Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	K	L	K	L	H	G	F	N	N	L	T	K	S	L	S	F	C	I	Y	D	I	C	Y	A	K	T	A	E	E	R	D	G	Y	I	A	Y	I	D	E	L	Y	N	A	N	R	L	T	E	I	L	S	E	T	C	S	I	I	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	N	I	L	N	I	A	R	Q	D	Y	E	P	Q	G	A	S	V	T	I	L	V	S	E	E	P	V	D	P	K	L	I	D	K	T	E	H	P	G	P	L	P	E	T	V	V	A	H	L	D	K	S	H	I	C	V	H	T	Y	P
Secondary structure
SS confidence
Disorder																									?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	S	H	P	E	G	G	L	C	T	F	R	A	D	I	E	V	S	T	C	G	V	I	S	P	L	K	A	L	N	Y	L	I	H	Q	L	E	S	D	I	V	T	I	D	Y	R	V	R	G	F	T	R	D	I	N	G	M	K	H	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	D	H	E	I	N	S	I	Q	N	F	M	S	D	D	M	K	A	L	Y	D	M	V	D	V	N	V	Y	Q	E	N	I	F	H	T	K	M	L	L	K	E	F	D	L	K	H	Y	M	F	H	T	K	P	E	D	L	T	D	S	E
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.
Sequence		R	Q	E	I	T	A	A	L	W	K	E	M	R	E	I	Y	Y	G	R	N	M	P	A	V
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2iii chain A Region: 40 - 177 Aligned: 102 Modelled: 111 Confidence: 100.0% Identity: 28% PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase proenzyme; PDBTitle: crystal structure of the adenosylmethionine decarboxylase (aq_254)2 from aquifex aeolicus vf5 Phyre2 PDB 1vr7 chain A domain 1 Region: 40 - 174 Aligned: 100 Modelled: 108 Confidence: 100.0% Identity: 35% Fold: S-adenosylmethionine decarboxylase Superfamily: S-adenosylmethionine decarboxylase Family: Bacterial S-adenosylmethionine decarboxylase Phyre2 PDB 1vr7 chain A Region: 40 - 174 Aligned: 100 Modelled: 108 Confidence: 100.0% Identity: 35% PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase proenzyme; PDBTitle: crystal structure of s-adenosylmethionine decarboxylase proenzyme2 (tm0655) from thermotoga maritima at 1.2 a resolution Phyre2 PDB 3iwd chain C Region: 113 - 174 Aligned: 54 Modelled: 62 Confidence: 99.7% Identity: 39% PDB header:lyase Chain: C: PDB Molecule:s-adenosylmethionine decarboxylase; PDBTitle: t. maritima adometdc complex with 5'-deoxy-5'-dimethyl2 thioadenosine Phyre2 PDB 3iwc chain D Region: 44 - 84 Aligned: 41 Modelled: 41 Confidence: 98.9% Identity: 22% PDB header:lyase Chain: D: PDB Molecule:s-adenosylmethionine decarboxylase; PDBTitle: t. maritima adometdc complex with s-adenosylmethionine2 methyl ester Phyre2 PDB 1mhm chain A Region: 66 - 163 Aligned: 63 Modelled: 71 Confidence: 81.8% Identity: 24% PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase; PDBTitle: crystal structure of s-adenosylmethionine decarboxylase2 from potato Phyre2 PDB 3ep3 chain A Region: 66 - 172 Aligned: 72 Modelled: 80 Confidence: 79.9% Identity: 26% PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase alpha chain; PDBTitle: human adometdc d174n mutant with no putrescine bound Phyre2 PDB 3som chain O Region: 104 - 135 Aligned: 27 Modelled: 29 Confidence: 58.8% Identity: 30% PDB header:oxidoreductase Chain: O: PDB Molecule:methylmalonic aciduria and homocystinuria type c protein; PDBTitle: crystal structure of human mmachc Phyre2 PDB 1msv chain B Region: 49 - 172 Aligned: 78 Modelled: 97 Confidence: 54.9% Identity: 26% PDB header:lyase Chain: B: PDB Molecule:s-adenosylmethionine decarboxylase proenzyme; PDBTitle: the s68a s-adenosylmethionine decarboxylase proenzyme2 processing mutant. Phyre2 PDB 1jl0 chain A Region: 49 - 172 Aligned: 78 Modelled: 97 Confidence: 50.2% Identity: 28% Fold: S-adenosylmethionine decarboxylase Superfamily: S-adenosylmethionine decarboxylase Family: S-adenosylmethionine decarboxylase Phyre2 PDB 2lb0 chain A Region: 172 - 183 Aligned: 12 Modelled: 12 Confidence: 41.7% Identity: 17% PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a di-2 phosphorylated human smad1 derived peptide Phyre2 PDB 1u58 chain A domain 1 Region: 60 - 140 Aligned: 67 