Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	K	P	Y	V	R	L	D	K	N	D	A	A	V	L	L	V	D	H	Q	A	G	L	L	S	L	V	R	D	I	E	P	D	K	F	K	N	N	V	L	A	L	G	D	L	A	K	Y	F	N	L	P	T	I	L	T	T	S	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	T	G	P	N	G	P	L	V	P	E	L	K	A	Q	F	P	D	T	P	Y	I	A	R	P	G	N	I	N	A	W	D	N	E	D	F	V	K	A	V	K	A	T	G	K	K	Q	L	I	I	A	G	V	V	T	E	V	C	V	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	P	A	L	S	A	I	E	E	G	F	D	V	F	V	V	T	D	A	S	G	T	F	N	E	I	T	R	H	S	A	W	D	R	L	S	Q	A	G	A	Q	L	M	T	W	F	G	V	A	C	E	L	H	R	D	W	R	N	D	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.
Sequence		E	G	L	A	T	L	F	S	N	H	I	P	D	Y	R	N	L	M	T	S	Y	D	T	L	T	K	Q	K
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1yac chain A Region: 2 - 205 Aligned: 204 Modelled: 204 Confidence: 100.0% Identity: 98% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 2b34 chain C Region: 7 - 195 Aligned: 183 Modelled: 189 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans Phyre2 PDB 1yzv chain A Region: 2 - 192 Aligned: 185 Modelled: 191 Confidence: 100.0% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: hypothetical protein from trypanosoma cruzi Phyre2 PDB 1x9g chain A Region: 1 - 192 Aligned: 184 Modelled: 192 Confidence: 100.0% Identity: 17% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 2fq1 chain A Region: 2 - 169 Aligned: 166 Modelled: 168 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains Phyre2 PDB 3irv chain A Region: 1 - 176 Aligned: 174 Modelled: 176 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a Phyre2 PDB 1j2r chain A Region: 5 - 172 Aligned: 166 Modelled: 168 Confidence: 100.0% Identity: 17% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 1nba chain A Region: 11 - 179 Aligned: 167 Modelled: 167 Confidence: 100.0% Identity: 15% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 1nf9 chain A Region: 7 - 169 Aligned: 161 Modelled: 163 Confidence: 100.0% Identity: 22% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3kl2 chain K Region: 7 - 173 Aligned: 167 Modelled: 167 Confidence: 100.0% Identity: 20% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis Phyre2 PDB 3mcw chain A Region: 7 - 174 Aligned: 166 Modelled: 168 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution Phyre2 PDB 3oqp chain A Region: 12 - 179 Aligned: 165 Modelled: 167 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3oqp chain B Region: 12 - 179 Aligned: 165 Modelled: 167 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3hu5 chain B Region: 11 - 174 Aligned: 161 Modelled: 162 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough Phyre2 PDB 3ot4 chain F Region: 10 - 171 Aligned: 159 Modelled: 162 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf Phyre2 PDB 3eef chain A Region: 12 - 169 Aligned: 154 Modelled: 158 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum Phyre2 PDB 3hb7 chain G Region: 11 - 173 Aligned: 160 Modelled: 161 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a Phyre2 PDB 1im5 chain A Region: 12 - 165 Aligned: 154 Modelled: 154 Confidence: 100.0% Identity: 21% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3r2j chain C Region: 6 - 171 Aligned: 164 Modelled: 166 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate Phyre2 PDB 3lqy chain A Region: 7 - 170 Aligned: 160 Modelled: 161 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica Phyre2 1 d1yaca_ 2 c2b34C_ 3 c1yzvA_ 4 d1x9ga_ 5 c2fq1A_ 6 c3irvA_ 7 d1j2ra_ 8 d1nbaa_ 9 d1nf9a_ 10 c3kl2K_ 11 c3mcwA_ 12 c3oqpA_ 13 c3oqpB_ 14 c3hu5B_ 15 c3ot4F_ 16 c3eefA_ 17 c3hb7G_ 18 d1im5a_ 19 c3r2jC_ 20 c3lqyA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1yaca_ 100.0 98 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 2 c2b34C_ 100.0 25 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 3 c1yzvA_ 100.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: hypothetical protein from trypanosoma cruzi 4 d1x9ga_ 100.0 17 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 5 c2fq1A_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains 6 c3irvA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a 7 d1j2ra_ 100.0 17 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 8 d1nbaa_ 100.0 15 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 9 d1nf9a_ 100.0 22 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 10 c3kl2K_ 100.0 20 PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis 11 c3mcwA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution 12 c3oqpA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 13 c3oqpB_ 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 14 c3hu5B_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough 