Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A786
DateThu Jan 5 11:05:04 GMT 2012
Unique Job ID8c5fc03d5ec8217b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1tuga1
Top template information
Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
Confidence and coverage
Confidence:100.0% Coverage:100%
310 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSF
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Disorder  ???????

























?
???





















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   .........70.........80.........90.........100.........110.........120
Sequence  ETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFS
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Disorder 















??????????

































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   .........130.........140.........150.........160.........170.........180
Sequence  GNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKF
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   .........190.........200.........210.........220.........230.........240
Sequence  DGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSE
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??????


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   .........250.........260.........270.........280.........290.........300
Sequence  YANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQAL
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   .........310.
Sequence  LALVLNRDLVL
Secondary structure 





SS confidence 










Disorder 




?

???
Disorder confidence 










 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1tug chain A domain 1

3D model

Region: 2 - 311
Aligned: 310
Modelled: 310
Confidence: 100.0%
Identity: 100%
Fold: ATC-like
Superfamily: Aspartate/ornithine carbamoyltransferase
Family: Aspartate/ornithine carbamoyltransferase

Phyre2

PDB 1ml4 chain A

3D model

Region: 4 - 307
Aligned: 301
Modelled: 304
Confidence: 100.0%
Identity: 52%
PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi

Phyre2

PDB 1pg5 chain A

3D model

Region: 8 - 307
Aligned: 287
Modelled: 300
Confidence: 100.0%
Identity: 45%
PDB header:transferase
Chain: A: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius

Phyre2

PDB 2rgw chain D

3D model

Region: 8 - 306
Aligned: 291
Modelled: 299
Confidence: 100.0%
Identity: 48%
PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase

Phyre2

PDB 2w37 chain A

3D model

Region: 2 - 307
Aligned: 300
Modelled: 305
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic;
PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii

Phyre2

PDB 2otc chain A

3D model

Region: 3 - 307
Aligned: 299
Modelled: 298
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine

Phyre2

PDB 3upd chain A

3D model

Region: 1 - 306
Aligned: 300
Modelled: 305
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus

Phyre2

PDB 1vlv chain A

3D model

Region: 1 - 305
Aligned: 291
Modelled: 304
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution

Phyre2

PDB 1ort chain D

3D model

Region: 2 - 306
Aligned: 299
Modelled: 305
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: D: PDB Molecule:ornithine transcarbamoylase;
PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa

Phyre2

PDB 1fvo chain B

3D model

Region: 2 - 306
Aligned: 298
Modelled: 299
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: B: PDB Molecule:ornithine transcarbamylase;
PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate

Phyre2

PDB 1a1s chain A

3D model

Region: 4 - 307
Aligned: 297
Modelled: 301
Confidence: 100.0%
Identity: 29%
PDB header:transcarbamylase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus

Phyre2

PDB 3lxm chain C

3D model

Region: 3 - 308
Aligned: 277
Modelled: 287
Confidence: 100.0%
Identity: 82%
PDB header:transferase
Chain: C: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: 2.00 angstrom resolution crystal structure of a catalytic2 subunit of an aspartate carbamoyltransferase (pyrb) from3 yersinia pestis co92

Phyre2

PDB 3tpf chain F

3D model

Region: 7 - 308
Aligned: 291
Modelled: 294
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: F: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of anabolic ornithine carbamoyltransferase from2 campylobacter jejuni subsp. jejuni nctc 11168

Phyre2

PDB 1zq2 chain A

3D model

Region: 8 - 305
Aligned: 293
Modelled: 297
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of n-acetyl-l-ornithine transcarbamylase2 complexed with cp

Phyre2

PDB 3grf chain A

3D model

Region: 6 - 306
Aligned: 281
Modelled: 299
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia

Phyre2

PDB 2p2g chain D

3D model

Region: 6 - 307
Aligned: 286
Modelled: 287
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form

Phyre2

PDB 3gd5 chain D

3D model

Region: 5 - 306
Aligned: 278
Modelled: 293
Confidence: 100.0%
Identity: 31%
PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus

Phyre2

PDB 3sds chain A

3D model

Region: 7 - 308
Aligned: 287
Modelled: 299
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial;
PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis

Phyre2

PDB 2ef0 chain A

3D model

Region: 6 - 305
Aligned: 282
Modelled: 296
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus

Phyre2

PDB 2at2 chain B

3D model

Region: 8 - 309
Aligned: 288
Modelled: 302
Confidence: 100.0%
Identity: 34%
PDB header:
PDB COMPND:

Phyre2
1

d1tuga1
2

c1ml4A_
3

c1pg5A_
4

c2rgwD_
5

c2w37A_
6

c2otcA_
7

c3updA_
8

c1vlvA_
9

c1ortD_
10

c1fvoB_
11

c1a1sA_
12

c3lxmC_
13

c3tpfF_
14

c1zq2A_
15

c3grfA_
16

c2p2gD_
17

c3gd5D_
18

c3sdsA_
19

c2ef0A_
20

c2at2B_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1tuga1



100.0 100 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
2c1ml4A_



100.0 52 PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi
3c1pg5A_



100.0 45 PDB header:transferase
Chain: A: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius
4c2rgwD_



100.0 48 PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase
5c2w37A_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic;
PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii
6c2otcA_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine
7c3updA_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus
8c1vlvA_



100.0 29 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution
9c1ortD_



100.0 28 PDB header:transferase
Chain: D: PDB Molecule:ornithine transcarbamoylase;
PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa
10c1fvoB_



100.0 24 PDB header:transferase
Chain: B: PDB Molecule:ornithine transcarbamylase;
PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate
11c1a1sA_



100.0 29 PDB header:transcarbamylase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus
12c3lxmC_



100.0 82 PDB header:transferase
Chain: C: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: 2.00 angstrom resolution crystal structure of a catalytic2 subunit of an aspartate carbamoyltransferase (pyrb) from3 yersinia pestis co92
13c3tpfF_



100.0 27 PDB header:transferase
Chain: F: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of anabolic ornithine carbamoyltransferase from2 campylobacter jejuni subsp. jejuni nctc 11168
14c1zq2A_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of n-acetyl-l-ornithine transcarbamylase2 complexed with cp
15c3grfA_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia
16c2p2gD_



100.0 33 PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form
17c3gd5D_



100.0 31 PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus
18c3sdsA_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial;
PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis
19c2ef0A_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus
20c2at2B_



100.0 34 PDB header:
PDB COMPND:
21c1js1Z_



not modelled 100.0 21 PDB header:transferase
Chain: Z: PDB Molecule:transcarbamylase;
PDBTitle: crystal structure of a new transcarbamylase from the2 anaerobic bacterium bacteroides fragilis at 2.0 a3 resolution
22c3d6nB_



not modelled 100.0 30 PDB header:hydrolase/transferase
Chain: B: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase
23c3q98A_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:transcarbamylase;
PDBTitle: structure of ygew encoded protein from e. coli
24d1ekxa1



not modelled 100.0 100 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
25d1ekxa2



not modelled 100.0 100 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
26d1ml4a1



not modelled 100.0 58 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
27d1vlva1



not modelled 100.0 34 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
28d1duvg1



not modelled 100.0 36 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
29d1pvva1



not modelled 100.0 35 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
30d1otha1



not modelled 100.0 28 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
31d1ml4a2



not modelled 100.0 48 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
32d1dxha1



not modelled 100.0 32 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
33d1pg5a1



not modelled 100.0 49 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
34d2at2a1



not modelled 100.0 44 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
35d1pg5a2



not modelled 100.0 40 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
36d1otha2



not modelled 100.0 19 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
37d1duvg2



not modelled 100.0 17 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
38d1dxha2



not modelled 100.0 24 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
39d1js1x1



not modelled 100.0 31 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
40d1pvva2



not modelled 100.0 24 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
41d1vlva2



not modelled 100.0 22 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
42d2at2a2



not modelled 100.0 25 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
43d2atca2



not modelled 100.0 81 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
44d1js1x2



not modelled 100.0 13 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
45c3d4oA_



not modelled 98.1 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
46c3gvpB_



not modelled 98.0 24 PDB header:hydrolase
Chain: B: PDB Molecule:adenosylhomocysteinase 3;
PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3
47c1d4fD_



not modelled 98.0 19 PDB header:hydrolase
Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase;
PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase
48c3oneA_



not modelled 97.9 17 PDB header:hydrolase/hydrolase substrate
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of lupinus luteus s-adenosyl-l-homocysteine2 hydrolase in complex with adenine
49c3n58D_



not modelled 97.9 18 PDB header:hydrolase
Chain: D: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form
50c3l07B_



not modelled 97.8 17 PDB header:oxidoreductase,hydrolase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis.
51c3dhyC_