Modelled: 81 Confidence: 39.9% Identity: 19% Fold: Immunoglobulin-like beta-sandwich Superfamily: Immunoglobulin Family: C1 set domains (antibody constant domain-like) Phyre2 PDB 2laz chain A Region: 172 - 183 Aligned: 12 Modelled: 12 Confidence: 39.4% Identity: 17% PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide Phyre2 PDB 3c6k chain C Region: 115 - 141 Aligned: 19 Modelled: 27 Confidence: 34.5% Identity: 32% PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine Phyre2 PDB 1d9k chain D Region: 60 - 140 Aligned: 63 Modelled: 81 Confidence: 32.8% Identity: 21% PDB header:immune system Chain: D: PDB Molecule:mhc i-ak b chain (beta chain); PDBTitle: crystal structure of complex between d10 tcr and pmhc i-ak/ca Phyre2 PDB 3k1h chain A Region: 13 - 59 Aligned: 43 Modelled: 47 Confidence: 31.8% Identity: 19% PDB header:chaperone Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of hp1076 from h.pylori Phyre2 PDB 2l4j chain A Region: 172 - 183 Aligned: 12 Modelled: 12 Confidence: 31.7% Identity: 25% PDB header:transcription Chain: A: PDB Molecule:yes-associated protein 2 (yap2); PDBTitle: yap ww2 Phyre2 PDB 1mh5 chain H domain 2 Region: 64 - 140 Aligned: 49 Modelled: 50 Confidence: 29.2% Identity: 22% Fold: Immunoglobulin-like beta-sandwich Superfamily: Immunoglobulin Family: C1 set domains (antibody constant domain-like) Phyre2 PDB 2f21 chain A domain 1 Region: 172 - 183 Aligned: 12 Modelled: 12 Confidence: 26.9% Identity: 17% Fold: WW domain-like Superfamily: WW domain Family: WW domain Phyre2 PDB 2kl5 chain A Region: 166 - 192 Aligned: 26 Modelled: 27 Confidence: 26.3% Identity: 23% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein yutd; PDBTitle: solution nmr structure of protein yutd from b.subtilis, northeast2 structural genomics consortium target sr232 Phyre2 1 c2iiiA_ 2 d1vr7a1 3 c1vr7A_ 4 c3iwdC_ 5 c3iwcD_ 6 c1mhmA_ 7 c3ep3A_ 8 c3somO_ 9 c1msvB_ 10 d1jl0a_ 11 c2lb0A_ 12 d1u58a1 13 c2lazA_ 14 c3c6kC_ 15 c1d9kD_ 16 c3k1hA_ 17 c2l4jA_ 18 d1mh5h2 19 d2f21a1 20 c2kl5A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2iiiA_ 100.0 28 PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase proenzyme; PDBTitle: crystal structure of the adenosylmethionine decarboxylase (aq_254)2 from aquifex aeolicus vf5 2 d1vr7a1 100.0 35 Fold:S-adenosylmethionine decarboxylase Superfamily:S-adenosylmethionine decarboxylase Family:Bacterial S-adenosylmethionine decarboxylase 3 c1vr7A_ 100.0 35 PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase proenzyme; PDBTitle: crystal structure of s-adenosylmethionine decarboxylase proenzyme2 (tm0655) from thermotoga maritima at 1.2 a resolution 4 c3iwdC_ 99.7 39 PDB header:lyase Chain: C: PDB Molecule:s-adenosylmethionine decarboxylase; PDBTitle: t. maritima adometdc complex with 5'-deoxy-5'-dimethyl2 thioadenosine 5 c3iwcD_ 98.9 22 PDB header:lyase Chain: D: PDB Molecule:s-adenosylmethionine decarboxylase; PDBTitle: t. maritima adometdc complex with s-adenosylmethionine2 methyl ester 6 c1mhmA_ 81.8 24 PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase; PDBTitle: crystal structure of s-adenosylmethionine decarboxylase2 from potato 7 c3ep3A_ 79.9 26 PDB header:lyase Chain: A: PDB Molecule:s-adenosylmethionine decarboxylase alpha chain; PDBTitle: human adometdc d174n mutant with no putrescine bound 8 c3somO_ 58.8 30 PDB header:oxidoreductase Chain: O: PDB Molecule:methylmalonic aciduria and homocystinuria type c protein; PDBTitle: crystal structure of human mmachc 9 c1msvB_ 54.9 26 PDB header:lyase Chain: B: PDB Molecule:s-adenosylmethionine decarboxylase proenzyme; PDBTitle: the s68a s-adenosylmethionine decarboxylase proenzyme2 processing mutant. 