Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	I	F	D	N	Y	E	V	W	F	V	I	G	S	Q	H	L	Y	G	P	E	T	L	R	Q	V	T	Q	H	A	E	H	V	V	N	A	L	N	T	E	A	K	L	P	C	K	L	V	L	K	P	L	G	T	T	P	D	E	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																					?													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	A	I	C	R	D	A	N	Y	D	D	R	C	A	G	L	V	V	W	L	H	T	F	S	P	A	K	M	W	I	N	G	L	T	M	L	N	K	P	L	L	Q	F	H	T	Q	F	N	A	A	L	P	W	D	S	I	D	M	D	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	N	L	N	Q	T	A	H	G	G	R	E	F	G	F	I	G	A	R	M	R	Q	Q	H	A	V	V	T	G	H	W	Q	D	K	Q	A	H	E	R	I	G	S	W	M	R	Q	A	V	S	K	Q	D	T	R	H	L	K	V	C	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	G	D	N	M	R	E	V	A	V	T	D	G	D	K	V	A	A	Q	I	K	F	G	F	S	V	N	T	W	A	V	G	D	L	V	Q	V	V	N	S	I	S	D	G	D	V	N	A	L	V	D	E	Y	E	S	C	Y	T	M	T
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	A	T	Q	I	H	G	K	K	R	Q	N	V	L	E	A	A	R	I	E	L	G	M	K	R	F	L	E	Q	G	G	F	H	A	F	T	T	T	F	E	D	L	H	G	L	K	Q	L	P	G	L	A	V	Q	R	L	M	Q	Q	G
Secondary structure
SS confidence
Disorder			?		?	?	?	?	?	?																																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Y	G	F	A	G	E	G	D	W	K	T	A	A	L	L	R	I	M	K	V	M	S	T	G	L	Q	G	G	T	S	F	M	E	D	Y	T	Y	H	F	E	K	G	N	D	L	V	L	G	S	H	M	L	E	V	C	P	S	I	A	A
Secondary structure
SS confidence
Disorder																							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		E	E	K	P	I	L	D	V	Q	H	L	G	I	G	G	K	D	D	P	A	R	L	I	F	N	T	Q	T	G	P	A	I	V	A	S	L	I	D	L	G	D	R	Y	R	L	L	V	N	C	I	D	T	V	K	T	P	H	S	L	P
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		K	L	P	V	A	N	A	L	W	K	A	Q	P	D	L	P	T	A	S	E	A	W	I	L	A	G	G	A	H	H	T	V	F	S	H	A	L	N	L	N	D	M	R	Q	F	A	E	M	H	D	I	E	I	T	V	I	D	N	D	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500
Sequence		R	L	P	A	F	K	D	A	L	R	W	N	E	V	Y	Y	G	F	R	R
Secondary structure
SS confidence
Disorder																?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2hxg chain B Region: 1 - 498 Aligned: 498 Modelled: 498 Confidence: 100.0% Identity: 99% PDB header:isomerase Chain: B: PDB Molecule:l-arabinose isomerase; PDBTitle: crystal structure of mn2+ bound ecai Phyre2 PDB 2ajt chain A domain 2 Region: 1 - 328 Aligned: 328 Modelled: 328 Confidence: 100.0% Identity: 99% Fold: FucI/AraA N-terminal and middle domains Superfamily: FucI/AraA N-terminal and middle domains Family: AraA N-terminal and middle domain-like Phyre2 PDB 2ajt chain A domain 1 Region: 329 - 498 Aligned: 170 Modelled: 170 Confidence: 100.0% Identity: 99% Fold: Reductase/isomerase/elongation factor common domain Superfamily: FucI/AraA C-terminal domain-like Family: AraA C-terminal domain-like Phyre2 PDB 1fui chain A domain 2 Region: 1 - 328 Aligned: 307 Modelled: 312 Confidence: 100.0% Identity: 12% Fold: FucI/AraA N-terminal and middle domains Superfamily: FucI/AraA N-terminal and middle domains Family: L-fucose isomerase, N-terminal and second domains Phyre2 PDB 1fui chain B Region: 1 - 481 Aligned: 453 Modelled: 453 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: B: PDB Molecule:l-fucose isomerase; PDBTitle: l-fucose isomerase from escherichia coli Phyre2 PDB 3a9r chain A Region: 11 - 481 Aligned: 444 Modelled: 453 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: A: PDB Molecule:d-arabinose isomerase; PDBTitle: x-ray structures of bacillus pallidus d-arabinose2 isomerasecomplex with (4r)-2-methylpentane-2,4-diol Phyre2 PDB 2c2x chain B Region: 14 - 80 Aligned: 67 Modelled: 67 Confidence: 87.2% Identity: 22% PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase- PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis Phyre2 PDB 1a4i chain A domain 2 Region: 15 - 80 Aligned: 66 Modelled: 66 Confidence: 86.5% Identity: 26% Fold: Aminoacid dehydrogenase-like, N-terminal domain Superfamily: Aminoacid dehydrogenase-like, N-terminal domain Family: Tetrahydrofolate dehydrogenase/cyclohydrolase Phyre2 PDB 1b0a chain A domain 2 Region: 15 - 80 Aligned: 66 Modelled: 66 Confidence: 84.7% Identity: 23% Fold: Aminoacid dehydrogenase-like, N-terminal domain Superfamily: Aminoacid dehydrogenase-like, N-terminal domain Family: Tetrahydrofolate dehydrogenase/cyclohydrolase Phyre2 PDB 3p2o chain A Region: 