Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A9H7
DateWed Jan 25 15:20:19 GMT 2012
Unique Job IDce980eaa9c0b0e6d

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1kpga_
Top template information
Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
Confidence and coverage
Confidence:100.0% Coverage: 70%
266 residues ( 70% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGE
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Disorder  ??





?
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   .........70.........80.........90.........100.........110.........120
Sequence  SYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHY
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??????










???????????







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   .........130.........140.........150.........160.........170.........180
Sequence  DLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGG
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   .........190.........200.........210.........220.........230.........240
Sequence  LAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEH
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   .........250.........260.........270.........280.........290.........300
Sequence  VGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQS
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????
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   .........310.........320.........330.........340.........350.........360
Sequence  SEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRA
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   .........370.........380..
Sequence  RDIQLWQVVFSRGVENGLRVAR
Secondary structure 













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Disorder 














???????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1kpg chain A

3D model

Region: 107 - 372
Aligned: 266
Modelled: 266
Confidence: 100.0%
Identity: 34%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Mycolic acid cyclopropane synthase

Phyre2

PDB 1kpi chain A

3D model

Region: 109 - 372
Aligned: 264
Modelled: 264
Confidence: 100.0%
Identity: 37%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Mycolic acid cyclopropane synthase

Phyre2

PDB 1tpy chain A

3D model

Region: 107 - 372
Aligned: 266
Modelled: 266
Confidence: 100.0%
Identity: 36%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Mycolic acid cyclopropane synthase

Phyre2

PDB 2fk8 chain A

3D model

Region: 116 - 377
Aligned: 262
Modelled: 262
Confidence: 100.0%
Identity: 31%
PDB header:transferase
Chain: A: PDB Molecule:methoxy mycolic acid synthase 4;
PDBTitle: crystal structure of hma (mmaa4) from mycobacterium tuberculosis2 complexed with s-adenosylmethionine

Phyre2

PDB 1l1e chain A

3D model

Region: 120 - 372
Aligned: 253
Modelled: 252
Confidence: 100.0%
Identity: 35%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Mycolic acid cyclopropane synthase

Phyre2

PDB 2fk8 chain A domain 1

3D model

Region: 117 - 377
Aligned: 261
Modelled: 261
Confidence: 100.0%
Identity: 31%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Mycolic acid cyclopropane synthase

Phyre2

PDB 2o57 chain A domain 1

3D model

Region: 113 - 373
Aligned: 258
Modelled: 261
Confidence: 100.0%
Identity: 18%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Mycolic acid cyclopropane synthase

Phyre2

PDB 3bus chain B

3D model

Region: 133 - 373
Aligned: 231
Modelled: 241
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of rebm

Phyre2

PDB 3ujc chain A

3D model

Region: 118 - 373
Aligned: 244
Modelled: 244
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:phosphoethanolamine n-methyltransferase;
PDBTitle: phosphoethanolamine methyltransferase mutant (h132a) from plasmodium2 falciparum in complex with phosphocholine

Phyre2

PDB 1nkv chain A

3D model

Region: 152 - 373
Aligned: 215
Modelled: 222
Confidence: 100.0%
Identity: 16%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Hypothetical Protein YjhP

Phyre2

PDB 3f4k chain A

3D model

Region: 132 - 373
Aligned: 233
Modelled: 242
Confidence: 100.0%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of a probable methyltransferase from2 bacteroides thetaiotaomicron. northeast structural3 genomics target btr309.

Phyre2

PDB 3e7p chain A

3D model

Region: 115 - 373
Aligned: 235
Modelled: 251
Confidence: 100.0%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of of putative methyltransferase from bacteroides2 vulgatus atcc 8482

Phyre2

PDB 3bkx chain B

3D model

Region: 130 - 351
Aligned: 218
Modelled: 220
Confidence: 99.9%
Identity: 17%
PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of cyclopropane-fatty-acyl-phospholipid synthase-2 like protein (yp_807781.1) from lactobacillus casei atcc 334 at 1.853 a resolution

Phyre2

PDB 2yr0 chain A

3D model

Region: 149 - 357
Aligned: 206
Modelled: 209
Confidence: 99.9%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha0223;
PDBTitle: crystal structure of hypothetical methyltransferase ttha0223 from2 thermus thermophilus hb8