10 d1jl0a_ 50.2 28 Fold:S-adenosylmethionine decarboxylase Superfamily:S-adenosylmethionine decarboxylase Family:S-adenosylmethionine decarboxylase 11 c2lb0A_ 41.7 17 PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a di-2 phosphorylated human smad1 derived peptide 12 d1u58a1 39.9 19 Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:C1 set domains (antibody constant domain-like) 13 c2lazA_ 39.4 17 PDB header:signaling protein/transcription Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf1; PDBTitle: structure of the first ww domain of human smurf1 in complex with a2 mono-phosphorylated human smad1 derived peptide 14 c3c6kC_ 34.5 32 PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine 15 c1d9kD_ 32.8 21 PDB header:immune system Chain: D: PDB Molecule:mhc i-ak b chain (beta chain); PDBTitle: crystal structure of complex between d10 tcr and pmhc i-ak/ca 16 c3k1hA_ 31.8 19 PDB header:chaperone Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of hp1076 from h.pylori 17 c2l4jA_ 31.7 25 PDB header:transcription Chain: A: PDB Molecule:yes-associated protein 2 (yap2); PDBTitle: yap ww2 18 d1mh5h2 29.2 22 Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:C1 set domains (antibody constant domain-like) 19 d2f21a1 26.9 17 Fold:WW domain-like Superfamily:WW domain Family:WW domain 20 c2kl5A_ 26.3 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein yutd; PDBTitle: solution nmr structure of protein yutd from b.subtilis, northeast2 structural genomics consortium target sr232 21 c1iaoB_ not modelled 26.2 21 PDB header:mhc ii Chain: B: PDB Molecule:mhc class ii i-ad; PDBTitle: class ii mhc i-ad in complex with ovalbumin peptide 323-339 22 c1iebD_ not modelled 23.8 24 PDB header:histocompatibility antigen Chain: D: PDB Molecule:mhc class ii i-ek; PDBTitle: histocompatibility antigen 23 c2q6wD_ not modelled 23.3 19 PDB header:immune system Chain: D: PDB Molecule:hla class ii histocompatibility antigen, dr PDBTitle: the structure of hla-dra, drb3*0101 (dr52a) with bound2 platelet integrin peptide associated with fetal and3 neonatal alloimmune thrombocytopenia 24 c2kq0A_ not modelled 22.3 50 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: human nedd4 3rd ww domain complex with ebola zaire virus matrix2 protein vp40 derived peptide ilptappeymea 25 c1pqzA_ not modelled 21.6 19 PDB header:viral protein/immune system Chain: A: PDB Molecule:mcmv m144; PDBTitle: murine cytomegalovirus immunomodulatory protein m144 26 c2p24A_ not modelled 20.0 16 PDB header:immune system Chain: A: PDB Molecule:h-2 class ii histocompatibility antigen, a-u alpha chain; PDBTitle: i-au/mbp125-135 27 c3lqzA_ not modelled 18.7 22 PDB header:immune system Chain: A: PDB Molecule:hla class ii histocompatibility antigen, dp alpha 1 chain; PDBTitle: crystal structure of hla-dp2 28 d2jmfa1 not modelled 17.9 31 Fold:WW domain-like Superfamily:WW domain Family:WW domain 29 c2jmfA_ not modelled 17.6 33 PDB header:ligase/signaling protein Chain: A: PDB Molecule:e3 ubiquitin-protein ligase suppressor of deltex; PDBTitle: solution structure of the su(dx) ww4- notch py peptide2 complex 30 c2xm5A_ not modelled 17.1 29 PDB header:transferase Chain: A: PDB Molecule:cloq; PDBTitle: structural and mechanistic analysis of the magnesium-2 independent aromatic prenyltransferase cloq from the3 clorobiocin biosynthetic pathway 31 c2p24B_ not modelled 16.7 21 PDB header:immune system Chain: B: PDB Molecule:h-2 class ii histocompatibility antigen, a-u beta chain; PDBTitle: i-au/mbp125-135 32 c1ik9C_ not modelled 16.2 33 PDB header:gene regulation/ligase Chain: C: PDB Molecule:dna ligase iv; PDBTitle: crystal structure of a xrcc4-dna ligase iv complex 33 c1wr4A_ not modelled 16.0 23 PDB header:ligase Chain: A: PDB Molecule:ubiquitin-protein ligase