Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	S	G	R	F	I	G	V	M	S	G	T	S	L	D	G	V	D	V	V	L	A	T	I	D	E	H	R	V	A	Q	L	A	S	L	S	W	P	I	P	V	S	L	K	Q	A	V	L	D	I	C	Q	G	Q	Q	L	T	L	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?																																																	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	F	G	Q	L	D	T	Q	L	G	Q	L	F	A	D	A	V	N	A	L	L	K	E	Q	N	L	Q	A	R	D	I	V	A	I	G	C	H	G	Q	T	V	W	H	E	P	T	G	V	A	P	H	T	L	Q	I	G	D	N	N	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	V	A	R	T	G	I	T	V	V	G	D	F	R	R	R	D	I	A	L	G	G	Q	G	A	P	L	V	P	A	F	H	H	A	L	L	A	H	P	T	E	R	R	M	V	L	N	I	G	G	I	A	N	L	S	L	L	I	P	G
Secondary structure
SS confidence
Disorder																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	P	V	G	G	Y	D	T	G	P	G	N	M	L	M	D	A	W	I	W	R	Q	A	G	K	P	Y	D	K	D	A	E	W	A	R	A	G	K	V	I	L	P	L	L	Q	N	M	L	S	D	P	Y	F	S	Q	P	A	P	K	S
Secondary structure
SS confidence
Disorder																											?	?	?	?	?	?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	G	R	E	Y	F	N	Y	G	W	L	E	R	H	L	R	H	F	P	G	V	D	P	R	D	V	Q	A	T	L	A	E	L	T	A	V	T	I	S	E	Q	V	L	L	S	G	G	C	E	R	L	M	V	C	G	G	G	S	R	N
Secondary structure
SS confidence
Disorder																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		P	L	L	M	A	R	L	A	A	L	L	P	G	T	E	V	T	T	T	D	A	V	G	I	S	G	D	D	M	E	A	L	A	F	A	W	L	A	W	R	T	L	A	G	L	P	G	N	L	P	S	V	T	G	A	S	Q	E	T	V
Secondary structure
SS confidence
Disorder																							?																																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.
Sequence		L	G	A	I	F	P	A	N	P
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3cqy chain A Region: 2 - 367 Aligned: 366 Modelled: 366 Confidence: 100.0% Identity: 48% PDB header:transferase Chain: A: PDB Molecule:anhydro-n-acetylmuramic acid kinase; PDBTitle: crystal structure of a functionally unknown protein (so_1313) from2 shewanella oneidensis mr-1 Phyre2 PDB 3qbw chain A Region: 5 - 366 Aligned: 346 Modelled: 361 Confidence: 100.0% Identity: 49% PDB header:transferase Chain: A: PDB Molecule:anhydro-n-acetylmuramic acid kinase; PDBTitle: crystal structure of pseudomonas aeruginosa 1,6-anhydro-n-2 actetylmuramic acid kinase (anmk) bound to adenosine diphosphate Phyre2 PDB 3eno chain B Region: 1 - 340 Aligned: 289 Modelled: 311 Confidence: 99.2% Identity: 21% PDB header:hydrolase/unknown function Chain: B: PDB Molecule:putative o-sialoglycoprotein endopeptidase; PDBTitle: crystal structure of pyrococcus furiosus pcc1 in complex2 with thermoplasma acidophilum kae1 Phyre2 PDB 2ivo chain C Region: 63 - 344 Aligned: 247 Modelled: 265 Confidence: 98.2% Identity: 17% PDB header:hydrolase Chain: C: PDB Molecule:up1; PDBTitle: structure of up1 protein Phyre2 PDB 1hux chain A Region: 73 - 344 Aligned: 216 Modelled: 224 Confidence: 98.0% Identity: 17% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: BadF/BadG/BcrA/BcrD-like Phyre2 PDB 3h1q chain B Region: 149 - 338 Aligned: 143 Modelled: 147 Confidence: 97.9% Identity: 17% PDB header:structural protein Chain: B: PDB Molecule:ethanolamine utilization protein eutj; PDBTitle: crystal structure of ethanolamine utilization protein eutj from2 carboxydothermus hydrogenoformans Phyre2 PDB 3i8b chain A Region: 169 - 369 Aligned: 178 Modelled: 201 Confidence: 97.7% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:xylulose kinase; PDBTitle: the crystal structure of xylulose kinase from2 bifidobacterium adolescentis Phyre2 PDB 3en9 chain B Region: 2 - 317 Aligned: 257 Modelled: 282 Confidence: 97.7% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:o-sialoglycoprotein endopeptidase/protein kinase; PDBTitle: structure of the methanococcus jannaschii kae1-bud32 fusion2 protein Phyre2 PDB 