Phyre2

PDB 3ocj chain A

3D model

Region: 114 - 320
Aligned: 207
Modelled: 206
Confidence: 99.9%
Identity: 18%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative exported protein;
PDBTitle: the crystal structure of a possilbe exported protein from bordetella2 parapertussis

Phyre2

PDB 3mq2 chain A

3D model

Region: 157 - 334
Aligned: 176
Modelled: 178
Confidence: 99.9%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:16s rrna methyltransferase;
PDBTitle: crystal structure of 16s rrna methyltranferase kamb

Phyre2

PDB 1vl5 chain A

3D model

Region: 156 - 337
Aligned: 177
Modelled: 182
Confidence: 99.9%
Identity: 20%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: UbiE/COQ5-like

Phyre2

PDB 1vl5 chain B

3D model

Region: 156 - 337
Aligned: 177
Modelled: 182
Confidence: 99.9%
Identity: 20%
PDB header:transferase
Chain: B: PDB Molecule:unknown conserved protein bh2331;
PDBTitle: crystal structure of a putative methyltransferase (bh2331) from2 bacillus halodurans c-125 at 1.95 a resolution

Phyre2

PDB 3bgv chain C

3D model

Region: 151 - 350
Aligned: 200
Modelled: 200
Confidence: 99.9%
Identity: 19%
PDB header:transferase
Chain: C: PDB Molecule:mrna cap guanine-n7 methyltransferase;
PDBTitle: crystal structure of mrna cap guanine-n7 methyltransferase2 in complex with sah

Phyre2

PDB 3mgg chain B

3D model

Region: 148 - 377
Aligned: 228
Modelled: 230
Confidence: 99.9%
Identity: 18%
PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of methyl transferase from methanosarcina2 mazei

Phyre2
1

d1kpga_
2

d1kpia_
3

d1tpya_
4

c2fk8A_
5

d1l1ea_
6

d2fk8a1
7

d2o57a1
8

c3busB_
9

c3ujcA_
10

d1nkva_
11

c3f4kA_
12

c3e7pA_
13

c3bkxB_
14

c2yr0A_
15

c3ocjA_
16

c3mq2A_
17

d1vl5a_
18

c1vl5B_
19

c3bgvC_
20

c3mggB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1kpga_



100.0 34 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
2d1kpia_



100.0 37 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
3d1tpya_



100.0 36 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
4c2fk8A_



100.0 31 PDB header:transferase
Chain: A: PDB Molecule:methoxy mycolic acid synthase 4;
PDBTitle: crystal structure of hma (mmaa4) from mycobacterium tuberculosis2 complexed with s-adenosylmethionine
5d1l1ea_



100.0 35 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
6d2fk8a1



100.0 31 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
7d2o57a1



100.0 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
8c3busB_



100.0 19 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of rebm
9c3ujcA_



100.0 18 PDB header:transferase
Chain: A: PDB Molecule:phosphoethanolamine n-methyltransferase;
PDBTitle: phosphoethanolamine methyltransferase mutant (h132a) from plasmodium2 falciparum in complex with phosphocholine
10d1nkva_



100.0 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical Protein YjhP
11c3f4kA_



100.0 15 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of a probable methyltransferase from2 bacteroides thetaiotaomicron. northeast structural3 genomics target btr309.
12c3e7pA_



100.0 16 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of of putative methyltransferase from bacteroides2 vulgatus atcc 8482
13c3bkxB_



99.9 17 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of cyclopropane-fatty-acyl-phospholipid synthase-2 like protein (yp_807781.1) from lactobacillus casei atcc 334 at 1.853 a resolution
14c2yr0A_



99.9 14 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha0223;
PDBTitle: crystal structure of hypothetical methyltransferase ttha0223 from2 thermus thermophilus hb8
15c3ocjA_



99.9 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative exported protein;
PDBTitle: the crystal structure of a possilbe exported protein from bordetella2 parapertussis
16c3mq2A_



