Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP54746
DateThu Jan 5 12:06:04 GMT 2012
Unique Job ID73dfd56774d8362b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2wyhA_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:alpha-mannosidase;
PDBTitle: structure of the streptococcus pyogenes family gh38 alpha-2 mannosidase
Confidence and coverage
Confidence:100.0% Coverage: 95%
835 residues ( 95% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILE
Secondary structure 
SS confidence 
Disorder  ?????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  DYFAVKPENKDRVKKQVEAGKLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMK
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  IGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDKTEFLWQSSDGSEVTAQVLPL
Secondary structure 
SS confidence 
Disorder 
???
??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  GYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMDKLREI
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  YPQRKFVMSRFEEVFEKIEAQRDNLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIEN
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  KIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELA
Secondary structure 
SS confidence 
Disorder 
?
???
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  EDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEVINTTVRLRASQFNLRDDRGQ
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  PVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVI
Secondary structure 
SS confidence 
Disorder 
??????
?
?
?
????
?
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  AAKSDAEGILENAFWQIALNEDGSLQLVDKDSGVRYDRVLQIEESSDDGDEYDYSPAKEE
Secondary structure 
SS confidence 
Disorder 
?????
?
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  WVITAANAKPQCDIIHEAWQSRAVIRYDMAVPLNLSERSARQSTGRVGVVLVVTLSHNSR
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  RIDVDINLDNQADDHRLRVLVPTPFNTDSVLADTQFGSLTRPVNDSAMNNWQQEGWKEAP
Secondary structure 
SS confidence 
Disorder 
?
?
?
???
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  VPVWNMLNYVALQEGRNGMAVFSEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLLLRPG
Secondary structure 
SS confidence 
Disorder 
???
??
?
??
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDVMKL
Secondary structure 
SS confidence 
Disorder  ??
????????
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  NKAGFNVPESYSLLKMPPVGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVIS
Secondary structure 
SS confidence 
Disorder  ????????
?
Disorder confidence 
 
   .........850.........860.........870.......
Sequence  CSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA
Secondary structure 
SS confidence 
Disorder 
??????????
?
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2wyh chain A

3D model

Region: 1 - 875
Aligned: 835
Modelled: 863
Confidence: 100.0%
Identity: 29%
PDB header:hydrolase
Chain: A: PDB Molecule:alpha-mannosidase;
PDBTitle: structure of the streptococcus pyogenes family gh38 alpha-2 mannosidase

Phyre2

PDB 3lvt chain A

3D model

Region: 2 - 875
Aligned: 789
Modelled: 838
Confidence: 100.0%
Identity: 27%
PDB header:hydrolase
Chain: A: PDB Molecule:glycosyl hydrolase, family 38;
PDBTitle: the crystal structure of a protein in the glycosyl hydrolase2 family 38 from enterococcus faecalis to 2.55a

Phyre2

PDB 1hty chain A

3D model

Region: 2 - 877
Aligned: 828
Modelled: 835
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:alpha-mannosidase ii;
PDBTitle: golgi alpha-mannosidase ii

Phyre2

PDB 2ow7 chain A

3D model

Region: 2 - 877
Aligned: 821
Modelled: 844
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:alpha-mannosidase 2;
PDBTitle: golgi alpha-mannosidase ii complex with (1r,6s,7r,8s)-1-2 thioniabicyclo[4.3.0]nonan-7,8-diol chloride

Phyre2

PDB 3bvu chain A domain 3

3D model

Region: 1 - 277
Aligned: 276
Modelled: 277
Confidence: 100.0%
Identity: 19%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: alpha-mannosidase

Phyre2

PDB 1o7d chain A

3D model

Region: 2 - 239
Aligned: 237
Modelled: 237
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation

Phyre2

PDB 3bvu chain A domain 2

3D model

Region: 386 - 877
Aligned: 446
Modelled: 473
Confidence: 100.0%
Identity: 13%
Fold: Supersandwich
Superfamily: Galactose mutarotase-like
Family: alpha-mannosidase, C-terminal domain

Phyre2

PDB 1k1x chain A domain 3

3D model

Region: 1 - 299
Aligned: 281
Modelled: 285
Confidence: 100.0%
Identity: 15%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: 4-alpha-glucanotransferase, N-terminal domain

