Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	H	I	V	T	L	N	T	P	S	R	E	D	W	L	T	Q	L	A	D	V	V	T	D	P	D	E	L	L	R	L	L	N	I	D	A	E	E	K	L	L	A	G	R	S	A	K	K	L	F	A	L	R	V	P	R	S	F	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	R	M	E	K	G	N	P	D	D	P	L	L	R	Q	V	L	T	S	Q	D	E	F	V	I	A	P	G	F	S	T	D	P	L	E	E	Q	H	S	V	V	P	G	L	L	H	K	Y	H	N	R	A	L	L	L	V	K	G	G	C
Secondary structure
SS confidence
Disorder																								?					?		?	?		?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	V	N	C	R	Y	C	F	R	R	H	F	P	Y	A	E	N	Q	G	N	K	R	N	W	Q	T	A	L	E	Y	V	A	A	H	P	E	L	D	E	M	I	F	S	G	G	D	P	L	M	A	K	D	H	E	L	D	W	L	L	T
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	L	E	A	I	P	H	I	K	R	L	R	I	H	S	R	L	P	I	V	I	P	A	R	I	T	E	A	L	V	E	C	F	A	R	S	T	L	Q	I	L	L	V	N	H	I	N	H	A	N	E	V	D	E	T	F	R	Q	A	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	K	L	R	R	V	G	V	T	L	L	N	Q	S	V	L	L	R	D	V	N	D	N	A	Q	T	L	A	N	L	S	N	A	L	F	D	A	G	V	M	P	Y	Y	L	H	V	L	D	K	V	Q	G	A	A	H	F	M	V	S	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
Sequence		D	E	A	R	Q	I	M	R	E	L	L	T	L	V	S	G	Y	L	V	P	K	L	A	R	E	I	G	G	E	P	S	K	T	P	L	D	L	Q	L	R	Q	Q
Secondary structure
SS confidence
Disorder																																					?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2a5h chain C Region: 7 - 342 Aligned: 334 Modelled: 336 Confidence: 100.0% Identity: 32% PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). Phyre2 PDB 3rfa chain A Region: 12 - 329 Aligned: 282 Modelled: 302 Confidence: 99.9% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine Phyre2 PDB 1tv8 chain A Region: 110 - 315 Aligned: 196 Modelled: 206 Confidence: 99.8% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: MoCo biosynthesis proteins Phyre2 PDB 2yx0 chain A Region: 113 - 317 Aligned: 194 Modelled: 204 Confidence: 99.7% Identity: 14% PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 Phyre2 PDB 3c8f chain A Region: 101 - 286 Aligned: 179 Modelled: 186 Confidence: 99.6% Identity: 12% PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet Phyre2 PDB 3cix chain A Region: 111 - 320 Aligned: 197 Modelled: 201 Confidence: 99.6% Identity: 12% PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate Phyre2 PDB 3t7v chain A Region: 111 - 322 Aligned: 203 Modelled: 212 Confidence: 99.5% Identity: 9% PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) Phyre2 PDB 1r30 chain A Region: 111 - 320 Aligned: 200 Modelled: 206 Confidence: 99.5% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme Phyre2 PDB 1r30 chain A Region: 111 - 320 Aligned: 200 Modelled: 210 Confidence: 99.5% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Biotin synthase Phyre2 PDB 2qgq chain F Region: 124 - 329 Aligned: 201 Modelled: 206 Confidence: 99.5% Identity: 12% PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 Phyre2 PDB 1olt chain A Region: 120 - 322 Aligned: 200 Modelled: 203 Confidence: 99.4% Identity: 12% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Oxygen-independent coproporphyrinogen III oxidase HemN Phyre2 PDB 2z2u chain A Region: 120 - 274 Aligned: 143 Modelled: 155 Confidence: 99.1% Identity: 18% PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 Phyre2 PDB 3can chain A Region: 160 - 312 Aligned: 142 Modelled: 153 Confidence: 99.0% Identity: 15% PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 Phyre2 PDB 2f06 chain B Region: 208 - 313 Aligned: 105 Modelled: 106 Confidence: 92.4% Identity: 13% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of protein bt0572 from bacteroides thetaiotaomicron Phyre2 PDB 2nu7 chain B domain 1 Region: 164 - 251 Aligned: 80 Modelled: 88 Confidence: 87.0% Identity: 16% Fold: Flavodoxin-like Superfamily: Succinyl-CoA synthetase domains Family: Succinyl-CoA synthetase domains Phyre2 PDB 2rfg chain B Region: 133 - 272 Aligned: 136 Modelled: 140 Confidence: 82.2% Identity: 10% PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution Phyre2 PDB 2r8w chain B Region: 135 - 272 Aligned: 134 Modelled: 138 Confidence: 79.0% Identity: 13% PDB header:lyase Chain: B: PDB Molecule:agr_c_1641p; PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58 