15 c3ot4F_ 100.0 19 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 16 c3eefA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum 17 c3hb7G_ 100.0 18 PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a 18 d1im5a_ 100.0 21 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 19 c3r2jC_ 100.0 17 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate 20 c3lqyA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica 21 c3o93A_ not modelled 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes 22 c2wtaA_ not modelled 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease 23 c2a67C_ not modelled 100.0 21 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein 24 c3gbcA_ not modelled 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide 25 c2h0rD_ not modelled 100.0 22 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 26 d1cmwa2 not modelled 84.6 24 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 27 c3o26A_ not modelled 82.4 14 PDB header:oxidoreductase Chain: A: PDB Molecule:salutaridine reductase; PDBTitle: the structure of salutaridine reductase from papaver somniferum. 28 d2ae2a_ not modelled 81.3 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 29 d1vp8a_ not modelled 79.4 27 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 30 d1xdpa3 not modelled 75.8 21 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 31 d1a9xa3 not modelled 75.7 33 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 32 c3toxG_ not modelled 75.5 25 PDB header:oxidoreductase Chain: G: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021 33 d1ae1a_ not modelled 73.2 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 34 c3ldaA_ not modelled 73.0 18 PDB header:dna binding protein Chain: A: PDB Molecule:dna repair protein rad51; PDBTitle: yeast rad51 h352y filament interface mutant 35 d1gega_ not modelled 72.2 26 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 36 d1xg5a_ not modelled 71.3 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 37 d1xsea_ not modelled 67.2 22 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 38 d1xq1a_ not modelled 66.4 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 39 c3nugA_ not modelled 64.4 20 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase; PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti 40 c2c07A_ not modelled 63.7 13 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase; PDBTitle: oxoacyl-acp reductase of plasmodium falciparum 41 d2c07a1 not modelled 63.7 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 42 d1pv8a_ not modelled 62.6 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 43 c2nwqA_ not modelled 62.5 23 PDB header:oxidoreductase Chain: A: PDB Molecule:probable short-chain dehydrogenase; PDBTitle: short chain dehydrogenase from pseudomonas aeruginosa 44 c3sjuA_ not modelled 62.3 21 PDB header:oxidoreductase Chain: A: PDB Molecule:keto reductase; PDBTitle: hedamycin polyketide ketoreductase bound to nadph 45 c3ijrF_ not modelled 62.2 15 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family; PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+ 46 c2ihnA_ not modelled 61.9 10 PDB header:hydrolase/dna Chain: A: PDB Molecule:ribonuclease h; PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate 47 c2cfcB_ not modelled 61.3 17 PDB header:oxidoreductase Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase; PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases 48 d1tfra2 not modelled 61.0 10 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 49 c2pd6D_ not modelled 60.7 13 PDB header:oxidoreductase Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8; PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8 50 c2vyeA_ not modelled 60.6 15 PDB header:hydrolase Chain: A: PDB Molecule:replicative dna helicase; PDBTitle: crystal structure of the dnac-ssdna complex 51 c2qq5A_ not modelled 60.5 17 PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase/reductase sdr family member 1; PDBTitle: crystal structure of human sdr family member 1 52 d1xu9a_ not modelled 60.3 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 53 c3imfA_ not modelled 60.0 23 PDB header:oxidoreductase Chain: A: PDB Molecule:short chain dehydrogenase; PDBTitle: 1.99 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' 54 c3bh0A_ not modelled 58.9 12 PDB header:replication Chain: A: PDB Molecule:dnab-like replicative helicase; PDBTitle: atpase domain of g40p 55 d1wmaa1 not modelled 58.0 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 56 d1f2da_ not modelled 57.6 13 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 