14 - 80 Aligned: 67 Modelled: 65 Confidence: 82.3% Identity: 22% PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni Phyre2 PDB 3ngl chain A Region: 16 - 80 Aligned: 65 Modelled: 65 Confidence: 81.6% Identity: 15% PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of bifunctional 5,10-methylenetetrahydrofolate2 dehydrogenase / cyclohydrolase from thermoplasma acidophilum Phyre2 PDB 3p2o chain B Region: 18 - 80 Aligned: 63 Modelled: 63 Confidence: 79.3% Identity: 21% PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni Phyre2 PDB 1a4i chain B Region: 15 - 80 Aligned: 66 Modelled: 66 Confidence: 77.9% Identity: 26% PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase / PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase Phyre2 PDB 1b0a chain A Region: 15 - 80 Aligned: 66 Modelled: 66 Confidence: 74.8% Identity: 23% PDB header:oxidoreductase,hydrolase Chain: A: PDB Molecule:protein (fold bifunctional protein); PDBTitle: 5,10, methylene-tetrahydropholate2 dehydrogenase/cyclohydrolase from e coli. Phyre2 PDB 1gca chain A Region: 30 - 169 Aligned: 139 Modelled: 140 Confidence: 74.7% Identity: 12% Fold: Periplasmic binding protein-like I Superfamily: Periplasmic binding protein-like I Family: L-arabinose binding protein-like Phyre2 PDB 1fui chain A domain 1 Region: 376 - 481 Aligned: 106 Modelled: 106 Confidence: 68.2% Identity: 15% Fold: Reductase/isomerase/elongation factor common domain Superfamily: FucI/AraA C-terminal domain-like Family: L-fucose isomerase, C-terminal domain Phyre2 PDB 4a5o chain B Region: 28 - 80 Aligned: 52 Modelled: 53 Confidence: 67.3% Identity: 19% PDB header:oxidoreductase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of pseudomonas aeruginosa n5, n10-2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold) Phyre2 PDB 3h5o chain B Region: 28 - 170 Aligned: 129 Modelled: 143 Confidence: 65.2% Identity: 10% PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator gntr; PDBTitle: the crystal structure of transcription regulator gntr from2 chromobacterium violaceum Phyre2 PDB 4a26 chain B Region: 40 - 80 Aligned: 41 Modelled: 41 Confidence: 64.3% Identity: 22% PDB header:oxidoreductase Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic; PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase Phyre2 PDB 2p2g chain D Region: 56 - 210 Aligned: 134 Modelled: 141 Confidence: 64.1% Identity: 16% PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form Phyre2 1 c2hxgB_ 2 d2ajta2 3 d2ajta1 4 d1fuia2 5 c1fuiB_ 6 c3a9rA_ 7 c2c2xB_ 8 d1a4ia2 9 d1b0aa2 10 c3p2oA_ 11 c3nglA_ 12 c3p2oB_ 13 c1a4iB_ 14 c1b0aA_ 15 d1gcaa_ 16 d1fuia1 17 c4a5oB_ 18 c3h5oB_ 19 c4a26B_ 20 c2p2gD_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2hxgB_ 100.0 99 PDB header:isomerase Chain: B: PDB Molecule:l-arabinose isomerase; PDBTitle: crystal structure of mn2+ bound ecai 2 d2ajta2 100.0 99 Fold:FucI/AraA N-terminal and middle domains Superfamily:FucI/AraA N-terminal and middle domains Family:AraA N-terminal and middle domain-like 3 d2ajta1 100.0 99 Fold:Reductase/isomerase/elongation factor common domain Superfamily:FucI/AraA C-terminal domain-like Family:AraA C-terminal domain-like 4 d1fuia2 100.0 12 Fold:FucI/AraA N-terminal and middle domains Superfamily:FucI/AraA N-terminal and middle domains Family:L-fucose isomerase, N-terminal and second domains 5 c1fuiB_ 100.0 14 PDB header:isomerase Chain: B: PDB Molecule:l-fucose isomerase; PDBTitle: l-fucose isomerase from escherichia coli 6 c3a9rA_ 100.0 14 PDB header:isomerase Chain: A: PDB Molecule:d-arabinose isomerase; PDBTitle: x-ray structures of bacillus pallidus d-arabinose2 isomerasecomplex with (4r)-2-methylpentane-2,4-diol 7 c2c2xB_ 87.2 22 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase- PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis 8 d1a4ia2 86.5 26 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 9 d1b0aa2 84.7 23 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 10 c3p2oA_ 82.3 22 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 11 c3nglA_ 81.6 15 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of