Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP31666
DateThu Jan 5 11:48:29 GMT 2012
Unique Job IDeda3e1311e20fe7b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2j13a1
Top template information
Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
Confidence and coverage
Confidence: 99.9% Coverage: 41%
169 residues ( 41% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
347 residues ( 85%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVTVGNIRAGQIIAVEPTA
Secondary structure 
SS confidence 
Disorder  ?????
??????
??
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  ASYYAFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSNQNLVTWKDTPVYNAPSAG
Secondary structure 
SS confidence 
Disorder 
?
??????????????
??
?
?
?
??
????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  SAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYISALDAQPDNGLSVLTYHHILR
Secondary structure 
SS confidence 
Disorder  ??
??????????????????????
?
???
??
?
????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  DEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMVQLEGYVKNKINLPARAVVITFDD
Secondary structure 
SS confidence 
Disorder 
?
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  GLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKWNPKSLQFMSVSELNEIRDVFDFQS
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  HTHFLHRVDGYRRPILLSRSEHNILFDFARSRRALAQFNPHVWYLSYPFGGFNDNAVKAA
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 
   .........370.........380.........390.........400.........
Sequence  NDAGFHLAVTTMKGKVKPGDNPLLLKRLYILRTDSLETMSRLVSNQPQG
Secondary structure 
SS confidence 
Disorder 
??
??????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2j13 chain A domain 1

3D model

Region: 209 - 403
Aligned: 169
Modelled: 195
Confidence: 99.9%
Identity: 20%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: NodB-like polysaccharide deacetylase

Phyre2

PDB 2iw0 chain A domain 1

3D model

Region: 227 - 368
Aligned: 126
Modelled: 142
Confidence: 99.9%
Identity: 21%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: NodB-like polysaccharide deacetylase

Phyre2

PDB 2cc0 chain A domain 1

3D model

Region: 231 - 367
Aligned: 116
Modelled: 137
Confidence: 99.9%
Identity: 22%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: NodB-like polysaccharide deacetylase

Phyre2

PDB 1w17 chain A

3D model

Region: 226 - 368
Aligned: 122
Modelled: 143
Confidence: 99.9%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:probable polysaccharide deacetylase pdaa;
PDBTitle: structure of bacillus subtilis pdaa, a family 42 carbohydrate esterase.

Phyre2

PDB 2iw0 chain A

3D model

Region: 230 - 368
Aligned: 123
Modelled: 139
Confidence: 99.9%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:chitin deacetylase;
PDBTitle: structure of the chitin deacetylase from the fungal2 pathogen colletotrichum lindemuthianum

Phyre2

PDB 2c1i chain A

3D model

Region: 214 - 368
Aligned: 131
Modelled: 155
Confidence: 99.9%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:peptidoglycan glcnac deacetylase;
PDBTitle: structure of streptococcus pnemoniae peptidoglycan2 deacetylase (sppgda) d 275 n mutant.

Phyre2

PDB 1ny1 chain A

3D model

Region: 226 - 368
Aligned: 122
Modelled: 143
Confidence: 99.9%
Identity: 21%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: NodB-like polysaccharide deacetylase

Phyre2

PDB 2w3z chain A

3D model

Region: 213 - 380
Aligned: 148
Modelled: 153
Confidence: 99.9%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:putative deacetylase;
PDBTitle: structure of a streptococcus mutans ce4 esterase

Phyre2

PDB 2vyo chain A

3D model

Region: 231 - 368
Aligned: 121
Modelled: 127
Confidence: 99.9%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:chitooligosaccharide deacetylase;
PDBTitle: chitin deacetylase family member from encephalitozoon2 cuniculi

Phyre2

PDB 2c1i chain A domain 1

3D model

Region: 232 - 365
Aligned: 113
Modelled: 134
Confidence: 99.8%
Identity: 20%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: NodB-like polysaccharide deacetylase

Phyre2

PDB 2c71 chain A domain 1

3D model

Region: 232 - 365
Aligned: 114
Modelled: 122
Confidence: 99.8%
Identity: 18%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: NodB-like polysaccharide deacetylase