57 c1xdoB_ not modelled 56.1 23 PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase 58 d1xkqa_ not modelled 55.6 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 59 d1xhla_ not modelled 55.0 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 60 c3iccA_ not modelled 54.8 11 PDB header:oxidoreductase Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase; PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution 61 c1x1qA_ not modelled 54.4 21 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8 62 d1qwga_ not modelled 54.0 23 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 63 c2nm0B_ not modelled 53.2 13 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2) 64 c2b4qB_ not modelled 52.7 19 PDB header:oxidoreductase Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl- PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex 65 c3svtA_ not modelled 51.7 20 PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain type dehydrogenase/reductase; PDBTitle: structure of a short-chain type dehydrogenase/reductase from2 mycobacterium ulcerans 66 d1qsga_ not modelled 51.3 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 67 c3cxtA_ not modelled 50.9 13 PDB header:oxidoreductase Chain: A: PDB Molecule:dehydrogenase with different specificities; PDBTitle: quaternary complex structure of gluconate 5-dehydrogenase from2 streptococcus suis type 2 68 c2uvdE_ not modelled 50.0 19 PDB header:oxidoreductase Chain: E: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase; PDBTitle: the crystal structure of a 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis (ba3989) 69 d1tyza_ not modelled 49.9 13 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 70 c1f8sA_ not modelled 49.9 21 PDB header:oxidoreductase Chain: A: PDB Molecule:l-amino acid oxidase; PDBTitle: crystal structure of l-amino acid oxidase from calloselasma2 rhodostoma, complexed with three molecules of o-aminobenzoate. 71 c3rd5A_ not modelled 49.8 20 PDB header:oxidoreductase Chain: A: PDB Molecule:mypaa.01249.c; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium paratuberculosis 72 c3tfoD_ not modelled 49.1 15 PDB header:oxidoreductase Chain: D: PDB Molecule:putative 3-oxoacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl-carrier-protein)2 reductase from sinorhizobium meliloti 73 c3t4xA_ not modelled 49.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family; PDBTitle: short chain dehydrogenase/reductase family oxidoreductase from2 bacillus anthracis str. ames ancestor 74 c3ak4C_ not modelled 48.8 18 PDB header:oxidoreductase Chain: C: PDB Molecule:nadh-dependent quinuclidinone reductase; PDBTitle: crystal structure of nadh-dependent quinuclidinone reductase from2 agrobacterium tumefaciens 75 d2zdra2 not modelled 48.7 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 76 c3lylB_ not modelled 48.5 13 PDB header:oxidoreductase Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase; PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis 77 c3bgwD_ not modelled 48.3 12 PDB header:replication Chain: D: PDB Molecule:dnab-like replicative helicase; PDBTitle: the structure of a dnab-like replicative helicase and its interactions2 with primase 78 c3pk0B_ not modelled 47.5 19 PDB header:oxidoreductase Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: crystal structure of short-chain dehydrogenase/reductase sdr from2 mycobacterium smegmatis 79 d1w7ab4 not modelled 47.4 21 Fold:MutS N-terminal domain-like Superfamily:DNA repair protein MutS, domain I Family:DNA repair protein MutS, domain I 80 c3ai3A_ not modelled 46.9 20 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph-sorbose reductase; PDBTitle: the crystal structure of l-sorbose reductase from gluconobacter2 frateurii complexed with nadph and l-sorbose 81 d1ulsa_ not modelled 46.5 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 82 d1d7oa_ not modelled 46.4 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 83 c2zatC_ not modelled 46.2 18 PDB header:oxidoreductase Chain: C: PDB Molecule:dehydrogenase/reductase sdr family member 4; PDBTitle: crystal structure of a mammalian reductase 84 c1cmwA_ not modelled 46.0 25 PDB header:transferase Chain: A: PDB Molecule:protein (dna polymerase i); PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain 85 c3lf2B_ not modelled 44.5 15 PDB header:oxidoreductase Chain: B: PDB Molecule:short chain oxidoreductase q9hya2; PDBTitle: nadph bound structure of the short chain oxidoreductase q9hya2 from2 pseudomonas aeruginosa pao1 containing an atypical catalytic center 86 d1t57a_ not modelled 