99.9 14 PDB header:transferase
Chain: A: PDB Molecule:16s rrna methyltransferase;
PDBTitle: crystal structure of 16s rrna methyltranferase kamb
17d1vl5a_



99.9 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
18c1vl5B_



99.9 20 PDB header:transferase
Chain: B: PDB Molecule:unknown conserved protein bh2331;
PDBTitle: crystal structure of a putative methyltransferase (bh2331) from2 bacillus halodurans c-125 at 1.95 a resolution
19c3bgvC_



99.9 19 PDB header:transferase
Chain: C: PDB Molecule:mrna cap guanine-n7 methyltransferase;
PDBTitle: crystal structure of mrna cap guanine-n7 methyltransferase2 in complex with sah
20c3mggB_



99.9 18 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of methyl transferase from methanosarcina2 mazei
21d1xtpa_



not modelled 99.9 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:AD-003 protein-like
22d2ex4a1



not modelled 99.9 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:AD-003 protein-like
23d1xxla_



not modelled 99.9 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
24d1ri5a_



not modelled 99.9 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:mRNA cap (Guanine N-7) methyltransferase
25c1z3cA_



not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:mrna capping enzyme;
PDBTitle: encephalitozooan cuniculi mrna cap (guanine-n7)2 methyltransferasein complexed with azoadomet
26d1pjza_



not modelled 99.9 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Thiopurine S-methyltransferase
27d1wzna1



not modelled 99.9 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:CAC2371-like
28c3h2bB_



not modelled 99.9 15 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of the sam-dependent methyltransferase2 cg3271 from corynebacterium glutamicum in complex with s-3 adenosyl-l-homocysteine and pyrophosphate. northeast4 structural genomics consortium target cgr113a
29d1jqea_



not modelled 99.9 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Histamine methyltransferase
30c3lccA_



not modelled 99.9 20 PDB header:transferase
Chain: A: PDB Molecule:putative methyl chloride transferase;
PDBTitle: structure of a sam-dependent halide methyltransferase from arabidopsis2 thaliana
31c3e23A_



not modelled 99.9 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein rpa2492;
PDBTitle: crystal structure of the rpa2492 protein in complex with2 sam from rhodopseudomonas palustris, northeast structural3 genomics consortium target rpr299
32c3jwgA_



not modelled 99.9 14 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase type 12;
PDBTitle: crystal structure analysis of the methyltransferase domain2 of bacterial-cthen1-c
33d2bzga1



not modelled 99.9 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Thiopurine S-methyltransferase
34c3ccfB_



not modelled 99.9 20 PDB header:transferase
Chain: B: PDB Molecule:cyclopropane-fatty-acyl-phospholipid synthase;
PDBTitle: crystal structure of putative methyltransferase (yp_321342.1) from2 anabaena variabilis atcc 29413 at 1.90 a resolution
35c3m70A_



not modelled 99.9 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tellurite resistance protein tehb homolog;
PDBTitle: crystal structure of tehb from haemophilus influenzae
36c3g5lA_



not modelled 99.9 21 PDB header:transferase
Chain: A: PDB Molecule:putative s-adenosylmethionine dependent
PDBTitle: crystal structure of putative s-adenosylmethionine2 dependent methyltransferase from listeria monocytogenes
37c3bgdB_



not modelled 99.9 22 PDB header:transferase
Chain: B: PDB Molecule:thiopurine s-methyltransferase;
PDBTitle: thiopurine s-methyltransferase
38d1ve3a1



not modelled 99.9 27 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:CAC2371-like
39d1jg1a_



not modelled 99.8 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
40c3g5tA_



not modelled 99.8 23 PDB header:transferase
Chain: A: PDB Molecule:trans-aconitate 3-methyltransferase;
PDBTitle: crystal structure of trans-aconitate 3-methyltransferase2 from yeast
41c3dlcA_



not modelled 99.8 21 PDB header:transferase
Chain: A: PDB Molecule:putative s-adenosyl-l-methionine-dependent
PDBTitle: crystal structure of a putative s-adenosyl-l-methionine-dependent2 methyltransferase (mmp1179) from methanococcus maripaludis at 1.15 a3 resolution
42c3ou7A_



