Phyre 2 Results for P13656

Email	l.a.kelley@imperial.ac.uk
Description	P13656
Date	Thu Jan 5 11:33:39 GMT 2012
Unique Job ID	ada954da858f1b14

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2dskA_

Top template information

PDB header:hydrolase
Chain: A: PDB Molecule:chitinase;
PDBTitle: crystal structure of catalytic domain of hyperthermophilic chitinase2 from pyrococcus furiosus

Confidence and coverage

Confidence:

100.0%

Coverage:

33%

294 residues ( 33% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

426 residues ( 47%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M K L N I F T K S M I G M G L V C S A L P A L A M E A W N N Q Q G G N K Y Q V I F D G K I Y E N A W W V S S T N C P G K

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
?
? ? ? ? ?
?
?
? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence A K A N D A T N P W R L K R T A T A A E I S Q F G N T L S C E K S G S S S S S N S N T P A S N T P A N G G S A T P A Q G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ?
?
?
? ?
? ?
? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence T V P S N S S V V A W N K Q Q G G Q T W Y V V F N G A V Y K N A W W V A S S N C P G D A K S N D A S N P W R Y V R A A T

Secondary structure

SS confidence

Disorder ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence A T E I S E T S N P Q S C T S A P Q P S P D V K P A P D V K P A P D V Q P A P A D K S N D N Y A V V A W K G Q E G S S T

Secondary structure

SS confidence

Disorder ? ?
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ?
? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence W Y V I Y N G G I Y K N A W W V G A A N C P G D A K E N D A S N P W R Y V R A A T A T E I S Q Y G N P G S C S V K P D N

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence N G G A V T P V D P T P E T P V T P T P D N S E P S T P A D S V N D Y S L Q A W S G Q E G S E I Y H V I F N G N V Y K N

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ?
? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence A W W V G S K D C P R G T S A E N S N N P W R L E R T A T A A E L S Q Y G N P T T C E I D N G G V I V A D G F Q A S K A

Secondary structure

SS confidence

Disorder
? ?
? ? ?
? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence Y S A D S I V D Y N D A H Y K T S V D Q D A W G F V P G G D N P W K K Y E P A K A W S A S T V Y V K G D R V V V D G Q A

Secondary structure

SS confidence

Disorder
?
? ?
? ?
?
?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence Y E A L F W T Q S D N P A L V A N Q N A T G S N S R P W K P L G K A Q S Y S N E E L N N A P Q F N P E T L Y A S D T L I

Secondary structure

SS confidence

Disorder
?
?
? ? ?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence R F N G V N Y I S Q S K V Q K V S P S D S N P W R V F V D W T G T K E R V G T P K K A W P K H V Y A P Y V D F T L N T I

Secondary structure

SS confidence

Disorder ?
?
? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence P D L A A L A K N H N V N H F T L A F V V S K D A N T C L P T W G T A Y G M Q N Y A Q Y S K I K A L R E A G G D V M L S

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence I G G A N N A P L A A S C K N V D D L M Q H Y Y D I V D N L N L K V L D F D I E G T W V A D Q A S I E R R N L A V K K V

Secondary structure

SS confidence

Disorder
?
?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence Q D K W K S E G K D I A I W Y T L P I L P T G L T P E G M N V L S D A K A K G V E L A G V N V M T M D Y G N A I C Q S A

Secondary structure

SS confidence

Disorder
?
? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence N T E G Q N I H G K C A T S A I A N L H S Q L K G L H P N K S D A E I D A M M G T T P M V G V N D V Q G E V F Y L S D A

Secondary structure

SS confidence

Disorder ? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . .

Sequence R L V M Q D A Q K R N L G M V G I W S I A R D L P G G T N L S P E F H G L T K E Q A P K Y A F S E I F A P F T K Q

Secondary structure

SS confidence

Disorder
?
? ?
? ? ? ? ? ?
? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2dsk chain A

Region: 578 - 897
Aligned: 294
Modelled: 320
Confidence: 100.0%
Identity: 34%
PDB header:hydrolase
Chain: A: PDB Molecule:chitinase;
PDBTitle: crystal structure of catalytic domain of hyperthermophilic chitinase2 from pyrococcus furiosus

Phyre2

PDB 3ian chain A

Region: 586 - 897
Aligned: 295
Modelled: 312
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:chitinase;
PDBTitle: crystal structure of a chitinase from lactococcus lactis2 subsp. lactis

Phyre2

PDB 3ebv chain A

Region: 586 - 894
Aligned: 280
Modelled: 292
Confidence: 99.9%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:chinitase a;
PDBTitle: crystal structure of putative chitinase a from streptomyces2 coelicolor.

Phyre2

PDB 2hvm chain A

Region: 600 - 867
Aligned: 235
Modelled: 268
Confidence: 99.9%
Identity: 19%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: Type II chitinase

Phyre2

PDB 3d5h chain A

Region: 600 - 863
Aligned: 230
Modelled: 264
Confidence: 99.9%
Identity: 14%
PDB header:protein binding
Chain: A: PDB Molecule:haementhin;
PDBTitle: crystal structure of haementhin from haemanthus multiflorus2 at 2.0a resolution: formation of a novel loop on a tim3 barrel fold and its functional significance

Phyre2

PDB 2uy2 chain A

Region: 598 - 863
Aligned: 234
Modelled: 249
Confidence: 99.8%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:endochitinase;
PDBTitle: sccts1_apo crystal structure

Phyre2

PDB 3n12 chain A

Region: 584 - 894
Aligned: 283
Modelled: 294
Confidence: 99.8%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:chitinase a;
PDBTitle: crystal stricture of chitinase in complex with zinc atoms from2 bacillus cereus nctu2

Phyre2

PDB 2gsj chain A

Region: 602 - 863
Aligned: 228
Modelled: 251
Confidence: 99.8%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:protein ppl-2;
PDBTitle: cdna cloning and 1.75a crystal structure determination of2 ppl2, a novel chimerolectin from parkia platycephala seeds3 exhibiting endochitinolytic activity

Phyre2

PDB 1cnv chain A

Region: 593 - 863
Aligned: 244
Modelled: 260
Confidence: 99.8%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: Type II chitinase

Phyre2

PDB 3b9e chain A

Region: 504 - 865
Aligned: 355
Modelled: 362
Confidence: 99.7%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:chitinase a;
PDBTitle: crystal structure of inactive mutant e315m chitinase a from2 vibrio harveyi

Phyre2

PDB 2xuc chain A

Region: 602 - 863
Aligned: 238
Modelled: 251
Confidence: 99.7%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:chitinase;
PDBTitle: natural product-guided discovery of a fungal chitinase2 inhibitor

Phyre2

PDB 1itx chain A domain 1

Region: 578 - 866
Aligned: 271
Modelled: 289
Confidence: 99.7%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: Type II chitinase

Phyre2

PDB 1ur8 chain B

Region: 608 - 863
Aligned: 237
Modelled: 256
Confidence: 99.7%
Identity: 20%
PDB header:hydrolase
Chain: B: PDB Molecule:chitinase b;
PDBTitle: interactions of a family 18 chitinase with the designed2 inhibitor hm508, and its degradation product,3 chitobiono-delta-lactone

Phyre2

PDB 1rd6 chain A

Region: 504 - 865
Aligned: 355
Modelled: 355
Confidence: 99.7%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:chitinase a;
PDBTitle: crystal structure of s. marcescens chitinase a mutant w167a

Phyre2

PDB 1edq chain A domain 2

Region: 569 - 863
Aligned: 266
Modelled: 284
Confidence: 99.6%
Identity: 14%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: Type II chitinase

Phyre2

PDB 3co4 chain A

Region: 585 - 867
Aligned: 259
Modelled: 283
Confidence: 99.6%
Identity: 11%
PDB header:hydrolase
Chain: A: PDB Molecule:chitinase;
PDBTitle: crystal structure of a chitinase from bacteroides2 thetaiotaomicron

