Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	V	D	L	L	G	S	A	Q	S	A	H	A	L	H	L	F	H	Q	H	S	P	L	V	H	C	M	T	N	D	V	V	Q	T	F	T	A	N	T	L	L	A	L	G	A	S	P	A	M	V	I	E	T	E	E	A	S	Q	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	A	I	A	S	A	L	L	I	N	V	G	T	L	T	Q	P	R	A	Q	A	M	R	A	A	V	E	Q	A	K	S	S	Q	T	P	W	T	L	D	P	V	A	V	G	A	L	D	Y	R	R	H	F	C	H	E	L	L	S	F	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	A	A	I	R	G	N	A	S	E	I	M	A	L	A	G	I	A	N	G	G	R	G	V	D	T	T	D	A	A	A	N	A	I	P	A	A	Q	T	L	A	R	E	T	G	A	I	V	V	V	T	G	E	M	D	Y	V	T	D	G
Secondary structure
SS confidence
Disorder																		?	?	?	?	?								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	R	I	I	G	I	H	G	G	D	P	L	M	T	K	V	V	G	T	G	C	A	L	S	A	V	V	A	A	C	C	A	L	P	G	D	T	L	E	N	V	A	S	A	C	H	W	M	K	Q	A	G	E	R	A	V	A	R	S	E
Secondary structure
SS confidence
Disorder																																																											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.
Sequence		G	P	G	S	F	V	P	H	F	L	D	A	L	W	Q	L	T	Q	E	V	Q	A
Secondary structure
SS confidence
Disorder		?	?	?													?	?			?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3dzv chain B Region: 20 - 259 Aligned: 240 Modelled: 237 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: B: PDB Molecule:4-methyl-5-(beta-hydroxyethyl)thiazole kinase; PDBTitle: crystal structure of 4-methyl-5-(beta-hydroxyethyl)thiazole2 kinase (np_816404.1) from enterococcus faecalis v583 at3 2.57 a resolution Phyre2 PDB 1ekq chain A Region: 9 - 260 Aligned: 237 Modelled: 238 Confidence: 100.0% Identity: 41% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: Thiamin biosynthesis kinases Phyre2 PDB 1v8a chain A Region: 10 - 259 Aligned: 240 Modelled: 250 Confidence: 100.0% Identity: 38% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: Thiamin biosynthesis kinases Phyre2 PDB 3nm3 chain D Region: 4 - 259 Aligned: 241 Modelled: 245 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme; PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes Phyre2 PDB 3bgk chain A Region: 14 - 261 Aligned: 231 Modelled: 242 Confidence: 100.0% Identity: 20% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: the crystal structure of hypothetic protein smu.573 from2 streptococcus mutans Phyre2 PDB 1kyh chain A Region: 14 - 261 Aligned: 224 Modelled: 239 Confidence: 100.0% Identity: 16% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: YjeF C-terminal domain-like Phyre2 PDB 2r3b chain A Region: 14 - 261 Aligned: 230 Modelled: 248 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:yjef-related protein; PDBTitle: crystal structure of a ribokinase-like superfamily protein (ef1790)2 from enterococcus faecalis v583 at 1.80 a resolution Phyre2 PDB 2ax3 chain A domain 1 Region: 1 - 261 Aligned: 230 Modelled: 237 Confidence: 100.0% Identity: 17% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: YjeF C-terminal domain-like Phyre2 PDB 2ax3 chain A Region: 1 - 261 Aligned: 230 Modelled: 237 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:hypothetical protein tm0922; PDBTitle: crystal structure of a putative carbohydrate kinase (tm0922) from2 thermotoga maritima msb8 at 2.25 a resolution Phyre2 PDB 3k5w chain A Region: 62 - 256 Aligned: 174 Modelled: 188 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:carbohydrate kinase; PDBTitle: crystal structure of a carbohydrate kinase (yjef family)from2 helicobacter pylori Phyre2 PDB 3rm5 chain B Region: 55 - 243 Aligned: 181 Modelled: 189 Confidence: 99.9% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:hydroxymethylpyrimidine/phosphomethylpyrimidine kinase PDBTitle: structure of trifunctional thi20 from yeast Phyre2 PDB 3mbj chain A Region: 68 - 253 Aligned: 180 Modelled: 186 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:putative phosphomethylpyrimidine kinase; PDBTitle: crystal structure of a putative phosphomethylpyrimidine kinase2 (bt_4458) from bacteroides thetaiotaomicron vpi-5482 at 2.10 a3 resolution (rhombohedral form) Phyre2 PDB 3ibq chain A