Phyre2

PDB 1o7d chain D

3D model

Region: 486 - 771
Aligned: 251
Modelled: 268
Confidence: 100.0%
Identity: 12%
PDB header:hydrolase
Chain: D: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation

Phyre2

PDB 1k1y chain A

3D model

Region: 1 - 422
Aligned: 384
Modelled: 400
Confidence: 99.9%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:4-alpha-glucanotransferase;
PDBTitle: crystal structure of thermococcus litoralis 4-alpha-glucanotransferase2 complexed with acarbose

Phyre2

PDB 1o7d chain C

3D model

Region: 325 - 475
Aligned: 131
Modelled: 133
Confidence: 99.9%
Identity: 11%
PDB header:hydrolase
Chain: C: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation

Phyre2

PDB 3bvu chain A domain 1

3D model

Region: 280 - 385
Aligned: 105
Modelled: 106
Confidence: 99.9%
Identity: 15%
Fold: immunoglobulin/albumin-binding domain-like
Superfamily: Families 57/38 glycoside transferase middle domain
Family: alpha-mannosidase, domain 2

Phyre2

PDB 1o7d chain B

3D model

Region: 243 - 314
Aligned: 71
Modelled: 72
Confidence: 99.5%
Identity: 14%
PDB header:hydrolase
Chain: B: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation

Phyre2

PDB 2b5d chain X

3D model

Region: 6 - 368
Aligned: 341
Modelled: 344
Confidence: 99.5%
Identity: 14%
PDB header:hydrolase
Chain: X: PDB Molecule:alpha-amylase;
PDBTitle: crystal structure of the novel alpha-amylase amyc from thermotoga2 maritima

Phyre2

PDB 1ufa chain A

3D model

Region: 4 - 375
Aligned: 357
Modelled: 360
Confidence: 99.4%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tt1467 protein;
PDBTitle: crystal structure of tt1467 from thermus thermophilus hb8

Phyre2

PDB 3n92 chain A

3D model

Region: 1 - 370
Aligned: 360
Modelled: 367
Confidence: 99.3%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:alpha-amylase, gh57 family;
PDBTitle: crystal structure of tk1436, a gh57 branching enzyme from2 hyperthermophilic archaeon thermococcus kodakaraensis, in complex3 with glucose

Phyre2

PDB 2b5d chain X domain 2

3D model

Region: 6 - 257
Aligned: 244
Modelled: 252
Confidence: 99.3%
Identity: 16%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: AmyC N-terminal domain-like

Phyre2

PDB 1ufa chain A domain 2

3D model

Region: 4 - 256
Aligned: 252
Modelled: 252
Confidence: 99.0%
Identity: 16%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: AmyC N-terminal domain-like

Phyre2

PDB 1o7d chain E

3D model

Region: 787 - 876
Aligned: 89
Modelled: 90
Confidence: 98.6%
Identity: 17%
PDB header:hydrolase
Chain: E: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation

Phyre2

PDB 3qbu chain D

3D model

Region: 13 - 264
Aligned: 242
Modelled: 243
Confidence: 98.1%
Identity: 12%
PDB header:hydrolase
Chain: D: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of putative peptidoglyacn deactelyase (hp0310) from2 helicobacter pylori