Phyre2

PDB 1jnd chain A domain 1

Region: 613 - 872
Aligned: 229
Modelled: 243
Confidence: 99.6%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: Type II chitinase

Phyre2

PDB 1w9p chain A domain 1

Region: 583 - 867
Aligned: 257
Modelled: 285
Confidence: 99.6%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: Type II chitinase

Phyre2

PDB 1ta3 chain A

Region: 602 - 863
Aligned: 227
Modelled: 244
Confidence: 99.6%
Identity: 19%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: Type II chitinase

Phyre2

PDB 3poh chain A

Region: 578 - 789
Aligned: 197
Modelled: 212
Confidence: 99.5%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:endo-beta-n-acetylglucosaminidase f1;
PDBTitle: crystal structure of an endo-beta-n-acetylglucosaminidase (bt_3987)2 from bacteroides thetaiotaomicron vpi-5482 at 1.55 a resolution

Phyre2

PDB 2d49 chain A

Region: 459 - 518
Aligned: 50
Modelled: 50
Confidence: 99.2%
Identity: 40%
PDB header:hydrolase
Chain: A: PDB Molecule:chitinase c;
PDBTitle: solution structure of the chitin-binding domain of2 streptomyces griseus chitinase c

Phyre2

PDB 1wgo chain A

Region: 287 - 369
Aligned: 83
Modelled: 83
Confidence: 72.2%
Identity: 12%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: PKD domain
Family: PKD domain

Phyre2

PDB 2c26 chain A

Region: 298 - 369
Aligned: 72
Modelled: 72
Confidence: 68.1%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase;
PDBTitle: structural basis for the promiscuous specificity of the2 carbohydrate-binding modules from the beta-sandwich super3 family

