Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0C8J6
DateThu Jan 5 11:30:05 GMT 2012
Unique Job ID6e9c17cb9ebd3a54

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3q94B_
Top template information
PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii;
PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'
Confidence and coverage
Confidence:100.0% Coverage: 96%
273 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTE
Secondary structure 
SS confidence 
Disorder  ?????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  NLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEV
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  VDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQAREFAEATGIDSLAVAIGTAH
Secondary structure 
SS confidence 
Disorder 
??????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  GMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280....
Sequence  QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
Secondary structure 
SS confidence 
Disorder 
?
?????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3q94 chain B

3D model

Region: 2 - 284
Aligned: 273
Modelled: 273
Confidence: 100.0%
Identity: 42%
PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii;
PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'

Phyre2

PDB 1gvf chain A

3D model

Region: 2 - 284
Aligned: 272
Modelled: 283
Confidence: 100.0%
Identity: 55%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: Class II FBP aldolase

Phyre2

PDB 1rvg chain A

3D model

Region: 2 - 284
Aligned: 276
Modelled: 283
Confidence: 100.0%
Identity: 44%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: Class II FBP aldolase

Phyre2

PDB 3c52 chain B

3D model

Region: 2 - 283
Aligned: 270
Modelled: 282
Confidence: 100.0%
Identity: 36%
PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor

Phyre2

PDB 1dos chain A

3D model

Region: 1 - 283
Aligned: 283
Modelled: 283
Confidence: 100.0%
Identity: 29%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: Class II FBP aldolase

Phyre2

PDB 3elf chain A

3D model

Region: 1 - 284
Aligned: 270
Modelled: 284
Confidence: 100.0%
Identity: 28%
PDB header:lyase
Chain: A: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase

Phyre2

PDB 3qm3 chain C

3D model

Region: 1 - 284
Aligned: 281
Modelled: 284
Confidence: 100.0%
Identity: 26%
PDB header:lyase
Chain: C: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni

Phyre2

PDB 2isw chain B

3D model

Region: 2 - 284
Aligned: 255
Modelled: 266
Confidence: 100.0%
Identity: 41%
PDB header:lyase
Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase;
PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate

Phyre2

PDB 3pm6 chain B

3D model

Region: 6 - 284
Aligned: 247
Modelled: 259
Confidence: 100.0%
Identity: 30%
PDB header:lyase
Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase;
PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr

Phyre2

PDB 2fiq chain A domain 1

3D model

Region: 7 - 264
Aligned: 251
Modelled: 256
Confidence: 99.3%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: GatZ-like

Phyre2

PDB 2qjh chain H

3D model

Region: 16 - 238
Aligned: 186
Modelled: 197
Confidence: 99.1%
Identity: 17%
PDB header:lyase
Chain: H: PDB Molecule:putative aldolase mj0400;
PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate

Phyre2

PDB 2c3z chain A

3D model

Region: 2 - 237
Aligned: 202
Modelled: 215
Confidence: 98.6%
Identity: 12%
PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus

Phyre2

PDB 1thf chain D

3D model

Region: 33 - 235
Aligned: 194
Modelled: 200
Confidence: 98.6%
Identity: 14%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Histidine biosynthesis enzymes

Phyre2

PDB 3gr7 chain A

3D model

Region: 16 - 235
Aligned: 195
Modelled: 202
Confidence: 98.6%
Identity: 15%
PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form

Phyre2

PDB 2ze3 chain A

3D model

Region: 1 - 249
Aligned: 228
Modelled: 236
Confidence: 98.6%
Identity: 13%
PDB header:isomerase
Chain: A: PDB Molecule:dfa0005;
PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus

Phyre2

PDB 1ps9 chain A domain 1

3D model

Region: 28 - 235
Aligned: 180
Modelled: 191
Confidence: 98.5%
Identity: 19%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 3gnd chain C

3D model

Region: 73 - 262
Aligned: 161
Modelled: 174
Confidence: 98.4%
Identity: 18%
PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate

Phyre2

PDB 1y0e chain A

3D model

Region: 26 - 235
Aligned: 176
Modelled: 181
Confidence: 98.4%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: NanE-like

Phyre2

PDB 2h90 chain A

3D model

Region: 28 - 235
Aligned: 181
Modelled: 190
Confidence: 98.4%
Identity: 17%
PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin

Phyre2

PDB 3eoo chain L

3D model

Region: 4 - 249
Aligned: 218
Modelled: 234
Confidence: 98.3%
Identity: 15%
PDB header:lyase
Chain: L: PDB Molecule:methylisocitrate lyase;
PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei

Phyre2
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c3q94B_
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d1gvfa_
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d1rvga_
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c3c52B_
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d1dosa_
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c3elfA_
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c3qm3C_
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c2iswB_
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c3pm6B_
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d2fiqa1
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c2qjhH_
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c2c3zA_
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d1thfd_
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c3gr7A_
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c2ze3A_
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d1ps9a1
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c3gndC_
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d1y0ea_
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c2h90A_
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c3eooL_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3q94B_
100.0 42 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii;
PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'
2d1gvfa_
100.0 55 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
3d1rvga_
100.0 44 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
4c3c52B_
100.0 36 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor
5d1dosa_
100.0 29 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
6c3elfA_
100.0 28 PDB header:lyase
Chain: A: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase
7c3qm3C_
100.0 26 PDB header:lyase
Chain: C: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni
8c2iswB_
100.0 41 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase;
PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate
9c3pm6B_
100.0 30 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase;
PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr
10d2fiqa1
99.3 18 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:GatZ-like
11c2qjhH_
99.1 17 PDB header:lyase
Chain: H: PDB Molecule:putative aldolase mj0400;
PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate
12c2c3zA_
98.6 12 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
13d1thfd_
98.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
14c3gr7A_
98.6 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
15c2ze3A_
98.6 13 PDB header:isomerase
Chain: A: PDB Molecule:dfa0005;
PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus
16d1ps9a1
98.5 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
17c3gndC_
98.4 18 PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
18d1y0ea_
98.4 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
19c2h90A_
98.4 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
20c3eooL_
98.3 15 PDB header:lyase
Chain: L: PDB Molecule:methylisocitrate lyase;
PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei
21c3b8iF_
not modelled 98.3 16 PDB header:lyase
Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase;
PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+.
22d1j5ta_
not modelled 98.3 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
23c1ps9A_
not modelled 98.2 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
24c3ih1A_
not modelled 98.2 12 PDB header:lyase
Chain: A: PDB Molecule:methylisocitrate lyase;
PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis
25c3hf3A_
not modelled 98.2 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
26c3qjaA_
not modelled 98.2 15 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
27d1muma_
not modelled 98.2 13 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like
28c3kruC_
not modelled 98.2 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
29d1a53a_
not modelled 98.1 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
30d1h5ya_
not modelled 98.1 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
31c3igsB_
not modelled 98.1 11 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
32d1ujqa_
not modelled 98.1 15 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like
33d1xcfa_
not modelled 98.1 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
34d1i4na_
not modelled 98.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
35d1z41a1
not modelled 97.9 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
36d1tqxa_
not modelled 97.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
37d1yxya1
not modelled 97.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
38c2qiwA_
not modelled 97.8 15 PDB header:transferase
Chain: A: PDB Molecule:pep phosphonomutase;
PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution
39c3k30B_
not modelled 97.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex
40c3bo9B_
not modelled 97.8 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
41d1vyra_
not modelled 97.8 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
42d1ka9f_
not modelled 97.8 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
43d1rd5a_
not modelled 97.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
44c3q58A_
not modelled 97.8 14 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
45c2z6jB_
not modelled 97.7 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
46c3l5aA_
not modelled 97.7 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus
47c2gq8A_
not modelled 97.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, fmn-binding;
PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone
48d1h1ya_
not modelled 97.7 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
49d1qopa_
not modelled 97.7 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
50d1wbha1
not modelled 97.6 10 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
51c3tdmD_
not modelled 97.5 16 PDB header:de novo protein
Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel
PDBTitle: computationally designed tim-barrel protein, halfflr
52c2cw6B_
not modelled 97.4 14 PDB header:lyase
Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial;
PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
53d1vhca_
not modelled 97.4 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
54d1piia2
not modelled 97.3 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
55c1djnB_
