Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	R	L	A	S	A	V	L	P	L	C	S	Q	H	P	G	Q	C	G	L	F	P	L	E	K	S	L	D	A	F	A	A	R	Y	R	L	A	E	M	A	E	H	T	L	D	V	Q	Y	Y	I	W	Q	D	D	M	S	G	R	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?		?		?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	F	S	A	L	L	A	A	A	K	R	G	V	R	V	R	L	L	L	D	D	N	N	T	P	G	L	D	D	I	L	R	L	L	D	S	H	P	R	I	E	V	R	L	F	N	P	F	S	F	R	L	L	R	P	L	G	Y	I	T
Secondary structure
SS confidence
Disorder																																																			?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	F	S	R	L	N	R	R	M	H	N	K	S	F	T	V	D	G	V	V	T	L	V	G	G	R	N	I	G	D	A	Y	F	G	A	G	E	E	P	L	F	S	D	L	D	V	M	A	I	G	P	V	V	E	D	V	A	D	D	F
Secondary structure
SS confidence
Disorder																																				?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	R	Y	W	Y	C	K	S	V	S	P	L	Q	Q	V	L	D	V	P	E	G	E	M	A	D	R	I	E	L	P	A	S	W	H	N	D	A	M	T	H	R	Y	L	R	K	M	E	S	S	P	F	I	N	H	L	V	D	G	T	L
Secondary structure
SS confidence
Disorder																								?									?	?	?	?	?	?	?	?	?	?							?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	L	I	W	A	K	T	R	L	L	S	D	D	P	A	K	G	E	G	K	A	K	R	H	S	L	L	P	Q	R	L	F	D	I	M	G	S	P	S	E	R	I	D	I	I	S	S	Y	F	V	P	T	R	A	G	V	A	Q	L	L
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	M	V	R	K	G	V	K	I	A	I	L	T	N	S	L	A	A	N	D	V	A	V	V	H	A	G	Y	A	R	W	R	K	K	L	L	R	Y	G	V	E	L	Y	E	L	K	P	T	R	E	Q	S	S	T	L	H	D	R	G	I
Secondary structure
SS confidence
Disorder																																																		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		T	G	N	S	G	A	S	L	H	A	K	T	F	S	I	D	G	K	T	V	F	I	G	S	F	N	F	D	P	R	S	T	L	L	N	T	E	M	G	F	V	I	E	S	E	T	L	A	Q	L	I	D	K	R	F	I	Q	S	Q	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.
Sequence		D	A	A	W	Q	L	R	L	D	R	W	G	R	I	N	W	V	D	R	H	A	K	K	E	I	I	L	K	K	E	P	A	T	S	F	W	K	R	V	M	V	R	L	A	S	I	L	P	V	E	W	L	L
Secondary structure
SS confidence
Disorder																							?																											?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1v0s chain A Region: 17 - 426 Aligned: 387 Modelled: 398 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:phospholipase d; PDBTitle: uninhibited form of phospholipase d from streptomyces sp.2 strain pmf Phyre2 PDB 3hsi chain C Region: 3 - 466 Aligned: 405 Modelled: 406 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: C: PDB Molecule:phosphatidylserine synthase; PDBTitle: crystal structure of phosphatidylserine synthase haemophilus2 influenzae rd kw20 Phyre2 PDB 1v0w chain A domain 1 Region: 15 - 221 Aligned: 196 Modelled: 197 Confidence: 100.0% Identity: 15% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Phospholipase D Phyre2 PDB 1xdo chain B Region: 22 - 433 Aligned: 288 Modelled: 286 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase Phyre2 PDB 1v0w chain A domain 2 Region: 15 - 193 Aligned: 171 Modelled: 178 Confidence: 99.9% Identity: 18% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Phospholipase D Phyre2 PDB 1xdp chain A domain 3 Region: 260 - 429 Aligned: 147 Modelled: 153 Confidence: 99.9% Identity: 20% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 1byr chain A Region: 263 - 425 Aligned: 140 Modelled: 146 Confidence: 99.9% Identity: 19% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Nuclease Phyre2 PDB 2o8r chain A Region: 22 - 433 Aligned: 297 Modelled: 309 Confidence: 99.8% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of polyphosphate kinase from2 porphyromonas gingivalis Phyre2 PDB 2o8r chain A domain 3 Region: 260 - 416 Aligned: 132 Modelled: 140 Confidence: 98.9% Identity: 16% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 1xdp chain A domain 4 Region: 265 - 433 Aligned: 134 Modelled: 135 Confidence: 98.6% Identity: 14% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 2o8r chain A domain 4 Region: 265 - 443 Aligned: 149 Modelled: 150 Confidence: 