2p3r chain A domain 2 Region: 260 - 369 Aligned: 100 Modelled: 110 Confidence: 97.4% Identity: 22% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: Glycerol kinase Phyre2 PDB 1glb chain G Region: 260 - 369 Aligned: 100 Modelled: 110 Confidence: 97.4% Identity: 23% PDB header:phosphotransferase Chain: G: PDB Molecule:glycerol kinase; PDBTitle: structure of the regulatory complex of escherichia coli iiiglc with2 glycerol kinase Phyre2 PDB 3gbt chain A Region: 260 - 369 Aligned: 100 Modelled: 109 Confidence: 97.3% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:gluconate kinase; PDBTitle: crystal structure of gluconate kinase from lactobacillus acidophilus Phyre2 PDB 3gg4 chain B Region: 191 - 338 Aligned: 136 Modelled: 148 Confidence: 97.2% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:glycerol kinase; PDBTitle: the crystal structure of glycerol kinase from yersinia2 pseudotuberculosis Phyre2 PDB 3hz6 chain A Region: 260 - 347 Aligned: 83 Modelled: 88 Confidence: 97.1% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:xylulokinase; PDBTitle: crystal structure of xylulokinase from chromobacterium violaceum Phyre2 PDB 3flc chain X Region: 260 - 369 Aligned: 100 Modelled: 110 Confidence: 97.1% Identity: 22% PDB header:transferase Chain: X: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of the his-tagged h232r mutant of glycerol kinase2 from enterococcus casseliflavus with glycerol Phyre2 PDB 3ezw chain D Region: 259 - 339 Aligned: 75 Modelled: 81 Confidence: 97.1% Identity: 25% PDB header:transferase Chain: D: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of a hyperactive escherichia coli glycerol kinase2 mutant gly230 --> asp obtained using microfluidic crystallization3 devices Phyre2 PDB 1e4f chain T domain 2 Region: 159 - 318 Aligned: 146 Modelled: 147 Confidence: 97.0% Identity: 13% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: Actin/HSP70 Phyre2 PDB 3ifr chain B Region: 259 - 338 Aligned: 77 Modelled: 80 Confidence: 97.0% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:carbohydrate kinase, fggy; PDBTitle: the crystal structure of xylulose kinase from rhodospirillum rubrum Phyre2 PDB 2zf5 chain O Region: 262 - 369 Aligned: 98 Modelled: 108 Confidence: 97.0% Identity: 20% PDB header:transferase Chain: O: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of highly thermostable glycerol kinase from a2 hyperthermophilic archaeon Phyre2 PDB 2d4w chain A Region: 260 - 369 Aligned: 100 Modelled: 110 Confidence: 96.9% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of glycerol kinase from cellulomonas sp.2 nt3060 Phyre2 PDB 1r59 chain O domain 2 Region: 259 - 369 Aligned: 101 Modelled: 111 Confidence: 96.9% Identity: 22% Fold: Ribonuclease H-like motif Superfamily: Actin-like ATPase domain Family: Glycerol kinase Phyre2 1 c3cqyA_ 2 c3qbwA_ 3 c3enoB_ 4 c2ivoC_ 5 d1huxa_ 6 c3h1qB_ 7 c3i8bA_ 8 c3en9B_ 9 d2p3ra2 10 c1glbG_ 11 c3gbtA_ 12 c3gg4B_ 13 c3hz6A_ 14 c3flcX_ 15 c3ezwD_ 16 d1e4ft2 17 c3ifrB_ 18 c2zf5O_ 19 c2d4wA_ 20 d1r59o2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3cqyA_ 100.0 48 PDB header:transferase Chain: A: PDB Molecule:anhydro-n-acetylmuramic acid kinase; PDBTitle: crystal structure of a functionally unknown protein (so_1313) from2 shewanella oneidensis mr-1 2 c3qbwA_ 100.0 49 PDB header:transferase Chain: A: PDB Molecule:anhydro-n-acetylmuramic acid kinase; PDBTitle: crystal structure of pseudomonas aeruginosa 1,6-anhydro-n-2 actetylmuramic acid kinase (anmk) bound to adenosine diphosphate 3 c3enoB_ 99.2 21 PDB header:hydrolase/unknown function Chain: B: PDB Molecule:putative o-sialoglycoprotein endopeptidase; PDBTitle: crystal structure of pyrococcus furiosus pcc1 in complex2 with thermoplasma acidophilum kae1 4 c2ivoC_ 98.2 17 PDB header:hydrolase Chain: C: PDB Molecule:up1; PDBTitle: structure of up1 protein 5 d1huxa_ 98.0 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like 6 c3h1qB_ 97.9 17 PDB header:structural protein Chain: B: PDB Molecule:ethanolamine utilization protein eutj; PDBTitle: crystal structure of ethanolamine utilization protein eutj from2 carboxydothermus hydrogenoformans 7 c3i8bA_ 97.7 17 PDB header:transferase Chain: A: PDB Molecule:xylulose kinase; PDBTitle: the crystal structure of xylulose kinase from2 bifidobacterium adolescentis 8 c3en9B_ 97.7 17 PDB header:hydrolase Chain: B: PDB Molecule:o-sialoglycoprotein endopeptidase/protein kinase; PDBTitle: structure of the methanococcus jannaschii kae1-bud32 fusion2 protein 9 d2p3ra2 97.4 22 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Glycerol kinase 10 c1glbG_ 97.4 23 PDB header:phosphotransferase Chain: G: PDB Molecule:glycerol kinase; PDBTitle: structure of the regulatory complex of escherichia coli iiiglc with2 glycerol kinase 11 c3gbtA_ 97.3 13 PDB header:transferase Chain: A: PDB Molecule:gluconate kinase; PDBTitle: crystal structure of gluconate kinase from lactobacillus acidophilus 12 c3gg4B_ 97.2 17 PDB header:transferase Chain: B: PDB Molecule:glycerol kinase; PDBTitle: the crystal structure of glycerol kinase from yersinia2 pseudotuberculosis 13 c3hz6A_ 97.1 18 PDB header:transferase Chain: A: PDB Molecule:xylulokinase; PDBTitle: crystal structure of xylulokinase from chromobacterium violaceum 14 c3flcX_ 97.1 22 PDB header:transferase Chain: X: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of the his-tagged h232r mutant of glycerol kinase2 from enterococcus casseliflavus with glycerol 15 c3ezwD_ 97.1 25 PDB header:transferase Chain: D: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of a hyperactive escherichia coli glycerol kinase2 mutant gly230 --> asp obtained using microfluidic crystallization3 devices 16 d1e4ft2 97.0 13 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 17 c3ifrB_ 97.0 19 PDB header:transferase Chain: B: PDB Molecule:carbohydrate kinase, fggy; PDBTitle: the crystal structure of xylulose kinase from rhodospirillum rubrum 18 c2zf5O_ 97.0 20 PDB header:transferase Chain: O: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of highly thermostable glycerol kinase from a2 hyperthermophilic archaeon 19 c2d4wA_ 96.9 23 PDB header:transferase Chain: A: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of glycerol kinase from cellulomonas sp.2 nt3060 20 d1r59o2 96.9 22 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Glycerol kinase 21 c2cgkB_ not modelled 96.8 19 PDB header:transferase Chain: B: PDB Molecule:l-rhamnulose kinase; PDBTitle: crystal structure of l-rhamnulose kinase from escherichia2 coli in an open uncomplexed conformation. 22 c2nlxA_ not modelled 96.8 22 PDB header:transferase Chain: A: PDB Molecule:xylulose kinase; PDBTitle: crystal structure of the apo e. coli xylulose kinase 23 c1mwmA_ not modelled 96.8 12 PDB header:structural protein Chain: A: PDB Molecule:parm; PDBTitle: parm from plasmid r1 adp form 24 c2dpnB_ not modelled 96.7 22 PDB header:transferase Chain: B: PDB Molecule:glycerol kinase; PDBTitle: crystal structure of the glycerol kinase from thermus2 thermophilus hb8 25 c1xupO_ not modelled 96.5 22 PDB header:transferase Chain: O: PDB Molecule:glycerol kinase; PDBTitle: enterococcus casseliflavus glycerol kinase complexed with glycerol 26 c3g25B_ not modelled 96.5 18 PDB header:transferase Chain: B: PDB Molecule:glycerol kinase; PDBTitle: 1.9 angstrom crystal structure of glycerol kinase (glpk) from2 staphylococcus aureus in complex with glycerol. 