Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP00562
DateThu Jan 5 10:56:45 GMT 2012
Unique Job IDb1d36fda3eb68ec7

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2cdqB_
Top template information
PDB header:transferase
Chain: B: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of arabidopsis thaliana aspartate kinase2 complexed with lysine and s-adenosylmethionine
Confidence and coverage
Confidence:100.0% Coverage: 55%
449 residues ( 55% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
799 residues ( 99%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGSTTNQLINW
Secondary structure 




























SS confidence 



























































Disorder  ??????????









































?






Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  LKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADSLISAFVSDLERLAALLDSGINDA
Secondary structure 










SS confidence 



























































Disorder 




?
??


















































Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  VYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAERAAQPQVDEGLSYPLLQQLL
Secondary structure 













SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  VQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
Secondary structure 




























SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSEIDLQLRCSYTPDQGSTRIER
Secondary structure 

























SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........310.........320.........330.........340.........350.........360
Sequence  VLASGTGARIVTSHDDVCLIEFQVPASQDFKLAHKEIDQILKRAQVRPLAVGVHNDRQLL
Secondary structure 

























SS confidence 



























































Disorder 
????

















?????























???




Disorder confidence 



























































 
   .........370.........380.........390.........400.........410.........420
Sequence  QFCYTSEVADSALKILDEAGLPGELRLRQGLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
Secondary structure 














SS confidence 



























































Disorder 





































?

?

















Disorder confidence 



























































 
   .........430.........440.........450.........460.........470.........480
Sequence  EFTWQSDDGISLVAVLRTGPTESLIQGLHQSVFRAEKRIGLVLFGKGNIGSRWLELFARE
Secondary structure 

















SS confidence 



























































Disorder 
































?
?
??




















Disorder confidence 



























































 
   .........490.........500.........510.........520.........530.........540
Sequence  QSTLSARTGFEFVLAGVVDSRRSLLSYDGLDASRALAFFNDEAVEQDEESLFLWMRAHPY
Secondary structure 


























SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........550.........560.........570.........580.........590.........600
Sequence  DDLVVLDVTASQQLADQYLDFASHGFHVISANKLAGASDSNKYRQIHDAFEKTGRHWLYN
Secondary structure 


















SS confidence 



























































Disorder 




































?





















Disorder confidence 



























































 
   .........610.........620.........630.........640.........650.........660
Sequence  ATVGAGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLT
Secondary structure 















SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........670.........680.........690.........700.........710.........720
Sequence  EPDPRDDLSGKDVMRKLVILAREAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNE
Secondary structure 
























SS confidence 



























































Disorder 






















???












?


??










??

Disorder confidence 



























































 
   .........730.........740.........750.........760.........770.........780
Sequence  QMVQRLEAAREMGLVLRYVARFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRD
Secondary structure 





















SS confidence 



























































Disorder 



































?






















Disorder confidence 



























































 
   .........790.........800.........810
Sequence  NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
Secondary structure 









SS confidence 





























Disorder 



























??
Disorder confidence 





























 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2cdq chain B

3D model

Region: 12 - 465
Aligned: 449
Modelled: 453
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: B: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of arabidopsis thaliana aspartate kinase2 complexed with lysine and s-adenosylmethionine

Phyre2

PDB 2j0w chain A

3D model

Region: 11 - 455
Aligned: 442
Modelled: 444
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:lysine-sensitive aspartokinase 3;
PDBTitle: crystal structure of e. coli aspartokinase iii in complex2 with aspartate and adp (r-state)

Phyre2

PDB 3c1n chain A

3D model

Region: 14 - 455
Aligned: 438
Modelled: 441
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:probable aspartokinase;
PDBTitle: crystal structure of allosteric inhibition threonine-sensitive2 aspartokinase from methanococcus jannaschii with l-threonine

Phyre2

PDB 3l76 chain B

3D model

Region: 11 - 501
Aligned: 425
Modelled: 433
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: B: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of aspartate kinase from synechocystis