43.1 20 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 87 d1w6ua_ not modelled 42.8 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 88 d1y5ma1 not modelled 42.6 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 89 d1zema1 not modelled 41.8 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 90 c3gafF_ not modelled 41.5 19 PDB header:oxidoreductase Chain: F: PDB Molecule:7-alpha-hydroxysteroid dehydrogenase; PDBTitle: 2.2a crystal structure of 7-alpha-hydroxysteroid2 dehydrogenase from brucella melitensis 91 c2p68A_ not modelled 41.4 11 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5 92 c1yb1B_ not modelled 41.2 13 PDB header:oxidoreductase Chain: B: PDB Molecule:17-beta-hydroxysteroid dehydrogenase type xi; PDBTitle: crystal structure of human 17-beta-hydroxysteroid dehydrogenase type2 xi 93 c2jahB_ not modelled 40.9 25 PDB header:oxidoreductase Chain: B: PDB Molecule:clavulanic acid dehydrogenase; PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus 94 c3oidA_ not modelled 40.3 13 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph]; PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl) 95 d1pr9a_ not modelled 39.7 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 96 d1qopb_ not modelled 39.6 21 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 97 d1q7ba_ not modelled 39.6 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 98 d1ooea_ not modelled 39.4 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 99 c3o38D_ not modelled 39.3 24 PDB header:oxidoreductase Chain: D: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis 100 d1a9xa4 not modelled 38.9 21 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 101 d2rhca1 not modelled 38.7 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 102 d1edoa_ not modelled 38.4 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 103 c3r1iB_ not modelled 38.3 25 PDB header:oxidoreductase Chain: B: PDB Molecule:short-chain type dehydrogenase/reductase; PDBTitle: crystal structure of a short-chain type dehydrogenase/reductase from2 mycobacterium marinum 104 c2wdzD_ not modelled 38.3 12 PDB header:oxidoreductase Chain: D: PDB Molecule:short-chain dehydrogenase/reductase; PDBTitle: crystal structure of the short chain dehydrogenase2 galactitol-dehydrogenase (gatdh) of rhodobacter3 sphaeroides in complex with nad+ and 1,2-pentandiol 105 c3rkrC_ not modelled 37.8 15 PDB header:oxidoreductase Chain: C: PDB Molecule:short chain oxidoreductase; PDBTitle: crystal structure of a metagenomic short-chain oxidoreductase (sdr) in2 complex with nadp 106 d1x1ta1 not modelled 37.6 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 107 c3ctmH_ not modelled 37.4 17 PDB header:oxidoreductase Chain: H: PDB Molecule:carbonyl reductase; PDBTitle: crystal structure of a carbonyl reductase from candida2 parapsilosis with anti-prelog stereo-specificity 108 c2ztsB_ not modelled 37.3 20 PDB header:atp-binding protein Chain: B: PDB Molecule:putative uncharacterized protein ph0186; PDBTitle: crystal structure of kaic-like protein ph0186 from2 hyperthermophilic archaea pyrococcus horikoshii ot3 109 c3g8rA_ not modelled 37.2 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 110 d1vlia2 not modelled 37.0 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 111 d1yxma1 not modelled 37.0 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 112 c3m1aF_ not modelled 36.4 16 PDB header:oxidoreductase Chain: F: PDB Molecule:putative dehydrogenase; PDBTitle: the crystal structure of a short-chain dehydrogenase from2 streptomyces avermitilis to 2a 113 c3ioyB_ not modelled 36.4 14 PDB header:oxidoreductase Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr; PDBTitle: structure of putative short-chain dehydrogenase (saro_0793)2 from novosphingobium aromaticivorans 114 d1onfa2 not modelled 36.2 13 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 115 d1hdca_ not modelled 36.1 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 116 d1nffa_ not modelled 36.0 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 117 c2dy0A_ not modelled 35.9 30 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 118 c3kvoB_ not modelled 35.7 20 PDB header:oxidoreductase Chain: B: PDB Molecule:hydroxysteroid dehydrogenase-like protein 2; PDBTitle: crystal structure of the catalytic domain of human hydroxysteroid2 dehydrogenase like 2 (hsdl2) 119 c2ptgA_ not modelled 35.4 23 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: crystal structure of eimeria tenella enoyl reductase 120 d2a4ka1 not modelled 35.2 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0