Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	F	D	P	T	G	Y	T	L	A	H	E	H	L	H	I	D	L	S	G	F	K	N	N	V	D	C	R	L	D	Q	Y	A	F	I	C	Q	E	M	N	D	L	M	T	R	G	V	R	N	V	I	E	M	T	N	R	Y	M	G
Secondary structure
SS confidence
Disorder		?	?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	N	A	Q	F	M	L	D	V	M	R	E	T	G	I	N	V	V	A	C	T	G	Y	Y	Q	D	A	F	F	P	E	H	V	A	T	R	S	V	Q	E	L	A	Q	E	M	V	D	E	I	E	Q	G	I	D	G	T	E	L	K	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	I	I	A	E	I	G	T	S	E	G	K	I	T	P	L	E	E	K	V	F	I	A	A	A	L	A	H	N	Q	T	G	R	P	I	S	T	H	T	S	F	S	T	M	G	L	E	Q	L	A	L	L	Q	A	H	G	V	D	L	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	V	T	V	G	H	C	D	L	K	D	N	L	D	N	I	L	K	M	I	D	L	G	A	Y	V	Q	F	D	T	I	G	K	N	S	Y	Y	P	D	E	K	R	I	A	M	L	H	A	L	R	D	R	G	L	L	N	R	V	M	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.
Sequence		S	M	D	I	T	R	R	S	H	L	K	A	N	G	G	Y	G	Y	D	Y	L	L	T	T	F	I	P	Q	L	R	Q	S	G	F	S	Q	A	D	V	D	V	M	L	R	E	N	P	S	Q	F	F	Q
Secondary structure
SS confidence
Disorder									?			?	?																																								?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1bf6 chain A Region: 2 - 292 Aligned: 291 Modelled: 291 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Phosphotriesterase-like Phyre2 PDB 3k2g chain A Region: 1 - 291 Aligned: 290 Modelled: 291 Confidence: 100.0% Identity: 32% PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides Phyre2 PDB 3f4c chain A Region: 1 - 291 Aligned: 289 Modelled: 291 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound Phyre2 PDB 3rhg chain A Region: 1 - 291 Aligned: 289 Modelled: 291 Confidence: 100.0% Identity: 31% PDB header:hydrolase Chain: A: PDB Molecule:putative phophotriesterase; PDBTitle: crystal structure of amidohydrolase pmi1525 (target efi-500319) from2 proteus mirabilis hi4320 Phyre2 PDB 2vc7 chain A Region: 1 - 291 Aligned: 289 Modelled: 291 Confidence: 100.0% Identity: 32% PDB header:hydrolase Chain: A: PDB Molecule:aryldialkylphosphatase; PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities Phyre2 PDB 2zc1 chain A Region: 1 - 291 Aligned: 289 Modelled: 291 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: organophosphorus hydrolase from deinococcus radiodurans Phyre2 PDB 3pnz chain D Region: 1 - 291 Aligned: 289 Modelled: 291 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes Phyre2 PDB 2d2j chain A domain 1 Region: 1 - 291 Aligned: 287 Modelled: 289 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Phosphotriesterase-like Phyre2 PDB 1i0d chain A Region: 1 - 291 Aligned: 287 Modelled: 291 Confidence: 100.0% Identity: 30% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Phosphotriesterase-like Phyre2 PDB 1psc chain A Region: 1 - 291 Aligned: 287 Modelled: 289 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: phosphotriesterase from pseudomonas diminuta Phyre2 PDB 2xio chain A Region: 6 - 291 Aligned: 263 Modelled: 286 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a Phyre2 PDB 2y1h chain A Region: 5 - 292 Aligned: 254 Modelled: 288 Confidence: 100.0% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) Phyre2 PDB 3ipw chain A Region: 5 - 291 Aligned: 262 Modelled: 287 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica Phyre2 PDB 3e2v chain A Region: 5 - 291 Aligned: 277 Modelled: 287 Confidence: 99.9% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae Phyre2 PDB 3msr chain A Region: 1 - 292 Aligned: 292 Modelled: 292 Confidence: 99.9% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolases; PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae Phyre2 PDB 1xwy chain A domain 1 Region: 8 - 292 Aligned: 252 Modelled: 285 Confidence: 99.9% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 1yix chain A domain 1 Region: 6 - 292 Aligned: 254 Modelled: 280 Confidence: 99.9% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 1j6o chain A Region: 8 - 291 Aligned: 249 Modelled: 283 Confidence: 99.9% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 1zzm chain A domain 1 Region: 8 - 292 Aligned: 252 Modelled: 272 Confidence: 99.9% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 2gzx chain B Region: 8 - 291 Aligned: 250 Modelled: 284 Confidence: 99.9% Identity: 14% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. Phyre2 1 d1bf6a_ 2 c3k2gA_ 3 c3f4cA_ 4 c3rhgA_ 5 c2vc7A_ 6 c2zc1A_ 7 c3pnzD_ 8 d2d2ja1 9 d1i0da_ 10 c1pscA_ 11 c2xioA_ 12 c2y1hA_ 13 c3ipwA_ 14 c3e2vA_ 15 c3msrA_ 16 d1xwya1 17 d1yixa1 18 d1j6oa_ 19 d1zzma1 20 c2gzxB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1bf6a_ 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 2 c3k2gA_ 100.0 32 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 3 c3f4cA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound 4 c3rhgA_ 100.0 31 PDB header:hydrolase Chain: A: PDB Molecule:putative