Phyre2

PDB 3ab4 chain K

3D model

Region: 12 - 457
Aligned: 365
Modelled: 374
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: K: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of feedback inhibition resistant mutant of aspartate2 kinase from corynebacterium glutamicum in complex with lysine and3 threonine

Phyre2

PDB 3mtj chain A

3D model

Region: 453 - 809
Aligned: 316
Modelled: 327
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a

Phyre2

PDB 1ebu chain A

3D model

Region: 455 - 810
Aligned: 348
Modelled: 356
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: homoserine dehydrogenase complex with nad analogue and l-2 homoserine

Phyre2

PDB 3do5 chain A

3D model

Region: 458 - 809
Aligned: 319
Modelled: 331
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of putative homoserine dehydrogenase (np_069768.1)2 from archaeoglobus fulgidus at 2.20 a resolution

Phyre2

PDB 3c8m chain A

3D model

Region: 456 - 807
Aligned: 315
Modelled: 323
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of homoserine dehydrogenase from thermoplasma2 volcanium

Phyre2

PDB 3ing chain A

3D model

Region: 457 - 808
Aligned: 310
Modelled: 323
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of homoserine dehydrogenase (np_394635.1) from2 thermoplasma acidophilum at 1.95 a resolution

Phyre2

PDB 2ejw chain B

3D model

Region: 457 - 810
Aligned: 303
Modelled: 315
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: B: PDB Molecule:homoserine dehydrogenase;
PDBTitle: homoserine dehydrogenase from thermus thermophilus hb8

Phyre2

PDB 2cdq chain A domain 1

3D model

Region: 12 - 304
Aligned: 291
Modelled: 293
Confidence: 100.0%
Identity: 29%
Fold: Carbamate kinase-like
Superfamily: Carbamate kinase-like
Family: PyrH-like

Phyre2

PDB 2j0w chain A domain 1

3D model

Region: 11 - 303
Aligned: 290
Modelled: 293
Confidence: 100.0%
Identity: 29%
Fold: Carbamate kinase-like
Superfamily: Carbamate kinase-like
Family: PyrH-like

Phyre2

PDB 2hmf chain A domain 1

3D model

Region: 14 - 303
Aligned: 288
Modelled: 290
Confidence: 100.0%
Identity: 30%
Fold: Carbamate kinase-like
Superfamily: Carbamate kinase-like
Family: PyrH-like

Phyre2

PDB 1ebf chain A domain 2

3D model

Region: 608 - 791
Aligned: 183
Modelled: 184
Confidence: 100.0%
Identity: 42%
Fold: FwdE/GAPDH domain-like
Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family: Homoserine dehydrogenase-like

Phyre2

PDB 1ybd chain A domain 1

3D model

Region: 9 - 298
Aligned: 214
Modelled: 237
Confidence: 100.0%
Identity: 24%
Fold: Carbamate kinase-like
Superfamily: Carbamate kinase-like
Family: PyrH-like

Phyre2

PDB 2e9y chain A

3D model

Region: 11 - 300
Aligned: 269
Modelled: 275
Confidence: 100.0%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:carbamate kinase;
PDBTitle: crystal structure of project ape1968 from aeropyrum pernix k1

Phyre2

PDB 3k4y chain B

3D model

Region: 12 - 298
Aligned: 221
Modelled: 242
Confidence: 100.0%
Identity: 13%
PDB header:transferase
Chain: B: PDB Molecule:isopentenyl phosphate kinase;
PDBTitle: crystal structure of isopentenyl phosphate kinase from m. jannaschii2 in complex with ipp

Phyre2

PDB 3ek5 chain A

3D model

Region: 9 - 301
Aligned: 218
Modelled: 240
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:uridylate kinase;
PDBTitle: unique gtp-binding pocket and allostery of ump kinase from a gram-2 negative phytopathogen bacterium