bifunctional 5,10-methylenetetrahydrofolate2 dehydrogenase / cyclohydrolase from thermoplasma acidophilum 12 c3p2oB_ 79.3 21 PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 13 c1a4iB_ 77.9 26 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase / PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase 14 c1b0aA_ 74.8 23 PDB header:oxidoreductase,hydrolase Chain: A: PDB Molecule:protein (fold bifunctional protein); PDBTitle: 5,10, methylene-tetrahydropholate2 dehydrogenase/cyclohydrolase from e coli. 15 d1gcaa_ 74.7 12 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 16 d1fuia1 68.2 15 Fold:Reductase/isomerase/elongation factor common domain Superfamily:FucI/AraA C-terminal domain-like Family:L-fucose isomerase, C-terminal domain 17 c4a5oB_ 67.3 19 PDB header:oxidoreductase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of pseudomonas aeruginosa n5, n10-2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold) 18 c3h5oB_ 65.2 10 PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator gntr; PDBTitle: the crystal structure of transcription regulator gntr from2 chromobacterium violaceum 19 c4a26B_ 64.3 22 PDB header:oxidoreductase Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic; PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase 20 c2p2gD_ 64.1 16 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form 21 c3l07B_ not modelled 63.4 17 PDB header:oxidoreductase,hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis. 22 c2x7xA_ not modelled 61.2 10 PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: fructose binding periplasmic domain of hybrid two component2 system bt1754 23 c3bblA_ not modelled 60.5 12 PDB header:regulatory protein Chain: A: PDB Molecule:regulatory protein of laci family; PDBTitle: crystal structure of a regulatory protein of laci family from2 chloroflexus aggregans 24 c3oqbF_ not modelled 57.9 19 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110 25 c3v5nA_ not modelled 56.2 10 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: the crystal structure of oxidoreductase from sinorhizobium meliloti 26 c3nt5B_ not modelled 56.1 13 PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose 27 c3eafA_ not modelled 54.3 9 PDB header:transport protein Chain: A: PDB Molecule:abc transporter, substrate binding protein; PDBTitle: crystal structure of abc transporter, substrate binding protein2 aeropyrum pernix 28 d2dria_ not modelled 53.8 14 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 29 c3kkeA_ not modelled 51.4 12 PDB header:transcription regulator Chain: A: PDB Molecule:laci family transcriptional regulator; PDBTitle: crystal structure of a laci family transcriptional regulator2 from mycobacterium smegmatis 30 c3e18A_ not modelled 51.3 15 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of nad-binding protein from listeria innocua 31 c3ec7C_ not modelled 51.2 14 PDB header:oxidoreductase Chain: C: PDB Molecule:putative dehydrogenase; PDBTitle: crystal structure of putative dehydrogenase from salmonella2 typhimurium lt2 32 d1skyb3 not modelled 50.2 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 33 c3ksmA_ not modelled 47.1 11 PDB header:transport protein Chain: A: PDB Molecule:abc-type sugar transport system, periplasmic component; PDBTitle: crystal structure of abc-type sugar transport system, periplasmic2 component from hahella chejuensis 34 d2fvya1 not modelled 46.5 14 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 35 c3d8uA_ not modelled 45.6 11 PDB header:transcription regulator Chain: A: PDB Molecule:purr transcriptional regulator; PDBTitle: the crystal structure of a purr family transcriptional regulator from2 vibrio parahaemolyticus rimd 2210633 36 c3moiA_ not modelled 44.0 14 PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50 37 c2xecD_ not modelled 43.7 14 PDB header:isomerase Chain: D: PDB Molecule:putative maleate isomerase; PDBTitle: nocardia farcinica maleate cis-trans isomerase bound to2 tris 38 c3hcwB_ not modelled 43.0 8 PDB header:rna binding protein Chain: B: PDB Molecule:maltose operon