39.7 20 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 51 d1zpda1 not modelled 39.2 5 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 52 c3guzB_ not modelled 37.8 26 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's 53 c2qr6A_ not modelled 37.6 20 PDB header:oxidoreductase Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase; PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution 54 c2agkA_ not modelled 37.0 16 PDB header:isomerase Chain: A: PDB Molecule:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) PDBTitle: structure of s. cerevisiae his6 protein 55 d1h5ya_ not modelled 36.1 21 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 56 c1jd7A_ not modelled 35.0 16 PDB header:hydrolase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: crystal structure analysis of the mutant k300r of2 pseudoalteromonas haloplanctis alpha-amylase 57 d1wdia_ not modelled 34.9 27 Fold:QueA-like Superfamily:QueA-like Family:QueA-like 58 c2qmoA_ not modelled 34.5 14 PDB header:ligase Chain: A: PDB Molecule:dethiobiotin synthetase; PDBTitle: crystal structure of dethiobiotin synthetase (biod) from helicobacter2 pylori 59 d1n57a_ not modelled 34.4 33 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:DJ-1/PfpI 60 d2ae2a_ not modelled 34.2 22 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 61 d1v77a_ not modelled 33.9 10 Fold:7-stranded beta/alpha barrel Superfamily:PHP domain-like Family:RNase P subunit p30 62 c2yvqA_ not modelled 33.5 58 PDB header:ligase Chain: A: PDB Molecule:carbamoyl-phosphate synthase; PDBTitle: crystal structure of mgs domain of carbamoyl-phosphate2 synthetase from homo sapiens 63 c3eooL_ not modelled 33.4 17 PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei 64 c2xvzA_ not modelled 32.8 11 PDB header:metal binding protein Chain: A: PDB Molecule:chelatase, putative; PDBTitle: cobalt chelatase cbik (periplasmatic) from desulvobrio2 vulgaris hildenborough (co-crystallized with cobalt) 65 c3rggD_ not modelled 32.6 23 PDB header:lyase Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase, pure protein; PDBTitle: crystal structure of treponema denticola pure bound to air 66 c3chvA_ not modelled 32.0 19 PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution 67 c3n6rK_ not modelled 31.5 22 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 68 c3nxkE_ not modelled 31.2 22 PDB header:hydrolase Chain: E: PDB Molecule:cytoplasmic l-asparaginase; PDBTitle: crystal structure of probable cytoplasmic l-asparaginase from2 campylobacter jejuni 69 c3e02A_ not modelled 29.8 23 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849; PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution 70 d1u11a_ not modelled 29.6 10 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 71 c3b40A_ not modelled 29.5 21 PDB header:hydrolase Chain: A: PDB Molecule:probable dipeptidase; PDBTitle: crystal structure of the probable dipeptidase pvdm from2 pseudomonas aeruginosa 72 d1ebda3 not modelled 28.5 16 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 73 c2a7rD_ not modelled 27.2 15 PDB header:oxidoreductase Chain: D: PDB Molecule:gmp reductase 2; PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2) 74 c3nzqB_ not modelled 27.2 17 PDB header:lyase Chain: B: PDB Molecule:biosynthetic arginine decarboxylase; PDBTitle: crystal structure of biosynthetic arginine decarboxylase adc (spea)2 from escherichia coli, northeast structural genomics consortium3 target er600 75 c2fw9A_ not modelled 26.5 10 PDB header:lyase Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: structure of pure (n5-carboxyaminoimidazole ribonucleotide mutase)2 h59f from the acidophilic bacterium acetobacter aceti, at ph 8 76 c2vedA_ not modelled 25.7 21 PDB header:transferase Chain: A: PDB Molecule:membrane protein capa1, protein tyrosine kinase; PDBTitle: crystal structure of the chimerical mutant capabk55m2 protein 77 d2tpta2 not modelled 25.2 21 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 78 d1g2oa_ not modelled 24.6 24 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 79 d2ji7a1 not modelled 24.5 23 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 80 c3e49A_ not modelled 24.0 19 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849 with a tim barrel fold; PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb4003 at 1.75 a resolution 81 d1ovma1 not modelled 23.2 6 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 82 d1q6za1 not modelled 22.9 14 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 83 c3majA_ not modelled 22.8 21 PDB header:dna binding protein Chain: A: PDB Molecule:dna processing chain a; PDBTitle: crystal structure of putative dna processing protein dpra from2 rhodopseudomonas palustris cga009 84 d1wmaa1 not modelled 22.6 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 85 c1a31A_ not modelled 22.6 14 PDB header:isomerase/dna Chain: A: PDB Molecule:protein (topoisomerase i); PDBTitle: human reconstituted dna topoisomerase i in covalent complex2 with a 22 base pair dna duplex 86 c3ceuA_ not modelled 22.6 23 PDB header:transferase Chain: A: PDB Molecule:thiamine phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamine phosphate pyrophosphorylase2 (bt_0647) from bacteroides thetaiotaomicron. northeast3 structural genomics consortium target btr268 87 d2adra2 not modelled 22.4 28 Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2 88 d1v58a2 not modelled 22.3 22 Fold:Cystatin-like Superfamily:DsbC/DsbG N-terminal domain-like Family:DsbC/DsbG N-terminal domain-like 89 d3grsa3 not modelled 22.3 20 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 90 c3oixA_ not modelled 22.2 16 PDB header:oxidoreductase Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans 91 d1vrda1 not modelled 22.1 20 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 92 c1mg7B_ not modelled 21.9 21 PDB header:gene regulation Chain: B: PDB Molecule:early switch protein xol-1 2.2k splice form; PDBTitle: crystal structure of xol-1 93 d1k4ia_ not modelled 21.8 23 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 94 d1pkla2 not modelled 21.7 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 95 c3o2sB_ not modelled 21.6 33 PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72 complex 96 c3o2qB_ not modelled 21.5 30 PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72-ctd phosphopeptide2 complex 97 d1ozha1 not modelled 21.3 20 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 98 d1wraa1 not modelled 21.0 13 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Pce catalytic domain-like 99 d2dasa1 not modelled 20.9 32 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:TRASH domain 100 d1j6ua1 not modelled 20.8 12 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 101 c2dasA_ not modelled 20.6 32 PDB header:metal transport Chain: A: PDB Molecule:zinc finger mym-type protein 5; PDBTitle: solution structure of trash domain of zinc finger mym-type2 protein 5 102 c3labA_ not modelled 20.5 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 103 c3lu2B_ not modelled 20.4 19 PDB header:hydrolase Chain: B: PDB Molecule:lmo2462 protein; PDBTitle: structure of lmo2462, a listeria monocytogenes amidohydrolase family2 putative dipeptidase 104 d1o17a2 not modelled 20.4 18 Fold:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Family:Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 105 d1aoga3 not modelled 20.3 18 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 106 c3tovB_ not modelled 20.1 14 PDB header:transferase Chain: B: PDB Molecule:glycosyl transferase family 9; PDBTitle: the crystal structure of the glycosyl transferase family 9 from2 veillonella parvula dsm 2008 107 d1tksa_ not modelled 20.1 21 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0