phophotriesterase; PDBTitle: crystal structure of amidohydrolase pmi1525 (target efi-500319) from2 proteus mirabilis hi4320 5 c2vc7A_ 100.0 32 PDB header:hydrolase Chain: A: PDB Molecule:aryldialkylphosphatase; PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities 6 c2zc1A_ 100.0 29 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: organophosphorus hydrolase from deinococcus radiodurans 7 c3pnzD_ 100.0 29 PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes 8 d2d2ja1 100.0 31 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 9 d1i0da_ 100.0 30 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 10 c1pscA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: phosphotriesterase from pseudomonas diminuta 11 c2xioA_ 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a 12 c2y1hA_ 100.0 11 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) 13 c3ipwA_ 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica 14 c3e2vA_ 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae 15 c3msrA_ 99.9 25 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolases; PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae 16 d1xwya1 99.9 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 17 d1yixa1 99.9 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 18 d1j6oa_ 99.9 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 19 d1zzma1 99.9 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 20 c2gzxB_ 99.9 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. 21 c3rcmA_ not modelled 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida 22 c2qahA_ not modelled 99.9 11 PDB header:hydrolase Chain: A: PDB Molecule:2-pyrone-4,6-dicarboxylic acid hydrolase; PDBTitle: crystal structure of the 2-pyrone-4,6-dicarboxylic acid2 hydrolase from sphingomonas paucimobilis 23 d2ffia1 not modelled 99.9 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 24 c3irsB_ not modelled 99.9 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica 25 c3gg7A_ not modelled 99.9 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized metalloprotein; PDBTitle: crystal structure of an uncharacterized metalloprotein from2 deinococcus radiodurans 26 d2dvta1 not modelled 99.9 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 27 c3ij6A_ not modelled 99.9 11 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from lactobacillus acidophilus 28 d2gwga1 not modelled 99.9 10 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 29 c3guwB_ not modelled 99.9 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 30 c2wm1A_ not modelled 99.9 14 PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis 31 c3cjpA_ not modelled 99.8 15 PDB header:hydrolase Chain: A: PDB Molecule:predicted amidohydrolase, dihydroorotase family; PDBTitle: crystal structure of an uncharacterized amidohydrolase cac3332 from2 clostridium acetobutylicum 32 d2hbva1 not modelled 99.8 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 33 d2f6ka1 not modelled 99.8 10 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 34 c3nurA_ not modelled 99.8 11 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus 35 d1xrta2 not modelled 99.7 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 36 d1k1da2 not modelled 99.7 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 37 d1nfga2 not modelled 99.6 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 38 d1ynya2 not modelled 99.6 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 39 d1gkra2 not modelled 99.6 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 40 c3pnuA_ not modelled 99.6 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni. 41 d3be7a2 not modelled 99.5 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 42 d2icsa2 not modelled 99.5 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenine deaminase-like 43 d1kcxa2 not modelled 99.5 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 44 d2paja2 not modelled 99.5 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 45 d1onwa2 not modelled 99.5 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Isoaspartyl dipeptidase, catalytic domain 46 d2qs8a2 not modelled 99.5 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 47 d2uz9a2 not modelled 99.5 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 48 d2ftwa2 not modelled 99.5 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 49 c3jzeC_ not modelled 99.4 15 PDB header:hydrolase Chain: C: PDB Molecule:dihydroorotase; PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2 50 d2eg6a1 not modelled 99.4 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Dihydroorotase 51 d2i9ua2 not modelled 99.4 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 52 d2r8ca2 not modelled 99.4 