98.3% Identity: 17% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 2c1l chain A Region: 295 - 427 Aligned: 107 Modelled: 116 Confidence: 97.2% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease; PDBTitle: structure of the bfii restriction endonuclease Phyre2 PDB 1jy1 chain A domain 2 Region: 343 - 402 Aligned: 60 Modelled: 60 Confidence: 96.5% Identity: 23% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Tyrosyl-DNA phosphodiesterase TDP1 Phyre2 PDB 1nop chain B Region: 357 - 402 Aligned: 46 Modelled: 46 Confidence: 96.2% Identity: 28% PDB header:hydrolase/dna Chain: B: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure of human tyrosyl-dna phosphodiesterase2 (tdp1) in complex with vanadate, dna and a human3 topoisomerase i-derived peptide Phyre2 PDB 1q32 chain A domain 2 Region: 358 - 402 Aligned: 45 Modelled: 45 Confidence: 95.9% Identity: 20% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Tyrosyl-DNA phosphodiesterase TDP1 Phyre2 PDB 1q32 chain C Region: 362 - 402 Aligned: 41 Modelled: 41 Confidence: 95.7% Identity: 20% PDB header:replication,transcription,hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna2 phosphodiesterase Phyre2 PDB 3sq3 chain C Region: 357 - 402 Aligned: 46 Modelled: 46 Confidence: 95.0% Identity: 20% PDB header:hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna phosphodiesterase2 h182a mutant Phyre2 PDB 1qzq chain A domain 1 Region: 71 - 162 Aligned: 76 Modelled: 92 Confidence: 86.2% Identity: 13% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Tyrosyl-DNA phosphodiesterase TDP1 Phyre2 PDB 1jy1 chain A domain 1 Region: 71 - 161 Aligned: 75 Modelled: 91 Confidence: 85.3% Identity: 13% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Tyrosyl-DNA phosphodiesterase TDP1 Phyre2 PDB 1q32 chain A domain 1 Region: 366 - 404 Aligned: 38 Modelled: 39 Confidence: 68.2% Identity: 26% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Tyrosyl-DNA phosphodiesterase TDP1 Phyre2 1 c1v0sA_ 2 c3hsiC_ 3 d1v0wa1 4 c1xdoB_ 5 d1v0wa2 6 d1xdpa3 7 d1byra_ 8 c2o8rA_ 9 d2o8ra3 10 d1xdpa4 11 d2o8ra4 12 c2c1lA_ 13 d1jy1a2 14 c1nopB_ 15 d1q32a2 16 c1q32C_ 17 c3sq3C_ 18 d1qzqa1 19 d1jy1a1 20 d1q32a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1v0sA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:phospholipase d; PDBTitle: uninhibited form of phospholipase d from streptomyces sp.2 strain pmf 2 c3hsiC_ 100.0 18 PDB header:transferase Chain: C: PDB Molecule:phosphatidylserine synthase; PDBTitle: crystal structure of phosphatidylserine synthase haemophilus2 influenzae rd kw20 3 d1v0wa1 100.0 15 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Phospholipase D 4 c1xdoB_ 100.0 18 PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase 5 d1v0wa2 99.9 18 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Phospholipase D 6 d1xdpa3 99.9 20 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 7 d1byra_ 99.9 19 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Nuclease 8 c2o8rA_ 99.8 18 PDB header:transferase Chain: A: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of polyphosphate kinase from2 porphyromonas gingivalis 9 d2o8ra3 98.9 16 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 10 d1xdpa4 98.6 14 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 11 d2o8ra4 98.3 17 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 12 c2c1lA_ 97.2 22 PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease; PDBTitle: structure of the bfii restriction endonuclease 13 d1jy1a2 96.5 23 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 14 c1nopB_ 96.2 28 PDB header:hydrolase/dna Chain: B: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure of human tyrosyl-dna phosphodiesterase2 (tdp1) in complex with vanadate, dna and a human3 topoisomerase i-derived peptide 15 d1q32a2 