Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	S	K	V	V	V	P	A	Q	G	K	K	I	T	L	Q	N	G	K	L	N	V	P	E	N	P	I	I	P	Y	I	E	G	D	G	I	G	V	D	V	T	P	A	M	L	K	V	V	D	A	A	V	E	K	A	Y	K	G	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?						?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	K	I	S	W	M	E	I	Y	T	G	E	K	S	T	Q	V	Y	G	Q	D	V	W	L	P	A	E	T	L	D	L	I	R	E	Y	R	V	A	I	K	G	P	L	T	T	P	V	G	G	G	I	R	S	L	N	V	A	L	R	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	L	D	L	Y	I	C	L	R	P	V	R	Y	Y	Q	G	T	P	S	P	V	K	H	P	E	L	T	D	M	V	I	F	R	E	N	S	E	D	I	Y	A	G	I	E	W	K	A	D	S	A	D	A	E	K	V	I	K	F	L	R
Secondary structure
SS confidence
Disorder																																															?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	E	M	G	V	K	K	I	R	F	P	E	H	C	G	I	G	I	K	P	C	S	E	E	G	T	K	R	L	V	R	A	A	I	E	Y	A	I	A	N	D	R	D	S	V	T	L	V	H	K	G	N	I	M	K	F	T	E	G	A
Secondary structure
SS confidence
Disorder			?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		F	K	D	W	G	Y	Q	L	A	R	E	E	F	G	G	E	L	I	D	G	G	P	W	L	K	V	K	N	P	N	T	G	K	E	I	V	I	K	D	V	I	A	D	A	F	L	Q	Q	I	L	L	R	P	A	E	Y	D	V	I	A
Secondary structure
SS confidence
Disorder																					?			?	?	?	?	?	?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		C	M	N	L	N	G	D	Y	I	S	D	A	L	A	A	Q	V	G	G	I	G	I	A	P	G	A	N	I	G	D	E	C	A	L	F	E	A	T	H	G	T	A	P	K	Y	A	G	Q	D	K	V	N	P	G	S	I	I	L	S	A
Secondary structure
SS confidence
Disorder																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
Sequence		E	M	M	L	R	H	M	G	W	T	E	A	A	D	L	I	V	K	G	M	E	G	A	I	N	A	K	T	V	T	Y	D	F	E	R	L	M	D	G	A	K	L	L	K	C	S	E	F	G	D	A	I	I	E	N	M
Secondary structure
SS confidence
Disorder																																						?	?	?	?																?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1pb1 chain A Region: 1 - 416 Aligned: 416 Modelled: 416 Confidence: 100.0% Identity: 100% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 2d4v chain D Region: 5 - 416 Aligned: 392 Modelled: 392 Confidence: 100.0% Identity: 66% PDB header:oxidoreductase Chain: D: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of nad dependent isocitrate dehydrogenase2 from acidithiobacillus thiooxidans Phyre2 PDB 1hqs chain A Region: 9 - 416 Aligned: 405 Modelled: 408 Confidence: 100.0% Identity: 69% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 2e0c chain A Region: 5 - 416 Aligned: 373 Modelled: 392 Confidence: 100.0% Identity: 53% PDB header:oxidoreductase Chain: A: PDB Molecule:409aa long hypothetical nadp-dependent isocitrate PDBTitle: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii2 strain7 at 2.0 a resolution Phyre2 PDB 1tyo chain A Region: 2 - 416 Aligned: 389 Modelled: 395 Confidence: 100.0% Identity: 52% PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in2 complex with etheno-nadp Phyre2 PDB 2d1c chain B Region: 10 - 416 Aligned: 344 Modelled: 364 Confidence: 100.0% Identity: 40% PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of tt0538 protein from thermus thermophilus hb8 Phyre2 PDB 1cm7 chain A Region: 24 - 416 Aligned: 344 Modelled: 354 Confidence: 100.0% Identity: 27% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 3fmx chain X Region: 27 - 416 Aligned: 340 Modelled: 351 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase; PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh Phyre2 PDB 1v53 chain A domain 1 Region: 26 - 416 Aligned: 342 Modelled: 351 Confidence: 100.0% Identity: 27% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1vlc chain A Region: 24 - 416 Aligned: 340 Modelled: 350 Confidence: 100.0% Identity: 31% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1cnz chain A Region: 24 - 416 Aligned: 344 Modelled: 354 Confidence: 100.0% Identity: 27% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1g2u chain A Region: 27 - 416 Aligned: 333 Modelled: 347 Confidence: 100.0% Identity: 29% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 3r8w chain C Region: 25 - 416 Aligned: 341 Modelled: 351 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: C: PDB Molecule:3-isopropylmalate