Phyre2

PDB 3rxz chain A

3D model

Region: 230 - 374
Aligned: 124
Modelled: 141
Confidence: 99.7%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:polysaccharide deacetylase;
PDBTitle: crystal structure of putative polysaccharide deacetylase from2 mycobacterium smegmatis

Phyre2

PDB 3npf chain B

3D model

Region: 22 - 168
Aligned: 134
Modelled: 147
Confidence: 99.6%
Identity: 18%
PDB header:hydrolase
Chain: B: PDB Molecule:putative dipeptidyl-peptidase vi;
PDBTitle: crystal structure of a putative dipeptidyl-peptidase vi (bacova_00612)2 from bacteroides ovatus at 1.72 a resolution

Phyre2

PDB 3qbu chain D

3D model

Region: 233 - 378
Aligned: 125
Modelled: 146
Confidence: 99.6%
Identity: 20%
PDB header:hydrolase
Chain: D: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of putative peptidoglyacn deactelyase (hp0310) from2 helicobacter pylori

Phyre2

PDB 1xov chain A

3D model

Region: 27 - 167
Aligned: 129
Modelled: 140
Confidence: 99.6%
Identity: 10%
PDB header:hydrolase
Chain: A: PDB Molecule:ply protein;
PDBTitle: the crystal structure of the listeria monocytogenes bacteriophage psa2 endolysin plypsa

Phyre2

PDB 1z7a chain A domain 1

3D model

Region: 228 - 374
Aligned: 126
Modelled: 147
Confidence: 99.5%
Identity: 14%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: PA1517-like

Phyre2

PDB 3s6o chain D

3D model

Region: 225 - 374
Aligned: 128
Modelled: 150
Confidence: 99.5%
Identity: 13%
PDB header:hydrolase
Chain: D: PDB Molecule:polysaccharide deacetylase family protein;
PDBTitle: crystal structure of a polysaccharide deacetylase family protein from2 burkholderia pseudomallei

Phyre2

PDB 2nly chain A domain 1

3D model

Region: 232 - 369
Aligned: 117
Modelled: 124
Confidence: 99.4%
Identity: 10%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: Divergent polysaccharide deacetylase

Phyre2

PDB 2krs chain A

3D model

Region: 26 - 93
Aligned: 68
Modelled: 68
Confidence: 99.2%
Identity: 12%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:probable enterotoxin;
PDBTitle: solution nmr structure of sh3 domain from cpf_0587 (fragment2 415-479) from clostridium perfringens. northeast structural3 genomics consortium (nesg) target cpr74a.

Phyre2

PDB 2kt8 chain A

3D model

Region: 20 - 90
Aligned: 71
Modelled: 71
Confidence: 99.2%
Identity: 8%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:probable surface protein;
PDBTitle: solution nmr structure of the cpe1231(468-535) protein from2 clostridium perfringens, northeast structural genomics3 consortium target cpr82b

Phyre2

PDB 3m1u chain B

3D model

Region: 23 - 203
Aligned: 155
Modelled: 149
Confidence: 97.7%
Identity: 17%
PDB header:hydrolase
Chain: B: PDB Molecule:putative gamma-d-glutamyl-l-diamino acid endopeptidase;
PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (dvu_0896) from desulfovibrio vulgaris hildenborough at3 1.75 a resolution