95.9 20 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 16 c1q32C_ 95.7 20 PDB header:replication,transcription,hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna2 phosphodiesterase 17 c3sq3C_ 95.0 20 PDB header:hydrolase Chain: C: PDB Molecule:tyrosyl-dna phosphodiesterase 1; PDBTitle: crystal structure analysis of the yeast tyrosyl-dna phosphodiesterase2 h182a mutant 18 d1qzqa1 86.2 13 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 19 d1jy1a1 85.3 13 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 20 d1q32a1 68.2 26 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Tyrosyl-DNA phosphodiesterase TDP1 21 d1tfra2 not modelled 44.8 9 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 22 c2a5hC_ not modelled 39.2 17 PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). 23 d2f5tx2 not modelled 29.3 20 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:TrmB middle domain-like 24 d2pkqo1 not modelled 28.1 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 25 d1gz0a2 not modelled 26.6 22 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:RNA 2'-O ribose methyltransferase substrate binding domain 26 c3dy0B_ not modelled 26.2 33 PDB header:blood clotting, hydrolase inhibitor Chain: B: PDB Molecule:c-terminus plasma serine protease inhibitor; PDBTitle: crystal structure of cleaved pci bound to heparin 27 d1d7ya2 not modelled 25.8 13 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 28 d1gado1 not modelled 25.4 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 29 c1lq8H_ not modelled 24.7 33 PDB header:blood clotting Chain: H: PDB Molecule:plasma serine protease inhibitor; PDBTitle: crystal structure of cleaved protein c inhibitor 30 c3kgkA_ not modelled 24.5 13 PDB header:chaperone Chain: A: PDB Molecule:arsenical resistance operon trans-acting repressor arsd; PDBTitle: crystal structure of arsd 31 c2l82A_ not modelled 22.2 21 PDB header:de novo protein Chain: A: PDB Molecule:designed protein or32; PDBTitle: solution nmr structure of de novo designed protein, p-loop ntpase2 fold, northeast structural genomics consortium target or32 32 c3ecsD_ not modelled 21.8 15 PDB header:translation Chain: D: PDB Molecule:translation initiation factor eif-2b subunit PDBTitle: crystal structure of human eif2b alpha 33 d2bdea1 not modelled 21.0 41 Fold:HAD-like Superfamily:HAD-like Family:5' nucleotidase-like 34 d1gz0f2 not modelled 18.9 22 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:RNA 2'-O ribose methyltransferase substrate binding domain 35 c2f5tX_ not modelled 18.9 20 PDB header:transcription Chain: X: PDB Molecule:archaeal transcriptional regulator trmb; PDBTitle: crystal structure of the sugar binding domain of the archaeal2 transcriptional regulator trmb 36 d1u8fo1 not modelled 18.3 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 37 d2c4va1 not modelled 18.3 15 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 38 d1x94a_ not modelled 18.1 15 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 39 d1vc2a1 not modelled 16.9 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 40 c2krcA_ not modelled 16.8 26 PDB header:transcription Chain: A: PDB Molecule:dna-directed rna polymerase subunit delta; PDBTitle: solution structure of the n-terminal domain of bacillus2 subtilis delta subunit of rna polymerase 41 d1g5ha1 not modelled 16.3 8 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 42 d1j0xo1 not modelled 15.3 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 43 d2g82a1 not modelled 14.8 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 44 d2cula1 not modelled 14.7 21 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:GidA-like 45 c2jcmA_ not modelled 14.3 36 PDB header:hydrolase Chain: A: PDB Molecule:cytosolic purine 5'-nucleotidase; PDBTitle: crystal structure