Phyre2
1
c2wyhA_
2
c3lvtA_
3
c1htyA_
4
c2ow7A_
5
d3bvua3
6
c1o7dA_
7
d3bvua2
8
d1k1xa3
9
c1o7dD_
10
c1k1yA_
11
c1o7dC_
12
d3bvua1
13
c1o7dB_
14
c2b5dX_
15
c1ufaA_
16
c3n92A_
17
d2b5dx2
18
d1ufaa2
19
c1o7dE_
20
c3qbuD_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
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78
79
80
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2wyhA_
100.0 29 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-mannosidase;
PDBTitle: structure of the streptococcus pyogenes family gh38 alpha-2 mannosidase
2c3lvtA_
100.0 27 PDB header:hydrolase
Chain: A: PDB Molecule:glycosyl hydrolase, family 38;
PDBTitle: the crystal structure of a protein in the glycosyl hydrolase2 family 38 from enterococcus faecalis to 2.55a
3c1htyA_
100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-mannosidase ii;
PDBTitle: golgi alpha-mannosidase ii
4c2ow7A_
100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-mannosidase 2;
PDBTitle: golgi alpha-mannosidase ii complex with (1r,6s,7r,8s)-1-2 thioniabicyclo[4.3.0]nonan-7,8-diol chloride
5d3bvua3
100.0 19 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:alpha-mannosidase
6c1o7dA_
100.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation
7d3bvua2
100.0 13 Fold:Supersandwich
Superfamily:Galactose mutarotase-like
Family:alpha-mannosidase, C-terminal domain
8d1k1xa3
100.0 15 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:4-alpha-glucanotransferase, N-terminal domain
9c1o7dD_
100.0 12 PDB header:hydrolase
Chain: D: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation
10c1k1yA_
99.9 14 PDB header:transferase
Chain: A: PDB Molecule:4-alpha-glucanotransferase;
PDBTitle: crystal structure of thermococcus litoralis 4-alpha-glucanotransferase2 complexed with acarbose
11c1o7dC_
99.9 11 PDB header:hydrolase
Chain: C: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation
12d3bvua1
99.9 15 Fold:immunoglobulin/albumin-binding domain-like
Superfamily:Families 57/38 glycoside transferase middle domain
Family:alpha-mannosidase, domain 2
13c1o7dB_
99.5 14 PDB header:hydrolase
Chain: B: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation
14c2b5dX_
99.5 14 PDB header:hydrolase
Chain: X: PDB Molecule:alpha-amylase;
PDBTitle: crystal structure of the novel alpha-amylase amyc from thermotoga2 maritima
15c1ufaA_
99.4 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tt1467 protein;
PDBTitle: crystal structure of tt1467 from thermus thermophilus hb8
16c3n92A_
99.3 17 PDB header:transferase
Chain: A: PDB Molecule:alpha-amylase, gh57 family;
PDBTitle: crystal structure of tk1436, a gh57 branching enzyme from2 hyperthermophilic archaeon thermococcus kodakaraensis, in complex3 with glucose
17d2b5dx2
99.3 16 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:AmyC N-terminal domain-like
18d1ufaa2
99.0 16 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:AmyC N-terminal domain-like
19c1o7dE_
98.6 17 PDB header:hydrolase
Chain: E: PDB Molecule:lysosomal alpha-mannosidase;
PDBTitle: the structure of the bovine lysosomal a-mannosidase2 suggests a novel mechanism for low ph activation
20c3qbuD_
98.1 12 PDB header:hydrolase
Chain: D: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of putative peptidoglyacn deactelyase (hp0310) from2 helicobacter pylori
21c3rxzA_
not modelled 97.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:polysaccharide deacetylase;
PDBTitle: crystal structure of putative polysaccharide deacetylase from2 mycobacterium smegmatis
22d1z7aa1
not modelled 97.6 11 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:PA1517-like
23c3s6oD_
not modelled 97.2 12 PDB header:hydrolase
Chain: D: PDB Molecule:polysaccharide deacetylase family protein;
PDBTitle: crystal structure of a polysaccharide deacetylase family protein from2 burkholderia pseudomallei
24c2c1iA_
not modelled 97.1 18 PDB header:hydrolase
Chain: A: PDB Molecule:peptidoglycan glcnac deacetylase;
PDBTitle: structure of streptococcus pnemoniae peptidoglycan2 deacetylase (sppgda) d 275 n mutant.
25c1w17A_