transcriptional repressor; PDBTitle: crystal structure of probable maltose operon transcriptional repressor2 malr from staphylococcus areus 39 c3ctpB_ not modelled 41.9 11 PDB header:transcription regulator Chain: B: PDB Molecule:periplasmic binding protein/laci transcriptional regulator; PDBTitle: crystal structure of periplasmic binding protein/laci transcriptional2 regulator from alkaliphilus metalliredigens qymf complexed with d-3 xylulofuranose 40 c3gfgB_ not modelled 41.2 18 PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized oxidoreductase yvaa; PDBTitle: structure of putative oxidoreductase yvaa from bacillus subtilis in2 triclinic form 41 d8abpa_ not modelled 41.0 12 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 42 d1edza2 not modelled 40.6 27 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 43 d1hcza2 not modelled 40.3 28 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 44 c3l49D_ not modelled 39.5 9 PDB header:transport protein Chain: D: PDB Molecule:abc sugar (ribose) transporter, periplasmic PDBTitle: crystal structure of abc sugar transporter subunit from2 rhodobacter sphaeroides 2.4.1 45 d1dxha2 not modelled 39.2 14 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 46 c3kuxA_ not modelled 39.2 13 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis 47 c1h6dL_ not modelled 39.0 13 PDB header:protein translocation Chain: L: PDB Molecule:precursor form of glucose-fructose PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol 48 d2jdia3 not modelled 38.3 21 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 49 c3gr7A_ not modelled 38.2 17 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 50 d1gg2g_ not modelled 37.8 20 Fold:Non-globular all-alpha subunits of globular proteins Superfamily:Transducin (heterotrimeric G protein), gamma chain Family:Transducin (heterotrimeric G protein), gamma chain 51 c2r9vA_ not modelled 37.7 15 PDB header:hydrolase Chain: A: PDB Molecule:atp synthase subunit alpha; PDBTitle: crystal structure of atp synthase subunit alpha (tm1612) from2 thermotoga maritima at 2.10 a resolution 52 c3c1aB_ not modelled 37.1 17 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase (zp_00056571.1) from2 magnetospirillum magnetotacticum ms-1 at 1.85 a resolution 53 d2b7oa1 not modelled 37.0 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class-II DAHP synthetase 54 c3ceaA_ not modelled 35.0 10 PDB header:oxidoreductase Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase; PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution 55 d1omwg_ not modelled 34.9 20 Fold:Non-globular all-alpha subunits of globular proteins Superfamily:Transducin (heterotrimeric G protein), gamma chain Family:Transducin (heterotrimeric G protein), gamma chain 56 c2qu7B_ not modelled 34.4 5 PDB header:transcription Chain: B: PDB Molecule:putative transcriptional regulator; PDBTitle: crystal structure of a putative transcription regulator2 from staphylococcus saprophyticus subsp. saprophyticus 57 c3oa2B_ not modelled 34.3 17 PDB header:oxidoreductase Chain: B: PDB Molecule:wbpb; PDBTitle: crystal structure of the wlba (wbpb) dehydrogenase from pseudomonas2 aeruginosa in complex with nad at 1.5 angstrom resolution 58 c1ofgF_ not modelled 34.2 18 PDB header:oxidoreductase Chain: F: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: glucose-fructose oxidoreductase 59 d1lc0a1 not modelled 34.0 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 60 d1gqoa_ not modelled 33.7 15 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 61 d2nu7b1 not modelled 33.6 13 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 62 c3qk7C_ not modelled 32.9 15 PDB header:transcription regulator Chain: C: PDB Molecule:transcriptional regulators; PDBTitle: crystal structure of putative transcriptional regulator from yersinia2 pestis biovar microtus str. 91001 63 c1edzA_ not modelled 32.6 27 PDB header:oxidoreductase Chain: A: PDB Molecule:5,10-methylenetetrahydrofolate dehydrogenase; PDBTitle: structure of the nad-dependent 5,10-2 methylenetetrahydrofolate dehydrogenase from