Region: 65 - 258 Aligned: 185 Modelled: 194 Confidence: 99.9% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:pyridoxal kinase; PDBTitle: crystal structure of pyridoxal kinase from lactobacillus2 plantarum in complex with atp Phyre2 PDB 1jxh chain A Region: 55 - 244 Aligned: 176 Modelled: 190 Confidence: 99.8% Identity: 20% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: Thiamin biosynthesis kinases Phyre2 PDB 1vi9 chain A Region: 46 - 239 Aligned: 185 Modelled: 184 Confidence: 99.8% Identity: 19% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: PfkB-like kinase Phyre2 PDB 1ub0 chain A Region: 54 - 243 Aligned: 177 Modelled: 190 Confidence: 99.8% Identity: 25% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: Thiamin biosynthesis kinases Phyre2 PDB 2i5b chain C Region: 55 - 245 Aligned: 182 Modelled: 189 Confidence: 99.8% Identity: 20% PDB header:transferase Chain: C: PDB Molecule:phosphomethylpyrimidine kinase; PDBTitle: the crystal structure of an adp complex of bacillus2 subtilis pyridoxal kinase provides evidence for the3 parralel emergence of enzyme activity during evolution Phyre2 PDB 1lhp chain A Region: 44 - 237 Aligned: 185 Modelled: 194 Confidence: 99.8% Identity: 18% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: PfkB-like kinase Phyre2 PDB 2ddm chain A Region: 62 - 241 Aligned: 170 Modelled: 180 Confidence: 99.7% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:pyridoxine kinase; PDBTitle: crystal structure of pyridoxal kinase from the escherichia2 coli pdxk gene at 2.1 a resolution Phyre2 PDB 2f02 chain A domain 1 Region: 54 - 255 Aligned: 185 Modelled: 201 Confidence: 99.6% Identity: 15% Fold: Ribokinase-like Superfamily: Ribokinase-like Family: Ribokinase-like Phyre2 1 c3dzvB_ 2 d1ekqa_ 3 d1v8aa_ 4 c3nm3D_ 5 c3bgkA_ 6 d1kyha_ 7 c2r3bA_ 8 d2ax3a1 9 c2ax3A_ 10 c3k5wA_ 11 c3rm5B_ 12 c3mbjA_ 13 c3ibqA_ 14 d1jxha_ 15 d1vi9a_ 16 d1ub0a_ 17 c2i5bC_ 18 d1lhpa_ 19 c2ddmA_ 20 d2f02a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3dzvB_ 100.0 26 PDB header:transferase Chain: B: PDB Molecule:4-methyl-5-(beta-hydroxyethyl)thiazole kinase; PDBTitle: crystal structure of 4-methyl-5-(beta-hydroxyethyl)thiazole2 kinase (np_816404.1) from enterococcus faecalis v583 at3 2.57 a resolution 2 d1ekqa_ 100.0 41 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Thiamin biosynthesis kinases 3 d1v8aa_ 100.0 38 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Thiamin biosynthesis kinases 4 c3nm3D_ 100.0 33 PDB header:transferase Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme; PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes 5 c3bgkA_ 100.0 20 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: the crystal structure of hypothetic protein smu.573 from2 streptococcus mutans 6 d1kyha_ 100.0 16 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:YjeF C-terminal domain-like 7 c2r3bA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:yjef-related protein; PDBTitle: crystal structure of a ribokinase-like superfamily protein (ef1790)2 from enterococcus faecalis v583 at 1.80 a resolution 8 d2ax3a1 100.0 17 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:YjeF C-terminal domain-like 9 c2ax3A_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein tm0922; PDBTitle: crystal structure of a putative carbohydrate kinase (tm0922) from2 thermotoga maritima msb8 at 2.25 a resolution 10 c3k5wA_ 99.9 15 PDB header:transferase Chain: A: PDB Molecule:carbohydrate kinase; PDBTitle: crystal structure of a carbohydrate kinase (yjef family)from2 helicobacter pylori 11 c3rm5B_ 99.9 20 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylpyrimidine/phosphomethylpyrimidine kinase PDBTitle: structure of trifunctional thi20 from yeast 12 c3mbjA_ 99.9 16 PDB header:transferase Chain: A: PDB Molecule:putative phosphomethylpyrimidine kinase; PDBTitle: crystal structure of a putative phosphomethylpyrimidine kinase2 (bt_4458) from bacteroides thetaiotaomicron