not modelled 97.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:probable polysaccharide deacetylase pdaa;
PDBTitle: structure of bacillus subtilis pdaa, a family 42 carbohydrate esterase.
26c2vyoA_
not modelled 95.2 13 PDB header:hydrolase
Chain: A: PDB Molecule:chitooligosaccharide deacetylase;
PDBTitle: chitin deacetylase family member from encephalitozoon2 cuniculi
27d1ny1a_
not modelled 94.8 15 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
28d2j13a1
not modelled 93.5 15 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
29d2c1ia1
not modelled 93.3 13 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
30d2iw0a1
not modelled 91.7 12 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
31c2iw0A_
not modelled 91.0 9 PDB header:hydrolase
Chain: A: PDB Molecule:chitin deacetylase;
PDBTitle: structure of the chitin deacetylase from the fungal2 pathogen colletotrichum lindemuthianum
32c3dcdA_
not modelled 86.2 8 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:galactose mutarotase related enzyme;
PDBTitle: x-ray structure of the galactose mutarotase related enzyme q5fkd7 from2 lactobacillus acidophilus at the resolution 1.9a. northeast3 structural genomics consortium target lar33.
33d2cc0a1
not modelled 79.0 20 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
34d1nofa1
not modelled 77.5 16 Fold:Glycosyl hydrolase domain
Superfamily:Glycosyl hydrolase domain
Family:Composite domain of glycosyl hydrolase families 5, 30, 39 and 51
35c2w3zA_
not modelled 76.7 20 PDB header:hydrolase
Chain: A: PDB Molecule:putative deacetylase;
PDBTitle: structure of a streptococcus mutans ce4 esterase
36c3cc1B_
not modelled 64.9 11 PDB header:hydrolase
Chain: B: PDB Molecule:putative alpha-n-acetylgalactosaminidase;
PDBTitle: crystal structure of a putative alpha-n-acetylgalactosaminidase2 (bh1870) from bacillus halodurans c-125 at 2.00 a resolution
37d1m53a1
not modelled 64.4 12 Fold:Glycosyl hydrolase domain
Superfamily:Glycosyl hydrolase domain
Family:alpha-Amylases, C-terminal beta-sheet domain
38d1uoka1
not modelled 59.5 10 Fold:Glycosyl hydrolase domain
Superfamily:Glycosyl hydrolase domain
Family:alpha-Amylases, C-terminal beta-sheet domain
39d2c71a1
not modelled 58.5 16 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:NodB-like polysaccharide deacetylase
40c3q1nA_
not modelled 52.0 28 PDB header:isomerase
Chain: A: PDB Molecule:galactose mutarotase related enzyme;
PDBTitle: crystal structure of a galactose mutarotase-like protein (lsei_2598)2 from lactobacillus casei atcc 334 at 1.61 a resolution
41c1qw9B_
not modelled 51.7 8 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-l-arabinofuranosidase;
PDBTitle: crystal structure of a family 51 alpha-l-2 arabinofuranosidase in complex with 4-nitrophenyl-ara
42d1tsja_
not modelled 49.9 38 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Family:3-demethylubiquinone-9 3-methyltransferase
43c3blcB_
not modelled 49.3 7 PDB header:chaperone,protein transport
Chain: B: PDB Molecule:inner membrane protein oxaa;
PDBTitle: crystal structure of the periplasmic domain of the escherichia coli2 yidc
44c3ik2A_
not modelled 48.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase a;
PDBTitle: crystal structure of a glycoside hydrolase family 44 endoglucanase2 produced by clostridium acetobutylium atcc 824
45c1zjaB_
not modelled 47.3 12 PDB header:isomerase
Chain: B: PDB Molecule:trehalulose synthase;
PDBTitle: crystal structure of the trehalulose synthase mutb from2 pseudomonas mesoacidophila mx-45 (triclinic form)
46d1u69a_
not modelled 46.6 38 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Family:3-demethylubiquinone-9 3-methyltransferase
47d1ekja_
not modelled 46.2 10 Fold:Resolvase-like
Superfamily:beta-carbonic anhydrase, cab
Family:beta-carbonic anhydrase, cab
48d1u7ia_
not modelled 45.0 44 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Family:3-demethylubiquinone-9 3-methyltransferase
49c3omsA_
not modelled 44.6 53 PDB header:transferase
Chain: A: PDB Molecule:phnb protein;
PDBTitle: putative 3-demethylubiquinone-9 3-methyltransferase, phnb protein,2 from bacillus cereus.
50c2q48A_