Phyre2
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d2j13a1
2
d2iw0a1
3
d2cc0a1
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c1w17A_
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c2iw0A_
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c2c1iA_
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d1ny1a_
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c2w3zA_
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c2vyoA_
10
d2c1ia1
11
d2c71a1
12
c3rxzA_
13
c3npfB_
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c3qbuD_
15
c1xovA_
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d1z7aa1
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c3s6oD_
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d2nlya1
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c2krsA_
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c2kt8A_
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c3m1uB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2j13a1
99.9 20 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
2d2iw0a1
99.9 21 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
3d2cc0a1
99.9 22 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
4c1w17A_
99.9 21 PDB header:hydrolase
Chain: A: PDB Molecule:probable polysaccharide deacetylase pdaa;
PDBTitle: structure of bacillus subtilis pdaa, a family 42 carbohydrate esterase.
5c2iw0A_
99.9 21 PDB header:hydrolase
Chain: A: PDB Molecule:chitin deacetylase;
PDBTitle: structure of the chitin deacetylase from the fungal2 pathogen colletotrichum lindemuthianum
6c2c1iA_
99.9 20 PDB header:hydrolase
Chain: A: PDB Molecule:peptidoglycan glcnac deacetylase;
PDBTitle: structure of streptococcus pnemoniae peptidoglycan2 deacetylase (sppgda) d 275 n mutant.
7d1ny1a_
99.9 21 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
8c2w3zA_
99.9 23 PDB header:hydrolase
Chain: A: PDB Molecule:putative deacetylase;
PDBTitle: structure of a streptococcus mutans ce4 esterase
9c2vyoA_
99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:chitooligosaccharide deacetylase;
PDBTitle: chitin deacetylase family member from encephalitozoon2 cuniculi
10d2c1ia1
99.8 20 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
11d2c71a1
99.8 18 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
12c3rxzA_
99.7 24 PDB header:hydrolase
Chain: A: PDB Molecule:polysaccharide deacetylase;
PDBTitle: crystal structure of putative polysaccharide deacetylase from2 mycobacterium smegmatis
13c3npfB_
99.6 18 PDB header:hydrolase
Chain: B: PDB Molecule:putative dipeptidyl-peptidase vi;
PDBTitle: crystal structure of a putative dipeptidyl-peptidase vi (bacova_00612)2 from bacteroides ovatus at 1.72 a resolution
14c3qbuD_
99.6 20 PDB header:hydrolase
Chain: D: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of putative peptidoglyacn deactelyase (hp0310) from2 helicobacter pylori
15c1xovA_
99.6 10 PDB header:hydrolase
Chain: A: PDB Molecule:ply protein;
PDBTitle: the crystal structure of the listeria monocytogenes bacteriophage psa2 endolysin plypsa
16d1z7aa1
99.5 14 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:PA1517-like
17c3s6oD_
99.5 13 PDB header:hydrolase
Chain: D: PDB Molecule:polysaccharide deacetylase family protein;
PDBTitle: crystal structure of a polysaccharide deacetylase family protein from2 burkholderia pseudomallei
18d2nlya1
99.4 10 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:Divergent polysaccharide deacetylase
19c2krsA_
99.2 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:probable enterotoxin;
PDBTitle: solution nmr structure of sh3 domain from cpf_0587 (fragment2 415-479) from clostridium perfringens. northeast structural3 genomics consortium (nesg) target cpr74a.
20c2kt8A_
99.2 8 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:probable surface protein;
PDBTitle: solution nmr structure of the cpe1231(468-535) protein from2 clostridium perfringens, northeast structural genomics3 consortium target cpr82b
21c3h41A_
not modelled 99.1 18 PDB header:hydrolase
Chain: A: PDB Molecule:nlp/p60 family protein;
PDBTitle: crystal structure of a nlpc/p60 family protein (bce_2878) from2 bacillus cereus atcc 10987 at 1.79 a resolution
22c2kq8A_
not modelled 99.1 13 PDB header:hydrolase
Chain: A: PDB Molecule:cell wall hydrolase;
PDBTitle: solution nmr structure of a domain from bt9727_4915 from2 bacillus thuringiensis, northeast structural genomics3 consortium target bur95a
23c2kybA_
not modelled 99.0 17 PDB header:toxin
Chain: A: PDB Molecule:mannosyl-glycoprotein endo-beta-n-acetylglucosamidase
PDBTitle: solution structure of cpr82g from clostridium perfringens. north east2 structural genomics consortium target cpr82g
24c1ng2A_
not modelled 99.0 18 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
25c1m9sA_
not modelled 98.8 21 PDB header:signaling protein
Chain: A: PDB Molecule:internalin b;
PDBTitle: crystal structure of internalin b (inlb), a listeria2 monocytogenes virulence protein containing sh3-like3 domains.
26c1ov3A_
not modelled 98.7 18 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
