Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	Q	I	N	S	N	K	K	H	S	N	R	R	K	Y	F	S	L	L	A	V	V	L	F	I	A	F	S	G	A	Y	A	Y	W	S	M	E	L	E	D	M	I	S	T	D	D	A	Y	V	T	G	N	A	D	P	I	S	A	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																								?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	S	G	S	V	T	V	V	N	H	K	D	T	N	Y	V	R	Q	G	D	I	L	V	S	L	D	K	T	D	A	T	I	A	L	N	K	A	K	N	N	L	A	N	I	V	R	Q	T	N	K	L	Y	L	Q	D	K	Q	Y	S	A
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	V	A	S	A	R	I	Q	Y	Q	Q	S	L	E	D	Y	N	R	R	V	P	L	A	K	Q	G	V	I	S	K	E	T	L	E	H	T	K	D	T	L	I	S	S	K	A	A	L	N	A	A	I	Q	A	Y	K	A	N	K	A	L
Secondary structure
SS confidence
Disorder																										?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	M	N	T	P	L	N	R	Q	P	Q	V	V	E	A	A	D	A	T	K	E	A	W	L	A	L	K	R	T	D	I	K	S	P	V	T	G	Y	I	A	Q	R	S	V	Q	V	G	E	T	V	S	P	G	Q	S	L	M	A	V	V
Secondary structure
SS confidence
Disorder		?	?																																														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	A	R	Q	M	W	V	N	A	N	F	K	E	T	Q	L	T	D	V	R	I	G	Q	S	V	N	I	I	S	D	L	Y	G	E	N	V	V	F	H	G	R	V	T	G	I	N	M	G	T	G	N	A	F	S	L	L	P	A	Q	N
Secondary structure
SS confidence
Disorder																				?	?																											?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	T	G	N	W	I	K	I	V	Q	R	V	P	V	E	V	S	L	D	P	K	E	L	M	E	H	P	L	R	I	G	L	S	M	T	A	T	I	D	T	K	N	E	D	I	A	E	M	P	E	L	A	S	T	V	T	S	M	P	A
Secondary structure
SS confidence
Disorder		?																					?	?	?	?	?	?																		?					?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.
Sequence		Y	T	S	K	A	L	V	I	D	T	S	P	I	E	K	E	I	S	N	I	I	S	H	N	G	Q	L
Secondary structure
SS confidence
Disorder		?											?										?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3fpp chain B Region: 41 - 347 Aligned: 257 Modelled: 261 Confidence: 100.0% Identity: 18% PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca Phyre2 PDB 3h9i chain B Region: 41 - 386 Aligned: 255 Modelled: 255 Confidence: 100.0% Identity: 15% PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli Phyre2 PDB 2f1m chain A Region: 47 - 338 Aligned: 221 Modelled: 230 Confidence: 99.9% Identity: 23% PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra Phyre2 PDB 3lnn chain B Region: 39 - 341 Aligned: 241 Modelled: 246 Confidence: 99.9% Identity: 21% PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans Phyre2 PDB 1t5e chain B Region: 47 - 338 Aligned: 212 Modelled: 216 Confidence: 99.9% Identity: 21% PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa Phyre2 PDB 1vf7 chain A Region: 41 - 341 Aligned: 221 Modelled: 225 Confidence: 99.9% Identity: 21% Fold: HlyD-like secretion proteins Superfamily: HlyD-like secretion proteins Family: HlyD-like secretion proteins Phyre2 PDB 2k33 chain A Region: 55 - 255 Aligned: 113 Modelled: 113 Confidence: 99.6% Identity: 27% PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation Phyre2 PDB 2b8g chain A Region: 56 - 244 Aligned: 72 Modelled: 72 Confidence: 98.6% Identity: 21% PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) Phyre2 PDB 3n6r chain K Region: 56 - 239 Aligned: 67 Modelled: 67 Confidence: 98.5% Identity: 42% PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) Phyre2 PDB 1dcz chain A Region: 56 - 239 Aligned: 67 Modelled: 67 Confidence: 98.5% Identity: 54% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2ejg chain D Region: 56 - 239 Aligned: 67 Modelled: 67 Confidence: 98.4% Identity: 33% PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 Phyre2 PDB 1o78 chain A Region: 57 - 239 Aligned: 66 Modelled: 66 Confidence: 98.3% Identity: 27% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2ejm chain A Region: 57 - 244 Aligned: 71 Modelled: 71 Confidence: 98.3% Identity: 48% PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase Phyre2 PDB 2dn8 chain A Region: 56 - 243 Aligned: 70 Modelled: 71 Confidence: 98.1% Identity: 13% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase Phyre2 PDB 2kcc chain A Region: 50 - 244 Aligned: 77 Modelled: 78 Confidence: 98.0% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 Phyre2 PDB 