dehydrogenase 2, chloroplastic; PDBTitle: structure of 3-isopropylmalate dehydrogenase isoform 2 from2 arabidopsis thaliana at 2.2 angstrom resolution Phyre2 PDB 1xac chain A Region: 27 - 416 Aligned: 333 Modelled: 347 Confidence: 100.0% Identity: 29% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1a05 chain A Region: 27 - 416 Aligned: 338 Modelled: 351 Confidence: 100.0% Identity: 28% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 2iv0 chain A Region: 4 - 416 Aligned: 404 Modelled: 410 Confidence: 100.0% Identity: 57% PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: thermal stability of isocitrate dehydrogenase from2 archaeoglobus fulgidus studied by crystal structure3 analysis and engineering of chimers Phyre2 PDB 3u1h chain A Region: 28 - 416 Aligned: 333 Modelled: 335 Confidence: 100.0% Identity: 31% PDB header:oxidoreductase Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase; PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus Phyre2 PDB 1wpw chain A Region: 27 - 416 Aligned: 326 Modelled: 347 Confidence: 100.0% Identity: 30% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1x0l chain B Region: 27 - 416 Aligned: 322 Modelled: 346 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: B: PDB Molecule:homoisocitrate dehydrogenase; PDBTitle: crystal structure of tetrameric homoisocitrate dehydrogenase from an2 extreme thermophile, thermus thermophilus Phyre2 PDB 1w0d chain A Region: 27 - 416 Aligned: 330 Modelled: 340 Confidence: 100.0% Identity: 32% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 1 d1pb1a_ 2 c2d4vD_ 3 d1hqsa_ 4 c2e0cA_ 5 c1tyoA_ 6 c2d1cB_ 7 d1cm7a_ 8 c3fmxX_ 9 d1v53a1 10 d1vlca_ 11 d1cnza_ 12 d1g2ua_ 13 c3r8wC_ 14 d1xaca_ 15 d1a05a_ 16 c2iv0A_ 17 c3u1hA_ 18 d1wpwa_ 19 c1x0lB_ 20 d1w0da_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1pb1a_ 100.0 100 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 2 c2d4vD_ 100.0 66 PDB header:oxidoreductase Chain: D: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of nad dependent isocitrate dehydrogenase2 from acidithiobacillus thiooxidans 3 d1hqsa_ 100.0 69 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 4 c2e0cA_ 100.0 53 PDB header:oxidoreductase Chain: A: PDB Molecule:409aa long hypothetical nadp-dependent isocitrate PDBTitle: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii2 strain7 at 2.0 a resolution 5 c1tyoA_ 100.0 52 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in2 complex with etheno-nadp 6 c2d1cB_ 100.0 40 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of tt0538 protein from thermus thermophilus hb8 7 d1cm7a_ 100.0 27 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 8 c3fmxX_ 100.0 29 PDB header:oxidoreductase Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase; PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh 9 d1v53a1 100.0 27 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 10 d1vlca_ 100.0 31 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 11 d1cnza_ 100.0 27 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 12 d1g2ua_ 100.0 29 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 13 c3r8wC_ 100.0 28 PDB header:oxidoreductase Chain: C: PDB Molecule:3-isopropylmalate dehydrogenase 2, chloroplastic; PDBTitle: structure of 3-isopropylmalate dehydrogenase isoform 2 from2 arabidopsis thaliana at 2.2 angstrom resolution 14 d1xaca_ 100.0 29 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 15 d1a05a_ 100.0 28 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 16 c2iv0A_ 100.0 57 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: thermal stability of isocitrate dehydrogenase from2 archaeoglobus fulgidus studied by crystal structure3 analysis and engineering of chimers 17 c3u1hA_ 100.0 31 PDB header:oxidoreductase Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase; PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus 18 d1wpwa_ 100.0 30 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 19 c1x0lB_ 100.0 36 PDB header:oxidoreductase