27c1griA_
not modelled 98.4 18 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
28c2eyzA_
not modelled 98.1 11 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
29d1k1xa3
not modelled 98.0 13 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:4-alpha-glucanotransferase, N-terminal domain
30c2l3sA_
not modelled 97.7 13 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
31c3m1uB_
97.7 17 PDB header:hydrolase
Chain: B: PDB Molecule:putative gamma-d-glutamyl-l-diamino acid endopeptidase;
PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (dvu_0896) from desulfovibrio vulgaris hildenborough at3 1.75 a resolution
32c1k1yA_
not modelled 97.4 13 PDB header:transferase
Chain: A: PDB Molecule:4-alpha-glucanotransferase;
PDBTitle: crystal structure of thermococcus litoralis 4-alpha-glucanotransferase2 complexed with acarbose
33d2b5dx2
not modelled 96.5 5 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:AmyC N-terminal domain-like
34c2ed0A_
not modelled 96.4 20 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
35c2pqhA_
not modelled 96.3 11 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal
36c2yuoA_
not modelled 96.2 13 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
37c2dbmA_
not modelled 96.1 16 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:sh3-containing grb2-like protein 2;
PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2
38c2eyyA_
not modelled 96.1 14 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
39c2ekhA_
not modelled 96.1 17 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
40c2dmoA_
not modelled 96.0 20 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
41c2nwmA_
not modelled 96.0 8 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
42c2b5dX_
not modelled 95.9 6 PDB header:hydrolase
Chain: X: PDB Molecule:alpha-amylase;
PDBTitle: crystal structure of the novel alpha-amylase amyc from thermotoga2 maritima
43d1tuca_
not modelled 95.9 11 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
44d1utia_
not modelled 95.9 14 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
45d1sema_
not modelled 95.8 10 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
46c2djqA_
not modelled 95.7 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
47d1gria2
not modelled 95.7 17 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
48d1ng2a2
not modelled 95.7 7 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
49d1oeba_
not modelled 95.7 16 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
50d1ug1a_
not modelled 95.7 19 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
51d1wfwa_
not modelled 95.6 13 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
52c2df6A_
not modelled 95.6 10 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
53c2dbkA_
not modelled 95.6 16 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
54d1ov3a2
not modelled 95.6 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
55c1x2pA_
not modelled 95.6 15 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 2;
PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
56c2kbtA_
not modelled 95.6 12 PDB header:signaling protein
Chain: A: PDB Molecule:chimera of proto-oncogene vav, linker,
PDBTitle: attachment of an nmr-invisible solubility enhancement tag2 (inset) using a sortase-mediated protein ligation method
57c1r77A_
not modelled 95.6 16 PDB header:hydrolase
Chain: A: PDB Molecule:cell wall targeting domain of glycylglycine
PDBTitle: crystal structure of the cell wall targeting domain of2 peptidylglycan hydrolase ale-1
58c1wyxA_
not modelled 95.6 16 PDB header:cell adhesion
Chain: A: PDB Molecule:crk-associated substrate;
PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
59c2dl3A_
not modelled 95.5 13 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
60c2drmB_
not modelled 95.5 12 PDB header:contractile protein
Chain: B: PDB Molecule:acanthamoeba myosin ib;
PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
61d1udla_
not modelled 95.4 12 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
62d1uhfa_
not modelled 95.3 14 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
63d1uj0a_
not modelled 95.3 11 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
64c2j6kE_
not modelled 95.3 11 PDB header:protein binding
Chain: E: PDB Molecule:cd2-associated protein;
PDBTitle: n-terminal sh3 domain of cms (cd2ap human homolog)
65c2csqA_
not modelled 95.3 10 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
66d1nega_
not modelled 95.3 9 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
67c1negA_
not modelled 95.3 9 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin
68d1oota_
not modelled 95.3 15 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
69d1uuea_
not modelled 95.2 14 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
70c2dilA_
not modelled 95.2 21 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
71d1gcqa_
not modelled 95.2 18 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
72d1pwta_
not modelled 95.2 12 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
73c2yunA_