of human cytosolic 5'-nucleotidase ii in2 complex with beryllium trifluoride 46 c3gbcA_ not modelled 13.0 14 PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide 47 c3fxaA_ not modelled 12.9 20 PDB header:sugar binding protein Chain: A: PDB Molecule:sis domain protein; PDBTitle: crystal structure of a putative sugar-phosphate isomerase2 (lmof2365_0531) from listeria monocytogenes str. 4b f2365 at 1.60 a3 resolution 48 d1tk9a_ not modelled 12.8 10 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 49 c3a11D_ not modelled 12.7 13 PDB header:isomerase Chain: D: PDB Molecule:translation initiation factor eif-2b, delta PDBTitle: crystal structure of ribose-1,5-bisphosphate isomerase from2 thermococcus kodakaraensis kod1 50 d1v2da_ not modelled 12.7 14 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:AAT-like 51 c2xhzC_ not modelled 12.3 15 PDB header:isomerase Chain: C: PDB Molecule:arabinose 5-phosphate isomerase; PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography 52 d1jeoa_ not modelled 12.2 10 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 53 c2r60A_ not modelled 12.0 20 PDB header:transferase Chain: A: PDB Molecule:glycosyl transferase, group 1; PDBTitle: structure of apo sucrose phosphate synthase (sps) of2 halothermothrix orenii 54 c5acnA_ not modelled 11.8 13 PDB header:lyase(carbon-oxygen) Chain: A: PDB Molecule:aconitase; PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal 55 c2uygF_ not modelled 10.7 18 PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus 56 d1vb5a_ not modelled 10.7 15 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:IF2B-like 57 c3trjC_ not modelled 10.5 10 PDB header:isomerase Chain: C: PDB Molecule:phosphoheptose isomerase; PDBTitle: structure of a phosphoheptose isomerase from francisella tularensis 58 d1qd1a1 not modelled 10.5 13 Fold:Ferredoxin-like Superfamily:Formiminotransferase domain of formiminotransferase-cyclodeaminase. Family:Formiminotransferase domain of formiminotransferase-cyclodeaminase. 59 d1q1ra2 not modelled 10.4 8 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 60 d1j98a_ not modelled 10.4 24 Fold:LuxS/MPP-like metallohydrolase Superfamily:LuxS/MPP-like metallohydrolase Family:Autoinducer-2 production protein LuxS 61 c3hq4R_ not modelled 10.3 17 PDB header:oxidoreductase Chain: R: PDB Molecule:glyceraldehyde-3-phosphate dehydrogenase 1; PDBTitle: crystal structure of c151s mutant of glyceraldehyde-3-phosphate2 dehydrogenase 1 (gapdh1) complexed with nad from staphylococcus3 aureus mrsa252 at 2.2 angstrom resolution 62 d2qi2a3 not modelled 10.2 7 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:ERF1/Dom34 C-terminal domain-like 63 c2yvaB_ not modelled 10.1 18 PDB header:dna binding protein Chain: B: PDB Molecule:dnaa initiator-associating protein diaa; PDBTitle: crystal structure of escherichia coli diaa 64 c3shoA_ not modelled 10.0 22 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, rpir family; PDBTitle: crystal structure of rpir transcription factor from sphaerobacter2 thermophilus (sugar isomerase domain) 65 c1zhvA_ not modelled 9.9 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein atu0741; PDBTitle: x-ray crystal structure protein atu0741 from agobacterium tumefaciens.2 northeast structural genomics consortium target atr8. 