1qjo chain A Region: 62 - 244 Aligned: 66 Modelled: 66 Confidence: 98.0% Identity: 23% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1iyu chain A Region: 63 - 244 Aligned: 65 Modelled: 65 Confidence: 97.9% Identity: 34% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1k8m chain A Region: 62 - 244 Aligned: 66 Modelled: 66 Confidence: 97.9% Identity: 26% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1bdo chain A Region: 56 - 239 Aligned: 67 Modelled: 67 Confidence: 97.9% Identity: 18% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1ghj chain A Region: 59 - 243 Aligned: 68 Modelled: 68 Confidence: 97.9% Identity: 29% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 3fmc chain C Region: 18 - 89 Aligned: 71 Modelled: 68 Confidence: 88.7% Identity: 17% PDB header:hydrolase Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase; PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution Phyre2 1 c3fppB_ 2 c3h9iB_ 3 c2f1mA_ 4 c3lnnB_ 5 c1t5eB_ 6 d1vf7a_ 7 c2k33A_ 8 c2b8gA_ 9 c3n6rK_ 10 d1dcza_ 11 c2ejgD_ 12 d1o78a_ 13 c2ejmA_ 14 c2dn8A_ 15 c2kccA_ 16 d1qjoa_ 17 d1iyua_ 18 d1k8ma_ 19 d1bdoa_ 20 d1ghja_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 c3fmcC_ 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3fppB_ 100.0 18 PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca 2 c3h9iB_ 100.0 15 PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli 3 c2f1mA_ 99.9 23 PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra 4 c3lnnB_ 99.9 21 PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans 5 c1t5eB_ 99.9 21 PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa 6 d1vf7a_ 99.9 21 Fold:HlyD-like secretion proteins Superfamily:HlyD-like secretion proteins Family:HlyD-like secretion proteins 7 c2k33A_ 99.6 27 PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation 8 c2b8gA_ 98.6 21 PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) 9 c3n6rK_ 98.5 42 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 10 d1dcza_ 98.5 54 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 11 c2ejgD_ 98.4 33 PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 12 d1o78a_ 98.3 27 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 13 c2ejmA_ 98.3 48 PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase 14 c2dn8A_ 98.1 13 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase 15 c2kccA_ 98.0 19 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 16 d1qjoa_ 98.0 23 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 17 d1iyua_ 97.9 34 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 18 d1k8ma_ 97.9 26 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 19 d1bdoa_ 97.9 18 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 20 d1ghja_ 97.9 29 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 21 c2q8iB_ not modelled 97.8 52 PDB header:transferase Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol 22 c2l5tA_ not modelled 97.7 38 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum 23 d1y8ob1 not modelled 97.7 52 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 24 c2dncA_ not modelled 97.6 46 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase 25 d1laba_ not modelled 97.5 37 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 26 d1gjxa_ not modelled 97.4 34 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 27 d1pmra_ not modelled 97.3 26 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 28 c2dneA_ not modelled 97.1 48 PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase 29 d1glaf_ not modelled 95.9 24 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 30 d2gpra_ not modelled 95.7 32 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 31 d2f3ga_ not modelled 95.6 20 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 32 d1gpra_ not modelled 95.4 18 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 33 d2pnrc1 not modelled 95.2 21 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 34 c2qf7A_ not modelled 95.0 23 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase protein; PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli 35 c2jkuA_ not modelled 94.7 20 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: crystal structure of the n-terminal region of the biotin2 acceptor domain of human propionyl-coa carboxylase 36 d1uoua3 not modelled 93.3 25 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 37 d1brwa3 not modelled 93.0 31 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 38 d2tpta3 not modelled 92.0 25 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 39 c2dsjA_ not modelled 91.1 36 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 40 c1otpA_ not modelled 90.3 24 PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase 41 c3h5qA_ not modelled 90.2 41 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus 42 c2j0fC_ not modelled 90.2 24 PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design 43 c2gu1A_ not modelled 90.2 21 PDB header:hydrolase Chain: A: PDB Molecule:zinc peptidase; PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae 44 c1brwB_ not modelled 88.8 27 PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation 45 c3fmcC_ 88.7 17 PDB header:hydrolase Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase; PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution 46 c2qj8B_ not modelled 87.9 19 PDB header:hydrolase Chain: B: PDB Molecule:mlr6093 protein; PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution 47 c2hsiB_ not modelled 86.1 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative peptidase m23; PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium 48 c2aukA_ not modelled 83.5 20 PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of e. coli rna polymerase beta' g/g' insert 49 c3cdxB_ not modelled 82.4 19 PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides 50 d1qwya_ not modelled 82.4 13 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Peptidoglycan hydrolase LytM 51 c3na6A_ not modelled 81.8 16 PDB header:hydrolase Chain: A: PDB Molecule:succinylglutamate desuccinylase/aspartoacylase; PDBTitle: crystal structure of a succinylglutamate desuccinylase (tm1040_2694)2 from silicibacter sp. tm1040 at 2.00 a resolution 52 d1qpoa2 not modelled 79.2 22 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 53 c2xhaB_ not modelled 75.8 17 PDB header:transcription Chain: B: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of domain 2 of thermotoga maritima n-utilization2 substance g (nusg) 54 c1tqqC_ not modelled 75.5 11 PDB header:transport protein Chain: C: PDB Molecule:outer membrane protein tolc; PDBTitle: structure of tolc in complex with hexamminecobalt 55 d1e2wa2 not modelled 75.2 19 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 56 c2b44A_ not modelled 75.0 13 PDB header:hydrolase Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm; PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form 57 d1wp1a_ not modelled 74.7 11 Fold:Outer membrane efflux proteins (OEP) Superfamily:Outer membrane efflux proteins (OEP) Family:Outer membrane efflux proteins (OEP) 58 d1o4ua2 not modelled 74.4 15 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 59 d1ci3m2 not modelled 73.9 19 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 60 c1yc9A_ not modelled 73.7 9 PDB header:membrane protein Chain: A: PDB Molecule:multidrug resistance protein; PDBTitle: the crystal structure of the outer membrane protein vcec from the2 bacterial pathogen vibrio cholerae at 1.8 resolution 61 d1tova_ not modelled 73.3 16 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 62 d1ek9a_ not modelled 73.1 11 Fold:Outer membrane efflux proteins (OEP) Superfamily:Outer membrane efflux proteins (OEP) Family:Outer membrane efflux proteins (OEP) 63 c3dtpA_ not modelled 73.0 11 PDB header:contractile protein Chain: A: PDB Molecule:myosin 2 heavy chain chimera of smooth and PDBTitle: tarantula heavy meromyosin obtained by flexible docking to2 tarantula muscle thick filament cryo-em 3d-map 64 c3nyyA_ not modelled 72.8 22 PDB header:hydrolase Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm; PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution 65 d1qapa2 not modelled 72.1 10 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 66 c3pikA_ not modelled 71.8 9 PDB header:transport protein Chain: A: PDB Molecule:cation efflux system protein cusc; PDBTitle: outer membrane protein cusc 67 c3it5B_ not modelled 70.6 10 PDB header:hydrolase Chain: B: PDB Molecule:protease lasa; PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa 68 c2xhcA_ not modelled 68.8 17 PDB header:transcription Chain: A: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of thermotoga maritima n-utilization substance g2 (nusg) 69 c2aujD_ not modelled 68.6 31 PDB header:transferase Chain: D: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of thermus aquaticus rna polymerase beta'-subunit2 insert 70 d1ixda_ not modelled 68.5 19 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 71 c3d4rE_ not modelled 67.8 18 PDB header:unknown function Chain: E: PDB Molecule:domain of unknown function from the pfam-b_34464 family; PDBTitle: crystal structure of a duf2118 family protein (mmp0046) from2 methanococcus maripaludis at 2.20 a resolution 72 d1whla_ not modelled 67.6 23 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 73 d2cp2a1 not modelled 66.7 19 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 74 d2coya1 not modelled 66.7 22 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 75 d2cp6a1 not modelled 66.4 21 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 76 d1whma_ not modelled 65.2 17 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 77 d1whga_ not modelled 64.5 16 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 78 c1y4cA_ not modelled 63.4 13 PDB header:de novo protein Chain: A: PDB Molecule:maltose binding protein fused with designed PDBTitle: designed helical protein fusion mbp 79 c3gnnA_ not modelled 62.6 8 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei 80 c3ipkA_ not modelled 62.5 14 PDB header:cell adhesion Chain: A: PDB Molecule:agi/ii; PDBTitle: crystal structure of a3vp1 of agi/ii of streptococcus mutans 81 c1h9mB_ not modelled 62.0 22 PDB header:binding protein Chain: B: PDB Molecule:molybdenum-binding-protein; PDBTitle: two crystal structures of the cytoplasmic molybdate-binding2 protein modg suggest a novel cooperative binding mechanism3 and provide insights into ligand-binding specificity.4 peg-grown form with molybdate bound 82 c3e1yG_ not modelled 61.8 15 PDB header:translation Chain: G: PDB Molecule:eukaryotic peptide chain release factor gtp-binding subunit PDBTitle: crystal structure of human erf1/erf3 complex 83 c2qqsB_ not modelled 61.5 22 PDB header:oxidoreductase Chain: B: PDB Molecule:jmjc domain-containing histone demethylation PDBTitle: jmjd2a tandem tudor domains in complex with a trimethylated2 histone h4-k20 peptide 84 c1o4uA_ not modelled 61.3 15 PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution 85 c3ghgK_ not modelled 58.4 6 PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen 86 d2cp3a1 not modelled 58.2 17 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 87 c1h9sA_ not modelled 58.1 20 PDB header:transcription regulator Chain: A: PDB Molecule:molybdenum transport protein mode; PDBTitle: molybdate bound complex of dimop domain of mode from e.coli 88 c3dlmA_ not modelled 57.9 19 PDB header:transferase Chain: A: PDB Molecule:histone-lysine n-methyltransferase setdb1; PDBTitle: crystal structure of tudor domain of human histone-lysine n-2 methyltransferase setdb1 89 d2ix0a1 not modelled 57.9 12 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 90 c3pajA_ not modelled 57.2 15 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 91 c1qapA_ not modelled 57.1 10 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 92 c1deqF_ not modelled 57.0 9 PDB header: PDB COMPND: 93 d2cp0a1 not modelled 56.6 16 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 94 c1e2vB_ not modelled 56.5 19 PDB header:electron transport proteins Chain: B: PDB Molecule:cytochrome f; PDBTitle: n153q mutant of cytochrome f from chlamydomonas