not modelled 43.9 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:protein at5g48480;
PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at5g48480
51d1xy7a_
not modelled 43.9 22 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Family:Hypothetical protein At5g48480
52d1r9ja3
not modelled 42.8 40 Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
53c3bs6B_
not modelled 41.3 5 PDB header:membrane protein, protein transport
Chain: B: PDB Molecule:inner membrane protein oxaa;
PDBTitle: 1.8 angstrom crystal structure of the periplasmic domain of2 the membrane insertase yidc
54c3l20A_
not modelled 38.8 33 PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein from staphylococcus aureus
55d1wzla2
not modelled 38.6 13 Fold:Glycosyl hydrolase domain
Superfamily:Glycosyl hydrolase domain
Family:alpha-Amylases, C-terminal beta-sheet domain
56d2ieaa3
not modelled 38.2 25 Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
57d1u6la_
not modelled 37.4 27 Fold:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Superfamily:Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
Family:3-demethylubiquinone-9 3-methyltransferase
58c2ze0A_
not modelled 36.3 13 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-glucosidase;
PDBTitle: alpha-glucosidase gsj
59c3a5vA_
not modelled 34.3 10 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-galactosidase;
PDBTitle: crystal structure of alpha-galactosidase i from mortierella vinacea
60c2a5hC_
not modelled 34.1 15 PDB header:isomerase
Chain: C: PDB Molecule:l-lysine 2,3-aminomutase;
PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate).
61c1ktbA_
not modelled 33.2 10 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase;
PDBTitle: the structure of alpha-n-acetylgalactosaminidase
62c2jgdA_
not modelled 32.7 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-oxoglutarate dehydrogenase e1 component;
PDBTitle: e. coli 2-oxoglutarate dehydrogenase (e1o)
63c1nofA_
not modelled 32.2 16 PDB header:hydrolase
Chain: A: PDB Molecule:xylanase;
PDBTitle: the first crystallographic structure of a xylanase from2 glycosyl hydrolase family 5: implications for catalysis
64d1j0ha2
not modelled 31.7 13 Fold:Glycosyl hydrolase domain
Superfamily:Glycosyl hydrolase domain
Family:alpha-Amylases, C-terminal beta-sheet domain
65c2yicC_
not modelled 31.3 18 PDB header:lyase
Chain: C: PDB Molecule:2-oxoglutarate decarboxylase;
PDBTitle: crystal structure of the suca domain of mycobacterium smegmatis2 alpha-ketoglutarate decarboxylase (triclinic form)
66d1itza3
not modelled 30.8 45 Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
67c1r46B_
not modelled 30.0 10 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-galactosidase a;
PDBTitle: structure of human alpha-galactosidase
68c1uokA_
not modelled 28.6 10 PDB header:glucosidase
Chain: A: PDB Molecule:oligo-1,6-glucosidase;
PDBTitle: crystal structure of b. cereus oligo-1,6-glucosidase
69d1gpua3
not modelled 28.0 45 Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
70c3fw6A_
not modelled 28.0 10 PDB header:hydrolase
Chain: A: PDB Molecule:cellulase;
PDBTitle: crystal structure of celm2, a bifunctional glucanase-2 xylanase protein from a metagenome library
71c2a5vB_
not modelled 25.6 14 PDB header:lyase
Chain: B: PDB Molecule:carbonic anhydrase (carbonate dehydratase) (carbonic
PDBTitle: crystal structure of m. tuberculosis beta carbonic anhydrase, rv3588c,2 tetrameric form
72c3gtnA_
not modelled 25.3 17 PDB header:hydrolase
Chain: A: PDB Molecule:glucuronoxylanase xync;
PDBTitle: crystal structure of xync from bacillus subtilis 168
73d1ldda_
not modelled 24.8 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:SCF ubiquitin ligase complex WHB domain
74c1m53A_
not modelled 23.3 12 PDB header:isomerase
Chain: A: PDB Molecule:isomaltulose synthase;
PDBTitle: crystal structure of isomaltulose synthase (pali) from2 klebsiella sp. lx3
75c3mwxA_
not modelled 23.2 12 PDB header:isomerase
Chain: A: PDB Molecule:aldose 1-epimerase;
PDBTitle: crystal structure of a putative galactose mutarotase (bsu18360) from2 bacillus subtilis at 1.45 a resolution