27 c3jvpA_ not modelled 96.4 26 PDB header:transferase Chain: A: PDB Molecule:ribulokinase; PDBTitle: crystal structure of ribulokinase from bacillus halodurans 28 c3h6eB_ not modelled 96.2 23 PDB header:transferase Chain: B: PDB Molecule:carbohydrate kinase, fggy; PDBTitle: the crystal structure of a carbohydrate kinase from novosphingobium2 aromaticivorans 29 d2e8aa2 not modelled 96.2 22 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 30 c2w40C_ not modelled 96.0 20 PDB header:transferase Chain: C: PDB Molecule:glycerol kinase, putative; PDBTitle: crystal structure of plasmodium falciparum glycerol kinase2 with bound glycerol 31 d1jcea2 not modelled 95.9 15 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 32 c2v7zA_ not modelled 95.9 19 PDB header:chaperone Chain: A: PDB Molecule:heat shock cognate 71 kda protein; PDBTitle: crystal structure of the 70-kda heat shock cognate protein2 from rattus norvegicus in post-atp hydrolysis state 33 d1bupa2 not modelled 95.9 19 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 34 c1hpmA_ not modelled 95.4 19 PDB header:hydrolase (acting on acid anhydrides) Chain: A: PDB Molecule:44k atpase fragment (n-terminal) of 7o kd heat- PDBTitle: how potassium affects the activity of the molecular2 chaperone hsc70. ii. potassium binds specifically in the3 atpase active site 35 c1e4gT_ not modelled 94.9 16 PDB header:bacterial cell division Chain: T: PDB Molecule:cell division protein ftsa; PDBTitle: ftsa (atp-bound form) from thermotoga maritima 36 c3iucC_ not modelled 94.6 19 PDB header:chaperone Chain: C: PDB Molecule:heat shock 70kda protein 5 (glucose-regulated PDBTitle: crystal structure of the human 70kda heat shock protein 52 (bip/grp78) atpase domain in complex with adp 37 c1dkgD_ not modelled 93.9 21 PDB header:complex (hsp24/hsp70) Chain: D: PDB Molecule:molecular chaperone dnak; PDBTitle: crystal structure of the nucleotide exchange factor grpe2 bound to the atpase domain of the molecular chaperone dnak 38 d2i7na2 not modelled 93.9 16 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Fumble-like 39 d2zgya2 not modelled 93.7 13 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 40 c1jcgA_ not modelled 93.6 19 PDB header:structural protein Chain: A: PDB Molecule:rod shape-determining protein mreb; PDBTitle: mreb from thermotoga maritima, amppnp 41 c2d0oA_ not modelled 93.4 14 PDB header:chaperone Chain: A: PDB Molecule:diol dehydratase-reactivating factor large PDBTitle: strcuture of diol dehydratase-reactivating factor complexed2 with adp and mg2+ 42 d2i7pa1 not modelled 93.3 18 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Fumble-like 43 d2ewsa1 not modelled 92.7 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Fumble-like 44 c3smpA_ not modelled 92.1 16 PDB header:transferase Chain: A: PDB Molecule:pantothenate kinase 1; PDBTitle: monoclinic crystal structure of human pantothenate kinase 1 alpha 45 c2ychA_ not modelled 91.8 22 PDB header:cell cycle Chain: A: PDB Molecule:competence protein pilm; PDBTitle: pilm-piln type iv pilus biogenesis complex 46 d1dkgd2 not modelled 91.8 23 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 47 c2v7yA_ not modelled 91.6 17 PDB header:chaperone Chain: A: PDB Molecule:chaperone protein dnak; PDBTitle: crystal structure of the molecular chaperone dnak from2 geobacillus kaustophilus hta426 in post-atp hydrolysis3 state 48 c3d2fC_ not modelled 91.1 18 PDB header:chaperone Chain: C: PDB Molecule:heat shock protein homolog sse1; PDBTitle: crystal structure of a complex of sse1p