Phyre2

PDB 3ll9 chain A

3D model

Region: 11 - 298
Aligned: 223
Modelled: 242
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:isopentenyl phosphate kinase;
PDBTitle: x-ray structures of isopentenyl phosphate kinase

Phyre2
1

c2cdqB_
2

c2j0wA_
3

c3c1nA_
4

c3l76B_
5

c3ab4K_
6

c3mtjA_
7

c1ebuA_
8

c3do5A_
9

c3c8mA_
10

c3ingA_
11

c2ejwB_
12

d2cdqa1
13

d2j0wa1
14

d2hmfa1
15

d1ebfa2
16

d1ybda1
17

c2e9yA_
18

c3k4yB_
19

c3ek5A_
20

c3ll9A_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139



140



141



142



143



144



145



146



147



148



149



150



151



152



153



154



155



156



157



158



159



160



161



162



163



164



165



166



167



168



169



170



171



172



173



174



175



176



177



178



179



180



181



182



183



184



185



186



187



188



189



190



191



192



193



194



195



196



197



198



199



200



201



202



203



204



205



206



207



208



209



210



211



212



213



214



215



216



217



218



219



220



221



222



223



224



225



226



227



228



229



230



231



232



233



234



235



236



237



238



239



240



241



242



243



244



245



246



247



248



249



250



251



252



253



254



255



256



257



258



259



260



261



262



263



264



265



266



267



268



269



270



271



272



273



274



275



276



277



278



279



280



281



282



283



284



285



286



287



288



289



290



291



292



293



294



295



296



297



298



299



300



301



302



303



304



305



306



307



308



309



310



311



312



313



314



315



316



317



318



319



320



321



322



323



324



325



326



327



328



329



330



331



332



333



334



335



336



337



338



339



340



341



342



343



344



345



346



347



348



349



350



351



352



353



354



355



356



357



358



359



360



361



362



363



364



365



366



367



368



369



370



371



372



373



374



375



376



377



378



379



380



381



382



383



384



385



386



387



388



389



390



391



392



393



394



395



396



397



398



399



400



401



402



403



404



405



406



407



408



409



410



411



412



413



414



415



416



417



418



419



420



421



422



423



424



425



426



427



428



429



430



431



432



433



434



435



436



437



438



439



440



441



442



443



444



445



446



447



448



449



450



451



452



453



454



455



456



457



458



459



460



461



462



463



464



465



466



467



468



469



470



471



472



473



474



475



476



477



478



479



480



481



482



483



484



485



486



487



488



489



490



491



492



493



494



495



496



497



498



499






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2cdqB_



100.0 24 PDB header:transferase
Chain: B: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of arabidopsis thaliana aspartate kinase2 complexed with lysine and s-adenosylmethionine
2c2j0wA_



100.0 24 PDB header:transferase
Chain: A: PDB Molecule:lysine-sensitive aspartokinase 3;
PDBTitle: crystal structure of e. coli aspartokinase iii in complex2 with aspartate and adp (r-state)
3c3c1nA_



100.0 24 PDB header:transferase
Chain: A: PDB Molecule:probable aspartokinase;
PDBTitle: crystal structure of allosteric inhibition threonine-sensitive2 aspartokinase from methanococcus jannaschii with l-threonine
4c3l76B_



100.0 24 PDB header:transferase
Chain: B: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of aspartate kinase from synechocystis
5c3ab4K_



100.0 26 PDB header:transferase
Chain: K: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of feedback inhibition resistant mutant of aspartate2 kinase from corynebacterium glutamicum in complex with lysine and3 threonine
6c3mtjA_



100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a
7c1ebuA_



100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: homoserine dehydrogenase complex with nad analogue and l-2 homoserine
8c3do5A_



100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of putative homoserine dehydrogenase (np_069768.1)2 from archaeoglobus fulgidus at 2.20 a resolution
9c3c8mA_