Phyre2

100

101

102

103

104

105

106

107

108

109

110

111

112

113

114

115

116

117

118

119

120

121

122

123

124

125

126

127

128

129

130

131

132

Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	K	L	N	I	F	T	K	S	M	I	G	M	G	L	V	C	S	A	L	P	A	L	A	M	E	A	W	N	N	Q	Q	G	G	N	K	Y	Q	V	I	F	D	G	K	I	Y	E	N	A	W	W	V	S	S	T	N	C	P	G	K
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?																		?			?	?	?	?	?																				?		?		?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	A	K	A	N	D	A	T	N	P	W	R	L	K	R	T	A	T	A	A	E	I	S	Q	F	G	N	T	L	S	C	E	K	S	G	S	S	S	S	S	N	S	N	T	P	A	S	N	T	P	A	N	G	G	S	A	T	P	A	Q	G
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?		?		?					?	?		?	?		?	?	?				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	T	V	P	S	N	S	S	V	V	A	W	N	K	Q	Q	G	G	Q	T	W	Y	V	V	F	N	G	A	V	Y	K	N	A	W	W	V	A	S	S	N	C	P	G	D	A	K	S	N	D	A	S	N	P	W	R	Y	V	R	A	A	T
Secondary structure
SS confidence
Disorder	?	?	?	?		?		?	?	?	?	?	?	?	?	?	?	?	?						?										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?								?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	A	T	E	I	S	E	T	S	N	P	Q	S	C	T	S	A	P	Q	P	S	P	D	V	K	P	A	P	D	V	K	P	A	P	D	V	Q	P	A	P	A	D	K	S	N	D	N	Y	A	V	V	A	W	K	G	Q	E	G	S	S	T
Secondary structure
SS confidence
Disorder	?	?		?	?					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?			?	?	?	?							?	?	?	?	?	?			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	W	Y	V	I	Y	N	G	G	I	Y	K	N	A	W	W	V	G	A	A	N	C	P	G	D	A	K	E	N	D	A	S	N	P	W	R	Y	V	R	A	A	T	A	T	E	I	S	Q	Y	G	N	P	G	S	C	S	V	K	P	D	N
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?	?	?	?	?												?	?	?	?	?	?			?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	N	G	G	A	V	T	P	V	D	P	T	P	E	T	P	V	T	P	T	P	D	N	S	E	P	S	T	P	A	D	S	V	N	D	Y	S	L	Q	A	W	S	G	Q	E	G	S	E	I	Y	H	V	I	F	N	G	N	V	Y	K	N
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?		?	?	?	?	?	?	?		?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?		?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	A	W	W	V	G	S	K	D	C	P	R	G	T	S	A	E	N	S	N	N	P	W	R	L	E	R	T	A	T	A	A	E	L	S	Q	Y	G	N	P	T	T	C	E	I	D	N	G	G	V	I	V	A	D	G	F	Q	A	S	K	A
Secondary structure
SS confidence
Disorder									?	?					?	?	?								?	?	?	?	?	?	?	?	?	?	?				?	?	?	?	?													?
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	Y	S	A	D	S	I	V	D	Y	N	D	A	H	Y	K	T	S	V	D	Q	D	A	W	G	F	V	P	G	G	D	N	P	W	K	K	Y	E	P	A	K	A	W	S	A	S	T	V	Y	V	K	G	D	R	V	V	V	D	G	Q	A
Secondary structure
SS confidence
Disorder																?				?	?		?	?							?				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	Y	E	A	L	F	W	T	Q	S	D	N	P	A	L	V	A	N	Q	N	A	T	G	S	N	S	R	P	W	K	P	L	G	K	A	Q	S	Y	S	N	E	E	L	N	N	A	P	Q	F	N	P	E	T	L	Y	A	S	D	T	L	I
Secondary structure
SS confidence
Disorder																						?			?								?	?	?				?	?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	R	F	N	G	V	N	Y	I	S	Q	S	K	V	Q	K	V	S	P	S	D	S	N	P	W	R	V	F	V	D	W	T	G	T	K	E	R	V	G	T	P	K	K	A	W	P	K	H	V	Y	A	P	Y	V	D	F	T	L	N	T	I
Secondary structure
SS confidence
Disorder	?													?			?	?	?	?	?								?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	P	D	L	A	A	L	A	K	N	H	N	V	N	H	F	T	L	A	F	V	V	S	K	D	A	N	T	C	L	P	T	W	G	T	A	Y	G	M	Q	N	Y	A	Q	Y	S	K	I	K	A	L	R	E	A	G	G	D	V	M	L	S
Secondary structure
SS confidence
Disorder			?																																	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	I	G	G	A	N	N	A	P	L	A	A	S	C	K	N	V	D	D	L	M	Q	H	Y	Y	D	I	V	D	N	L	N	L	K	V	L	D	F	D	I	E	G	T	W	V	A	D	Q	A	S	I	E	R	R	N	L	A	V	K	K	V
Secondary structure
SS confidence
Disorder											?		?																															?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	Q	D	K	W	K	S	E	G	K	D	I	A	I	W	Y	T	L	P	I	L	P	T	G	L	T	P	E	G	M	N	V	L	S	D	A	K	A	K	G	V	E	L	A	G	V	N	V	M	T	M	D	Y	G	N	A	I	C	Q	S	A
Secondary structure
SS confidence
Disorder																					?																																				?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	N	T	E	G	Q	N	I	H	G	K	C	A	T	S	A	I	A	N	L	H	S	Q	L	K	G	L	H	P	N	K	S	D	A	E	I	D	A	M	M	G	T	T	P	M	V	G	V	N	D	V	Q	G	E	V	F	Y	L	S	D	A
Secondary structure
SS confidence
Disorder	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.
Sequence	R	L	V	M	Q	D	A	Q	K	R	N	L	G	M	V	G	I	W	S	I	A	R	D	L	P	G	G	T	N	L	S	P	E	F	H	G	L	T	K	E	Q	A	P	K	Y	A	F	S	E	I	F	A	P	F	T	K	Q
Secondary structure
SS confidence
Disorder																										?		?	?								?	?	?	?	?	?										?	?	?	?	?	?
Disorder confidence