Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	R	Q	V	I	Q	R	I	S	N	P	E	A	S	I	E	S	L	Q	E	R	R	F	W	L	Q	C	E	R	A	Y	T	W	Q	P	I	Y	Q	T	C	G	R	L	M	A	V	E	L	L	T	V	V	T	H	P	L	N	P	S
Secondary structure
SS confidence
Disorder		?	?																																																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	R	L	P	P	D	R	Y	F	T	E	I	T	V	S	H	R	M	E	V	V	K	E	Q	I	D	L	L	A	Q	K	A	D	F	F	I	E	H	G	L	L	A	S	V	N	I	D	G	P	T	L	I	A	L	R	Q	Q	P	K	I
Secondary structure
SS confidence
Disorder		?																																				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	R	Q	I	E	R	L	P	W	L	R	F	E	L	V	E	H	I	R	L	P	K	D	S	T	F	A	S	M	C	E	F	G	P	L	W	L	D	D	F	G	T	G	M	A	N	F	S	A	L	S	E	V	R	Y	D	Y	I	K	I
Secondary structure
SS confidence
Disorder																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	R	E	L	F	V	M	L	R	Q	S	P	E	G	R	T	L	F	S	Q	L	L	H	L	M	N	R	Y	C	R	G	V	I	V	E	G	V	E	T	P	E	E	W	R	D	V	Q	N	S	P	A	F	A	A	Q	G	W	F	L	S
Secondary structure
SS confidence
Disorder								?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
Sequence		R	P	A	P	I	E	T	L	N	T	A	V	L	A	L
Secondary structure
SS confidence
Disorder															?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3hvb chain B Region: 5 - 247 Aligned: 234 Modelled: 235 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:protein fimx; PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa Phyre2 PDB 3hv9 chain A Region: 1 - 248 Aligned: 239 Modelled: 242 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:protein fimx; PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa Phyre2 PDB 3s83 chain A Region: 11 - 252 Aligned: 231 Modelled: 242 Confidence: 100.0% Identity: 19% PDB header:signaling protein Chain: A: PDB Molecule:ggdef family protein; PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15 Phyre2 PDB 3pjw chain A Region: 10 - 245 Aligned: 226 Modelled: 236 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 Phyre2 PDB 3gfz chain B Region: 22 - 242 Aligned: 215 Modelled: 221 Confidence: 100.0% Identity: 19% PDB header:hydrolase, signaling protein Chain: B: PDB Molecule:klebsiella pneumoniae blrp1; PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex Phyre2 PDB 3pfm chain A Region: 6 - 245 Aligned: 230 Modelled: 230 Confidence: 100.0% Identity: 18% PDB header:signaling protein Chain: A: PDB Molecule:ggdef domain protein; PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf Phyre2 PDB 2w27 chain A Region: 27 - 244 Aligned: 211 Modelled: 216 Confidence: 100.0% Identity: 15% PDB header:signaling protein Chain: A: PDB Molecule:ykui protein; PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium Phyre2 PDB 2r6o chain B Region: 9 - 252 Aligned: 226 Modelled: 242 Confidence: 100.0% Identity: 21% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans Phyre2 PDB 2bas chain A domain 1 Region: 14 - 254 Aligned: 229 Modelled: 241 Confidence: 100.0% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: EAL domain-like Family: EAL domain Phyre2 PDB 3kzp chain A Region: 29 - 245 Aligned: 213 Modelled: 217 Confidence: 100.0% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase; PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes Phyre2 PDB 1p6q chain A Region: 127 - 255 Aligned: 120 Modelled: 120 Confidence: 94.0% Identity: 12% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1hey chain A Region: 128 - 252 Aligned: 116 Modelled: 125 Confidence: 93.5% Identity: 17% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3eul chain B Region: 127 - 254 Aligned: 118 Modelled: 128 Confidence: 93.0% Identity: 14% PDB header:transcription Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis Phyre2 PDB 3kht chain A Region: 131 - 255 Aligned: 116 Modelled: 121 Confidence: 93.0% Identity: 10% PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator from hahella chejuensis Phyre2 PDB 1dz3 chain A Region: 130 - 252 Aligned: 114 Modelled: 123 Confidence: 92.9% Identity: 11% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 1mvo chain A Region: 131 - 252 Aligned: 110 Modelled: 122 Confidence: 92.2% Identity: 12% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3heb chain B Region: 130 - 255 Aligned: 117 Modelled: 126 Confidence: 91.5% Identity: 13% PDB header:transcription regulator Chain: B: PDB Molecule:response regulator receiver domain protein (chey); PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum Phyre2 PDB 2zay chain A Region: 131 - 252 Aligned: 112 Modelled: 122 Confidence: 91.4% Identity: 16% PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans Phyre2 PDB 1jbe chain A Region: 126 - 255 Aligned: 120 Modelled: 130 Confidence: 89.7% Identity: 13% Fold: Flavodoxin-like Superfamily: CheY-like Family: CheY-related Phyre2 PDB 3b2n chain A Region: 129 - 252 Aligned: 114 Modelled: 124 Confidence: 89.5% Identity: 14% PDB header:transcription Chain: A: PDB Molecule:uncharacterized protein q99uf4; PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus Phyre2 1 c3hvbB_ 2 c3hv9A_ 3 c3s83A_ 4 c3pjwA_ 5 c3gfzB_ 6 c3pfmA_ 7 c2w27A_ 8 c2r6oB_ 9 d2basa1 10 c3kzpA_ 11 d1p6qa_ 12 d1heya_ 13 c3eulB_ 14 c3khtA_ 15 d1dz3a_ 16 d1mvoa_ 17 c3hebB_ 18 c2zayA_ 19 d1jbea_ 20 c3b2nA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3hvbB_ 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:protein fimx; PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa 2 c3hv9A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:protein fimx; PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa 3 c3s83A_ 100.0 19 PDB header:signaling protein Chain: A: PDB Molecule:ggdef family protein; PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15 4 c3pjwA_ 100.0 18 PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 5 c3gfzB_ 100.0 19 PDB header:hydrolase, signaling protein Chain: B: PDB Molecule:klebsiella pneumoniae blrp1; PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex 6 c3pfmA_ 100.0 18 PDB header:signaling protein Chain: A: PDB Molecule:ggdef domain protein; PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf 7 c2w27A_ 100.0 15 PDB header:signaling protein Chain: A: PDB Molecule:ykui protein; PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium 8 c2r6oB_ 100.0 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans 9 d2basa1 100.0 14 Fold:TIM beta/alpha-barrel Superfamily:EAL domain-like Family:EAL domain 10 c3kzpA_ 100.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase; PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes 11 d1p6qa_ 94.0 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 12 d1heya_ 93.5 17 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 13 c3eulB_ 93.0 14 PDB header:transcription Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis 14 c3khtA_ 93.0 10 PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator from hahella chejuensis 15 d1dz3a_ 92.9 11 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 16 d1mvoa_ 92.2 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 17 c3hebB_ 91.5 13 PDB header:transcription regulator Chain: B: PDB Molecule:response regulator receiver domain protein (chey); PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum 18 c2zayA_ 91.4 16 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans 19 d1jbea_ 89.7 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 20 c3b2nA_ 89.5 14 PDB header:transcription Chain: A: PDB Molecule:uncharacterized protein q99uf4; PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus 21 d2ayxa1 not modelled 88.8 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 22 d1w25a1 not modelled 88.6 17 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 23 c3gt7A_ not modelled 87.4 21 PDB header:hydrolase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of signal receiver domain of signal2 transduction histidine kinase from syntrophus3 aciditrophicus 24 d1qkka_ not modelled 86.4 15 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 25 c2pz0B_ not modelled 85.8 8 PDB header:hydrolase Chain: B: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of glycerophosphodiester phosphodiesterase (gdpd)2 from t. tengcongensis 26 c2ayxA_ not modelled 85.2 14 PDB header:transferase Chain: A: PDB Molecule:sensor kinase protein rcsc; PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain 27 d2r25b1 not modelled 84.9 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 28 c3i42A_ not modelled 84.7 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:response regulator receiver domain protein (chey- PDBTitle: structure of response regulator receiver domain (chey-like)2 from methylobacillus flagellatus 29 c3luaA_ not modelled 84.1 14 PDB header:transcription regulator Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of a signal receiver domain of two component signal2 transduction (histidine kinase) from clostridium thermocellum 30 d1a04a2 not modelled 82.7 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 31 d1zesa1 not modelled 82.6 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 32 c2yxbA_ not modelled 82.2 9 PDB header:isomerase Chain: A: PDB Molecule:coenzyme b12-dependent mutase; PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix 33 c3cnbC_ not modelled 81.1 13 PDB header:dna binding protein Chain: C: PDB Molecule:dna-binding response regulator, merr family; PDBTitle: crystal structure of signal receiver domain of dna binding response2 regulator protein (merr) from colwellia psychrerythraea 34h 34 c3t8yA_ not modelled 80.9 13 PDB header:hydrolase Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate PDBTitle: crystal structure of the response regulator domain of thermotoga2 maritima cheb 35 d1yioa2 not modelled 79.3 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 36 d1ys7a2 not modelled 78.3 15 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 37 d1y0ea_ not modelled 77.0 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 38 c2jk1A_ not modelled 76.8 13 PDB header:dna-binding Chain: A: PDB Molecule:hydrogenase transcriptional regulatory protein hupr1; PDBTitle: crystal structure of the wild-type hupr receiver domain 39 c1w25B_ not modelled 76.7 17 PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp 40 c3cz5B_ not modelled 76.4 11 PDB header:transcription regulator Chain: B: PDB Molecule:two-component response regulator, luxr family; PDBTitle: crystal structure of two-component response regulator, luxr family,2 from aurantimonas sp. si85-9a1 41 c3t6kB_ not modelled 76.4 12 PDB header:signaling protein Chain: B: PDB Molecule:response regulator receiver; PDBTitle: crystal structure of a hypothetical response regulator (caur_3799)2 from chloroflexus aurantiacus j-10-fl at 1.86 a resolution 42 d1k66a_ not modelled 75.4 15 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 43 c2qvgA_ not modelled 75.2 10 PDB header:transferase Chain: A: PDB Molecule:two component response regulator; PDBTitle: the crystal structure of a two-component response regulator2 from legionella pneumophila 44 d1kgsa2 not modelled 75.1 11 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 45 c3f6cB_ not modelled 74.2 13 PDB header:dna binding protein Chain: B: PDB Molecule:positive transcription regulator evga; PDBTitle: crystal structure of n-terminal domain of positive transcription2 regulator evga from escherichia coli 46 d1rd5a_ not modelled 74.0 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 47 c3nhzA_ not modelled 73.9 16 PDB header:dna binding protein Chain: A: PDB Molecule:two component system transcriptional regulator mtra; PDBTitle: structure of n-terminal domain of mtra 48 d2a9pa1 not modelled 73.4 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 49 c2qr3A_ not modelled 73.3 8 PDB header:transcription Chain: A: PDB Molecule:two-component system response regulator; PDBTitle: crystal structure of the n-terminal signal receiver domain of two-2 component system response regulator from bacteroides fragilis 50 d1h5ya_ not modelled 73.1 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 51 c3c3mA_ not modelled 72.8 12 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of the n-terminal domain of response regulator2 receiver protein from methanoculleus marisnigri jr1 52 c3ktsA_ not modelled 72.5 25 PDB header:transcriptional regulator Chain: A: PDB Molecule:glycerol uptake operon antiterminator regulatory protein; PDBTitle: crystal structure of glycerol uptake operon antiterminator regulatory2 protein from listeria monocytogenes str. 4b f2365 53 c3cu5B_ not modelled 72.3 13 PDB header:transcription regulator Chain: B: PDB Molecule:two component transcriptional regulator, arac family; PDBTitle: crystal structure of a two component transcriptional regulator arac2 from clostridium phytofermentans isdg 54 d1i3ca_ not modelled 72.1 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 55 c3gl9B_ not modelled 70.7 15 PDB header:signaling protein Chain: B: PDB Molecule:response regulator; PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism 56 c3h1gA_ not modelled 69.5 9 PDB header:signaling protein Chain: A: PDB Molecule:chemotaxis protein chey homolog; PDBTitle: crystal structure of chey mutant t84a of helicobacter pylori 57 c2zwmA_ not modelled 68.0 12 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein yycf; PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis 58 c3lteH_ not modelled 67.3 11 PDB header:transcription Chain: H: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator (signal receiver domain) from2 bermanella marisrubri 59 d1krwa_ not modelled 67.1 16 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 