nedd4-2; PDBTitle: solution structure of the second ww domain of nedd4-2 34 c1ymzA_ not modelled 15.8 15 PDB header:unknown function Chain: A: PDB Molecule:cc45; PDBTitle: cc45, an artificial ww domain designed using statistical2 coupling analysis 35 c1zhbJ_ not modelled 15.8 17 PDB header:immune system Chain: J: PDB Molecule:h-2 class i histocompatibility antigen, d-b PDBTitle: crystal structure of the murine class i major2 histocompatibility complex of h-2db, b2-microglobulin, and3 a 9-residue peptide derived from rat dopamine beta-4 monooxigenase 36 c2ez5W_ not modelled 15.5 40 PDB header:signalling protein,ligase Chain: W: PDB Molecule:e3 ubiquitin-protein ligase nedd4; PDBTitle: solution structure of the dnedd4 ww3* domain- comm lpsy2 peptide complex 37 c2ysbA_ not modelled 15.0 38 PDB header:protein binding Chain: A: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the first ww domain from the mouse2 salvador homolog 1 protein (sav1) 38 c1e0mA_ not modelled 15.0 23 PDB header:de novo protein Chain: A: PDB Molecule:wwprototype; PDBTitle: prototype ww domain 39 d1i5hw_ not modelled 14.8 27 Fold:WW domain-like Superfamily:WW domain Family:WW domain 40 c2zajA_ not modelled 14.7 25 PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the short-isoform of the second ww2 domain from the human membrane-associated guanylate kinase,3 ww and pdz domain-containing protein 1 (magi-1) 41 c2yshA_ not modelled 14.6 8 PDB header:protein binding Chain: A: PDB Molecule:growth-arrest-specific protein 7; PDBTitle: solution structure of the ww domain from the human growth-2 arrest-specific protein 7, gas-7 42 c1yiuA_ not modelled 14.6 42 PDB header:ligase Chain: A: PDB Molecule:itchy e3 ubiquitin protein ligase; PDBTitle: itch e3 ubiquitin ligase ww3 domain 43 c1v1cA_ not modelled 14.0 29 PDB header:sh3-domain Chain: A: PDB Molecule:obscurin; PDBTitle: solution structure of the sh3 domain of obscurin 44 d1tk7a2 not modelled 14.0 33 Fold:WW domain-like Superfamily:WW domain Family:WW domain 45 c1wmvA_ not modelled 13.0 46 PDB header:oxidoreductase, apoptosis Chain: A: PDB Molecule:ww domain containing oxidoreductase; PDBTitle: solution structure of the second ww domain of wwox 46 c3l4hA_ not modelled 13.0 38 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase hecw1; PDBTitle: helical box domain and second ww domain of the human e3 ubiquitin-2 protein ligase hecw1 47 c2clvA_ not modelled 12.9 16 PDB header:immune system Chain: A: PDB Molecule:h-2 class i histocompatibility antigen, k-b PDBTitle: mhc class i natural mutant h-2kbm8 heavy chain complexed2 with beta-2 microglobulin and pbm8 peptide 48 d1k9ra_ not modelled 12.9 25 Fold:WW domain-like Superfamily:WW domain Family:WW domain 49 c2ysgA_ not modelled 12.7 42 PDB header:protein binding Chain: A: PDB Molecule:syntaxin-binding protein 4; PDBTitle: solution structure of the ww domain from the human syntaxin-2 binding protein 4 50 c2dmvA_ not modelled 12.1 31 PDB header:ligase Chain: A: PDB Molecule:itchy homolog e3 ubiquitin protein ligase; PDBTitle: solution structure of the second ww domain of itchy homolog2 e3 ubiquitin protein ligase (itch) 51 c2djyA_ not modelled 11.7 27 PDB header:ligase/signaling protein Chain: A: PDB Molecule:smad ubiquitination regulatory factor 2; PDBTitle: solution structure of smurf2 ww3 domain-smad7 py peptide2 complex 52 c2lawA_ not modelled 11.6 23 PDB header:signaling protein/transcription Chain: A: PDB Molecule:yorkie homolog; PDBTitle: structure of the second ww domain from human yap in complex with a2 human smad1 derived peptide 53 c3zr8X_ not modelled 10.9 16 PDB header:protein binding Chain: X: PDB Molecule:avr3a11; PDBTitle: crystal structure of rxlr effector avr3a11 from