vpi-5482 at 2.10 a3 resolution (rhombohedral form) 13 c3ibqA_ 99.9 21 PDB header:transferase Chain: A: PDB Molecule:pyridoxal kinase; PDBTitle: crystal structure of pyridoxal kinase from lactobacillus2 plantarum in complex with atp 14 d1jxha_ 99.8 20 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Thiamin biosynthesis kinases 15 d1vi9a_ 99.8 19 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:PfkB-like kinase 16 d1ub0a_ 99.8 25 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Thiamin biosynthesis kinases 17 c2i5bC_ 99.8 20 PDB header:transferase Chain: C: PDB Molecule:phosphomethylpyrimidine kinase; PDBTitle: the crystal structure of an adp complex of bacillus2 subtilis pyridoxal kinase provides evidence for the3 parralel emergence of enzyme activity during evolution 18 d1lhpa_ 99.8 18 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:PfkB-like kinase 19 c2ddmA_ 99.7 19 PDB header:transferase Chain: A: PDB Molecule:pyridoxine kinase; PDBTitle: crystal structure of pyridoxal kinase from the escherichia2 coli pdxk gene at 2.1 a resolution 20 d2f02a1 99.6 15 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 21 c3cqdB_ not modelled 99.5 13 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructokinase isozyme 2; PDBTitle: structure of the tetrameric inhibited form of2 phosphofructokinase-2 from escherichia coli 22 c2jg1C_ not modelled 99.5 16 PDB header:transferase Chain: C: PDB Molecule:tagatose-6-phosphate kinase; PDBTitle: structure of staphylococcus aureus d-tagatose-6-phosphate2 kinase with cofactor and substrate 23 c2jg5B_ not modelled 99.4 12 PDB header:transferase Chain: B: PDB Molecule:fructose 1-phosphate kinase; PDBTitle: crystal structure of a putative phosphofructokinase from2 staphylococcus aureus 24 d2abqa1 not modelled 99.4 20 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 25 d1bx4a_ not modelled 99.4 11 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 26 c3looC_ not modelled 99.4 14 PDB header:transferase Chain: C: PDB Molecule:anopheles gambiae adenosine kinase; PDBTitle: crystal structure of anopheles gambiae adenosine kinase in complex2 with p1,p4-di(adenosine-5) tetraphosphate 27 c2xtbA_ not modelled 99.3 10 PDB header:transferase Chain: A: PDB Molecule:adenosine kinase; PDBTitle: crystal structure of trypanosoma brucei rhodesiense2 adenosine kinase complexed with activator 28 c3kzhA_ not modelled 99.3 17 PDB header:transferase Chain: A: PDB Molecule:probable sugar kinase; PDBTitle: crystal structure of a putative sugar kinase from2 clostridium perfringens 29 c2rbcA_ not modelled 99.3 15 PDB header:transferase Chain: A: PDB Molecule:sugar kinase; PDBTitle: crystal structure of a putative ribokinase from agrobacterium2 tumefaciens 30 c3ktnA_ not modelled 99.2 14 PDB header:transferase Chain: A: PDB Molecule:carbohydrate kinase, pfkb family; PDBTitle: crystal structure of a putative 2-keto-3-deoxygluconate2 kinase from enterococcus faecalis 31 c2qcvA_ not modelled 99.2 11 PDB header:transferase Chain: A: PDB Molecule:putative 5-dehydro-2-deoxygluconokinase; PDBTitle: crystal structure of a putative 5-dehydro-2-deoxygluconokinase (iolc)2 from bacillus halodurans c-125 at 1.90 a resolution 32 c2absA_ not modelled 99.2 14 PDB header:signaling protein,transferase Chain: A: PDB Molecule:adenosine kinase; PDBTitle: crystal structure of t. gondii adenosine kinase complexed2 with amp-pcp 33 d2absa1 not modelled 99.2 14 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 34 d2afba1 not modelled 99.2 12 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 35 c3pl2D_ not modelled 99.2 12 PDB header:transferase Chain: D: PDB Molecule:sugar kinase, ribokinase family; PDBTitle: crystal structure of a 5-keto-2-deoxygluconokinase (ncgl0155, cgl0158)2 from corynebacterium glutamicum atcc 13032 kitasato at 1.89 a3 resolution 36 c2pkkA_ not modelled 99.2 14 PDB header:transferase Chain: A: PDB Molecule:adenosine kinase; PDBTitle: crystal structure