Chain: B: PDB Molecule:homoisocitrate dehydrogenase; PDBTitle: crystal structure of tetrameric homoisocitrate dehydrogenase from an2 extreme thermophile, thermus thermophilus 20 d1w0da_ 100.0 32 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 21 c3blxL_ not modelled 100.0 35 PDB header:oxidoreductase Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2; PDBTitle: yeast isocitrate dehydrogenase (apo form) 22 c1zorB_ not modelled 100.0 25 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile thermotoga maritima 23 c3blxM_ not modelled 100.0 31 PDB header:oxidoreductase Chain: M: PDB Molecule:isocitrate dehydrogenase [nad] subunit 1; PDBTitle: yeast isocitrate dehydrogenase (apo form) 24 c3us8A_ not modelled 100.0 21 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase [nadp]; PDBTitle: crystal structure of an isocitrate dehydrogenase from sinorhizobium2 meliloti 1021 25 c2uxqB_ not modelled 100.0 20 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase native; PDBTitle: isocitrate dehydrogenase from the psychrophilic bacterium2 desulfotalea psychrophila: biochemical properties and3 crystal structure analysis 26 d1lwda_ not modelled 100.0 23 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 27 c2qfyE_ not modelled 100.0 19 PDB header:oxidoreductase Chain: E: PDB Molecule:isocitrate dehydrogenase [nadp]; PDBTitle: crystal structure of saccharomyces cerevesiae mitochondrial nadp(+)-2 dependent isocitrate dehydrogenase in complex with a-ketoglutarate 28 d1t0la_ not modelled 100.0 19 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 29 d1ptma_ not modelled 98.5 16 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like 30 d1r8ka_ not modelled 97.1 24 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like 31 d1itwa_ not modelled 96.7 16 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Monomeric isocitrate dehydrogenase 32 c2hi1A_ not modelled 96.5 31 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2; PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium. 33 c2b0tA_ not modelled 96.2 16 PDB header:oxidoreductase Chain: A: PDB Molecule:nadp isocitrate dehydrogenase; PDBTitle: structure of monomeric nadp isocitrate dehydrogenase 34 c1yxoB_ not modelled 96.1 21 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 1; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic protein pdxa2 pa0593 35 c2choA_ not modelled 72.7 15 PDB header:hydrolase Chain: A: PDB Molecule:glucosaminidase; PDBTitle: bacteroides thetaiotaomicron hexosaminidase with o-2 glcnacase activity 36 d2fpoa1 not modelled 72.3 8 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 37 c1p84E_ not modelled 64.0 26 PDB header:oxidoreductase Chain: E: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur PDBTitle: hdbt inhibited yeast cytochrome bc1 complex 38 c2fyuE_ not modelled 62.9 29 PDB header:oxidoreductase Chain: E: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit, PDBTitle: crystal structure of bovine heart mitochondrial bc1 with jg1442 inhibitor 39 d1riea_ not modelled 57.0 29 Fold:ISP domain Superfamily:ISP domain Family:Rieske iron-sulfur protein (ISP) 40 d3cx5e1 not modelled 46.9 26 Fold:ISP domain Superfamily:ISP domain Family:Rieske iron-sulfur protein (ISP) 41 d1oria_ not modelled 46.2 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 42 c1orhA_ not modelled 41.2 16 PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 1; PDBTitle: structure of the predominant protein arginine methyltransferase prmt1 43 d2r9ga1 not modelled 38.3 19 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:MgsA/YrvN C-terminal domain-like 44 c3pvsA_ not modelled 37.5 13 PDB header:recombination Chain: A: PDB Molecule:replication-associated recombination protein a; PDBTitle: structure and biochemical activities of escherichia coli mgsa 45 c2nvgA_ not modelled 35.6 32 PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit; PDBTitle: soluble domain of rieske iron sulfur protein. 