60 c3edeB_ not modelled 66.9 17 PDB header:hydrolase Chain: B: PDB Molecule:cyclomaltodextrinase; PDBTitle: structural base for cyclodextrin hydrolysis 61 c3ffsC_ not modelled 66.2 11 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 62 c1zfjA_ not modelled 65.8 16 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 63 d1vd6a1 not modelled 65.4 13 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase 64 c3breA_ not modelled 65.4 12 PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: crystal structure of p.aeruginosa pa3702 65 d1ny5a1 not modelled 65.3 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 66 d1zh2a1 not modelled 64.0 11 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 67 c3rlhA_ not modelled 63.3 10 PDB header:hydrolase Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a; PDBTitle: crystal structure of a class ii phospholipase d from loxosceles2 intermedia venom 68 d1a53a_ not modelled 62.6 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 69 c2p76H_ not modelled 62.2 11 PDB header:hydrolase Chain: H: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphodiester phosphodiesterase from2 staphylococcus aureus 70 c3o63B_ not modelled 62.0 14 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 71 c2qr6A_ not modelled 61.7 18 PDB header:oxidoreductase Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase; PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution 72 c3ch0A_ not modelled 61.7 15 PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of glycerophosphoryl diester phosphodiesterase2 (yp_677622.1) from cytophaga hutchinsonii atcc 33406 at 1.50 a3 resolution 73 c2y85D_ not modelled 61.6 20 PDB header:isomerase Chain: D: PDB Molecule:phosphoribosyl isomerase a; PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp 74 c3c97A_ not modelled 59.4 15 PDB header:signaling protein, transferase Chain: A: PDB Molecule:signal transduction histidine kinase; PDBTitle: crystal structure of the response regulator receiver domain2 of a signal transduction histidine kinase from aspergillus3 oryzae 75 d1ua7a2 not modelled 59.1 14 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 76 d1s8na_ not modelled 58.9 18 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 77 c3l12A_ not modelled 58.3 16 PDB header:hydrolase Chain: A: PDB Molecule:putative glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (yp_165505.1) from silicibacter pomeroyi dss-3 at3 1.60 a resolution 78 d1xi3a_ not modelled 57.8 9 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 79 c3r0jA_ not modelled 57.7 11 PDB header:dna binding protein Chain: A: PDB Molecule:possible two component system response transcriptional PDBTitle: structure of phop from mycobacterium tuberculosis 80 c2rjnA_ not modelled 57.5 16 PDB header:hydrolase Chain: A: PDB Molecule:response regulator receiver:metal-dependent PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis 81 c3es8D_ not modelled 57.2 6 PDB header:isomerase, lyase Chain: D: PDB Molecule:muconate cycloisomerase; PDBTitle: crystal structure of divergent enolase from oceanobacillus2 iheyensis complexed with mg and l-malate. 82 d1qwga_ not modelled 56.9 15 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 83 d1u0sy_ not modelled 56.6 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 84 d1zgza1 not modelled 56.6 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 85 c3r2gA_ not modelled 55.4 13 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase; PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila 86 d1gjwa2 not modelled 55.3 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 87 c2h6rG_ not modelled 54.9 10 PDB header:isomerase Chain: G: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii 88 d1vc4a_ not modelled 54.4 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 89 c3cg0A_ not modelled 54.0 17 PDB header:lyase Chain: A: PDB Molecule:response regulator receiver modulated diguanylate cyclase PDBTitle: crystal structure of signal receiver domain of modulated diguanylate2 cyclase from desulfovibrio desulfuricans g20, an example of alternate3 folding 90 c2qv0A_ not modelled 53.6 13 PDB header:transcription Chain: A: PDB Molecule:protein mrke; PDBTitle: crystal structure of the response regulatory domain of2 protein mrke from klebsiella pneumoniae 91 c3hdgE_ not modelled 53.5 9 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the n-terminal domain of an2 uncharacterized protein (ws1339) from wolinella3 succinogenes 92 d1xhfa1 not modelled 53.1 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 93 c2j48A_ not modelled 52.7 16 PDB header:transferase Chain: A: PDB Molecule:two-component sensor kinase; PDBTitle: nmr structure of the pseudo-receiver domain of the cika2 protein. 