Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		A	M	L	H	F	C	E	N	P	G	K	I	Q	S	R	A	E	L	L	K	K	M	T	G	R	E	L	K	P	H	D	R	T	V	D	V	T	I	R	R	I	R	K	H	F	E	S	T	P	D	T	P	E	I	I	A	T	I	H	G
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.
Sequence		E	G	Y	R	F	C	G	D	L	E	D
Secondary structure
SS confidence
Disorder								?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1opc chain A Region: 2 - 68 Aligned: 67 Modelled: 67 Confidence: 99.8% Identity: 34% Fold: DNA/RNA-binding 3-helical bundle Superfamily: C-terminal effector domain of the bipartite response regulators Family: PhoB-like Phyre2 PDB 2hwv chain A Region: 2 - 68 Aligned: 67 Modelled: 67 Confidence: 99.8% Identity: 31% PDB header:transcription Chain: A: PDB Molecule:dna-binding response regulator vicr; PDBTitle: crystal structure of an essential response regulator dna binding2 domain, vicrc in enterococcus faecalis, a member of the yycf3 subfamily. Phyre2 PDB 2zxj chain B Region: 2 - 67 Aligned: 66 Modelled: 66 Confidence: 99.8% Identity: 36% PDB header:transcription Chain: B: PDB Molecule:transcriptional regulatory protein walr; PDBTitle: crystal structure of yycf dna-binding domain from staphylococcus2 aureus Phyre2 PDB 2k4j chain A Region: 2 - 66 Aligned: 65 Modelled: 65 Confidence: 99.8% Identity: 23% PDB header:transcription Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: arsr dna binding domain Phyre2 PDB 2jzy chain A Region: 2 - 70 Aligned: 68 Modelled: 69 Confidence: 99.8% Identity: 21% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein pcor; PDBTitle: solution structure of c-terminal effector domain of2 putative two-component-system response regulator involved3 in copper resistance from klebsiella pneumoniae Phyre2 PDB 2hqn chain A Region: 2 - 70 Aligned: 68 Modelled: 69 Confidence: 99.8% Identity: 24% PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism Phyre2 PDB 1gxq chain A Region: 2 - 68 Aligned: 66 Modelled: 67 Confidence: 99.7% Identity: 38% Fold: DNA/RNA-binding 3-helical bundle Superfamily: C-terminal effector domain of the bipartite response regulators Family: PhoB-like Phyre2 PDB 1p2f chain A domain 1 Region: 2 - 67 Aligned: 64 Modelled: 66 Confidence: 99.7% Identity: 42% Fold: DNA/RNA-binding 3-helical bundle Superfamily: C-terminal effector domain of the bipartite response regulators Family: PhoB-like Phyre2 PDB 2oqr chain A Region: 2 - 66 Aligned: 65 Modelled: 65 Confidence: 99.7% Identity: 26% PDB header:transcription,signaling protein Chain: A: PDB Molecule:sensory transduction protein regx3; PDBTitle: the structure of the response regulator regx3 from mycobacterium2 tuberculosis Phyre2 PDB 2pmu chain D Region: 2 - 68 Aligned: 63 Modelled: 65 Confidence: 99.7% Identity: 17% PDB header:transcription regulation Chain: D: PDB Molecule:response regulator phop; PDBTitle: crystal structure of the dna-binding domain of phop Phyre2 PDB 1ys7 chain B Region: 2 - 68 Aligned: 65 Modelled: 67 Confidence: 99.7% Identity: 26% PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulatory protein prra; PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+ Phyre2 PDB 1ys7 chain A domain 1 Region: 2 - 68 Aligned: 63 Modelled: 67 Confidence: 99.7% Identity: 27% Fold: DNA/RNA-binding 3-helical bundle Superfamily: C-terminal effector domain of the bipartite response regulators Family: PhoB-like Phyre2 PDB 2hqr chain A Region: 2 - 68 Aligned: 66 Modelled: 67 Confidence: 99.7% Identity: 24% PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism Phyre2 PDB 2gwr chain A Region: 2 - 68 Aligned: 65 Modelled: 67 Confidence: 99.6% Identity: 26% PDB header:signaling protein Chain: A: PDB Molecule:dna-binding response regulator mtra; PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis Phyre2 PDB 1kgs chain A domain 1 Region: 2 - 68 Aligned: 61 Modelled: 67 Confidence: 99.6% Identity: 20% Fold: DNA/RNA-binding 3-helical bundle Superfamily: C-terminal effector domain of the bipartite response regulators Family: PhoB-like Phyre2 PDB 1p2f chain A Region: 2 - 67 Aligned: 64 Modelled: 66 