saccharomyces3 cerevisiae 64 d2gm3a1 not modelled 32.5 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 65 c1kxfA_ not modelled 32.2 26 PDB header:viral protein Chain: A: PDB Molecule:sindbis virus capsid protein; PDBTitle: sindbis virus capsid, (wild-type) residues 1-264,2 tetragonal crystal form (form ii) 66 d1auoa_ not modelled 32.1 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 67 c3fd8A_ not modelled 31.8 10 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis 68 c2rjoA_ not modelled 31.7 12 PDB header:signaling protein Chain: A: PDB Molecule:twin-arginine translocation pathway signal protein; PDBTitle: crystal structure of twin-arginine translocation pathway signal2 protein from burkholderia phytofirmans 69 d1ep5a_ not modelled 31.5 28 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Viral proteases 70 c3lkbB_ not modelled 31.4 10 PDB header:transport protein Chain: B: PDB Molecule:probable branched-chain amino acid abc PDBTitle: crystal structure of a branched chain amino acid abc2 transporter from thermus thermophilus with bound valine 71 c1zq1B_ not modelled 31.1 23 PDB header:lyase Chain: B: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: structure of gatde trna-dependent amidotransferase from2 pyrococcus abyssi 72 c3oa0B_ not modelled 30.8 20 PDB header:oxidoreductase Chain: B: PDB Molecule:lipopolysaccaride biosynthesis protein wbpb; PDBTitle: crystal structure of the wlba (wbpb) dehydrogenase from thermus2 thermophilus in complex with nad and udp-glcnaca 73 c3cn9B_ not modelled 30.7 12 PDB header:hydrolase Chain: B: PDB Molecule:carboxylesterase; PDBTitle: crystal structure analysis of the carboxylesterase pa3859 from2 pseudomonas aeruginosa pao1- orthorhombic crystal form 74 c1zh8B_ not modelled 30.7 12 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of oxidoreductase (tm0312) from thermotoga maritima2 at 2.50 a resolution 75 d1wyka_ not modelled 30.5 26 Fold:Trypsin-like serine proteases Superfamily:Trypsin-like serine proteases Family:Viral proteases 76 d1ci3m2 not modelled 30.5 21 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 77 c1tltB_ not modelled 29.3 17 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase (virulence factor mvim homolog); PDBTitle: crystal structure of a putative oxidoreductase (virulence factor mvim2 homolog) 78 c3f4lF_ not modelled 29.3 14 PDB header:oxidoreductase Chain: F: PDB Molecule:putative oxidoreductase yhhx; PDBTitle: crystal structure of a probable oxidoreductase yhhx in2 triclinic form. northeast structural genomics target er647 79 d1e2wa2 not modelled 29.2 32 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 80 d1fx0a3 not modelled 28.7 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 81 c2uygF_ not modelled 28.4 13 PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus 82 c3bdkB_ not modelled 28.2 11 PDB header:lyase Chain: B: PDB Molecule:d-mannonate dehydratase; PDBTitle: crystal structure of streptococcus suis mannonate2 dehydratase complexed with substrate analogue 83 c2glxD_ not modelled 28.0 14 PDB header:oxidoreductase Chain: D: PDB Molecule:1,5-anhydro-d-fructose reductase; PDBTitle: crystal structure analysis of bacterial 1,5-af reductase 84 d1gtza_ not modelled 27.7 19 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 85 d1ekxa2 not modelled 27.4 20 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 86 c3g85A_ not modelled 27.3 9 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator (laci family); PDBTitle: crystal structure of laci family transcription regulator from2 clostridium acetobutylicum 87 d1h6da1 not modelled 27.1 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 88 c3ezyB_ not modelled 27.0 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima 89 d1ydwa1 not modelled 26.8 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 90 c2pfsA_ not modelled 26.7 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:universal stress protein; PDBTitle: crystal structure of universal stress protein from nitrosomonas2 europaea 91 d2g50a2 not modelled 26.6 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 