46 d2esra1 not modelled 33.7 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 47 d2fhpa1 not modelled 32.0 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 48 c3b3jA_ not modelled 31.8 15 PDB header:transferase Chain: A: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: the 2.55 a crystal structure of the apo catalytic domain of2 coactivator-associated arginine methyl transferase i(carm1:28-507,3 residues 28-146 and 479-507 not ordered) 49 c1zn1L_ not modelled 31.7 44 PDB header:biosynthetic/structural protein/rna Chain: L: PDB Molecule:30s ribosomal protein s12; PDBTitle: coordinates of rrf fitted into cryo-em map of the 70s post-2 termination complex 50 c2fynO_ not modelled 31.0 32 PDB header:oxidoreductase Chain: O: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur PDBTitle: crystal structure analysis of the double mutant rhodobacter2 sphaeroides bc1 complex 51 d2fyta1 not modelled 30.7 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 52 d2fcaa1 not modelled 30.6 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TrmB-like 53 d2uubl1 not modelled 30.0 44 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 54 c2pebB_ not modelled 29.2 19 PDB header:oxidoreductase Chain: B: PDB Molecule:putative dioxygenase; PDBTitle: crystal structure of a putative dioxygenase (npun_f1925) from nostoc2 punctiforme pcc 73102 at 1.46 a resolution 55 c3fzgA_ not modelled 27.6 14 PDB header:transferase Chain: A: PDB Molecule:16s rrna methylase; PDBTitle: structure of the 16s rrna methylase arma 56 c3cesB_ not modelled 27.3 30 PDB header:rna binding protein Chain: B: PDB Molecule:trna uridine 5-carboxymethylaminomethyl modification enzyme PDBTitle: crystal structure of e.coli mnmg (gida), a highly-conserved trna2 modifying enzyme 57 d3bgea1 not modelled 26.1 13 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:MgsA/YrvN C-terminal domain-like 58 d1f3la_ not modelled 25.1 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 59 d1g6q1_ not modelled 23.4 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 60 d1yzha1 not modelled 23.4 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TrmB-like 61 c2e76D_ not modelled 23.1 21 PDB header:photosynthesis Chain: D: PDB Molecule:cytochrome b6-f complex iron-sulfur subunit; PDBTitle: crystal structure of the cytochrome b6f complex with tridecyl-2 stigmatellin (tds) from m.laminosus 62 d2qall1 not modelled 22.1 44 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 63 c3c6kC_ not modelled 21.9 12 PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine 64 c1yy3A_ not modelled 21.4 15 PDB header:isomerase Chain: A: PDB Molecule:s-adenosylmethionine:trna ribosyltransferase- PDBTitle: structure of s-adenosylmethionine:trna ribosyltransferase-2 isomerase (quea) 65 d3ctda1 not modelled 20.5 16 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:MgsA/YrvN C-terminal domain-like 66 c3p9nA_ not modelled 19.5 10 PDB header:transferase Chain: A: PDB Molecule:possible methyltransferase (methylase); PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase 67 c3ku1E_ not modelled 18.7 13 PDB header:transferase Chain: E: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine 68 d1i94l_ not modelled 18.3 44 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 69 c3pubA_ not modelled 17.6 29 PDB header:unknown function Chain: A: PDB Molecule:30kda protein; PDBTitle: crystal structure of the bombyx mori low molecular weight lipoprotein2 7 (bmlp7) 70 c2zkql_ not modelled 17.0 39 PDB header:ribosomal protein/rna Chain: L: PDB Molecule: PDBTitle: structure of a mammalian ribosomal 40s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map 71 c1s1hL_ not modelled 16.5 39 PDB header:ribosome Chain: L: PDB Molecule:40s ribosomal protein s23; PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1h,4 contains 40s subunit. the 60s ribosomal subunit is in file5 1s1i. 72 d1cyxa_ not modelled 16.2 15 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Periplasmic domain of cytochrome c oxidase subunit