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 53 c2qpxA_ not modelled 99.4 14 PDB header:hydrolase Chain: A: PDB Molecule:predicted metal-dependent hydrolase of the tim-barrel fold; PDBTitle: crystal structure of putative metal-dependent hydrolase (yp_805737.1)2 from lactobacillus casei atcc 334 at 1.40 a resolution 54 d1gkpa2 not modelled 99.4 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 55 d2fvka2 not modelled 99.4 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 56 d2p9ba2 not modelled 99.4 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 57 c1xrfA_ not modelled 99.3 17 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution 58 d1p1ma2 not modelled 99.3 10 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 59 c2pajA_ not modelled 99.3 14 PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/guanine deaminase; PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea 60 d2imra2 not modelled 99.3 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:DR0824-like 61 c2ogjB_ not modelled 99.2 13 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of a dihydroorotase 62 c3e0lB_ not modelled 99.2 10 PDB header:hydrolase Chain: B: PDB Molecule:guanine deaminase; PDBTitle: computationally designed ammelide deaminase 63 d2bb0a2 not modelled 99.1 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 64 c2vr2A_ not modelled 99.1 15 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase 65 d2puza2 not modelled 99.1 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 66 c3hpaB_ not modelled 99.1 15 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea 67 c2vunC_ not modelled 99.1 13 PDB header:hydrolase Chain: C: PDB Molecule:enamidase; PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily 68 d2ooda2 not modelled 99.1 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 69 c3gnhA_ not modelled 99.1 12 PDB header:hydrolase Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672; PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine. 70 c2aqoB_ not modelled 99.1 16 PDB header:hydrolase Chain: B: PDB Molecule:isoaspartyl dipeptidase; PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q 71 c3nqbB_ not modelled 99.1 12 PDB header:hydrolase Chain: B: PDB Molecule:adenine deaminase 2; PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58) 72 c3dc8B_ not modelled 99.1 12 PDB header:hydrolase Chain: B: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti 73 d2q09a2 not modelled 99.1 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 74 c1p1mA_ not modelled 99.1 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tm0936; PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine 75 c3itcA_ not modelled 99.0 16 PDB header:hydrolase Chain: A: PDB Molecule:renal dipeptidase; PDBTitle: crystal structure of sco3058 with bound citrate and glycerol 76 c1nfgA_ not modelled 99.0 18 PDB header:hydrolase Chain: A: PDB Molecule:d-hydantoinase; PDBTitle: structure of d-hydantoinase 77 c3lsbA_ not modelled 99.0 15 PDB header:hydrolase Chain: A: PDB Molecule:triazine hydrolase; PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin 78 c2ftwA_ not modelled 99.0 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase; PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum 79 c2q09A_ not modelled 99.0 13 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid 80 c2bb0A_ not modelled 99.0 11 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: structure of imidazolonepropionase from bacillus subtilis 81 c2i9uA_ not modelled 99.0 12 PDB header:hydrolase Chain: A: PDB Molecule:cytosine/guanine deaminase related protein; PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site 82 c2gseC_ not modelled 99.0 13 PDB header:hydrolase Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2; PDBTitle: crystal structure of human dihydropyrimidinease-like 2 83 c1gkpD_ not modelled 99.0 13 PDB header:hydrolase Chain: D: PDB Molecule:hydantoinase; PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221 84 c3d6nA_ not modelled 99.0 15 PDB header:hydrolase/transferase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 85 c3lnpA_ not modelled 99.0 11 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465; PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica 86 c1k1dF_ not modelled 98.9 15 PDB header:hydrolase Chain: F: PDB Molecule:d-hydantoinase; PDBTitle: crystal structure of d-hydantoinase 87 c2icsA_ not modelled 98.9 16 PDB header:hydrolase Chain: A: PDB Molecule:adenine deaminase; PDBTitle: crystal structure of an adenine deaminase 88 c2imrA_ not modelled 98.9 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dr_0824; PDBTitle: crystal structure of amidohydrolase dr_0824 from2 deinococcus radiodurans 89 c1gkrA_ not