phytophthora capsici 54 d2nnab1 not modelled 10.9 20 Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:C1 set domains (antibody constant domain-like) 55 c1wr7A_ not modelled 10.8 43 PDB header:ligase Chain: A: PDB Molecule:nedd4-2; PDBTitle: solution structure of the third ww domain of nedd4-2 56 d1tk7a1 not modelled 10.7 17 Fold:WW domain-like Superfamily:WW domain Family:WW domain 57 c2yscA_ not modelled 10.6 9 PDB header:protein binding Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family PDBTitle: solution structure of the ww domain from the human amyloid2 beta a4 precursor protein-binding family b member 3, apbb3 58 c2dwvB_ not modelled 10.5 17 PDB header:protein binding Chain: B: PDB Molecule:salvador homolog 1 protein; PDBTitle: solution structure of the second ww domain from mouse2 salvador homolog 1 protein (mww45) 59 c3zv0A_ not modelled 10.5 19 PDB header:cell cycle Chain: A: PDB Molecule:protein shq1; PDBTitle: structure of the shq1p-cbf5p complex 60 c2yf6A_ not modelled 10.2 19 PDB header:immune system Chain: A: PDB Molecule:major histocompatibility complex class i glycoprotein PDBTitle: complex of a b21 chicken mhc class i molecule and a 10mer2 chicken peptide 61 c3bzeA_ not modelled 10.2 17 PDB header:immune system Chain: A: PDB Molecule:hla class i histocompatibility antigen, alpha chain e; PDBTitle: the human non-classical major histocompatibility complex molecule hla-2 e 62 d1ynja1 not modelled 10.1 37 Fold:DCoH-like Superfamily:RBP11-like subunits of RNA polymerase Family:RNA polymerase alpha subunit dimerisation domain 63 c2ysfA_ not modelled 9.8 29 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: solution structure of the fourth ww domain from the human2 e3 ubiquitin-protein ligase itchy homolog, itch 64 c1zt7C_ not modelled 9.5 16 PDB header:immune system Chain: C: PDB Molecule:h-2 class i histocompatibility antigen, k-k PDBTitle: crystal structure of class i mhc h-2kk in complex with a2 nonapeptide 65 c3ssbJ_ not modelled 9.1 41 PDB header:hydrolase/hydrolase inhibitor Chain: J: PDB Molecule:inducible metalloproteinase inhibitor protein; PDBTitle: structure of insect metalloproteinase inhibitor in complex with2 thermolysin 66 c1sebB_ not modelled 8.7 21 PDB header:complex (mhc ii/peptide/toxin) Chain: B: PDB Molecule:hla class ii histocompatibility antigen; PDBTitle: complex of the human mhc class ii glycoprotein hla-dr1 and2 the bacterial superantigen seb 67 c1ypzA_ not modelled 8.3 17 PDB header:immune system Chain: A: PDB Molecule:h2-t22 protein; PDBTitle: immune receptor 68 c2kykA_ not modelled 8.3 31 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase itchy homolog; PDBTitle: the sandwich region between two lmp2a py motif regulates the2 interaction between aip4ww2domain and py motif 69 d1twfj_ not modelled 8.3 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:RNA polymerase subunit RPB10 Family:RNA polymerase subunit RPB10 70 c3g27A_ not modelled 7.7 58 PDB header:protein binding Chain: A: PDB Molecule:82 prophage-derived uncharacterized protein ybco; PDBTitle: structure of a putative bacteriophage protein from escherichia coli2 str. k-12 substr. mg1655 71 c2le2B_ not modelled 7.7 26 PDB header:hydrolase inhibitor Chain: B: PDB Molecule:p56; PDBTitle: novel dimeric structure of phage phi29-encoded protein p56: insights2 into uracil-dna glycosylase inhibition 72 c3lqzB_ not modelled 7.6 19 PDB header:immune system Chain: B: PDB Molecule:hla-dp2 beta chain linked with dra peptide; PDBTitle: crystal structure of hla-dp2 73 c1s9vA_ not modelled 7.3 21 PDB header:immune system Chain: A: PDB Molecule:hla class ii histocompatibility antigen, dq(3) PDBTitle: crystal structure of hla-dq2 complexed with deamidated2 