66 d1o98a1 not modelled 9.5 20 Fold:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Superfamily:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 67 c2x3yA_ not modelled 9.3 15 PDB header:isomerase Chain: A: PDB Molecule:phosphoheptose isomerase; PDBTitle: crystal structure of gmha from burkholderia pseudomallei 68 d3gpdg1 not modelled 9.2 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 69 c2pr7A_ not modelled 8.7 23 PDB header:hydrolase Chain: A: PDB Molecule:haloacid dehalogenase/epoxide hydrolase family; PDBTitle: crystal structure of uncharacterized protein (np_599989.1) from2 corynebacterium glutamicum atcc 13032 kitasato at 1.44 a resolution 70 c3e9kA_ not modelled 8.6 2 PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex 71 d1obfo1 not modelled 8.5 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 72 c3hjaB_ not modelled 8.2 15 PDB header:oxidoreductase Chain: B: PDB Molecule:glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of glyceraldehyde-3-phosphate2 dehydrogenase from borrelia burgdorferi 73 d1pdoa_ not modelled 8.2 12 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:EIIA-man component-like 74 c2b34C_ not modelled 8.1 9 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 75 d1x92a_ not modelled 7.9 8 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 76 d1bxka_ not modelled 7.8 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 77 c2d1kC_ not modelled 7.7 36 PDB header:structural protein Chain: C: PDB Molecule:metastasis suppressor protein 1; PDBTitle: ternary complex of the wh2 domain of mim with actin-dnase i 78 c3l23A_ not modelled 7.5 6 PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of sugar phosphate isomerase/epimerase2 (yp_001303399.1) from parabacteroides distasonis atcc 8503 at 1.70 a3 resolution 79 d1rm4a1 not modelled 7.4 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 80 d1w6ka2 not modelled 7.3 20 Fold:alpha/alpha toroid Superfamily:Terpenoid cyclases/Protein prenyltransferases Family:Terpene synthases 81 c2y92A_ not modelled 7.2 17 PDB header:immune system Chain: A: PDB Molecule:toll/interleukin-1 receptor domain-containing adapter PDBTitle: crystal structure of mal adaptor protein 82 d3cmco1 not modelled 7.1 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 83 d1vima_ not modelled 7.1 15 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 84 d1kewa_ not modelled 7.0 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 85 d1wo8a1 not modelled 7.0 18 Fold:Methylglyoxal synthase-like Superfamily:Methylglyoxal synthase-like Family:Methylglyoxal synthase, MgsA 86 d1acoa2 not modelled 7.0 13 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 87 d2bisa1 not modelled 6.8 18 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Glycosyl transferases group 1 88 d2d59a1 not modelled 6.7 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 89 c3ff4A_ not modelled 6.6 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein chu_1412 90 c3ii7A_ not modelled 6.5 25 PDB header:protein binding Chain: A: PDB Molecule:kelch-like protein 7; PDBTitle: crystal structure of the kelch domain of human klhl7 91 d1nr3a_ not modelled 6.5 21 Fold:DNA-binding protein Tfx Superfamily:DNA-binding protein Tfx Family:DNA-binding protein Tfx 92 c3h75A_ not modelled 6.5 12 PDB header:sugar binding protein Chain: A: PDB Molecule:periplasmic sugar-binding domain protein; PDBTitle: crystal structure of a periplasmic sugar-binding protein from the2 pseudomonas fluorescens 93 d1rzua_ not modelled 6.4 20 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Glycosyl transferases group 1 94 c3l2iB_ not modelled 6.4 12 PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.85 angstrom crystal structure of the 3-dehydroquinate dehydratase2 (arod) from salmonella typhimurium lt2. 95 d3beda1 not modelled 6.3 15 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:EIIA-man component-like 96 d1nhpa2 not modelled 6.3 8 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 97 d1m3sa_ not modelled 6.2 18 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 98 d1h70a_ not modelled 6.1 14 Fold:Pentein, beta/alpha-propeller Superfamily:Pentein Family:Dimethylarginine dimethylaminohydrolase DDAH 99 d1ygha_ not modelled 6.0 9 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0