not modelled 99.8 15 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: dhpi-sam-hep complex
43d1r74a_



not modelled 99.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Glycine N-methyltransferase
44c3l8dA_



not modelled 99.8 23 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of methyltransferase from bacillus2 thuringiensis
45c2p8jA_



not modelled 99.8 21 PDB header:transferase
Chain: A: PDB Molecule:s-adenosylmethionine-dependent methyltransferase;
PDBTitle: crystal structure of s-adenosylmethionine-dependent methyltransferase2 (np_349143.1) from clostridium acetobutylicum at 2.00 a resolution
46c3ofkA_



not modelled 99.8 13 PDB header:transferase
Chain: A: PDB Molecule:nodulation protein s;
PDBTitle: crystal structure of n-methyltransferase nods from bradyrhizobium2 japonicum wm9 in complex with s-adenosyl-l-homocysteine (sah)
47d1xvaa_



not modelled 99.8 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Glycine N-methyltransferase
48c3cc8A_



not modelled 99.8 16 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of a putative methyltransferase (bce_1332) from2 bacillus cereus atcc 10987 at 1.64 a resolution
49d2a14a1



not modelled 99.8 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arylamine N-methyltransferase
50d2gh1a1



not modelled 99.8 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:BC2162-like
51c3lbfC_



not modelled 99.8 20 PDB header:transferase
Chain: C: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: crystal structure of protein l-isoaspartyl methyltransferase from2 escherichia coli
52c3ku1E_



not modelled 99.8 15 PDB header:transferase
Chain: E: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine
53c2gs9A_



not modelled 99.8 17 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein tt1324;
PDBTitle: crystal structure of tt1324 from thermus thermophilis hb8
54c3dliB_



not modelled 99.8 17 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of a sam dependent methyltransferase from2 archaeoglobus fulgidus
55c3ndjA_



not modelled 99.8 12 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: x-ray structure of a c-3'-methyltransferase in complex with s-2 adenosyl-l-homocysteine and sugar product
56d1dl5a1



not modelled 99.8 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
57c3hnrA_



not modelled 99.8 17 PDB header:transferase
Chain: A: PDB Molecule:probable methyltransferase bt9727_4108;
PDBTitle: crystal structure of a probable methyltransferase2 bt9727_4108 from bacillus thuringiensis subsp. northeast3 structural genomics consortium target id bur219
58d1zx0a1



not modelled 99.8 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
59c2p35A_



not modelled 99.8 13 PDB header:transferase
Chain: A: PDB Molecule:trans-aconitate 2-methyltransferase;
PDBTitle: crystal structure of trans-aconitate methyltransferase from2 agrobacterium tumefaciens
60c3ggdA_



not modelled 99.8 16 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of sam-dependent methyltransferase (yp_325210.1)2 from anabaena variabilis atcc 29413 at 2.11 a resolution
61d1im8a_



not modelled 99.8 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical protein HI0319 (YecO)
62c3g2qA_



not modelled 99.8 18 PDB header:transferase
Chain: A: PDB Molecule:pcza361.24;
PDBTitle: crystal structure of the glycopeptide n-methyltransferase mtfa2 complexed with sinefungin
63c2iipD_



not modelled 99.8 16 PDB header:transferase
Chain: D: PDB Molecule:nicotinamide n-methyltransferase;
PDBTitle: human nicotinamide n-methyltransferase
64d1xcla_



not modelled 99.8 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
65d1yzha1



not modelled 99.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TrmB-like
66c3lecA_



not modelled 99.8 15 PDB header:structure genomics, unknown function
Chain: A: PDB Molecule:nadb-rossmann superfamily protein;
PDBTitle: the crystal structure of a protein in the nadb-rossmann2 superfamily from streptococcus agalactiae to 1.8a
67c3egeA_



not modelled 99.8 20 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase from antibiotic biosynthesis
PDBTitle: crystal structure of putative methyltransferase from antibiotic2 biosynthesis pathway (yp_324569.1) from anabaena variabilis atcc3 29413 at 2.40 a resolution
68c3lstB_