not modelled 97.3 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
56d1xm3a_
not modelled 97.3 13 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
57c3fa4D_
not modelled 97.3 17 PDB header:lyase
Chain: D: PDB Molecule:2,3-dimethylmalate lyase;
PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form
58d1ojxa_
not modelled 97.2 19 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
59d1m3ua_
not modelled 97.2 16 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Ketopantoate hydroxymethyltransferase PanB
60c1zlpA_
not modelled 97.2 13 PDB header:lyase
Chain: A: PDB Molecule:petal death protein;
PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct
61d1s2wa_
not modelled 97.2 14 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like
62c2y85D_
not modelled 97.2 14 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
63c3lyeA_
not modelled 97.2 14 PDB header:hydrolase
Chain: A: PDB Molecule:oxaloacetate acetyl hydrolase;
PDBTitle: crystal structure of oxaloacetate acetylhydrolase
64d1gwja_
not modelled 97.2 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
65c3thaB_
not modelled 97.2 14 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
66c2w6rA_
not modelled 97.2 11 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
67c2gjlA_
not modelled 97.1 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
68d1wa3a1
not modelled 97.1 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
69c2ftpA_
not modelled 97.1 18 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa
70d1mxsa_
not modelled 97.0 10 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
71d1geqa_
not modelled 97.0 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
72c3dxiB_
not modelled 97.0 19 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative aldolase;
PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus
73c3ivuB_
not modelled 97.0 17 PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og
74c1ydoC_
not modelled 96.9 15 PDB header:lyase
Chain: C: PDB Molecule:hmg-coa lyase;
PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181.
75c3daqB_
not modelled 96.8 20 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus
76d1wv2a_
not modelled 96.8 19 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
77c3ajxA_
not modelled 96.8 16 PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase
78d1vzwa1
not modelled 96.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
79c2nx9B_
not modelled 96.7 16 PDB header:lyase
Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha;
PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae
80c3lerA_
not modelled 96.6 19 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 campylobacter jejuni subsp. jejuni nctc 11168
81c3qc3B_
not modelled 96.6 11 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
82c2zrvC_
not modelled 96.6 14 PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.
83c3pueA_
not modelled 96.5 19 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution
84c3f4wA_
not modelled 96.5 16 PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium
85c2rfgB_
not modelled 96.5 13 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution
86c1ydnA_
not modelled 96.5 14 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35.
87d1rpxa_
not modelled 96.4 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
88c2hjpA_
not modelled 96.4 17 PDB header:hydrolase
Chain: A: PDB Molecule:phosphonopyruvate hydrolase;
PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++
89c3inpA_
not modelled 96.4 15 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
90d1xkya1
not modelled 96.3 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
91c3bi8A_
not modelled 96.3 15 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum
92d2flia1
not modelled 96.3 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
93c2a7nA_
not modelled 96.3 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase
94d1vjia_
not modelled 96.2 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
95d1djqa1
not modelled 96.2 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
96d1vc4a_
not modelled 96.1 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
97d1tb3a1
not modelled 96.1 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
98c3gkaB_
not modelled 96.1 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:n-ethylmaleimide reductase;
PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei
99d2a6na1
not modelled 96.1 18 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
100c3labA_
not modelled 96.1 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
101d1p0ka_
not modelled 96.0 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
102d1p4ca_
not modelled 96.0 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
103c3noeA_
not modelled 96.0 19 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa
104d1xi3a_
not modelled 96.0 21 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
105d1icpa_
not modelled 95.9 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
106d1tqja_
not modelled 95.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
107c2vc6A_
not modelled 95.8 12 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: structure of mosa from s. meliloti with pyruvate bound
108c3fluD_
not modelled 95.8 14 PDB header:lyase
Chain: D: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis
109d1qo2a_
not modelled 95.8 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
110d2mnra1
not modelled 95.7 21 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:D-glucarate dehydratase-like
111d1xxxa1
not modelled 95.7 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
112d1goxa_
not modelled 95.7 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
113d1o5ka_
not modelled 95.7 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
114d1w0ma_
not modelled 95.7 20 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
115c3g0sA_
not modelled 95.7 15 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2
116d1oyaa_
not modelled 95.7 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
117c2r8wB_
not modelled 95.6 20 PDB header:lyase
Chain: B: PDB Molecule:agr_c_1641p;
PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58
118c3jrkG_
not modelled 95.6 21 PDB header:lyase
Chain: G: PDB Molecule:tagatose 1,6-diphosphate aldolase 2;
PDBTitle: a putative tagatose 1,6-diphosphate aldolase from streptococcus2 pyogenes
119c3lciA_
not modelled 95.5 16 PDB header:lyase
Chain: A: PDB Molecule:n-acetylneuraminate lyase;
PDBTitle: the d-sialic acid aldolase mutant v251w
120c3n2xB_
not modelled 95.4 19 PDB header:lyase
Chain: B: PDB Molecule:uncharacterized protein yage;
PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0