reinhardtii 95 c3m9bK_ not modelled 56.3 12 PDB header:chaperone Chain: K: PDB Molecule:proteasome-associated atpase; PDBTitle: crystal structure of the amino terminal coiled coil domain and the2 inter domain of the mycobacterium tuberculosis proteasomal atpase mpa 96 c3e20A_ not modelled 56.0 17 PDB header:translation Chain: A: PDB Molecule:eukaryotic peptide chain release factor gtp-binding PDBTitle: crystal structure of s.pombe erf1/erf3 complex 97 c1ctmA_ not modelled 56.0 6 PDB header:electron transport(cytochrome) Chain: A: PDB Molecule:cytochrome f; PDBTitle: crystal structure of chloroplast cytochrome f reveals a2 novel cytochrome fold and unexpected heme ligation 98 d1onla_ not modelled 54.6 20 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 99 c2z0wA_ not modelled 54.1 11 PDB header:protein binding Chain: A: PDB Molecule:cap-gly domain-containing linker protein 4; PDBTitle: crystal structure of the 2nd cap-gly domain in human restin-2 like protein 2 reveals a swapped-dimer 100 c2jxmB_ not modelled 53.8 19 PDB header:electron transport Chain: B: PDB Molecule:cytochrome f; PDBTitle: ensemble of twenty structures of the prochlorothrix2 hollandica plastocyanin- cytochrome f complex 101 c3csqC_ not modelled 53.8 12 PDB header:hydrolase Chain: C: PDB Molecule:morphogenesis protein 1; PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail 102 c2jbmA_ not modelled 53.4 0 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human 103 c1zeqX_ not modelled 51.8 15 PDB header:metal binding protein Chain: X: PDB Molecule:cation efflux system protein cusf; PDBTitle: 1.5 a structure of apo-cusf residues 6-88 from escherichia2 coli 104 c2edgA_ not modelled 51.8 16 PDB header:biosynthetic protein Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: solution structure of the gcv_h domain from mouse glycine 105 c2xdpA_ not modelled 51.6 24 PDB header:oxidoreductase Chain: A: PDB Molecule:lysine-specific demethylase 4c; PDBTitle: crystal structure of the tudor domain of human jmjd2c 106 c3tqvA_ not modelled 51.0 12 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis. 107 d2e3ha1 not modelled 50.8 18 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 108 c1tu2B_ not modelled 50.5 25 PDB header:electron transport Chain: B: PDB Molecule:apocytochrome f; PDBTitle: the complex of nostoc cytochrome f and plastocyanin determin with2 paramagnetic nmr. based on the structures of cytochrome f and3 plastocyanin, 10 structures 109 c2e4hA_ not modelled 49.5 18 PDB header:structural protein Chain: A: PDB Molecule:restin; PDBTitle: solution structure of cytoskeletal protein in complex with2 tubulin tail 110 c2b7pA_ not modelled 48.4 25 PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori 111 c1ei3E_ not modelled 46.4 8 PDB header: PDB COMPND: 112 c3l0gD_ not modelled 46.3 20 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 113 c2e75C_ not modelled 46.2 19 PDB header:photosynthesis Chain: C: PDB Molecule:apocytochrome f; PDBTitle: crystal structure of the cytochrome b6f complex with 2-nonyl-4-2 hydroxyquinoline n-oxide (nqno) from m.laminosus 114 d1tu2b2 not modelled 45.5 25 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 115 c2d3eD_ not modelled 45.0 7 PDB header:contractile protein Chain: D: PDB Molecule:general control protein gcn4 and tropomyosin 1 PDBTitle: crystal structure of the c-terminal fragment of rabbit2 skeletal alpha-tropomyosin 116 c3ojaB_ not modelled 43.1 8 PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex 117 c2jvvA_ not modelled 42.9 26 PDB header:transcription Chain: A: PDB Molecule:transcription antitermination protein nusg; PDBTitle: solution structure of e. coli nusg carboxyterminal domain 118 c2kvqG_ not modelled 42.9 26 PDB header:transcription Chain: G: PDB Molecule:transcription antitermination protein nusg; PDBTitle: solution structure of nuse:nusg-ctd complex 119 c1qpoA_ not modelled 41.8 22 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 120 d2hqha1 not modelled 41.3 17 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0