not modelled 99.8 10 PDB header:transferase
Chain: B: PDB Molecule:calo1 methyltransferase;
PDBTitle: crystal structure of calo1, methyltransferase in calicheamicin2 biosynthesis, sah bound form
69c3gwzB_



not modelled 99.8 15 PDB header:transferase
Chain: B: PDB Molecule:mmcr;
PDBTitle: structure of the mitomycin 7-o-methyltransferase mmcr
70d1vbfa_



not modelled 99.8 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
71d1d2ha_



not modelled 99.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Glycine N-methyltransferase
72c3e05B_



not modelled 99.8 19 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y c5,15-methyltransferase (decarboxylating);
PDBTitle: crystal structure of precorrin-6y c5,15-methyltransferase from2 geobacter metallireducens gs-15
73d1m6ya2



not modelled 99.8 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:MraW-like putative methyltransferases
74c3p2kA_



not modelled 99.8 19 PDB header:transferase
Chain: A: PDB Molecule:16s rrna methylase;
PDBTitle: structure of an antibiotic related methyltransferase
75c3gnlB_



not modelled 99.8 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein, duf633, lmof2365_1472;
PDBTitle: structure of uncharacterized protein (lmof2365_1472) from2 listeria monocytogenes serotype 4b
76c3opnA_



not modelled 99.8 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative hemolysin;
PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis
77c3dh0B_



not modelled 99.8 19 PDB header:transferase
Chain: B: PDB Molecule:sam dependent methyltransferase;
PDBTitle: crystal structure of a sam dependent methyltransferase from2 aquifex aeolicus
78d2avna1



not modelled 99.8 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
79c2pxxA_



not modelled 99.8 25 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein mgc2408;
PDBTitle: human putative methyltransferase mgc2408
80d1qzza2



not modelled 99.8 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Plant O-methyltransferase, C-terminal domain
81c2yxeB_



not modelled 99.8 30 PDB header:transferase
Chain: B: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: crystal structure of l-isoaspartyl protein carboxyl methyltranferase
82c3bkwB_



not modelled 99.8 21 PDB header:transferase
Chain: B: PDB Molecule:s-adenosylmethionine dependent methyltransferase;
PDBTitle: crystal structure of s-adenosylmethionine dependent methyltransferase2 (np_104914.1) from mesorhizobium loti at 1.60 a resolution
83d1dusa_



not modelled 99.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical protein MJ0882
84d2fcaa1



not modelled 99.8 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TrmB-like
85c3e8sA_



not modelled 99.8 15 PDB header:transferase
Chain: A: PDB Molecule:putative sam dependent methyltransferase;
PDBTitle: crystal structure of putative sam dependent methyltransferase in2 complex with sah (np_744700.1) from pseudomonas putida kt2440 at 2.103 a resolution
86d1p1ca_



not modelled 99.8 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
87c3bxoA_



not modelled 99.8 14 PDB header:transferase
Chain: A: PDB Molecule:n,n-dimethyltransferase;
PDBTitle: crystal structure of streptomyces venezuelae desvi
88c3jwhA_



not modelled 99.8 20 PDB header:transferase
Chain: A: PDB Molecule:hen1;
PDBTitle: crystal structure analysis of the methyltransferase domain2 of bacterial-avhen1-c
89d1l3ia_



not modelled 99.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Precorrin-6Y methyltransferase (CbiT)
90c3dtnA_



not modelled 99.8 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative methyltransferase mm_2633;
PDBTitle: crystal structure of putative methyltransferase-mm_26332 from methanosarcina mazei .
91d1g8sa_



not modelled 99.8 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
92d1i1na_



not modelled 99.8 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
93c3grzA_



not modelled 99.8 20 PDB header:transferase
Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase;
PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus
94d1qama_



not modelled 99.8 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA adenine dimethylase-like
95c1x1aA_



not modelled 99.8 10 PDB header:transferase
Chain: A: PDB Molecule:crtf-related protein;
PDBTitle: crystal structure of bchu complexed with s-adenosyl-l-methionine
96c2pjdA_



not modelled 99.8 18 PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase c;
PDBTitle: crystal structure of 16s rrna methyltransferase rsmc
97c3mtiA_



not modelled 99.8 13 PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a
98d2p7ia1



