Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	P	R	A	L	L	L	V	D	L	Q	N	D	F	C	A	G	G	A	L	A	V	P	E	G	D	S	T	V	D	V	A	N	R	L	I	D	W	C	Q	S	R	G	E	A	V	I	A	S	Q	D	W	H	P	A	N	H	G	S
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	A	S	Q	H	G	V	E	P	Y	T	P	G	Q	L	D	G	L	P	Q	T	F	W	P	D	H	C	V	Q	N	S	E	G	A	Q	L	H	P	L	L	H	Q	K	A	I	A	A	V	F	H	K	G	E	N	P	L	V	D	S	Y
Secondary structure
SS confidence
Disorder						?	?	?		?	?		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	A	F	F	D	N	G	R	R	Q	K	T	S	L	D	D	W	L	R	D	H	E	I	D	E	L	I	V	M	G	L	A	T	D	Y	C	V	K	F	T	V	L	D	A	L	Q	L	G	Y	K	V	N	V	I	T	D	G	C	R	G
Secondary structure
SS confidence
Disorder								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.
Sequence		V	N	I	Q	P	Q	D	S	A	H	A	F	M	E	M	S	A	A	G	A	T	L	Y	T	L	A	D	W	E	E	T	Q	G
Secondary structure
SS confidence
Disorder																																	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2h0r chain D Region: 4 - 205 Aligned: 202 Modelled: 202 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p Phyre2 PDB 2wta chain A Region: 2 - 209 Aligned: 203 Modelled: 208 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease Phyre2 PDB 1nba chain A Region: 2 - 212 Aligned: 188 Modelled: 205 Confidence: 100.0% Identity: 20% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3hu5 chain B Region: 2 - 212 Aligned: 186 Modelled: 211 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough Phyre2 PDB 2fq1 chain A Region: 2 - 211 Aligned: 181 Modelled: 195 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains Phyre2 PDB 3r2j chain C Region: 1 - 208 Aligned: 188 Modelled: 193 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate Phyre2 PDB 3irv chain A Region: 3 - 212 Aligned: 186 Modelled: 202 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a Phyre2 PDB 1nf9 chain A Region: 2 - 210 Aligned: 178 Modelled: 188 Confidence: 100.0% Identity: 21% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3oqp chain A Region: 2 - 212 Aligned: 172 Modelled: 179 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 1j2r chain A Region: 2 - 212 Aligned: 182 Modelled: 191 Confidence: 100.0% Identity: 22% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3ot4 chain F Region: 2 - 210 Aligned: 181 Modelled: 190 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf Phyre2 PDB 1im5 chain A Region: 2 - 204 Aligned: 178 Modelled: 182 Confidence: 100.0% Identity: 42% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3oqp chain B Region: 2 - 212 Aligned: 172 Modelled: 179 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3kl2 chain K Region: 2 - 212 Aligned: 189 Modelled: 204 Confidence: 100.0% Identity: 21% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis Phyre2 PDB 3gbc chain A Region: 1 - 205 Aligned: 182 Modelled: 190 Confidence: 100.0% Identity: 35% PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide Phyre2 PDB 3hb7 chain G Region: 2 - 212 Aligned: 180 Modelled: 189 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a Phyre2 PDB 3eef chain A Region: 2 - 208 Aligned: 171 Modelled: 187 Confidence: 100.0% Identity: 31% PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum Phyre2 PDB 3mcw chain A Region: 2 - 213 Aligned: 173 Modelled: 180 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution Phyre2 PDB 3o93 chain A Region: 3 - 206 Aligned: 173 Modelled: 182 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes Phyre2 PDB 3lqy chain A Region: 2 - 209 Aligned: 168 Modelled: 176 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica Phyre2 1 c2h0rD_ 2 c2wtaA_ 3 d1nbaa_ 4 c3hu5B_ 5 c2fq1A_ 6 c3r2jC_ 7 c3irvA_ 8 d1nf9a_ 9 c3oqpA_ 10 d1j2ra_ 11 c3ot4F_ 12 d1im5a_ 13 c3oqpB_ 14 c3kl2K_ 15 c3gbcA_ 16 c3hb7G_ 17 c3eefA_ 18 c3mcwA_ 19 c3o93A_ 20 c3lqyA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2h0rD_ 100.0 34 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 2 c2wtaA_ 100.0 37 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease 3 d1nbaa_ 100.0 20 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 4 c3hu5B_ 100.0 28 PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough 5 c2fq1A_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains 6 c3r2jC_ 100.0 37 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate 7 c3irvA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a 8 d1nf9a_ 100.0 21 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 9 c3oqpA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 10 d1j2ra_ 100.0 22 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 11 c3ot4F_ 100.0 23 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 12 d1im5a_ 100.0 42 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 13 c3oqpB_ 100.0 30 PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 14 c3kl2K_ 100.0 21 PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis 15 c3gbcA_ 100.0 35 PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide 16 c3hb7G_ 100.0 23 PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a 17 c3eefA_ 100.0 31 PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum 18 c3mcwA_ 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution 19 c3o93A_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes 20 c3lqyA_ 100.0 26 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica 21 c2a67C_ not modelled 100.0 24 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein 22 c1yzvA_ not modelled 100.0 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: hypothetical protein from trypanosoma cruzi 23 d1yaca_ not modelled 100.0 26 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 24 c2b34C_ not modelled 100.0 25 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 25 d1x9ga_ not modelled 100.0 24 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 26 d1cmwa2 not modelled 83.4 19 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 27 d1tfra2 not modelled 67.4 14 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 28 c2ihnA_ not modelled 66.9 12 PDB header:hydrolase/dna Chain: A: PDB Molecule:ribonuclease h; PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate 29 d1tyza_ not modelled 63.6 16 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 30 d1xdpa3 not modelled 55.7 18 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 31 d1xp8a1 not modelled 54.0 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 32 c1xdoB_ not modelled 53.7 18 PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase 33 d1a9xa3 not modelled 53.5 17 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 34 d1f2da_ not modelled 50.6 14 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 35 c1cmwA_ not modelled 47.0 21 PDB header:transferase Chain: A: PDB Molecule:protein (dna polymerase i); PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain 36 c3fkjA_ not modelled 45.1 17 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerases; PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution 37 d1vp8a_ not modelled 39.4 21 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 38 c2b4qB_ not modelled 38.9 17 PDB header:oxidoreductase Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl- PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex 39 d1oi7a1 not modelled 38.7 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 40 c3euaD_ not modelled 38.4 10 PDB header:isomerase Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase; PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution 41 d1xu9a_ not modelled 38.2 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 42 d1qsga_ not modelled 38.0 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 43 d2dt5a1 not modelled 36.9 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Transcriptional repressor Rex, N-terminal domain 44 c1xp8A_ not modelled 36.1 13 PDB header:dna binding protein Chain: A: PDB Molecule:reca protein; PDBTitle: "deinococcus radiodurans reca in complex with atp-gamma-s" 45 c2nm0B_ not modelled 35.5 17 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2) 46 c2f06B_ not modelled 35.3 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of protein bt0572 from bacteroides thetaiotaomicron 47 c1x1qA_ not modelled 34.3 14 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8 48 d1nhpa2 not modelled 33.5 25 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 49 d1gz6a_ not modelled 32.9 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 50 d2bd0a1 not modelled 32.2 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 51 c3toxG_ not modelled 31.9 21 PDB header:oxidoreductase Chain: G: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021 52 c3nugA_ not modelled 31.6 23 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase; PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti 53 c2recB_ not modelled 30.1 8 PDB header:helicase PDB COMPND: 54 d2ae2a_ not modelled 28.6 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 55 c3g8rA_ not modelled 27.9 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 56 c2ptgA_ not modelled 27.8 19 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: crystal structure of eimeria tenella enoyl reductase 57 d1ooea_ not modelled 27.8 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 58 d2bs2a2 not modelled 27.7 21 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:Succinate dehydrogenase/fumarate reductase flavoprotein N-terminal domain 59 d1qopb_ not modelled 26.7 16 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 60 d1duvg2 not modelled 26.5 11 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 61 d1pv8a_ not modelled 26.3 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 62 d1ae1a_ not modelled 25.9 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 63 c3v2hB_ not modelled 25.9 7 PDB header:oxidoreductase Chain: B: PDB Molecule:d-beta-hydroxybutyrate dehydrogenase; PDBTitle: the crystal structure of d-beta-hydroxybutyrate