of m tuberculosis adenosine kinase complexed with 2-2 fluro adenosine 37 d2ajra1 not modelled 99.2 14 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 38 d1rkda_ not modelled 99.1 21 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 39 c3iq0B_ not modelled 99.1 13 PDB header:transferase Chain: B: PDB Molecule:putative ribokinase ii; PDBTitle: crystal structure of a putative ribokinase ii in complex2 with atp and mg+2 from e.coli 40 c2qhpA_ not modelled 99.1 12 PDB header:transferase Chain: A: PDB Molecule:fructokinase; PDBTitle: crystal structure of fructokinase (np_810670.1) from bacteroides2 thetaiotaomicron vpi-5482 at 1.80 a resolution 41 c3lhxA_ not modelled 99.1 9 PDB header:transferase Chain: A: PDB Molecule:ketodeoxygluconokinase; PDBTitle: crystal structure of a ketodeoxygluconokinase (kdgk) from2 shigella flexneri 42 c2nwhA_ not modelled 99.1 15 PDB header:signaling protein,transferase Chain: A: PDB Molecule:carbohydrate kinase; PDBTitle: carbohydrate kinase from agrobacterium tumefaciens 43 d1v19a_ not modelled 99.1 14 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 44 d1vm7a_ not modelled 99.0 16 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 45 c3julA_ not modelled 99.0 10 PDB header:transferase Chain: A: PDB Molecule:lin2199 protein; PDBTitle: crystal structure of listeria innocua d-tagatose-6-phosphate2 kinase bound with substrate 46 c3in1A_ not modelled 99.0 16 PDB header:transferase Chain: A: PDB Molecule:uncharacterized sugar kinase ydjh; PDBTitle: crystal structure of a putative ribokinase in complex with2 adp from e.coli 47 c3b1qD_ not modelled 99.0 14 PDB header:transferase Chain: D: PDB Molecule:ribokinase, putative; PDBTitle: structure of burkholderia thailandensis nucleoside kinase (bthnk) in2 complex with inosine 48 c2varB_ not modelled 99.0 11 PDB header:transferase Chain: B: PDB Molecule:fructokinase; PDBTitle: crystal structure of sulfolobus solfataricus 2-keto-3-2 deoxygluconate kinase complexed with 2-keto-3-3 deoxygluconate 49 d2dcna1 not modelled 98.9 16 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 50 d1vk4a_ not modelled 98.9 10 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 51 c2c49A_ not modelled 98.9 11 PDB header:transferase Chain: A: PDB Molecule:sugar kinase mj0406; PDBTitle: crystal structure of methanocaldococcus jannaschii2 nucleoside kinase - an archaeal member of the ribokinase3 family 52 c3go6B_ not modelled 98.8 14 PDB header:transferase Chain: B: PDB Molecule:ribokinase rbsk; PDBTitle: crystal structure of m. tuberculosis ribokinase (rv2436) in2 complex with ribose and amp-pnp 53 c3bf5A_ not modelled 98.8 11 PDB header:transferase Chain: A: PDB Molecule:ribokinase related protein; PDBTitle: crystal structure of putative ribokinase (10640157) from thermoplasma2 acidophilum at 1.91 a resolution 54 d1tyya_ not modelled 98.8 11 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 55 c1tz6B_ not modelled 98.8 11 PDB header:transferase Chain: B: PDB Molecule:putative sugar kinase; PDBTitle: crystal structure of aminoimidazole riboside kinase from2 salmonella enterica complexed with aminoimidazole riboside3 and atp analog 56 d2fv7a1 not modelled 98.7 16 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 57 c3hj6B_ not modelled 98.7 17 PDB header:transferase Chain: B: PDB Molecule:fructokinase; PDBTitle: structure of halothermothrix orenii fructokinase (frk) 58 c3i3yB_ not modelled 98.6 14 PDB header:transferase Chain: B: PDB Molecule:carbohydrate kinase; PDBTitle: crystal structure of ribokinase in complex with d-ribose from2 klebsiella pneumoniae 59 c3kd6B_ not modelled 98.6 14 PDB header:transferase Chain: B: PDB Molecule:carbohydrate kinase, pfkb family; PDBTitle: crystal structure of nucleoside kinase from chlorobium tepidum in2 complex with amp 60 c3b3lC_ not modelled 98.5 14 PDB header:transferase Chain: C: PDB Molecule:ketohexokinase; PDBTitle: crystal structures of alternatively-spliced isoforms