not modelled 99.8 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
99d2nxca1



not modelled 99.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ribosomal protein L11 methyltransferase PrmA
100c3g07C_



not modelled 99.8 25 PDB header:transferase
Chain: C: PDB Molecule:7sk snrna methylphosphate capping enzyme;
PDBTitle: methyltransferase domain of human bicoid-interacting protein2 3 homolog (drosophila)
101c3pfhD_



not modelled 99.8 15 PDB header:transferase
Chain: D: PDB Molecule:n-methyltransferase;
PDBTitle: x-ray crystal structure the n,n-dimethyltransferase tylm1 from2 streptomyces fradiae in complex with sah and dtdp-quip3n
102d2i6ga1



not modelled 99.8 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TehB-like
103d1tw3a2



not modelled 99.8 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Plant O-methyltransferase, C-terminal domain
104c2p7iB_



not modelled 99.8 14 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of a sam dependent methyl-transferase type 12 family2 protein (eca1738) from pectobacterium atrosepticum scri1043 at 1.74 a3 resolution
105c3sm3A_



not modelled 99.8 22 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferases;
PDBTitle: crystal structure of sam-dependent methyltransferases q8puk2_metma2 from methanosarcina mazei. northeast structural genomics consortium3 target mar262.
106d1wg8a2



not modelled 99.7 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:MraW-like putative methyltransferases
107c1dl5A_



not modelled 99.7 27 PDB header:transferase
Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: protein-l-isoaspartate o-methyltransferase
108c3dp7B_



not modelled 99.7 15 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of sam-dependent methyltransferase from bacteroides2 vulgatus atcc 8482
109c1tw3A_



not modelled 99.7 17 PDB header:transferase
Chain: A: PDB Molecule:carminomycin 4-o-methyltransferase;
PDBTitle: crystal structure of carminomycin-4-o-methyltransferase2 (dnrk) in complex with s-adenosyl-l-homocystein (sah) and3 4-methoxy-e-rhodomycin t (m-et)
110c2r3sA_



not modelled 99.7 13 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a putative o-methyltransferase (npun_r0239) from2 nostoc punctiforme pcc 73102 at 2.15 a resolution
111c1yb2A_



not modelled 99.7 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ta0852;
PDBTitle: structure of a putative methyltransferase from thermoplasma2 acidophilum.
112d1yb2a1



not modelled 99.7 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
113c3mczB_



not modelled 99.7 13 PDB header:transferase
Chain: B: PDB Molecule:o-methyltransferase;
PDBTitle: the structure of an o-methyltransferase family protein from2 burkholderia thailandensis.
114c2ip2B_



not modelled 99.7 11 PDB header:transferase
Chain: B: PDB Molecule:probable phenazine-specific methyltransferase;
PDBTitle: structure of the pyocyanin biosynthetic protein phzm
115c2yvlB_



not modelled 99.7 24 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of trna (m1a58) methyltransferase trmi from aquifex2 aeolicus
116c3cggB_



not modelled 99.7 21 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of tehb-like sam-dependent methyltransferase2 (np_600671.1) from corynebacterium glutamicum atcc 13032 kitasato at3 2.00 a resolution
117c2pwyB_



not modelled 99.7 17 PDB header:transferase
Chain: B: PDB Molecule:trna (adenine-n(1)-)-methyltransferase;
PDBTitle: crystal structure of a m1a58 trna methyltransferase
118c3merA_



not modelled 99.7 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:slr1183 protein;
PDBTitle: crystal structure of the methyltransferase slr1183 from2 synechocystis sp. pcc 6803, northeast structural genomics3 consortium target sgr145
119c3dxyA_



not modelled 99.7 14 PDB header:transferase
Chain: A: PDB Molecule:trna (guanine-n(7)-)-methyltransferase;
PDBTitle: crystal structure of ectrmb in complex with sam
120c3i53A_



not modelled 99.7 11 PDB header:transferase
Chain: A: PDB Molecule:o-methyltransferase;
PDBTitle: crystal structure of an o-methyltransferase (ncsb1) from2 neocarzinostatin biosynthesis in complex with s-adenosyl-l-3 homocysteine (sah)

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0