not modelled 97.8 16 PDB header:hydrolase
Chain: C: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors
52c2rirA_



not modelled 97.8 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
53c1v8bA_



not modelled 97.8 19 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of a hydrolase
54c3d64A_



not modelled 97.7 16 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from2 burkholderia pseudomallei
55c2gcgB_



not modelled 97.7 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate reductase/hydroxypyruvate reductase;
PDBTitle: ternary crystal structure of human glyoxylate2 reductase/hydroxypyruvate reductase
56c3p2oB_



not modelled 97.5 14 PDB header:oxidoreductase, hydrolase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni
57c2j6iC_



not modelled 97.4 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:formate dehydrogenase;
PDBTitle: candida boidinii formate dehydrogenase (fdh) c-terminal2 mutant
58c1j4aA_



not modelled 97.3 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-lactate dehydrogenase;
PDBTitle: insights into domain closure, substrate specificity and2 catalysis of d-lactate dehydrogenase from lactobacillus3 bulgaricus
59d1gpja2



not modelled 97.3 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
60c3oetF_



not modelled 97.3 17 PDB header:oxidoreductase
Chain: F: PDB Molecule:erythronate-4-phosphate dehydrogenase;
PDBTitle: d-erythronate-4-phosphate dehydrogenase complexed with nad
61c3n7uD_



not modelled 97.3 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:formate dehydrogenase;
PDBTitle: nad-dependent formate dehydrogenase from higher-plant arabidopsis2 thaliana in complex with nad and azide
62c3bazA_



not modelled 97.3 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyphenylpyruvate reductase;
PDBTitle: structure of hydroxyphenylpyruvate reductase from coleus blumei in2 complex with nadp+
63c4a26B_



not modelled 97.3 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic;
PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase
64c2o4cB_



not modelled 97.2 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:erythronate-4-phosphate dehydrogenase;
PDBTitle: crystal structure of d-erythronate-4-phosphate dehydrogenase complexed2 with nad
65c1xdwA_



not modelled 97.2 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad+-dependent (r)-2-hydroxyglutarate
PDBTitle: nad+-dependent (r)-2-hydroxyglutarate dehydrogenase from2 acidaminococcus fermentans
66c2dbqA_



not modelled 97.2 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:glyoxylate reductase;
PDBTitle: crystal structure of glyoxylate reductase (ph0597) from pyrococcus2 horikoshii ot3, complexed with nadp (i41)
67c1gpjA_



not modelled 97.1 14 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri
68c1ybaC_



not modelled 97.1 16 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: the active form of phosphoglycerate dehydrogenase
69c2omeA_



not modelled 97.0 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:c-terminal-binding protein 2;
PDBTitle: crystal structure of human ctbp2 dehydrogenase complexed with nad(h)
70c1gdhA_



not modelled 97.0 11 PDB header:oxidoreductase(choh (d)-nad(p)+ (a))
Chain: A: PDB Molecule:d-glycerate dehydrogenase;
PDBTitle: crystal structure of a nad-dependent d-glycerate2 dehydrogenase at 2.4 angstroms resolution
71c3p2yA_



not modelled 97.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:alanine dehydrogenase/pyridine nucleotide transhydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase/pyridine nucleotide2 transhydrogenase from mycobacterium smegmatis
72d1mx3a1



not modelled 97.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
73d1li4a1



not modelled 97.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
74d2naca1



not modelled 96.9 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
75c1b0aA_



not modelled 96.9 14 PDB header:oxidoreductase,hydrolase
Chain: A: PDB Molecule:protein (fold bifunctional protein);
PDBTitle: 5,10, methylene-tetrahydropholate2 dehydrogenase/cyclohydrolase from e coli.
76c3p2oA_



not modelled 96.9 14 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni
77c2cukC_



not modelled 96.9 24 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerate dehydrogenase/glyoxylate reductase;
PDBTitle: crystal structure of tt0316 protein from thermus thermophilus hb8
78c3kboB_



not modelled 96.9 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate/hydroxypyruvate reductase a;
PDBTitle: 2.14 angstrom crystal structure of putative oxidoreductase (ycdw) from2 salmonella typhimurium in complex with nadp
79c1l7eC_



not modelled 96.8 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:nicotinamide nucleotide transhydrogenase,
PDBTitle: crystal structure of r. rubrum transhydrogenase domain i2 with bound nadh
80c2nacA_