92 d1xima_ not modelled 26.3 13 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 93 c2vc6A_ not modelled 26.3 12 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound 94 c2p10D_ not modelled 26.0 14 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 95 c3sdoB_ not modelled 25.9 12 PDB header:oxidoreductase Chain: B: PDB Molecule:nitrilotriacetate monooxygenase; PDBTitle: structure of a nitrilotriacetate monooxygenase from burkholderia2 pseudomallei 96 d2c4va1 not modelled 25.2 19 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 97 d2h1ia1 not modelled 25.2 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 98 c1jyeA_ not modelled 25.0 15 PDB header:transcription Chain: A: PDB Molecule:lactose operon repressor; PDBTitle: structure of a dimeric lac repressor with c-terminal deletion and k84l2 substitution 99 d1jyea_ not modelled 25.0 15 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 100 c1xdwA_ not modelled 24.8 18 PDB header:oxidoreductase Chain: A: PDB Molecule:nad+-dependent (r)-2-hydroxyglutarate PDBTitle: nad+-dependent (r)-2-hydroxyglutarate dehydrogenase from2 acidaminococcus fermentans 101 c1lc3A_ not modelled 24.7 8 PDB header:oxidoreductase Chain: A: PDB Molecule:biliverdin reductase a; PDBTitle: crystal structure of a biliverdin reductase enzyme-cofactor2 complex 102 d1otha2 not modelled 24.7 18 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 103 d2glka1 not modelled 24.7 14 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 104 c3pf6C_ not modelled 24.5 39 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:hypothetical protein pp-luz7_gp033; PDBTitle: the structure of uncharacterized protein pp-luz7_gp033 from2 pseudomonas phage luz7. 105 c3gv0A_ not modelled 24.3 14 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, laci family; PDBTitle: crystal structure of laci family transcription regulator from2 agrobacterium tumefaciens 106 c3ip3D_ not modelled 24.3 14 PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase, putative; PDBTitle: structure of putative oxidoreductase (tm_0425) from2 thermotoga maritima 107 c1kmhA_ not modelled 24.1 16 PDB header:hydrolase Chain: A: PDB Molecule:atpase alpha subunit; PDBTitle: crystal structure of spinach chloroplast f1-atpase2 complexed with tentoxin 108 c2ixaA_ not modelled 23.9 15 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 109 c2zkqj_ not modelled 23.9 18 PDB header:ribosomal protein/rna Chain: J: PDB Molecule: PDBTitle: structure of a mammalian ribosomal 40s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map 110 c3db2C_ not modelled 23.8 13 PDB header:oxidoreductase Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase; PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution 111 d2a9da2 not modelled 23.7 20 Fold:Oxidoreductase molybdopterin-binding domain Superfamily:Oxidoreductase molybdopterin-binding domain Family:Oxidoreductase molybdopterin-binding domain 112 c2ehhE_ not modelled 23.3 13 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 113 d1y81a1 not modelled 23.0 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 114 d1uc2a_ not modelled 22.8 26 Fold:Hypothetical protein PH1602 Superfamily:Hypothetical protein PH1602 Family:Hypothetical protein PH1602 115 d1ryda1 not modelled 22.7 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 116 c2o48X_ not modelled 22.6 18 PDB header:oxidoreductase Chain: X: PDB Molecule:dimeric dihydrodiol dehydrogenase; PDBTitle: crystal structure of mammalian dimeric dihydrodiol dehydrogenase 117 c3bi8A_ not modelled 22.3 11 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum 118 c3eb2A_ not modelled 22.2 13 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 119 d1jx6a_ not modelled 22.2 10 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 120 c2qvcC_ not modelled 22.1 12 PDB header:transport protein Chain: C: PDB Molecule:sugar abc transporter, periplasmic sugar-binding PDBTitle: crystal structure of a periplasmic sugar abc transporter2 from thermotoga maritima

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0