of human2 ketohexokinase 61 c3gbuD_ not modelled 98.5 9 PDB header:transferase Chain: D: PDB Molecule:uncharacterized sugar kinase ph1459; PDBTitle: crystal structure of an uncharacterized sugar kinase ph1459 from2 pyrococcus horikoshii in complex with atp 62 c3lkiA_ not modelled 98.3 13 PDB header:transferase Chain: A: PDB Molecule:fructokinase; PDBTitle: crystal structure of fructokinase with bound atp from2 xylella fastidiosa 63 c3pm6B_ not modelled 91.4 23 PDB header:lyase Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase; PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr 64 c1tx2A_ not modelled 86.1 15 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 65 d1tx2a_ not modelled 86.1 15 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 66 c2iswB_ not modelled 86.0 16 PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate 67 c3q94B_ not modelled 85.9 15 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor' 68 d1gvfa_ not modelled 84.8 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 69 d1ad1a_ not modelled 84.3 21 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 70 c3tr9A_ not modelled 83.6 13 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii 71 c3c52B_ not modelled 80.1 20 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor 72 d1rvga_ not modelled 78.4 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 73 c2vp8A_ not modelled 78.3 22 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase 2; PDBTitle: structure of mycobacterium tuberculosis rv1207 74 d2aeua1 not modelled 74.3 11 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:SelA-like 75 d1a9xb2 not modelled 73.6 9 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 76 d1f6ya_ not modelled 73.0 20 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Methyltetrahydrofolate-utiluzing methyltransferases 77 c3bolB_ not modelled 72.3 17 PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ 78 c2dzaA_ not modelled 71.0 23 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate 79 c3fokH_ not modelled 71.0 21 PDB header:structural genomics, unknown function Chain: H: PDB Molecule:uncharacterized protein cgl0159; PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115 80 c2w7tA_ not modelled 70.9 15 PDB header:ligase Chain: A: PDB Molecule:putative cytidine triphosphate synthase; PDBTitle: trypanosoma brucei ctps - glutaminase domain with bound2 acivicin 81 c3gndC_ not modelled 70.3 12 PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate 82 c3elfA_ not modelled 70.3 17 PDB header:lyase Chain: A: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase 83 d1ajza_ not modelled 70.2 15 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 84 d2jfga1 not modelled 69.7 9 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 85 c3hl2D_ not modelled 69.3 4 PDB header:transferase Chain: D: PDB Molecule:o-phosphoseryl-trna(sec) selenium transferase; PDBTitle: the crystal structure of the human sepsecs-trnasec complex 86 d1dosa_ not modelled 68.7 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 87 c1zfjA_ not modelled 67.9 23 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 88 c3cf4G_ not modelled 66.9 16 PDB header:oxidoreductase Chain: G: PDB Molecule:acetyl-coa decarboxylase/synthase epsilon subunit; PDBTitle: structure of the codh component of the m. barkeri acds complex 89 c2qcnA_ not modelled 63.1 21 PDB header:lyase Chain: A: PDB Molecule:uridine 5'-monophosphate synthase; PDBTitle: covalent complex of the orotidine-5'-monophosphate decarboxylase2 domain of human ump synthase with 6-iodo-ump 90 d1eyea_ not modelled 62.8 25 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 91 d3bofa1 not modelled 62.7 21 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Methyltetrahydrofolate-utiluzing methyltransferases 92 d1p3da1 not modelled 62.6 12 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 93 c2h9aB_ not modelled 62.2 9 PDB header:oxidoreductase Chain: B: PDB