94 d2tpsa_ not modelled 52.3 12 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 95 c3bw2A_ not modelled 52.3 20 PDB header:oxidoreductase Chain: A: PDB Molecule:2-nitropropane dioxygenase; PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes 96 c1qhoA_ not modelled 52.0 21 PDB header:hydrolase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: five-domain alpha-amylase from bacillus stearothermophilus,2 maltose/acarbose complex 97 d1dbwa_ not modelled 52.0 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 98 c1u83A_ not modelled 50.8 14 PDB header:lyase Chain: A: PDB Molecule:phosphosulfolactate synthase; PDBTitle: psl synthase from bacillus subtilis 99 d1u83a_ not modelled 50.8 14 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 100 c3ilhA_ not modelled 50.8 11 PDB header:transcription regulator Chain: A: PDB Molecule:two component response regulator; PDBTitle: crystal structure of two component response regulator from cytophaga2 hutchinsonii 101 c3hzhA_ not modelled 50.7 9 PDB header:signaling protein Chain: A: PDB Molecule:chemotaxis response regulator (chey-3); PDBTitle: crystal structure of the chex-chey-bef3-mg+2 complex from2 borrelia burgdorferi 102 d1zfja1 not modelled 50.6 11 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 103 c2nt3A_ not modelled 50.2 16 PDB header:signaling protein Chain: A: PDB Molecule:response regulator homolog; PDBTitle: receiver domain from myxococcus xanthus social motility protein frzs2 (y102a mutant) 104 d1mb3a_ not modelled 49.4 16 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 105 c3snkA_ not modelled 49.2 13 PDB header:signaling protein Chain: A: PDB Molecule:response regulator chey-like protein; PDBTitle: crystal structure of a response regulator chey-like protein (mll6475)2 from mesorhizobium loti at 2.02 a resolution 106 d1pdza1 not modelled 49.1 11 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:Enolase 107 c2qzjC_ not modelled 48.7 17 PDB header:transcription Chain: C: PDB Molecule:two-component response regulator; PDBTitle: crystal structure of a two-component response regulator from2 clostridium difficile 108 c3a0rB_ not modelled 48.0 13 PDB header:transferase Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360) 109 c3crnA_ not modelled 47.6 14 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver domain protein, chey-like; PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1 110 c2chrA_ not modelled 47.6 10 PDB header:isomerase Chain: A: PDB Molecule:chloromuconate cycloisomerase; PDBTitle: a re-evaluation of the crystal structure of chloromuconate2 cycloisomerase 111 c3qjaA_ not modelled 47.6 11 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 112 c2otdC_ not modelled 47.0 8 PDB header:hydrolase Chain: C: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: the crystal structure of the glycerophosphodiester phosphodiesterase2 from shigella flexneri 2a 113 c2jrlA_ not modelled 46.6 15 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer 114 c3m6mF_ not modelled 46.4 24 PDB header:lyase/transferase Chain: F: PDB Molecule:sensory/regulatory protein rpfc; PDBTitle: crystal structure of rpff complexed with rec domain of rpfc 115 c2a7rD_ not modelled 46.3 11 PDB header:oxidoreductase Chain: D: PDB Molecule:gmp reductase 2; PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2) 116 c3kruC_ not modelled 45.9 15 PDB header:oxidoreductase Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39 117 c3hv2B_ not modelled 45.8 14 PDB header:signaling protein Chain: B: PDB Molecule:response regulator/hd domain protein; PDBTitle: crystal structure of signal receiver domain of hd domain-2 containing protein from pseudomonas fluorescens pf-5 118 d1piia2 not modelled 44.8 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 119 c3ktoA_ not modelled 44.3 12 PDB header:transcription regulator Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator receiver protein2 from pseudoalteromonas atlantica 120 c3ozbF_ not modelled 44.2 18 PDB header:transferase Chain: F: PDB Molecule:methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-methylthioinosine phosphorylase from2 psedomonas aeruginosa in complex with hypoxanthine

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0