100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of homoserine dehydrogenase from thermoplasma2 volcanium
10c3ingA_



100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: crystal structure of homoserine dehydrogenase (np_394635.1) from2 thermoplasma acidophilum at 1.95 a resolution
11c2ejwB_



100.0 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:homoserine dehydrogenase;
PDBTitle: homoserine dehydrogenase from thermus thermophilus hb8
12d2cdqa1



100.0 29 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
13d2j0wa1



100.0 29 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
14d2hmfa1



100.0 30 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
15d1ebfa2



100.0 42 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:Homoserine dehydrogenase-like
16d1ybda1



100.0 24 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
17c2e9yA_



100.0 14 PDB header:transferase
Chain: A: PDB Molecule:carbamate kinase;
PDBTitle: crystal structure of project ape1968 from aeropyrum pernix k1
18c3k4yB_



100.0 13 PDB header:transferase
Chain: B: PDB Molecule:isopentenyl phosphate kinase;
PDBTitle: crystal structure of isopentenyl phosphate kinase from m. jannaschii2 in complex with ipp
19c3ek5A_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:uridylate kinase;
PDBTitle: unique gtp-binding pocket and allostery of ump kinase from a gram-2 negative phytopathogen bacterium
20c3ll9A_



100.0 23 PDB header:transferase
Chain: A: PDB Molecule:isopentenyl phosphate kinase;
PDBTitle: x-ray structures of isopentenyl phosphate kinase
21d2bnea1



not modelled 100.0 25 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
22d1e19a_



not modelled 100.0 12 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:Carbamate kinase
23d2a1fa1



not modelled 99.9 23 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
24c2rd5A_



not modelled 99.9 14 PDB header:protein binding
Chain: A: PDB Molecule:acetylglutamate kinase-like protein;
PDBTitle: structural basis for the regulation of n-acetylglutamate kinase by pii2 in arabidopsis thaliana
25d1gs5a_



not modelled 99.9 18 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:N-acetyl-l-glutamate kinase
26d2bufa1



not modelled 99.9 16 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:N-acetyl-l-glutamate kinase
27d1z9da1



not modelled 99.9 24 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
28c3nwyB_



not modelled 99.9 25 PDB header:transferase
Chain: B: PDB Molecule:uridylate kinase;
PDBTitle: structure and allosteric regulation of the uridine monophosphate2 kinase from mycobacterium tuberculosis
29c2dtjA_



not modelled 99.9 16 PDB header:transferase
Chain: A: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of regulatory subunit of aspartate kinase2 from corynebacterium glutamicum
30c2jjxC_



not modelled 99.9 19 PDB header:transferase
Chain: C: PDB Molecule:uridylate kinase;
PDBTitle: the crystal structure of ump kinase from bacillus anthracis2 (ba1797)
31c3ll5C_



not modelled 99.9 16 PDB header:transferase
Chain: C: PDB Molecule:gamma-glutamyl kinase related protein;
PDBTitle: crystal structure of t. acidophilum isopentenyl phosphate kinase2 product complex
32d1b7ba_



not modelled 99.9 11 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:Carbamate kinase
33d2brxa1



not modelled 99.9 25 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
34c3l86A_



not modelled 99.9 11 PDB header:transferase
Chain: A: PDB Molecule:acetylglutamate kinase;
PDBTitle: the crystal structure of smu.665 from streptococcus mutans ua159
35c2re1A_



not modelled 99.9 14 PDB header:transferase
Chain: A: PDB Molecule:aspartokinase, alpha and beta subunits;
PDBTitle: crystal structure of aspartokinase alpha and beta subunits
36c2va1A_



not modelled 99.9 19 PDB header:transferase
Chain: A: PDB Molecule:uridylate kinase;
PDBTitle: crystal structure of ump kinase from ureaplasma parvum
37d2ij9a1



not modelled 99.9 20 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
38c2egxA_