Molecule:co dehydrogenase/acetyl-coa synthase, iron- PDBTitle: corrinoid iron-sulfur protein 94 c2yciX_ not modelled 62.0 24 PDB header:transferase Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein PDBTitle: methyltransferase native 95 c3bvjA_ not modelled 60.8 21 PDB header:lyase Chain: A: PDB Molecule:uridine 5'-monophosphate synthase; PDBTitle: crystal structure of human orotidine 5'-monophosphate decarboxylase2 complexed with xmp 96 c2l2qA_ not modelled 60.6 11 PDB header:transferase Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela); PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi 97 c3ndnC_ not modelled 59.9 11 PDB header:lyase Chain: C: PDB Molecule:o-succinylhomoserine sulfhydrylase; PDBTitle: crystal structure of o-succinylhomoserine sulfhydrylase from2 mycobacterium tuberculosis covalently bound to pyridoxal-5-phosphate 98 c3qm3C_ not modelled 58.5 9 PDB header:lyase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni 99 c2ad5B_ not modelled 57.1 14 PDB header:ligase Chain: B: PDB Molecule:ctp synthase; PDBTitle: mechanisms of feedback regulation and drug resistance of ctp2 synthetases: structure of the e. coli ctps/ctp complex at 2.8-3 angstrom resolution. 100 d1j6ua1 not modelled 57.0 7 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 101 c1vcnA_ not modelled 55.7 14 PDB header:ligase Chain: A: PDB Molecule:ctp synthetase; PDBTitle: crystal structure of t.th. hb8 ctp synthetase complex with sulfate2 anion 102 d1to3a_ not modelled 53.3 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 103 d1pkla2 not modelled 52.0 9 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 104 d1ex2a_ not modelled 51.9 19 Fold:Anticodon-binding domain-like Superfamily:ITPase-like Family:Maf-like 105 c1kczA_ not modelled 51.1 14 PDB header:lyase Chain: A: PDB Molecule:beta-methylaspartase; PDBTitle: crystal structure of beta-methylaspartase from clostridium2 tetanomorphum. mg-complex. 106 d1c7ga_ not modelled 51.0 14 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Beta-eliminating lyases 107 c3noyA_ not modelled 50.8 19 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: crystal structure of ispg (gcpe) 108 c2y0fD_ not modelled 50.7 18 PDB header:oxidoreductase Chain: D: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: structure of gcpe (ispg) from thermus thermophilus hb27 109 c1w25B_ not modelled 50.5 14 PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp 110 c3m84A_ not modelled 50.1 14 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylformylglycinamidine cyclo-ligase; PDBTitle: crystal structure of phosphoribosylaminoimidazole synthetase from2 francisella tularensis 111 d2f9ya1 not modelled 49.3 14 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 112 c2z01A_ not modelled 47.5 13 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylformylglycinamidine cyclo-ligase; PDBTitle: crystal structure of phosphoribosylaminoimidazole2 synthetase from geobacillus kaustophilus 113 d1pxya_ not modelled 47.4 16 Fold:CH domain-like Superfamily:Calponin-homology domain, CH-domain Family:Calponin-homology domain, CH-domain 114 d1liua2 not modelled 47.3 10 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 115 c3nvaB_ not modelled 47.1 13 PDB header:ligase Chain: B: PDB Molecule:ctp synthase; PDBTitle: dimeric form of ctp synthase from sulfolobus solfataricus 116 c1kkoB_ not modelled 46.1 14 PDB header:lyase Chain: B: PDB Molecule:3-methylaspartate ammonia-lyase; PDBTitle: crystal structure of citrobacter amalonaticus2 methylaspartate ammonia lyase 117 d1vcoa1 not modelled 45.3 13 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 118 c3cwcB_ not modelled 44.5 14 PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 119 d1rt8a_ not modelled 43.1 19 Fold:CH domain-like Superfamily:Calponin-homology domain, CH-domain Family:Calponin-homology domain, CH-domain 120 d2q8za1 not modelled 42.7 10 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0