Phyre 2 Results for Q9JMS3

Email	l.a.kelley@imperial.ac.uk
Description	Q9JMS3
Date	Wed Jan 25 15:21:16 GMT 2012
Unique Job ID	87afecb42b303d3e

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c3sljA_

Top template information

PDB header:protein transport
Chain: A: PDB Molecule:serine protease espp;
PDBTitle: pre-cleavage structure of the autotransporter espp - n1023a mutant

Confidence and coverage

Confidence:

100.0%

Coverage:

21%

291 residues ( 21% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

866 residues ( 63%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M N C Q R Y F C F V N G I V E I R T A P E E Y Q N K P V L V G S Q S D G L L I I D N H A D I E D G I F S T L H I G N G Y

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ?
?
? ?
?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence N G A V D V I N G A A L H M D N R S G S A P L I V G A F G N D I A G K L N I S G R N S I V S Y R D T P S S S G H N E S I

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence Y V G F G P G A T G W I N I F N G G V F E V L N S T N I Y V G S D T P G G G D G S I V I D G S N S K M T A D F S E A Y V

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?
? ?
? ?
?
? ? ? ? ? ? ?
? ?
?
? ? ? ?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence G L Y G N G D I S L K N G G Q L S A S N L Y I G G N G R A I V N I S G T D S R L I A N M I T I S G S S G A P G I Y I A D

Secondary structure

SS confidence

Disorder
?
?
? ?
? ? ? ?
? ? ? ? ?
? ? ? ? ? ? ? ? ? ?
? ?
? ? ? ?
?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence Q G I L N V D N Y I N I T T A N D T K G K L F I N S D M P G T I E S K G I L F G V G K A E L I F K H N S D N Y A F S S P

Secondary structure

SS confidence

Disorder ? ?
? ? ? ?
? ?
? ?
? ? ? ? ? ?
? ? ? ?
? ? ?
?
?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence L I S K N T G N G I I N A E S G E T H L T G D N T D Y S G L L N I L P T A S I D I S S Q K N I G K S V I V N N G V L Q I

Secondary structure

SS confidence

Disorder ? ? ? ? ? ?
?
?
? ?
?
? ?
? ? ? ? ? ? ? ? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence T S Q D D W T F N N N M T G N G Y L N V H T G G H N F A F Q N S T N T Q E F T G T L A L S D T L F D L S D D N T T A L T

Secondary structure

SS confidence

Disorder
? ? ? ?
? ? ?
? ?
?
? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence S A L V L A G V G S V I T A G T G T Q V I N G F S F D G G A V N F G A V T Q G A Q Q T E S Q I Q V T D N L Y I N G N G A

Secondary structure

SS confidence

Disorder ? ?
? ? ? ? ?
? ? ?
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence V R V S T P T D V N G I P Q V I N S S L S L L E Q D D S N A T I K L V D A S S A V V K G N G G N L Q L Q D A S G Q V I S

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ?
? ? ? ? ?
? ?
? ?
?
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence S G K Q R N I V Q Q G K N V A K G V Y D Y R L T S G P H N D G L Y I G Y A L T Q L D L L A S G V D A L V L D A A G T T G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ?
? ? ?
?
? ? ? ? ? ?
?
?
?
? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence N A A D M S A R I T G A G D L A F N S Q K G E T V S L S N Q D N D Y T G V T A I R G G N V L M N S N S V L G Q T S E I R

Secondary structure

SS confidence

Disorder ? ? ?
?
? ? ? ? ? ?
?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence L A T D T R L D M N G H S Q T V G K L N G A A G S V L N I N G G N L T L T D D G V S A G T L T G G G F L N I S G G V L D

Secondary structure

SS confidence

Disorder
? ? ?
? ? ? ? ? ?
? ? ?
?
? ?
? ? ?
?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence I T G G N H T F A V S T I I A K D A T V R M N D V S G L G T G N I S N A G T L S L T H A S G L L S N N L S G S G T V S L

