PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2i5bC_

Fold library id	PDB Header	Molecule	Title
c2i5bC_	PDB header: transferase	Chain: C: PDB Molecule: phosphomethylpyrimidine kinase;	PDBTitle: the crystal structure of an adp complex of bacillus2 subtilis pyridoxal kinase provides evidence for the3 parralel emergence of enzyme activity during evolution

Links to external resources
Added to library: Tue Mar 16 12:47:38 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M H K A L T I A G S D S S G G A G I Q A D L K T F Q E K N V Y G M T A L T V I V A M D P N N S W N H Q V F P I D T D T I R A Q L A T I T D G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S S T T
T T T T T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I G V D A M K T G M L P T V D I I E L A A K T I K E K Q L K N V V I D P V M V C K G A N E V L Y P E H A Q A L R E Q L A P L A T V I T P N L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
S
S T T
S S
S S B
S S S B S
T G G G
S
B

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence F E A S Q L S G M D E L K T V D D M I E A A K K I H A L G A Q Y V V I T G G G K L K H E K A V D V L Y D G E T A E V L E S E M I D T P Y T H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S T T T
S
G G G S
S S S
S S
S
B

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . .

Sequence G A G C T F S A A V T A E L A K G A E V K E A I Y A A K E F I T A A I K E S F P L N Q Y V G P T K H S A L R L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
T
S S S S
B
T T T T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	H	K	A	L	T	I	A	G	S	D	S	S	G	G	A	G	I	Q	A	D	L	K	T	F	Q	E	K	N	V	Y	G	M	T	A	L	T	V	I	V	A	M	D	P	N	N	S	W	N	H	Q	V	F	P	I	D	T	D	T	I	R	A	Q	L	A	T	I	T	D	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T	T	S	S	S												T	T															T	T	T	T	T																					T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	G	V	D	A	M	K	T	G	M	L	P	T	V	D	I	I	E	L	A	A	K	T	I	K	E	K	Q	L	K	N	V	V	I	D	P	V	M	V	C	K	G	A	N	E	V	L	Y	P	E	H	A	Q	A	L	R	E	Q	L	A	P	L	A	T	V	I	T	P	N	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S			S									S														T	T		S	S								S	S	B		S	S	S	B	S												T	G	G	G		S					B
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	F	E	A	S	Q	L	S	G	M	D	E	L	K	T	V	D	D	M	I	E	A	A	K	K	I	H	A	L	G	A	Q	Y	V	V	I	T	G	G	G	K	L	K	H	E	K	A	V	D	V	L	Y	D	G	E	T	A	E	V	L	E	S	E	M	I	D	T	P	Y	T	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T						S													T	T	T		S							G	G	G	S		S	S	S								S	S													S			B
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.
Sequence	G	A	G	C	T	F	S	A	A	V	T	A	E	L	A	K	G	A	E	V	K	E	A	I	Y	A	A	K	E	F	I	T	A	A	I	K	E	S	F	P	L	N	Q	Y	V	G	P	T	K	H	S	A	L	R	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T															T	T																				T				S	S	S	S			B			T	T	T	T	T