Confidence: 99.6% Identity: 42% PDB header:transcription Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure analysis of response regulator drrb, a2 thermotoga maritima ompr/phob homolog Phyre2 PDB 2ff4 chain A domain 1 Region: 2 - 66 Aligned: 65 Modelled: 65 Confidence: 99.6% Identity: 12% Fold: DNA/RNA-binding 3-helical bundle Superfamily: C-terminal effector domain of the bipartite response regulators Family: PhoB-like Phyre2 PDB 3r0j chain A Region: 2 - 68 Aligned: 65 Modelled: 67 Confidence: 99.5% Identity: 17% PDB header:dna binding protein Chain: A: PDB Molecule:possible two component system response transcriptional PDBTitle: structure of phop from mycobacterium tuberculosis Phyre2 PDB 1kgs chain A Region: 2 - 68 Aligned: 61 Modelled: 67 Confidence: 99.3% Identity: 20% PDB header:dna binding protein Chain: A: PDB Molecule:dna binding response regulator d; PDBTitle: crystal structure at 1.50 a of an ompr/phob homolog from thermotoga2 maritima Phyre2 PDB 2ff4 chain B Region: 2 - 68 Aligned: 67 Modelled: 67 Confidence: 98.9% Identity: 12% PDB header:transcription Chain: B: PDB Molecule:probable regulatory protein embr; PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide Phyre2 1 d1opca_ 2 c2hwvA_ 3 c2zxjB_ 4 c2k4jA_ 5 c2jzyA_ 6 c2hqnA_ 7 d1gxqa_ 8 d1p2fa1 9 c2oqrA_ 10 c2pmuD_ 11 c1ys7B_ 12 d1ys7a1 13 c2hqrA_ 14 c2gwrA_ 15 d1kgsa1 16 c1p2fA_ 17 d2ff4a1 18 c3r0jA_ 19 c1kgsA_ 20 c2ff4B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1opca_ 99.8 34 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like 2 c2hwvA_ 99.8 31 PDB header:transcription Chain: A: PDB Molecule:dna-binding response regulator vicr; PDBTitle: crystal structure of an essential response regulator dna binding2 domain, vicrc in enterococcus faecalis, a member of the yycf3 subfamily. 3 c2zxjB_ 99.8 36 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulatory protein walr; PDBTitle: crystal structure of yycf dna-binding domain from staphylococcus2 aureus 4 c2k4jA_ 99.8 23 PDB header:transcription Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: arsr dna binding domain 5 c2jzyA_ 99.8 21 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein pcor; PDBTitle: solution structure of c-terminal effector domain of2 putative two-component-system response regulator involved3 in copper resistance from klebsiella pneumoniae 6 c2hqnA_ 99.8 24 PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism 7 d1gxqa_ 99.7 38 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like 8 d1p2fa1 99.7 42 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like 9 c2oqrA_ 99.7 26 PDB header:transcription,signaling protein Chain: A: PDB Molecule:sensory transduction protein regx3; PDBTitle: the structure of the response regulator regx3 from mycobacterium2 tuberculosis 10 c2pmuD_ 99.7 17 PDB header:transcription regulation Chain: D: PDB Molecule:response regulator phop; PDBTitle: crystal structure of the dna-binding domain of phop 11 c1ys7B_ 99.7 26 PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulatory protein prra; PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+ 12 d1ys7a1 99.7 27 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like 13 c2hqrA_ 99.7 24 PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism 14 c2gwrA_ 99.6 26 PDB header:signaling protein Chain: A: PDB Molecule:dna-binding response regulator mtra; PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis 15 d1kgsa1 99.6 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like 16 c1p2fA_ 99.6 42 PDB header:transcription Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure analysis of response regulator drrb, a2 thermotoga maritima ompr/phob homolog 17 d2ff4a1 99.6 12 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:PhoB-like 18 c3r0jA_ 99.5 17 PDB header:dna binding protein Chain: A: PDB Molecule:possible two component system response transcriptional PDBTitle: structure of phop from mycobacterium tuberculosis 19 c1kgsA_ 99.3 20 PDB header:dna binding protein Chain: A: PDB Molecule:dna binding