II 73 c1cyxA_ not modelled 16.2 15 PDB header:electron transport Chain: A: PDB Molecule:cyoa; PDBTitle: quinol oxidase (periplasmic fragment of subunit ii with2 engineered cu-a binding site)(cyoa) 74 c3ctdB_ not modelled 15.7 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative atpase, aaa family; PDBTitle: crystal structure of a putative aaa family atpase from2 prochlorococcus marinus subsp. pastoris 75 c3evzA_ not modelled 15.6 17 PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: crystal strucure of methyltransferase from pyrococcus furiosus 76 d1uira_ not modelled 15.1 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Spermidine synthase 77 c2v7eB_ not modelled 14.9 14 PDB header:transferase Chain: B: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: crystal structure of coactivator-associated arginine2 methyltransferase 1 (carm1), unliganded 78 d2p8ia1 not modelled 14.6 14 Fold:Ferredoxin-like Superfamily:DOPA-like Family:DOPA dioxygenase-like 79 d1fftb1 not modelled 14.3 15 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Periplasmic domain of cytochrome c oxidase subunit II 80 c3g05B_ not modelled 14.3 30 PDB header:rna binding protein Chain: B: PDB Molecule:trna uridine 5-carboxymethylaminomethyl modification enzyme PDBTitle: crystal structure of n-terminal domain (2-550) of e.coli mnmg 81 c2xzmL_ not modelled 14.2 33 PDB header:ribosome Chain: L: PDB Molecule:40s ribosomal protein s12; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1 82 d1i7na1 not modelled 13.5 16 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Synapsin domain 83 d1u35c1 not modelled 13.2 23 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 84 c2esrB_ not modelled 12.7 14 PDB header:transferase Chain: B: PDB Molecule:methyltransferase; PDBTitle: conserved hypothetical protein- streptococcus pyogenes 85 d1inla_ not modelled 12.0 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Spermidine synthase 86 c3e1tA_ not modelled 12.0 21 PDB header:flavoprotein Chain: A: PDB Molecule:halogenase; PDBTitle: structure and action of the myxobacterial chondrochloren2 halogenase cndh, a new variant of fad-dependent halogenases 87 d1f66c_ not modelled 11.7 14 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 88 c1f66C_ not modelled 11.7 14 PDB header:structural protein/dna Chain: C: PDB Molecule:histone h2a.z; PDBTitle: 2.6 a crystal structure of a nucleosome core particle2 containing the variant histone h2a.z 89 c3o2qB_ not modelled 11.5 14 PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72-ctd phosphopeptide2 complex 90 c2przB_ not modelled 11.4 19 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp 91 d1kx3c_ not modelled 11.4 16 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 92 c3bwbA_ not modelled 11.1 21 PDB header:transferase Chain: A: PDB Molecule:spermidine synthase; PDBTitle: crystal structure of the apo form of spermidine synthase from2 trypanosoma cruzi at 2.5 a resolution 93 d1hioa_ not modelled 10.9 16 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 94 d2o07a1 not modelled 10.9 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Spermidine synthase 95 c2pssC_ not modelled 10.9 15 PDB header:transferase Chain: C: PDB Molecule:spermidine synthase; PDBTitle: the structure of plasmodium falciparum spermidine synthase in its apo-2 form 96 d1n1jb_ not modelled 10.8 11 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 97 c3o2sB_ not modelled 10.5 14 PDB header:hydrolase Chain: B: PDB Molecule:rna polymerase ii subunit a c-terminal domain phosphatase PDBTitle: crystal structure of the human symplekin-ssu72 complex 98 d2jssa1 not modelled 10.4 15 Fold:Histone-fold Superfamily:Histone-fold Family:Nucleosome core histones 99 c3qd7X_ not modelled 10.2 19 PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized protein ydal; PDBTitle: crystal structure of ydal, a stand-alone small muts-related protein2 from escherichia coli

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0