and hsp70 49 c3js6A_ not modelled 91.0 19 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized parm protein; PDBTitle: crystal structure of apo psk41 parm protein 50 c3tsuA_ not modelled 90.7 17 PDB header:transferase Chain: A: PDB Molecule:transcriptional regulatory protein; PDBTitle: crystal structure of e. coli hypf with amp-pnp and carbamoyl phosphate 51 c1sazA_ not modelled 89.2 16 PDB header:transferase Chain: A: PDB Molecule:probable butyrate kinase 2; PDBTitle: membership in the askha superfamily: enzymological2 properties and crystal structure of butyrate kinase 2 from3 thermotoga maritima 52 c2fsnB_ not modelled 86.2 20 PDB header:structural protein Chain: B: PDB Molecule:hypothetical protein ta0583; PDBTitle: crystal structure of ta0583, an archaeal actin homolog, complex with2 adp 53 c1z05A_ not modelled 86.2 15 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, rok family; PDBTitle: crystal structure of the rok family transcriptional regulator, homolog2 of e.coli mlc protein. 54 c2khoA_ not modelled 85.2 22 PDB header:chaperone Chain: A: PDB Molecule:heat shock protein 70; PDBTitle: nmr-rdc / xray structure of e. coli hsp70 (dnak) chaperone2 (1-605) complexed with adp and substrate 55 c2gupA_ not modelled 82.8 15 PDB header:transferase Chain: A: PDB Molecule:rok family protein; PDBTitle: structural genomics, the crystal structure of a rok family protein2 from streptococcus pneumoniae tigr4 in complex with sucrose 56 d2fsja1 not modelled 82.5 26 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ta0583-like 57 c2i7pA_ not modelled 82.1 18 PDB header:transferase Chain: A: PDB Molecule:pantothenate kinase 3; PDBTitle: crystal structure of human pank3 in complex with accoa 58 d1saza2 not modelled 81.4 15 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Acetokinase-like 59 c1z6rC_ not modelled 80.1 10 PDB header:transcription Chain: C: PDB Molecule:mlc protein; PDBTitle: crystal structure of mlc from escherichia coli 60 d1t6ca2 not modelled 79.0 16 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ppx/GppA phosphatase 61 c2qm1D_ not modelled 78.8 15 PDB header:transferase Chain: D: PDB Molecule:glucokinase; PDBTitle: crystal structure of glucokinase from enterococcus faecalis 62 c1qr6A_ not modelled 77.1 19 PDB header:oxidoreductase Chain: A: PDB Molecule:malic enzyme 2; PDBTitle: human mitochondrial nad(p)-dependent malic enzyme 63 c2e2pA_ not modelled 76.5 20 PDB header:transferase Chain: A: PDB Molecule:hexokinase; PDBTitle: crystal structure of sulfolobus tokodaii hexokinase in2 complex with adp 64 c3euoB_ not modelled 72.4 16 PDB header:transferase Chain: B: PDB Molecule:type iii pentaketide synthase; PDBTitle: crystal structure of a fungal type iii polyketide synthase,2 oras 65 c2gqdB_ not modelled 72.3 21 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: the crystal structure of b-ketoacyl-acp synthase ii (fabf)2 from staphylococcus aureus 66 d2gfva2 not modelled 71.6 28 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 67 d2p3ra1 not modelled 71.3 14 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Glycerol kinase 68 c3aleB_ not modelled 70.6 22 PDB header:transferase Chain: B: PDB Molecule:os07g0271500 protein; PDBTitle: a type iii polyketide synthase that produces diarylheptanoid 69 d1j3na2 not modelled 70.3 28 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 70 d1e5ma2 not modelled 70.1 28 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 71 c1tqyC_ not modelled 70.0 34 PDB header:transferase Chain: C: PDB Molecule:beta-ketoacyl synthase/acyl transferase; PDBTitle: the actinorhodin ketosynthase/chain length factor 72 d1ox0a2 