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ?
?
? ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence I N S D T Q I S G N N S N Y S G L F V V D T S S Q L T A T G A Q N L G I A S V S N R G I L Q L N N T T D W Q L I N N V T

Secondary structure

SS confidence

Disorder ?
?
? ? ? ? ?
? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence G T G N V R K T G S G S L T V R S N A A W S G Q T D I D D G S L I L G Q S D A P V M L A S S L V N I A K N G K L T G F G

Secondary structure

SS confidence

Disorder
?
?
? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence G V V G N V T N S G S L D L R S A A P G N I L T I G G N Y T G N N G T L L I N T V L D D S S S A T D K L V I K G D A S G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence K T R V A V T N V G G S G A N T L N S I E V I H V D G N A A N A E F I Q A G R I A A G A Y D Y T L G R G P G S N Y G N W

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ?
?
?
? ? ? ?
?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence Y L S S S K N T P E P R P D P E P T P E G H D N N L R P E A S S Y T A N I A A A N T M F V T R L H E R L G Q T Q Y V D A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence I T G E P K A T S M W M R H E G G H N R W R D G S G Q L K T Q S N R Y V I Q L G G D I A Q W D W G G T N R W H L G V M A

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190 . . . . . . . . . 1200

Sequence G Y G N N H S S T G A V R T G Y H S K G S V N G Y S T G L Y A T W Y A D D E T H N G A Y L D T W A Q Y G W F D N H V K G

Secondary structure

SS confidence

Disorder
? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ?
?

Disorder confidence

. . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence D G L P G E S W K S K G L T A S L E T G Y A W K I G E F S S N Y G N L N E W Y V Q P Q A Q L V W M G V K A D E L Y E S N

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
? ? ? ? ? ?
? ?
?
? ?

Disorder confidence

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320

Sequence G T L I E S T G D G N V H T R L G V K T W I K R L N K M D D G K S R E F S P F V E V N W L H N T R D F G V R M N G E P V

Secondary structure

SS confidence

Disorder ? ?
? ? ? ?
? ? ? ?
? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 1330 . . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 .

Sequence Y Q D G T R N I G E V K T G V E G Q I N P H L N L W G N V R V Q V G D K G Y N D T S A M L G V K Y T F

Secondary structure

SS confidence

Disorder ? ? ?
?
?
? ? ? ? ? ? ? ? ?
?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 3slj chain A

Region: 1044 - 1371
Aligned: 291
Modelled: 328
Confidence: 100.0%
Identity: 20%
PDB header:protein transport
Chain: A: PDB Molecule:serine protease espp;
PDBTitle: pre-cleavage structure of the autotransporter espp - n1023a mutant

Phyre2

PDB 3aeh chain B

Region: 1046 - 1371
Aligned: 271
Modelled: 314
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: B: PDB Molecule:hemoglobin-binding protease hbp autotransporter;
PDBTitle: integral membrane domain of autotransporter hbp

Phyre2

PDB 3qq2 chain C

Region: 1086 - 1371
Aligned: 245
Modelled: 281
Confidence: 100.0%
Identity: 24%
PDB header:membrane protein/protein transport
Chain: C: PDB Molecule:brka autotransporter;
PDBTitle: crystal structure of the beta domain of the bordetella autotransporter2 brka

Phyre2

PDB 3kvn chain A

Region: 1050 - 1371
Aligned: 292
Modelled: 322
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:esterase esta;
PDBTitle: crystal structure of the full-length autotransporter esta from2 pseudomonas aeruginosa

Phyre2

PDB 1uyn chain X

Region: 1051 - 1371
Aligned: 268
Modelled: 321
Confidence: 100.0%
Identity: 18%
Fold: Transmembrane beta-barrels
Superfamily: Autotransporter
Family: Autotransporter

Phyre2

PDB 2qom chain B

Region: 1068 - 1371
Aligned: 261
Modelled: 302
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: B: PDB Molecule:serine protease espp;
PDBTitle: the crystal structure of the e.coli espp autotransporter beta-domain.