dehydrogenase from2 sinorhizobium meliloti 64 c3rd5A_ not modelled 24.9 13 PDB header:oxidoreductase Chain: A: PDB Molecule:mypaa.01249.c; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium paratuberculosis 65 c3i1jB_ not modelled 24.7 17 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short chain PDBTitle: structure of a putative short chain dehydrogenase from2 pseudomonas syringae 66 d1o5wa1 not modelled 24.7 19 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 67 c2dy0A_ not modelled 24.5 27 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 68 c3d3kD_ not modelled 24.2 5 PDB header:protein binding Chain: D: PDB Molecule:enhancer of mrna-decapping protein 3; PDBTitle: crystal structure of human edc3p 69 d1mg5a_ not modelled 23.5 22 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 70 d1v8za1 not modelled 23.4 17 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 71 d1dxha2 not modelled 23.2 18 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 72 c2p68A_ not modelled 23.2 13 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5 73 c3grkE_ not modelled 23.0 13 PDB header:oxidoreductase Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh); PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis 74 d1ulsa_ not modelled 22.7 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 75 c2cfcB_ not modelled 22.6 20 PDB header:oxidoreductase Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase; PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases 76 c3rkrC_ not modelled 22.3 17 PDB header:oxidoreductase Chain: C: PDB Molecule:short chain oxidoreductase; PDBTitle: crystal structure of a metagenomic short-chain oxidoreductase (sdr) in2 complex with nadp 77 c1vlvA_ not modelled 22.0 6 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution 78 c2vyeA_ not modelled 22.0 13 PDB header:hydrolase Chain: A: PDB Molecule:replicative dna helicase; PDBTitle: crystal structure of the dnac-ssdna complex 79 d1c0pa1 not modelled 21.8 21 Fold:Nucleotide-binding domain Superfamily:Nucleotide-binding domain Family:D-aminoacid oxidase, N-terminal domain 80 d1ulua_ not modelled 21.4 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 81 d2pd4a1 not modelled 21.3 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 82 c3edmD_ not modelled 21.2 17 PDB header:oxidoreductase Chain: D: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase from agrobacterium2 tumefaciens 83 d1pr9a_ not modelled 21.1 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 84 c2ntnB_ not modelled 21.1 20 PDB header:oxidoreductase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of maba-c60v/g139a/s144l 85 c3m1aF_ not modelled 21.1 17 PDB header:oxidoreductase Chain: F: PDB Molecule:putative dehydrogenase; PDBTitle: the crystal structure of a short-chain dehydrogenase from2 streptomyces avermitilis to 2a 86 c2nwqA_ not modelled 20.7 17 PDB header:oxidoreductase Chain: A: PDB Molecule:probable short-chain dehydrogenase; PDBTitle: short chain dehydrogenase from pseudomonas aeruginosa 87 d1xsea_ not modelled 20.6 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 88 d2a4ka1 not modelled 20.6 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 89 c3ek2D_ not modelled 20.1 10 PDB header:oxidoreductase Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh); PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b 90 c2ha8A_ not modelled 20.1 6 PDB header:rna binding protein Chain: A: PDB Molecule:tar (hiv-1) rna loop binding protein; PDBTitle: methyltransferase domain of human tar (hiv-1) rna binding2 protein 1 91 c3l77A_ not modelled 19.8 10 PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain alcohol dehydrogenase; PDBTitle: x-ray structure alcohol dehydrogenase from archaeon thermococcus2 sibiricus complexed with 5-hydroxy-nadp 92 d1k2wa_ not modelled 19.8 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 93 c2ehdB_ not modelled 19.6 17 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short-chain dehydrogenase/reductase family; PDBTitle: crystal structure analysis of oxidoreductase 94 d1ubea1 not modelled 19.4 6 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 95 c2w37A_ not modelled 19.3 14 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic; PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii 96 c2pd6D_ not modelled 19.2 12 PDB header:oxidoreductase Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8; PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8 97 d1xq1a_ not modelled 19.2 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 98 d2o8ra3 not modelled 19.1 17 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 99 c3g68A_ not modelled 19.1 18 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerase; PDBTitle: crystal structure of a putative phosphosugar isomerase (cd3275) from2 clostridium difficile 630 at 1.80 a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0