not modelled 69.1 24 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 73 c2wggA_ not modelled 68.7 28 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 1; PDBTitle: crystal structure of mycobacterium tuberculosis c171q kasa2 variant with bound tlm 74 c2ebdB_ not modelled 68.5 14 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase iii2 from aquifex aeolicus vf5 75 c2gfvA_ not modelled 68.4 28 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: structure of e. coli fabf (kasii) c163q mutant 76 d2ix4a2 not modelled 67.6 21 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 77 c1o1f4_ not modelled 67.3 14 PDB header:contractile protein Chain: 4: PDB Molecule:skeletal muscle actin; PDBTitle: molecular models of averaged rigor crossbridges from2 tomograms of insect flight muscle 78 c3p4iA_ not modelled 66.7 12 PDB header:transferase Chain: A: PDB Molecule:acetate kinase; PDBTitle: crystal structure of acetate kinase from mycobacterium avium 79 c2gp6B_ not modelled 66.7 21 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 2; PDBTitle: x-ray crystal structure of mycobacterium tuberculosis beta-2 ketoacyl acyl carrier protein synthase ii (mtkasb) 80 c3e1hA_ not modelled 66.5 17 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a type iii polyketide synthase2 pksiiinc from neurospora crassa 81 c1e5mA_ not modelled 65.8 28 PDB header:condensing enzyme Chain: A: PDB Molecule:beta ketoacyl acyl carrier protein synthase ii; PDBTitle: beta ketoacyl acyl carrier protein synthase ii (kasii) from2 synechocystis sp. 82 c1oxhD_ not modelled 64.4 24 PDB header:transferase Chain: D: PDB Molecule:beta ketoacyl-acyl carrier protein synthase; PDBTitle: the crystal structure of beta-ketoacyl-[acyl carrier2 protein] synthase ii from streptococcus pneumoniae,3 triclinic form 83 c2iwyB_ not modelled 64.1 28 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase; PDBTitle: human mitochondrial beta-ketoacyl acp synthase 84 d1afwa2 not modelled 63.1 28 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 85 c2d3mA_ not modelled 62.5 14 PDB header:transferase Chain: A: PDB Molecule:pentaketide chromone synthase; PDBTitle: pentaketide chromone synthase complexed with coenzyme a 86 c2ix4B_ not modelled 62.4 21 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase; PDBTitle: arabidopsis thaliana mitochondrial beta-ketoacyl acp2 synthase hexanoic acid complex 87 d1tqya2 not modelled 62.3 34 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 88 c3hhdC_ not modelled 61.6 17 PDB header:transferase, hydrolase Chain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design. 89 d1u6ea2 not modelled 61.6 9 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 90 c1j3nB_ not modelled 61.4 28 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier protein) synthase ii; PDBTitle: crystal structure of 3-oxoacyl-(acyl-carrier protein)2 synthase ii from thermus thermophilus hb8 91 c2f9aA_ not modelled 61.1 15 PDB header:transferase Chain: A: PDB Molecule:3-hydroxy-3-methylglutaryl coenzyme a synthase 1; PDBTitle: hmg-coa synthase from brassica juncea in complex with f-244 92 c1tqyD_ not modelled 61.1 15 PDB header:transferase Chain: D: PDB Molecule:actinorhodin polyketide putative beta-ketoacyl synthase 2; PDBTitle: the actinorhodin ketosynthase/chain length factor 93 c3mdqA_ not modelled 61.0 13 PDB header:hydrolase Chain: A: PDB Molecule:exopolyphosphatase; PDBTitle: crystal structure of an exopolyphosphatase (chu_0316) from cytophaga2 hutchinsonii atcc 33406 at 1.50 a resolution 94 d1tqyb2 not modelled 60.1 15 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 95 c1ub7A_ not modelled 59.4 21 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier protein] synthase; PDBTitle: the crystal analysis of beta-keroacyl-[acyl carrier protein] synthase2 iii (fabh)from thermus thermophilus. 