not modelled 95.2 11 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
74c1zx6A_
not modelled 95.2 24 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
75d1uffa_
not modelled 95.1 12 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
76d1u06a1
not modelled 95.1 12 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
77c2dl4A_
not modelled 95.0 17 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
78d1gl5a_
not modelled 95.0 9 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
79c2d1xD_
not modelled 95.0 11 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
80c1w70A_
not modelled 95.0 5 PDB header:sh3 domain
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
81c2dnuA_
not modelled 95.0 9 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
82c2krnA_
not modelled 94.9 8 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: high resolution structure of the second sh3 domain of cd2ap
83c1zlmA_
not modelled 94.9 11 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
84c1wi7A_
not modelled 94.9 11 PDB header:protein binding
Chain: A: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: solution structure of the sh3 domain of sh3-domain kinase2 binding protein 1
85d1gbra_
not modelled 94.8 17 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
86d1k4us_
not modelled 94.8 15 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
87c2k6dA_
not modelled 94.8 8 PDB header:sh3 domain/ubiquitin
Chain: A: PDB Molecule:sh3 domain-containing kinase-binding protein 1;
PDBTitle: cin85 sh3-c domain in complex with ubiquitin
88c1x2qA_
not modelled 94.8 13 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
89c2epdA_
not modelled 94.8 19 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
90c2xmfA_
not modelled 94.8 11 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
91d1wlpb2
not modelled 94.8 16 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
92c2ebpA_
not modelled 94.8 9 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
93c2jxbA_
not modelled 94.7 13 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
94c2dl8A_
not modelled 94.7 7 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
95c2fg0B_
not modelled 94.7 11 PDB header:hydrolase
Chain: B: PDB Molecule:cog0791: cell wall-associated hydrolases (invasion-
PDBTitle: crystal structure of a putative gamma-d-glutamyl-l-diamino acid2 endopeptidase (npun_r0659) from nostoc punctiforme pcc 73102 at 1.793 a resolution
96c2azsA_
not modelled 94.7 18 PDB header:signaling protein
Chain: A: PDB Molecule:sh2-sh3 adapter protein drk;
PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints)
97c2ysqA_
not modelled 94.6 12 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
98c2dx1A_
not modelled 94.6 16 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
99c2a28D_
not modelled 94.6 3 PDB header:signaling protein
Chain: D: PDB Molecule:bzz1 protein;
PDBTitle: atomic-resolution crystal structure of the second sh32 domain of yeast bzz1 determined from a pseudomerohedrally3 twinned crystal
100c2dlpA_
not modelled 94.6 16 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
101c1z9qA_
not modelled 94.5 13 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: solution structure of sh3 domain of p40phox
102d1opka1
not modelled 94.5 11 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
103c2eyxA_
not modelled 94.5 10 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
104c2cubA_
not modelled 94.5 6 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
105c1x69A_
not modelled 94.4 12 PDB header:signaling protein
Chain: A: PDB Molecule:cortactin isoform a;
PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin
106d1ujya_
not modelled 94.4 13 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
107d1e6ga_
not modelled 94.3 16 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
108c2ed1A_
not modelled 94.3 12 PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
109c2egaA_
not modelled 94.3 14 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein
110c2dybA_
not modelled 94.3 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: the crystal structure of human p40(phox)
111d1e6ha_
not modelled 94.3 16 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
112c2csiA_
not modelled 94.2 26 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the third sh3 domain of human rim-2 binding protein 2
113d1ov3a1
not modelled 94.2 16 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
114c2bz8B_
not modelled 94.2 13 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
115c2js0A_
not modelled 94.2 10 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of second sh3 domain of adaptor nck
116d2fo0a1
not modelled 94.1 11 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
117d1j3ta_
not modelled 93.9 17 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
118c1x43A_
not modelled 93.9 14 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
119c2l0aA_
not modelled 93.9 8 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
120d1lcka1
not modelled 93.9 11 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0