not modelled 99.9 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative acetylglutamate kinase;
PDBTitle: crystal structure of the putative acetylglutamate kinase from thermus2 thermophilus
39c2zhoB_



not modelled 99.9 18 PDB header:transferase
Chain: B: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of the regulatory subunit of aspartate2 kinase from thermus thermophilus (ligand free form)
40d2btya1



not modelled 99.9 18 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:N-acetyl-l-glutamate kinase
41d1ebfa1



not modelled 99.9 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
42d2akoa1



not modelled 99.9 19 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:PyrH-like
43c2v5hB_



not modelled 99.9 13 PDB header:transcription
Chain: B: PDB Molecule:acetylglutamate kinase;
PDBTitle: controlling the storage of nitrogen as arginine: the2 complex of pii and acetylglutamate kinase from3 synechococcus elongatus pcc 7942
44c3mahA_



not modelled 99.9 14 PDB header:transferase
Chain: A: PDB Molecule:aspartokinase;
PDBTitle: a putative c-terminal regulatory domain of aspartate kinase from2 porphyromonas gingivalis w83.
45c2w21A_



not modelled 99.9 17 PDB header:transferase
Chain: A: PDB Molecule:glutamate 5-kinase;
PDBTitle: crystal structure of the aminoacid kinase domain of the2 glutamate 5 kinase of escherichia coli.
46c2j4kC_



not modelled 99.9 21 PDB header:transferase
Chain: C: PDB Molecule:uridylate kinase;
PDBTitle: crystal structure of uridylate kinase from sulfolobus2 solfataricus in complex with ump to 2.2 angstrom3 resolution
47d2ap9a1



not modelled 99.8 16 Fold:Carbamate kinase-like
Superfamily:Carbamate kinase-like
Family:N-acetyl-l-glutamate kinase
48c3kzfC_



not modelled 99.8 15 PDB header:transferase
Chain: C: PDB Molecule:carbamate kinase;
PDBTitle: structure of giardia carbamate kinase
49c3d40A_



not modelled 99.8 22 PDB header:transferase
Chain: A: PDB Molecule:foma protein;
PDBTitle: crystal structure of fosfomycin resistance kinase foma from2 streptomyces wedmorensis complexed with diphosphate
50c2ogxB_



not modelled 99.8 22 PDB header:metal binding protein
Chain: B: PDB Molecule:molybdenum storage protein subunit beta;
PDBTitle: the crystal structure of the molybdenum storage protein from2 azotobacter vinelandii loaded with polyoxotungstates (wsto)
51c2j5tF_



not modelled 99.8 17 PDB header:transferase
Chain: F: PDB Molecule:glutamate 5-kinase;
PDBTitle: glutamate 5-kinase from escherichia coli complexed with2 glutamate
52c2ogxA_



not modelled 99.8 18 PDB header:metal binding protein
Chain: A: PDB Molecule:molybdenum storage protein subunit alpha;
PDBTitle: the crystal structure of the molybdenum storage protein from2 azotobacter vinelandii loaded with polyoxotungstates (wsto)
53c2f06B_



not modelled 99.7 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:conserved hypothetical protein;
PDBTitle: crystal structure of protein bt0572 from bacteroides thetaiotaomicron
54c2r98A_



not modelled 99.6 18 PDB header:transferase
Chain: A: PDB Molecule:putative acetylglutamate synthase;
PDBTitle: crystal structure of n-acetylglutamate synthase (selenomet2 substituted) from neisseria gonorrhoeae
55d2j0wa3



not modelled 99.5 20 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Aspartokinase allosteric domain-like
56d2hmfa2



not modelled 99.4 12 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Aspartokinase allosteric domain-like
57d2cdqa3



not modelled 99.4 20 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Aspartokinase allosteric domain-like
58d2hmfa3



not modelled 99.3 14 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Aspartokinase allosteric domain-like
59c2dc1A_



