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  Protein Homology/analogY Recognition Engine V 2.2
 

Fold library entry viewer: c1a31A_

Fold library idPDB HeaderMoleculeTitle
c1a31A_PDB header: isomerase/dnaChain: A: PDB Molecule: protein (topoisomerase i);PDBTitle: human reconstituted dna topoisomerase i in covalent complex2 with a 22 base pair dna duplex


Added to library: Tue Mar 16 12:29:48 2010
 
Links to external resources


 1........10.........20.........30.........40.........50.........60.........70
Sequence IKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRK
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Known secondary structure (DSSP)


S



B








TT


TT



TTTTSGGGG
 .........80.........90.........100.........110.........120.........130.........140
Sequence EMTNEEKNIITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLKIKEENEKLLKEYGFCIMDNHKERIANFK
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Known secondary structure (DSSP) S



GGG
S

STTBS

B
 .........150.........160.........170.........180.........190.........200.........210
Sequence IEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSI
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Known secondary structure (DSSP)


S


SSS
TTTT




GGG


TTS




STT


S

TTS

S
TTT

 .........220.........230.........240.........250.........260.........270.........280
Sequence KYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKE
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Known secondary structure (DSSP)
B
TTSTT
S









 .........290.........300.........310.........320.........330.........340.........350
Sequence EGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDL
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Known secondary structure (DSSP) TTTS




GGG
BGGG

TT
GGG


TTTT

TTSBT
 .........360.........370.........380.........390.........400.........410.........420
Sequence FDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVKLNLDPRI
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Known secondary structure (DSSP) TTT

STT



TT







 .........430.........440.........450.......
Sequence TVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF
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Known secondary structure (DSSP) TT

GGGTS
T

TT



Download:PDB structure FASTA sequence

Hidden Markov model

Image coloured by rainbow N → C terminus
Interactive 3D view in JSmol


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Accessibility Statement
Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction
Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960
 
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Michael Sternberg  
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