modelled 98.9 18 PDB header:hydrolase Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase; PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens 90 c2fvmA_ not modelled 98.9 16 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine 91 c2gokA_ not modelled 98.9 12 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution 92 d1o12a2 not modelled 98.9 10 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain 93 d1ra0a2 not modelled 98.9 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Cytosine deaminase catalytic domain 94 d4ubpc2 not modelled 98.9 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain 95 d1itua_ not modelled 98.9 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Renal dipeptidase 96 c3be7B_ not modelled 98.9 12 PDB header:hydrolase Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase; PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase 97 c3fdgA_ not modelled 98.8 12 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidase ac. metallo peptidase. merops family m19; PDBTitle: the crystal structure of the dipeptidase ac, metallo peptidase. merops2 family m19 98 d1m7ja3 not modelled 98.8 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:D-aminoacylase, catalytic domain 99 c2i5gB_ not modelled 98.8 14 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal strcuture of amidohydrolase from pseudomonas2 aeruginosa 100 c3hm7A_ not modelled 98.8 12 PDB header:hydrolase Chain: A: PDB Molecule:allantoinase; PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125 101 c2ragB_ not modelled 98.7 15 PDB header:hydrolase Chain: B: PDB Molecule:dipeptidase; PDBTitle: crystal structure of aminohydrolase from caulobacter crescentus 102 c3mduA_ not modelled 98.7 18 PDB header:hydrolase Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase; PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate 103 c1r9yA_ not modelled 98.7 11 PDB header:hydrolase Chain: A: PDB Molecule:cytosine deaminase; PDBTitle: bacterial cytosine deaminase d314a mutant. 104 c2gwnA_ not modelled 98.7 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the structure of putative dihydroorotase from porphyromonas2 gingivalis. 105 c3ooqC_ not modelled 98.7 14 PDB header:hydrolase Chain: C: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of amidohydrolase from thermotoga maritima msb8 106 c2qs8A_ not modelled 98.7 11 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of a xaa-pro dipeptidase with bound2 methionine in the active site 107 c2p50C_ not modelled 98.7 12 PDB header:hydrolase Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn 108 c3lu2B_ not modelled 98.7 11 PDB header:hydrolase Chain: B: PDB Molecule:lmo2462 protein; PDBTitle: structure of lmo2462, a listeria monocytogenes amidohydrolase family2 putative dipeptidase 109 c3b40A_ not modelled 98.6 17 PDB header:hydrolase Chain: A: PDB Molecule:probable dipeptidase; PDBTitle: crystal structure of the probable dipeptidase pvdm from2 pseudomonas aeruginosa 110 c3mpgB_ not modelled 98.6 15 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: dihydroorotase from bacillus anthracis 111 c2z00A_ not modelled 98.6 16 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of dihydroorotase from thermus thermophilus 112 c3e74D_ not modelled 98.6 13 PDB header:hydrolase Chain: D: PDB Molecule:allantoinase; PDBTitle: crystal structure of e. coli allantoinase with iron ions at2 the metal center 113 c2qt3A_ not modelled 98.6 8 PDB header:hydrolase Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase; PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn 114 c2r8cB_ not modelled 98.6 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative amidohydrolase; PDBTitle: crystal structure of uncharacterized protein eaj56179 115 c3griB_ not modelled 98.5 13 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a dihydroorotase from staphylococcus aureus 116 c2wjeA_ not modelled 98.5 14 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase cpsb; PDBTitle: crystal structure of the tyrosine phosphatase cps4b from2 steptococcus pneumoniae tigr4. 117 c3feqB_ not modelled 98.5 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative amidohydrolase; PDBTitle: crystal structure of uncharacterized protein eah89906 118 c2p9bA_ not modelled 98.5 12 PDB header:hydrolase Chain: A: PDB Molecule:possible prolidase; PDBTitle: crystal structure of putative prolidase from2 bifidobacterium longum 119 c2oodA_ not modelled 98.4 11 PDB header:hydrolase Chain: A: PDB Molecule:blr3880 protein; PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum 120 d1j5sa_ not modelled 98.3 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Uronate isomerase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0