gliadin peptide 74 c1f3jD_ not modelled 7.1 17 PDB header:immune system Chain: D: PDB Molecule:h-2 class ii histocompatibility antigen; PDBTitle: histocompatibility antigen i-ag7 75 c2ysdA_ not modelled 6.8 40 PDB header:protein binding Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: solution structure of the first ww domain from the human2 membrane-associated guanylate kinase, ww and pdz domain-3 containing protein 1. magi-1 76 d1xoda1 not modelled 6.8 11 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Enabled/VASP homology 1 domain (EVH1 domain) 77 c2kxqA_ not modelled 6.8 33 PDB header:protein binding Chain: A: PDB Molecule:e3 ubiquitin-protein ligase smurf2; PDBTitle: solution structure of smurf2 ww2 and ww3 bound to smad7 py motif2 containing peptide 78 c1p4lA_ not modelled 6.8 16 PDB header:immune system Chain: A: PDB Molecule:mhc class i h-2kb heavy chain; PDBTitle: crystal structure of nk receptor ly49c mutant with its mhc2 class i ligand h-2kb 79 c1cd1C_ not modelled 6.7 18 PDB header:cd1 Chain: C: PDB Molecule:cd1; PDBTitle: cd1(mouse) antigen presenting molecule 80 d1kn6a_ not modelled 6.4 24 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Prohormone convertase 1 pro-domain 81 c2l2lA_ not modelled 6.3 29 PDB header:transferase Chain: A: PDB Molecule:transcriptional repressor p66-alpha; PDBTitle: solution structure of the coiled-coil complex between mbd2 and2 p66alpha 82 c2fwoA_ not modelled 6.3 16 PDB header:immune system/viral protein Chain: A: PDB Molecule:h-2 class i histocompatibility antigen, k-d PDBTitle: mhc class i h-2kd heavy chain in complex with beta-2 2microglobulin and peptide derived from influenza3 nucleoprotein 83 c2j42A_ not modelled 6.2 22 PDB header:toxin Chain: A: PDB Molecule:c2 toxin component-ii; PDBTitle: low quality crystal structure of the transport component c2-2 ii of the c2-toxin from clostridium botulinum 84 d1bdfa1 not modelled 6.1 37 Fold:DCoH-like Superfamily:RBP11-like subunits of RNA polymerase Family:RNA polymerase alpha subunit dimerisation domain 85 d1mr1c_ not modelled 5.8 20 Fold:SAND domain-like Superfamily:SAND domain-like Family:SMAD4-binding domain of oncoprotein Ski 86 c1xz0A_ not modelled 5.7 18 PDB header:immune system Chain: A: PDB Molecule:t-cell surface glycoprotein cd1a; PDBTitle: crystal structure of cd1a in complex with a synthetic mycobactin2 lipopeptide 87 c2ysiA_ not modelled 5.6 8 PDB header:protein binding Chain: A: PDB Molecule:transcription elongation regulator 1; PDBTitle: solution structure of the first ww domain from the mouse2 transcription elongation regulator 1, transcription factor3 ca150 88 c2f0cC_ not modelled 5.4 20 PDB header:virus/viral protein Chain: C: PDB Molecule:phage tp901-1 orf49 (bpp); PDBTitle: structure of the receptor binding protein (orf49, bbp) from lactophage2 tp901-1 89 c1mwaH_ not modelled 5.2 16 PDB header:immune system Chain: H: PDB Molecule:h-2kbm3 mhc class i molecule heavy chain; PDBTitle: 2c/h-2kbm3/dev8 allogeneic complex 90 c1mwaI_ not modelled 5.2 16 PDB header:immune system Chain: I: PDB Molecule:h-2kbm3 mhc class i molecule heavy chain; PDBTitle: 2c/h-2kbm3/dev8 allogeneic complex 91 c1zt4C_ not modelled 5.2 18 PDB header:immune system Chain: C: PDB Molecule:t-cell surface glycoprotein cd1d; PDBTitle: the crystal structure of human cd1d with and without alpha-2 galactosylceramide 92 d1smya1 not modelled 5.2 37 Fold:DCoH-like Superfamily:RBP11-like subunits of RNA polymerase Family:RNA polymerase alpha subunit dimerisation domain 93 d1d5mb1 not modelled 5.2 21 Fold:Immunoglobulin-like beta-sandwich Superfamily:Immunoglobulin Family:C1 set domains (antibody constant domain-like)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0