Phyre2 PDB 3daq chain B Region: 133 - 272 Aligned: 137 Modelled: 140 Confidence: 78.6% Identity: 10% PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus Phyre2 PDB 1f74 chain A Region: 135 - 272 Aligned: 135 Modelled: 138 Confidence: 76.3% Identity: 10% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 2vc6 chain A Region: 133 - 272 Aligned: 136 Modelled: 140 Confidence: 75.7% Identity: 11% PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound Phyre2 1 c2a5hC_ 2 c3rfaA_ 3 d1tv8a_ 4 c2yx0A_ 5 c3c8fA_ 6 c3cixA_ 7 c3t7vA_ 8 c1r30A_ 9 d1r30a_ 10 c2qgqF_ 11 d1olta_ 12 c2z2uA_ 13 c3canA_ 14 c2f06B_ 15 d2nu7b1 16 c2rfgB_ 17 c2r8wB_ 18 c3daqB_ 19 d1f74a_ 20 c2vc6A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2a5hC_ 100.0 32 PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). 2 c3rfaA_ 99.9 15 PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine 3 d1tv8a_ 99.8 15 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:MoCo biosynthesis proteins 4 c2yx0A_ 99.7 14 PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 5 c3c8fA_ 99.6 12 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet 6 c3cixA_ 99.6 12 PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate 7 c3t7vA_ 99.5 9 PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) 8 c1r30A_ 99.5 15 PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme 9 d1r30a_ 99.5 15 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Biotin synthase 10 c2qgqF_ 99.5 12 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 11 d1olta_ 99.4 12 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Oxygen-independent coproporphyrinogen III oxidase HemN 12 c2z2uA_ 99.1 18 PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 13 c3canA_ 99.0 15 PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 14 c2f06B_ 92.4 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of protein bt0572 from bacteroides thetaiotaomicron 15 d2nu7b1 87.0 16 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 16 c2rfgB_ 82.2 10 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution 17 c2r8wB_ 79.0 13 PDB header:lyase Chain: B: PDB Molecule:agr_c_1641p; PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58 18 c3daqB_ 78.6 10 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 19 d1f74a_ 76.3 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 20 c2vc6A_ 75.7 11 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound 21 c2nu9E_ not modelled 74.2 15 PDB header:ligase Chain: E: PDB Molecule:succinyl-coa synthetase beta chain; PDBTitle: c123at mutant of e. coli succinyl-coa synthetase2 orthorhombic crystal form 22 c3lerA_ not modelled 74.1 8 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 campylobacter jejuni subsp. jejuni nctc 11168 23 d1hl2a_ not modelled 73.5 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 24 c3lciA_ not modelled 73.4 13 PDB header:lyase Chain: A: PDB Molecule:n-acetylneuraminate lyase; PDBTitle: the d-sialic acid aldolase mutant v251w 25 c3na8A_ not modelled 72.5 10 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa 26 c3si9B_ not modelled 71.1 7 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae 27 c3e96B_ not modelled 70.4 10 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii 28 c3h5dD_ not modelled 70.3 13 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from drug-resistant streptococcus2 pneumoniae 29 c2yxgD_ not modelled 69.1 9 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihyrodipicolinate synthase (dapa) 30 c3fkkA_ not modelled 68.2 10 PDB header:lyase Chain: A: PDB Molecule:l-2-keto-3-deoxyarabonate dehydratase; PDBTitle: structure of l-2-keto-3-deoxyarabonate dehydratase 31 c3dz1A_ not modelled 67.7 10 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 32 c3n2xB_ not modelled 66.9 13 PDB header:lyase Chain: B: PDB Molecule:uncharacterized protein yage; PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate 33 c3eb2A_ not modelled 64.6 9 PDB header:lyase Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution 34 c3bi8A_ not modelled 63.6 13 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum 35 c2ehhE_ not modelled 63.0 11 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 36 c2kboA_ not modelled 61.7 8 PDB header:hydrolase Chain: A: PDB Molecule:dna dc->du-editing enzyme apobec-3g; PDBTitle: structure, interaction, and real-time monitoring of the2 enzymatic reaction of wild type apobec3g 37 d2hiya1 not modelled 61.1 22 Fold:SP0830-like Superfamily:SP0830-like Family:SP0830-like 38 c3pueA_ not modelled 59.5 11 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution 39 c3g0sA_ not modelled 58.8 12 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 40 c3cprB_ not modelled 57.2 15 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 41 d2a6na1 not modelled 56.4 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 42 c3ewbX_ not modelled 56.2 15 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 43 d1m1ha2 not modelled 55.6 23 Fold:Ferredoxin-like Superfamily:N-utilization substance G protein NusG, N-terminal domain Family:N-utilization substance G protein NusG, N-terminal domain 44 c2fmoA_ not modelled 55.4 17 PDB header:oxidoreductase Chain: A: PDB Molecule:5,10-methylenetetrahydrofolate reductase; PDBTitle: ala177val mutant of e. coli methylenetetrahydrofolate2 reductase 45 c3noeA_ not modelled 54.1 11 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 46 d1eucb1 not modelled 54.0 15 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 47 c2v9dB_ not modelled 49.0 12 PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12 48 c3lkeA_ not modelled 48.9 7 PDB header:lyase Chain: A: PDB Molecule:enoyl-coa hydratase; PDBTitle: crystal structure of enoyl-coa hydratase from bacillus2 halodurans 49 d1qwga_ not modelled 47.6 14 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 50 c3b4uB_ not modelled 47.2 10 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 51 c1eucB_ not modelled 46.2 19 PDB header:ligase Chain: B: PDB Molecule:succinyl-coa synthetase, beta chain; PDBTitle: crystal structure of dephosphorylated pig heart, gtp-2 specific succinyl-coa synthetase 52 c2pg8C_ not modelled 46.0 21 PDB header:ligand binding protein Chain: C: PDB Molecule:dpgc; PDBTitle: crystal structure of r254k mutanat of dpgc with bound substrate analog 53 c1zcoA_ not modelled 44.2 12 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase; PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase 54 c3fluD_ not modelled 43.7 10 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 55 d1o5ka_ not modelled 43.7 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 56 c3c52B_ not modelled 43.4 10 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor 57 c2nx9B_ not modelled 42.1 14 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 58 c3ndcB_ not modelled 41.1 23 PDB header:transferase Chain: B: PDB Molecule:precorrin-4 c(11)-methyltransferase; PDBTitle: crystal structure of precorrin-4 c11-methyltransferase from2 rhodobacter capsulatus 59 c3kwpA_ not modelled 40.6 10 PDB header:transferase Chain: A: PDB Molecule:predicted methyltransferase; PDBTitle: crystal structure of putative methyltransferase from lactobacillus2 brevis 60 c2nytB_ not modelled 40.5 13 PDB header:hydrolase Chain: B: PDB Molecule:probable c->u-editing enzyme apobec-2; PDBTitle: the apobec2 crystal structure and functional implications2 for aid 61 c2zf8A_ not modelled 40.1 11 PDB header:structural protein Chain: A: PDB Molecule:component of sodium-driven polar flagellar motor; PDBTitle: crystal structure of moty 62 c3d0cB_ not modelled 40.0 10 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 oceanobacillus iheyensis at 1.9 a resolution 63 d1va0a1 not modelled 39.9 23 Fold:Tetrapyrrole methylase Superfamily:Tetrapyrrole methylase Family:Tetrapyrrole methylase 64 d1xxxa1 not modelled 38.7 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 65 d1nvma2 not modelled 35.9 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 66 c1vs1B_ not modelled 35.8 10 PDB header:transferase Chain: B: PDB Molecule:3-deoxy-7-phosphoheptulonate synthase; PDBTitle: crystal structure of 