76c1gviA_
not modelled 23.0 9 PDB header:hydrolase
Chain: A: PDB Molecule:maltogenic amylase;
PDBTitle: thermus maltogenic amylase in complex with beta-cd
77c2dh3A_
not modelled 21.3 11 PDB header:transport protein, signaling protein
Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain;
PDBTitle: crystal structure of human ed-4f2hc
78d1vi0a2
not modelled 21.2 9 Fold:Tetracyclin repressor-like, C-terminal domain
Superfamily:Tetracyclin repressor-like, C-terminal domain
Family:Tetracyclin repressor-like, C-terminal domain
79d1qw9a1
not modelled 20.4 15 Fold:Glycosyl hydrolase domain
Superfamily:Glycosyl hydrolase domain
Family:Composite domain of glycosyl hydrolase families 5, 30, 39 and 51
80d1j5sa_
not modelled 19.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Uronate isomerase-like
81d1v5ma_
not modelled 19.6 20 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Pleckstrin-homology domain (PH domain)
82c2w3nA_
not modelled 19.1 9 PDB header:lyase
Chain: A: PDB Molecule:carbonic anhydrase 2;
PDBTitle: structure and inhibition of the co2-sensing carbonic2 anhydrase can2 from the pathogenic fungus cryptococcus3 neoformans
83c2y2wC_
not modelled 18.8 8 PDB header:hydrolase
Chain: C: PDB Molecule:arabinofuranosidase;
PDBTitle: elucidation of the substrate specificity and protein2 structure of abfb, a family 51 alpha-l-arabinofuranosidase3 from bifidobacterium longum.
84d1j6wa_
not modelled 18.0 17 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:Autoinducer-2 production protein LuxS
85c2vkzH_
not modelled 17.6 16 PDB header:transferase
Chain: H: PDB Molecule:fatty acid synthase subunit beta;
PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex
86d2r8oa3
not modelled 17.5 30 Fold:TK C-terminal domain-like
Superfamily:TK C-terminal domain-like
Family:Transketolase C-terminal domain-like
87c2hihB_
not modelled 17.3 30 PDB header:hydrolase
Chain: B: PDB Molecule:lipase 46 kda form;
PDBTitle: crystal structure of staphylococcus hyicus lipase
88c2xt6B_
not modelled 17.2 19 PDB header:lyase
Chain: B: PDB Molecule:2-oxoglutarate decarboxylase;
PDBTitle: crystal structure of mycobacterium smegmatis alpha-ketoglutarate2 decarboxylase homodimer (orthorhombic form)
89c2k6xA_
not modelled 16.7 40 PDB header:transcription
Chain: A: PDB Molecule:rna polymerase sigma factor rpod;
PDBTitle: autoregulation of a group 1 bacterial sigma factor involves2 the formation of a region 1.1- induced compacted structure
90c3nreB_
not modelled 15.7 10 PDB header:isomerase
Chain: B: PDB Molecule:aldose 1-epimerase;
PDBTitle: crystal structure of a putative aldose 1-epimerase (b2544) from2 escherichia coli k12 at 1.59 a resolution
91c2g28A_
not modelled 15.2 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate dehydrogenase e1 component;
PDBTitle: e. coli pyruvate dehydrogenase h407a variant2 phosphonolactylthiamin diphosphate complex
92d1lpbb2
not modelled 15.1 36 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Pancreatic lipase, N-terminal domain
93d1nlna_
not modelled 15.1 24 Fold:Cysteine proteinases
Superfamily:Cysteine proteinases
Family:Adenain-like
94d1rp1a2
not modelled 14.4 27 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Pancreatic lipase, N-terminal domain
95c1ygaA_
not modelled 14.3 14 PDB header:isomerase
Chain: A: PDB Molecule:hypothetical 37.9 kda protein in bio3-hxt17
PDBTitle: crystal structure of saccharomyces cerevisiae yn9a protein,2 new york structural genomics consortium
96d1etha2
not modelled 13.7 36 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Pancreatic lipase, N-terminal domain
97d1vioa2
not modelled 13.4 12 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Pseudouridine synthase RsuA N-terminal domain
98c2o1sC_
not modelled 13.2 25 PDB header:transferase
Chain: C: PDB Molecule:1-deoxy-d-xylulose-5-phosphate synthase;
PDBTitle: 1-deoxy-d-xylulose 5-phosphate synthase (dxs) from2 escherichia coli
99d1hpla2
not modelled 12.6 45 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Pancreatic lipase, N-terminal domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0