not modelled 99.3 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-aspartate dehydrogenase;
PDBTitle: crystal structure of l-aspartate dehydrogenase from2 hyperthermophilic archaeon archaeoglobus fulgidus
60c1r0lD_



not modelled 99.2 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate reductoisomerase from2 zymomonas mobilis in complex with nadph
61c2eghA_



not modelled 99.2 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase;
PDBTitle: crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase2 complexed with a magnesium ion, nadph and fosmidomycin
62c2jcyA_



not modelled 99.2 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase;
PDBTitle: x-ray structure of mutant 1-deoxy-d-xylulose 5-phosphate2 reductoisomerase, dxr, rv2870c, from mycobacterium3 tuberculosis
63d1j5pa4



not modelled 99.2 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
64c3a14B_



not modelled 99.2 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase;
PDBTitle: crystal structure of dxr from thermotoga maritima, in complex with2 nadph
65d1r0ka2



not modelled 99.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
66d1q0qa2



not modelled 99.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
67c3ceaA_



not modelled 98.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase;
PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution
68d2cdqa2



not modelled 98.9 7 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Aspartokinase allosteric domain-like
69c3e18A_



not modelled 98.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of nad-binding protein from listeria innocua
70c1zh8B_



not modelled 98.8 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of oxidoreductase (tm0312) from thermotoga maritima2 at 2.50 a resolution
71c3gfgB_



not modelled 98.8 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:uncharacterized oxidoreductase yvaa;
PDBTitle: structure of putative oxidoreductase yvaa from bacillus subtilis in2 triclinic form
72c1j5pA_



not modelled 98.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:aspartate dehydrogenase;
PDBTitle: crystal structure of aspartate dehydrogenase (tm1643) from thermotoga2 maritima at 1.9 a resolution
73c3evnA_



not modelled 98.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of putative oxidoreductase from streptococcus2 agalactiae 2603v/r
74c3e9mC_



not modelled 98.8 19 PDB header:oxidoreductase
Chain: C: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis
75c3ec7C_



not modelled 98.8 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dehydrogenase;
PDBTitle: crystal structure of putative dehydrogenase from salmonella2 typhimurium lt2
76c3euwB_



not modelled 98.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:myo-inositol dehydrogenase;
PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032
77c3kuxA_



not modelled 98.8 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis
78c2ho3D_



not modelled 98.7 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of oxidoreductase, gfo/idh/moca family from2 streptococcus pneumoniae
79c1h6dL_



not modelled 98.7 18 PDB header:protein translocation
Chain: L: PDB Molecule:precursor form of glucose-fructose
PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol
80c1ofgF_



not modelled 98.7 16 PDB header:oxidoreductase
Chain: F: PDB Molecule:glucose-fructose oxidoreductase;
PDBTitle: glucose-fructose oxidoreductase
81c1lc3A_



not modelled 98.7 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:biliverdin reductase a;
PDBTitle: crystal structure of a biliverdin reductase enzyme-cofactor2 complex
82c3db2C_



not modelled 98.7 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase;
PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution
83c2o48X_



not modelled 98.7 16 PDB header:oxidoreductase
Chain: X: PDB Molecule:dimeric dihydrodiol dehydrogenase;
PDBTitle: crystal structure of mammalian dimeric dihydrodiol dehydrogenase
84c3fd8A_



not modelled 98.7 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis
85c3v5nA_



not modelled 98.7 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase;
PDBTitle: the crystal structure of oxidoreductase from sinorhizobium meliloti
86c3fhlC_



not modelled 98.7 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from bacteroides2 fragilis nctc 9343
87d2j0wa2



not modelled 98.7 13 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Aspartokinase allosteric domain-like
88c3moiA_



not modelled 98.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable dehydrogenase;
PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50
89c3q2kB_



not modelled 98.7 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca
90c3rbvA_