3-deoxy-d-arabino-heptulosonate-7-2 phosphate synthase (dahp synthase) from aeropyrum pernix3 in complex with mn2+ and pep 67 d1xkya1 not modelled 35.6 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 68 c2r94B_ not modelled 35.4 10 PDB header:lyase Chain: B: PDB Molecule:2-keto-3-deoxy-(6-phospho-)gluconate aldolase; PDBTitle: crystal structure of kd(p)ga from t.tenax 69 c3rrvC_ not modelled 34.1 7 PDB header:isomerase Chain: C: PDB Molecule:enoyl-coa hydratase/isomerase; PDBTitle: crystal structure of an enoyl-coa hydratase/isomerase from2 mycobacterium paratuberculosis 70 c3nvtA_ not modelled 33.3 11 PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e 71 c2nuxB_ not modelled 32.6 12 PDB header:lyase Chain: B: PDB Molecule:2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate PDBTitle: 2-keto-3-deoxygluconate aldolase from sulfolobus acidocaldarius,2 native structure in p6522 at 2.5 a resolution 72 c1xuzA_ not modelled 32.6 16 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 73 c2higA_ not modelled 31.9 13 PDB header:transferase Chain: A: PDB Molecule:6-phospho-1-fructokinase; PDBTitle: crystal structure of phosphofructokinase apoenzyme from trypanosoma2 brucei. 74 d2deka1 not modelled 31.5 21 Fold:Tetrapyrrole methylase Superfamily:Tetrapyrrole methylase Family:Tetrapyrrole methylase 75 c2k06A_ not modelled 31.1 19 PDB header:transcription Chain: A: PDB Molecule:transcription antitermination protein nusg; PDBTitle: solution structure of the aminoterminal domain of e. coli2 nusg 76 d1g5ta_ not modelled 30.7 16 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 77 d1xx4a_ not modelled 30.5 15 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Crotonase-like 78 d1gvfa_ not modelled 30.3 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 79 c3rsiA_ not modelled 30.1 11 PDB header:isomerase Chain: A: PDB Molecule:putative enoyl-coa hydratase/isomerase; PDBTitle: the structure of a putative enoyl-coa hydratase/isomerase from2 mycobacterium abscessus atcc 19977 / dsm 44196 80 d1cc5a_ not modelled 29.6 19 Fold:Cytochrome c Superfamily:Cytochrome c Family:monodomain cytochrome c 81 c3gkbA_ not modelled 28.8 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative enoyl-coa hydratase; PDBTitle: crystal structure of a putative enoyl-coa hydratase from streptomyces2 avermitilis 82 d1rjma_ not modelled 28.6 15 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Crotonase-like 83 c2i55C_ not modelled 28.5 19 PDB header:isomerase Chain: C: PDB Molecule:phosphomannomutase; PDBTitle: complex of glucose-1,6-bisphosphate with phosphomannomutase from2 leishmania mexicana 84 d2cg4a2 not modelled 28.2 17 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain 85 c2ppyE_ not modelled 28.1 15 PDB header:lyase Chain: E: PDB Molecule:enoyl-coa hydratase; PDBTitle: crystal structure of enoyl-coa hydrates (gk_1992) from geobacillus2 kaustophilus hta426 86 c1m1gB_ not modelled 27.4 23 PDB header:transcription Chain: B: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of aquifex aeolicus n-utilization2 substance g (nusg), space group p2(1) 87 c3bh1A_ not modelled 27.4 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0371 protein dip2346; PDBTitle: crystal structure of protein dip2346 from corynebacterium diphtheriae 88 d2ex2a1 not modelled 27.3 16 Fold:beta-lactamase/transpeptidase-like Superfamily:beta-lactamase/transpeptidase-like Family:Dac-like 89 c2hmcA_ not modelled 27.1 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: the crystal structure of dihydrodipicolinate synthase dapa from2 agrobacterium tumefaciens 90 c2iswB_ not modelled 26.8 10 PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate 91 c3a3eB_ not modelled 26.8 35 PDB header:hydrolase Chain: B: PDB Molecule:penicillin-binding protein 4; PDBTitle: crystal structure of penicillin binding protein 4 (dacb)2 from haemophilus influenzae, complexed with novel beta-3 lactam (cmv) 92 c3q94B_ not modelled 26.5 8 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor' 93 c3g64A_ not modelled 26.0 7 PDB header:lyase Chain: A: PDB Molecule:putative enoyl-coa hydratase; PDBTitle: crystal structure of putative enoyl-coa hydratase from streptomyces2 coelicolor a3(2) 94 c2djwF_ not modelled 25.9 19 PDB header:unknown function Chain: F: PDB Molecule:probable transcriptional regulator, asnc family; PDBTitle: crystal structure of ttha0845 from thermus thermophilus hb8 95 c2e0kA_ not modelled 25.9 15 PDB header:transferase Chain: A: PDB Molecule:precorrin-2 c20-methyltransferase; PDBTitle: crystal structure of cbil, a methyltransferase involved in anaerobic2 vitamin b12 biosynthesis 96 c3e2vA_ not modelled 25.9 15 PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae 97 d1w3ia_ not modelled 25.5 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 98 d2ffja1 not modelled 25.5 10 Fold:AF1104-like Superfamily:AF1104-like Family:AF1104-like 99 d1q52a_ not modelled 25.4 15 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Crotonase-like 100 c3g8rA_ not modelled 25.3 16 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 101 c3fkjA_ not modelled 24.9 12 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerases; PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution 102 c2ftpA_ not modelled 24.8 13 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 103 d1i1ga2 not modelled 24.5 13 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain 104 c3h02F_ not modelled 24.4 15 PDB header:lyase Chain: F: PDB Molecule:naphthoate synthase; PDBTitle: 2.15 angstrom resolution crystal structure of naphthoate synthase from2 salmonella typhimurium. 105 d1wz8a1 not modelled 24.3 16 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Crotonase-like 106 c3r0oA_ not modelled 24.1 19 PDB header:lyase Chain: A: PDB Molecule:carnitinyl-coa dehydratase; PDBTitle: crystal structure of carnitinyl-coa hydratase from mycobacterium avium 107 d1qt1a_ not modelled 23.9 12 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 108 c2w3pB_ not modelled 23.2 15 PDB header:lyase Chain: B: PDB Molecule:benzoyl-coa-dihydrodiol lyase; PDBTitle: boxc crystal structure 109 c3tqkA_ not modelled 23.2 13 PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 110 d1mj3a_ not modelled 22.5 22 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Crotonase-like 111 d1nz8a_ not modelled 22.5 22 Fold:Ferredoxin-like Superfamily:N-utilization substance G protein NusG, N-terminal domain Family:N-utilization substance G protein NusG, N-terminal domain 112 c3hsiC_ not modelled 22.5 8 PDB header:transferase Chain: C: PDB Molecule:phosphatidylserine synthase; PDBTitle: crystal structure of phosphatidylserine synthase haemophilus2 influenzae rd kw20 113 c2iexA_ not modelled 22.0 11 PDB header:lyase Chain: A: PDB Molecule:dihydroxynapthoic acid synthetase; PDBTitle: crystal structure of dihydroxynapthoic acid synthetase (gk2873) from2 geobacillus kaustophilus hta426 114 c3ktsA_ not modelled 22.0 14 PDB header:transcriptional regulator Chain: A: PDB Molecule:glycerol uptake operon antiterminator regulatory protein; PDBTitle: crystal structure of glycerol uptake operon antiterminator regulatory2 protein from listeria monocytogenes str. 4b f2365 115 d3bexa2 not modelled 21.9 8 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:CoaX-like 116 c3bleA_ not modelled 21.1 8 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 117 c3o8nA_ not modelled 21.0 9 PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase, muscle type; PDBTitle: structure of phosphofructokinase from rabbit skeletal muscle 118 c2vzvB_ not modelled 20.5 11 PDB header:hydrolase Chain: B: PDB Molecule:exo-beta-d-glucosaminidase; PDBTitle: substrate complex of amycolatopsis orientalis exo-2 chitosanase csxa e541a with chitosan 119 d1sg4a1 not modelled 20.5 15 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Crotonase-like 120 c3sllC_ not modelled 20.4 6 PDB header:isomerase Chain: C: PDB Molecule:probable enoyl-coa hydratase/isomerase; PDBTitle: crystal structure of a probable enoyl-coa hydratase/isomerase from2 mycobacterium abscessus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0