96 c2p0uB_ not modelled 59.1 18 PDB header:transferase Chain: B: PDB Molecule:stilbenecarboxylate synthase 2; PDBTitle: crystal structure of marchantia polymorpha stilbenecarboxylate2 synthase 2 (stcs2) 97 c3e60A_ not modelled 58.6 24 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein ] synthase ii; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase ii from bartonella henselae 98 c3o04A_ not modelled 58.6 24 PDB header:transferase Chain: A: PDB Molecule:beta-keto-acyl carrier protein synthase ii; PDBTitle: crystal structure of the beta-keto-acyl carrier protein synthase ii2 (lmo2201) from listeria monocytogenes 99 c2p9lA_ not modelled 58.1 17 PDB header:structural protein Chain: A: PDB Molecule:actin-like protein 3; PDBTitle: crystal structure of bovine arp2/3 complex 100 d1m3ka2 not modelled 57.8 13 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 101 c1tuuA_ not modelled 57.0 11 PDB header:transferase Chain: A: PDB Molecule:acetate kinase; PDBTitle: acetate kinase crystallized with atpgs 102 c2qo3A_ not modelled 56.4 24 PDB header:transferase Chain: A: PDB Molecule:eryaii erythromycin polyketide synthase modules 3 and 4; PDBTitle: crystal structure of [ks3][at3] didomain from module 3 of 6-2 deoxyerthronolide b synthase 103 c3eo3B_ not modelled 55.4 13 PDB header:isomerase, transferase Chain: B: PDB Molecule:bifunctional udp-n-acetylglucosamine 2-epimerase/n- PDBTitle: crystal structure of the n-acetylmannosamine kinase domain of human2 gne protein 104 d1nvra_ not modelled 51.3 18 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 105 d1wdkc2 not modelled 50.8 29 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 106 d1bi5a1 not modelled 50.4 16 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 107 d1nm1a2 not modelled 49.8 22 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 108 c1vl6C_ not modelled 49.7 23 PDB header:oxidoreductase Chain: C: PDB Molecule:malate oxidoreductase; PDBTitle: crystal structure of nad-dependent malic enzyme (tm0542) from2 thermotoga maritima at 2.61 a resolution 109 d1ulqa2 not modelled 49.0 21 Fold:Thiolase-like Superfamily:Thiolase-like Family:Thiolase-related 110 d1k8ka2 not modelled 48.8 22 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 111 d1mzja2 not modelled 48.0 26 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 112 d2aizp1 not modelled 47.0 27 Fold:Bacillus chorismate mutase-like Superfamily:OmpA-like Family:OmpA-like 113 c3il5D_ not modelled 46.8 27 PDB header:transferase Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: structure of e. faecalis fabh in complex with 2-({4-bromo-3-2 [(diethylamino)sulfonyl]benzoyl}amino)benzoic acid 114 d1ub7a2 not modelled 46.0 19 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 115 c2zf8A_ not modelled 45.6 17 PDB header:structural protein Chain: A: PDB Molecule:component of sodium-driven polar flagellar motor; PDBTitle: crystal structure of moty 116 c2ap1A_ not modelled 45.3 17 PDB header:transferase Chain: A: PDB Molecule:putative regulator protein; PDBTitle: crystal structure of the putative regulatory protein 117 d2hmva1 not modelled 44.8 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 118 d1u0ma1 not modelled 44.4 17 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 119 d2fxua2 not modelled 44.2 17 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Actin/HSP70 120 d1ub7a1 not modelled 44.1 23 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0