not modelled 98.6 17 PDB header:sugar binding protein
Chain: A: PDB Molecule:sugar 3-ketoreductase;
PDBTitle: crystal structure of kijd10, a 3-ketoreductase from actinomadura2 kijaniata incomplex with nadp
91c3nt5B_



not modelled 98.6 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase;
PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose
92c3bioB_



not modelled 98.6 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of oxidoreductase (gfo/idh/moca family member) from2 porphyromonas gingivalis w83
93c3e82A_



not modelled 98.6 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from2 klebsiella pneumoniae
94d1ydwa1



not modelled 98.6 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
95c2q4eB_



not modelled 98.6 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:probable oxidoreductase at4g09670;
PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at4g09670
96c3ezyB_



not modelled 98.6 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima
97c2ixaA_



not modelled 98.6 16 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase;
PDBTitle: a-zyme, n-acetylgalactosaminidase
98c3f4lF_



not modelled 98.5 14 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative oxidoreductase yhhx;
PDBTitle: crystal structure of a probable oxidoreductase yhhx in2 triclinic form. northeast structural genomics target er647
99c3m2tA_



not modelled 98.5 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable dehydrogenase;
PDBTitle: the crystal structure of dehydrogenase from chromobacterium2 violaceum
100c3c1aB_



not modelled 98.5 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase (zp_00056571.1) from2 magnetospirillum magnetotacticum ms-1 at 1.85 a resolution
101c3dtyA_



not modelled 98.5 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of an oxidoreductase from pseudomonas2 syringae
102c2glxD_



not modelled 98.5 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:1,5-anhydro-d-fructose reductase;
PDBTitle: crystal structure analysis of bacterial 1,5-af reductase
103c2nvwB_



not modelled 98.5 13 PDB header:transcription
Chain: B: PDB Molecule:galactose/lactose metabolism regulatory protein
PDBTitle: crystal sctucture of transcriptional regulator gal80p from2 kluyveromymes lactis
104c2p2sA_



not modelled 98.5 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution
105d1zh8a1



not modelled 98.5 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
106c3oqbF_



not modelled 98.4 18 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110
107d1f06a1



not modelled 98.4 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
108c2axqA_



not modelled 98.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
109c3dapB_



not modelled 98.4 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:diaminopimelic acid dehydrogenase;
PDBTitle: c. glutamicum dap dehydrogenase in complex with nadp+ and2 the inhibitor 5s-isoxazoline
110c1evjC_



not modelled 98.3 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:glucose-fructose oxidoreductase;
PDBTitle: crystal structure of glucose-fructose oxidoreductase (gfor)2 delta1-22 s64d
111d1tlta1



not modelled 98.3 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
112c1e5lA_



not modelled 98.3 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine reductase;
PDBTitle: apo saccharopine reductase from magnaporthe grisea
113c1drwA_



not modelled 98.3 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrodipicolinate reductase;
PDBTitle: escherichia coli dhpr/nhdh complex
114c1xeaD_



not modelled 98.2 15 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family;
PDBTitle: crystal structure of a gfo/idh/moca family oxidoreductase2 from vibrio cholerae
115d2nvwa1



not modelled 98.2 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
116c3oa0B_



not modelled 98.2 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:lipopolysaccaride biosynthesis protein wbpb;
PDBTitle: crystal structure of the wlba (wbpb) dehydrogenase from thermus2 thermophilus in complex with nad and udp-glcnaca
117d1lc0a1



not modelled 98.2 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
118d1ryda1



not modelled 98.2 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
119c3ip3D_



not modelled 98.2 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:oxidoreductase, putative;
PDBTitle: structure of putative oxidoreductase (tm_0425) from2 thermotoga maritima
120c3uuwB_



not modelled 98.1 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase with nad(p)-binding rossmann-fold
PDBTitle: 1.63 angstrom resolution crystal structure of dehydrogenase (mvim)2 from clostridium difficile.

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0