Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	Q	R	N	A	S	M	T	V	I	G	A	G	S	Y	G	T	A	L	A	I	T	L	A	R	N	G	H	E	V	V	L	W	G	H	D	P	E	H	I	A	T	L	E	R	D	R	C	N	A	A	F	L	P	D	V	P	F	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																																									?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	T	L	H	L	E	S	D	L	A	T	A	L	A	A	S	R	N	I	L	V	V	V	P	S	H	V	F	G	E	V	L	R	Q	I	K	P	L	M	R	P	D	A	R	L	V	W	A	T	K	G	L	E	A	E	T	G	R	L	L
Secondary structure
SS confidence
Disorder																																																				?	?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Q	D	V	A	R	E	A	L	G	D	Q	I	P	L	A	V	I	S	G	P	T	F	A	K	E	L	A	A	G	L	P	T	A	I	S	L	A	S	T	D	Q	T	F	A	D	D	L	Q	Q	L	L	H	C	G	K	S	F	R	V	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	N	P	D	F	I	G	V	Q	L	G	G	A	V	K	N	V	I	A	I	G	A	G	M	S	D	G	I	G	F	G	A	N	A	R	T	A	L	I	T	R	G	L	A	E	M	S	R	L	G	A	A	L	G	A	D	P	A	T	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		M	G	M	A	G	L	G	D	L	V	L	T	C	T	D	N	Q	S	R	N	R	R	F	G	M	M	L	G	Q	G	M	D	V	Q	S	A	Q	E	K	I	G	Q	V	V	E	G	Y	R	N	T	K	E	V	R	E	L	A	H	R	F
Secondary structure
SS confidence
Disorder																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.
Sequence		G	V	E	M	P	I	T	E	E	I	Y	Q	V	L	Y	C	G	K	N	A	R	E	A	A	L	T	L	L	G	R	A	R	K	D	E	R	S	S	H
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1m67 chain A Region: 6 - 336 Aligned: 327 Modelled: 331 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase; PDBTitle: crystal structure of leishmania mexicana gpdh complexed with inhibitor2 2-bromo-6-hydroxy-purine Phyre2 PDB 3k96 chain B Region: 5 - 330 Aligned: 323 Modelled: 326 Confidence: 100.0% Identity: 50% PDB header:oxidoreductase Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+]; PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii Phyre2 PDB 1wpq chain B Region: 5 - 331 Aligned: 322 Modelled: 327 Confidence: 100.0% Identity: 27% PDB header:oxidoreductase Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad+], PDBTitle: ternary complex of glycerol 3-phosphate dehydrogenase 12 with nad and dihydroxyactone Phyre2 PDB 1yj8 chain C Region: 1 - 333 Aligned: 328 Modelled: 333 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: C: PDB Molecule:glycerol-3-phosphate dehydrogenase; PDBTitle: initial structural analysis of plasmodium falciparum glycerol-3-2 phosphate dehydrogenase Phyre2 PDB 1z82 chain A Region: 6 - 327 Aligned: 309 Modelled: 314 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase; PDBTitle: crystal structure of glycerol-3-phosphate dehydrogenase (tm0378) from2 thermotoga maritima at 2.00 a resolution Phyre2 PDB 1txg chain A Region: 7 - 333 Aligned: 320 Modelled: 327 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+]; PDBTitle: structure of glycerol-3-phosphate dehydrogenase from archaeoglobus2 fulgidus Phyre2 PDB 1bg6 chain A Region: 5 - 338 Aligned: 309 Modelled: 324 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:n-(1-d-carboxylethyl)-l-norvaline dehydrogenase; PDBTitle: crystal structure of the n-(1-d-carboxylethyl)-l-norvaline2 dehydrogenase from arthrobacter sp. strain 1c Phyre2 PDB 2ew2 chain B Region: 7 - 329 Aligned: 298 Modelled: 317 Confidence: 100.0% Identity: 15% PDB header:oxidoreductase Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative; PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis Phyre2 PDB 3hn2 chain A Region: 7 - 316 Aligned: 293 Modelled: 310 Confidence: 100.0% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15 Phyre2 PDB 3hwr chain A Region: 7 - 314 Aligned: 284 Modelled: 290 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of pane/apba family ketopantoate reductase2 (yp_299159.1) from ralstonia eutropha jmp134 at 2.15 a resolution Phyre2 PDB 2qyt chain A Region: 4 - 314 Aligned: 273 Modelled: 273 Confidence: 100.0% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from porphyromonas2 gingivalis w83 Phyre2 PDB 2y0d chain B Region: 7 - 330 Aligned: 289 Modelled: 298 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: B: PDB Molecule:udp-glucose dehydrogenase; PDBTitle: bcec mutation y10k Phyre2 PDB 3ghy chain A Region: 6 - 314 Aligned: 285 Modelled: 309 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:ketopantoate reductase protein; PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2 Phyre2 PDB 1mv8 chain A Region: 7 - 333 Aligned: 287 Modelled: 294 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase; PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa Phyre2 PDB 2ofp chain B Region: 7 - 316 Aligned: 285 Modelled: 303 Confidence: 100.0% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:ketopantoate reductase; PDBTitle: crystal structure of escherichia coli ketopantoate2 reductase in a ternary complex with nadp+ and pantoate Phyre2 PDB 3gg2 chain B Region: 7 - 330 Aligned: 281 Modelled: 290 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate Phyre2 PDB 1ks9 chain A Region: 7 - 314 Aligned: 283 Modelled: 301 Confidence: 100.0% Identity: 14% PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: ketopantoate reductase from escherichia coli Phyre2 PDB 3g17 chain H Region: 7 - 314 Aligned: 274 Modelled: 308 Confidence: 100.0% Identity: 16% PDB header:structural genomics, unknown function Chain: H: PDB Molecule:similar to 2-dehydropantoate 2-reductase; PDBTitle: structure of putative 2-dehydropantoate 2-reductase from2 staphylococcus aureus Phyre2 PDB 1pgj chain A Region: 7 - 333 Aligned: 302 Modelled: 320 Confidence: 100.0% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase; PDBTitle: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan2 parasite t. brucei Phyre2 PDB 1pgq chain A Region: 5 - 331 Aligned: 295 Modelled: 327 Confidence: 100.0% Identity: 14% PDB header:oxidoreductase (choh(d)-nadp+(a)) Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase; PDBTitle: crystallographic study of coenzyme, coenzyme analogue and substrate2 binding in 6-phosphogluconate dehydrogenase: implications for nadp3 specificity and the enzyme mechanism Phyre2 1 c1m67A_ 2 c3k96B_ 3 c1wpqB_ 4 c1yj8C_ 5 c1z82A_ 6 c1txgA_ 7 c1bg6A_ 8 c2ew2B_ 9 c3hn2A_ 10 c3hwrA_ 11 c2qytA_ 12 c2y0dB_ 13 c3ghyA_ 14 c1mv8A_ 15 c2ofpB_ 16 c3gg2B_ 17 c1ks9A_ 18 c3g17H_ 19 c1pgjA_ 20 c1pgqA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499