not modelled 96.8 18 PDB header:oxidoreductase(aldehyde(d),nad+(a))
Chain: A: PDB Molecule:nad-dependent formate dehydrogenase;
PDBTitle: high resolution structures of holo and apo formate dehydrogenase
81d1gdha1



not modelled 96.8 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
82c3hg7A_



not modelled 96.8 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-isomer specific 2-hydroxyacid dehydrogenase family
PDBTitle: crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase2 family protein from aeromonas salmonicida subsp. salmonicida a449
83d1l7da1



not modelled 96.8 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
84c2bruB_



not modelled 96.7 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:nad(p) transhydrogenase subunit alpha;
PDBTitle: complex of the domain i and domain iii of escherichia coli2 transhydrogenase
85d1a4ia1



not modelled 96.7 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
86c1wwkA_



not modelled 96.7 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from pyrococcus2 horikoshii ot3
87c2g76A_



not modelled 96.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase
88d1pjca1



not modelled 96.6 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
89c3gg9C_



not modelled 96.6 13 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase oxidoreductase protein;
PDBTitle: crystal structure of putative d-3-phosphoglycerate dehydrogenase2 oxidoreductase from ralstonia solanacearum
90c3evtA_



not modelled 96.6 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from2 lactobacillus plantarum
91c1pjcA_



not modelled 96.5 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (l-alanine dehydrogenase);
PDBTitle: l-alanine dehydrogenase complexed with nad
92d1sc6a1



not modelled 96.5 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
93c3k5pA_



not modelled 96.4 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of amino acid-binding act: d-isomer specific 2-2 hydroxyacid dehydrogenase catalytic domain from brucella melitensis
94c2pi1C_



not modelled 96.4 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-lactate dehydrogenase;
PDBTitle: crystal structure of d-lactate dehydrogenase from aquifex2 aeolicus complexed with nad and lactic acid
95c3dfzB_



not modelled 96.4 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:precorrin-2 dehydrogenase;
PDBTitle: sirc, precorrin-2 dehydrogenase
96d1qp8a1



not modelled 96.4 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
97c3gvxA_



not modelled 96.4 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerate dehydrogenase related protein;
PDBTitle: crystal structure of glycerate dehydrogenase related2 protein from thermoplasma acidophilum
98c2eklA_



not modelled 96.3 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: structure of st1218 protein from sulfolobus tokodaii
99d2dlda1



not modelled 96.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
100c1dxyA_



not modelled 96.3 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-2-hydroxyisocaproate dehydrogenase;
PDBTitle: structure of d-2-hydroxyisocaproate dehydrogenase
101c2eezG_



not modelled 96.2 14 PDB header:oxidoreductase
Chain: G: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase from themus thermophilus
102d1pjqa1



not modelled 96.1 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
103c1ygyA_



not modelled 96.1 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of d-3-phosphoglycerate dehydrogenase from2 mycobacterium tuberculosis
104c1qp8A_



not modelled 96.1 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:formate dehydrogenase;
PDBTitle: crystal structure of a putative formate dehydrogenase from2 pyrobaculum aerophilum
105c4a5oB_



not modelled 96.0 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of pseudomonas aeruginosa n5, n10-2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold)
106c2w2kB_



not modelled 96.0 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-mandelate dehydrogenase;
PDBTitle: crystal structure of the apo forms of rhodotorula graminis2 d-mandelate dehydrogenase at 1.8a.
107d1j4aa1



not modelled 95.9 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
108d1ygya1



not modelled 95.9 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
109d1dxya1



not modelled 95.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
110d1np3a2



not modelled 95.8 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
111c3d1lB_



not modelled 95.8 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
112c3nglA_



not modelled 95.8 16 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of bifunctional 5,10-methylenetetrahydrofolate2 dehydrogenase / cyclohydrolase from thermoplasma acidophilum
113d1b0aa1



not modelled 95.8 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
114c2c2xB_



not modelled 95.7 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase-
PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis
115d1fmta2



not modelled 95.6 21 Fold:Formyltransferase
Superfamily:Formyltransferase
Family:Formyltransferase
116c1a4iB_



not modelled 95.5 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase /
PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase
117c1vjtA_



not modelled 95.3 17 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-glucosidase;
PDBTitle: crystal structure of alpha-glucosidase (tm0752) from thermotoga2 maritima at 2.50 a resolution
118c3cumA_



not modelled 95.3 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
119c3gg2B_



not modelled 95.3 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
120c2d0iC_



not modelled 95.2 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure ph0520 protein from pyrococcus horikoshii ot3

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0