Phyre2

PDB 3ml3 chain A

Region: 875 - 1027
Aligned: 152
Modelled: 153
Confidence: 99.6%
Identity: 36%
PDB header:protein transport
Chain: A: PDB Molecule:outer membrane protein icsa autotransporter;
PDBTitle: crystal structure of the icsa autochaperone region

Phyre2

PDB 1dab chain A

Region: 471 - 1029
Aligned: 535
Modelled: 545
Confidence: 99.6%
Identity: 14%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Virulence factor P.69 pertactin

Phyre2

PDB 1g90 chain A

Region: 1177 - 1371
Aligned: 163
Modelled: 195
Confidence: 99.1%
Identity: 16%
Fold: Transmembrane beta-barrels
Superfamily: OMPA-like
Family: Outer membrane protein

Phyre2

PDB 1p4t chain A

Region: 1178 - 1371
Aligned: 150
Modelled: 194
Confidence: 99.1%
Identity: 21%
Fold: Transmembrane beta-barrels
Superfamily: OMPA-like
Family: Outer membrane protein

Phyre2

PDB 3nb3 chain C

Region: 1177 - 1371
Aligned: 136
Modelled: 169
Confidence: 98.9%
Identity: 21%
PDB header:virus
Chain: C: PDB Molecule:outer membrane protein a;
PDBTitle: the host outer membrane proteins ompa and ompc are packed at specific2 sites in the shigella phage sf6 virion as structural components

Phyre2

PDB 2k0l chain A

Region: 1177 - 1371
Aligned: 168
Modelled: 177
Confidence: 98.9%
Identity: 14%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles.

Phyre2

PDB 1qjp chain A

Region: 1180 - 1371
Aligned: 133
Modelled: 164
Confidence: 98.9%
Identity: 20%
Fold: Transmembrane beta-barrels
Superfamily: OMPA-like
Family: Outer membrane protein

Phyre2

PDB 2x27 chain X

Region: 1177 - 1371
Aligned: 174
Modelled: 194
Confidence: 98.8%
Identity: 15%
PDB header:membrane protein
Chain: X: PDB Molecule:outer membrane protein oprg;
PDBTitle: crystal structure of the outer membrane protein oprg from2 pseudomonas aeruginosa

Phyre2

PDB 2jmm chain A

Region: 1180 - 1371
Aligned: 145
Modelled: 168
Confidence: 98.8%
Identity: 17%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr solution structure of a minimal transmembrane beta-2 barrel platform protein

Phyre2

PDB 3qra chain A

Region: 1187 - 1371
Aligned: 148
Modelled: 185
Confidence: 98.8%
Identity: 16%
PDB header:cell invasion
Chain: A: PDB Molecule:attachment invasion locus protein;
PDBTitle: the crystal structure of ail, the attachment invasion locus protein of2 yersinia pestis

Phyre2

PDB 2f1t chain B

Region: 1180 - 1371
Aligned: 161
Modelled: 181
Confidence: 98.7%
Identity: 12%
PDB header:membrane protein
Chain: B: PDB Molecule:outer membrane protein w;
PDBTitle: outer membrane protein ompw

Phyre2

PDB 3h09 chain B

Region: 399 - 1025
Aligned: 617
Modelled: 627
Confidence: 98.7%
Identity: 11%
PDB header:hydrolase
Chain: B: PDB Molecule:immunoglobulin a1 protease;
PDBTitle: the structure of haemophilus influenzae iga1 protease

Phyre2

PDB 1qj8 chain A

Region: 1211 - 1371
Aligned: 131
Modelled: 149
Confidence: 98.4%
Identity: 9%
Fold: Transmembrane beta-barrels
Superfamily: OMPA-like
Family: Outer membrane protein

Phyre2

PDB 3a2r chain X

Region: 1122 - 1371
Aligned: 207
Modelled: 236
Confidence: 97.8%
Identity: 16%
PDB header:membrane protein
Chain: X: PDB Molecule:outer membrane protein ii;
PDBTitle: crystal structure of outer membrane protein porb from neisseria2 meningitidis