response regulator d; PDBTitle: crystal structure at 1.50 a of an ompr/phob homolog from thermotoga2 maritima 20 c2ff4B_ 98.9 12 PDB header:transcription Chain: B: PDB Molecule:probable regulatory protein embr; PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide 21 d1biaa1 not modelled 95.9 22 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Biotin repressor-like 22 c3k69A_ not modelled 95.5 19 PDB header:transcription Chain: A: PDB Molecule:putative transcription regulator; PDBTitle: crystal structure of a putative transcriptional regulator (lp_0360)2 from lactobacillus plantarum at 1.95 a resolution 23 c2ewnA_ not modelled 94.4 20 PDB header:ligase, transcription Chain: A: PDB Molecule:bira bifunctional protein; PDBTitle: ecoli biotin repressor with co-repressor analog 24 d1j5ya1 not modelled 93.0 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Biotin repressor-like 25 d1ylfa1 not modelled 90.8 9 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Transcriptional regulator Rrf2 26 d1o57a1 not modelled 88.6 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:N-terminal domain of Bacillus PurR 27 c3lwfD_ not modelled 87.0 21 PDB header:transcription regulator Chain: D: PDB Molecule:putative transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator (np_470886.1)2 from listeria innocua at 2.06 a resolution 28 c2y75F_ not modelled 84.4 14 PDB header:transcription Chain: F: PDB Molecule:hth-type transcriptional regulator cymr; PDBTitle: the structure of cymr (yrzc) the global cysteine regulator2 of b. subtilis 29 c1j5yA_ not modelled 83.9 22 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, biotin repressor family; PDBTitle: crystal structure of transcriptional regulator (tm1602) from2 thermotoga maritima at 2.3 a resolution 30 d1t6sa1 not modelled 82.4 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:ScpB/YpuH-like 31 c3klnC_ not modelled 70.2 15 PDB header:transcription Chain: C: PDB Molecule:transcriptional regulator, luxr family; PDBTitle: vibrio cholerae vpst 32 c1rnlA_ not modelled 69.9 13 PDB header:signal transduction protein Chain: A: PDB Molecule:nitrate/nitrite response regulator protein narl; PDBTitle: the nitrate/nitrite response regulator protein narl from narl 33 c3c3wB_ not modelled 68.9 13 PDB header:transcription Chain: B: PDB Molecule:two component transcriptional regulatory protein devr; PDBTitle: crystal structure of the mycobacterium tuberculosis hypoxic response2 regulator dosr 34 d1xd7a_ not modelled 56.2 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Transcriptional regulator Rrf2 35 c1zn2A_ not modelled 52.2 25 PDB header:transcription regulator Chain: A: PDB Molecule:response regulatory protein; PDBTitle: low resolution structure of response regulator styr 36 c1t6sB_ not modelled 41.6 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of a conserved hypothetical protein from chlorobium2 tepidum 37 c2z99A_ not modelled 41.0 11 PDB header:cell cycle Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of scpb from mycobacterium tuberculosis 38 c2q0oA_ not modelled 39.7 17 PDB header:transcription Chain: A: PDB Molecule:probable transcriptional activator protein trar; PDBTitle: crystal structure of an anti-activation complex in bacterial quorum2 sensing 39 c2fu4B_ not modelled 37.7 15 PDB header:dna binding protein Chain: B: PDB Molecule:ferric uptake regulation protein; PDBTitle: crystal structure of the dna binding domain of e.coli fur (ferric2 uptake regulator) 40 c1o57A_ not modelled 33.1 13 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 41 c3sztB_ not modelled 33.0 17 PDB header:transcription Chain: B: PDB Molecule:quorum-sensing control repressor; PDBTitle: quorum sensing control repressor, qscr, bound to n-3-oxo-dodecanoyl-l-2 homoserine lactone 42 c1h0mD_ not modelled 32.7 29 PDB header:transcription/dna Chain: D: PDB Molecule:transcriptional activator protein trar; PDBTitle: three-dimensional structure of the quorum sensing protein2 trar bound to its autoinducer and to its target dna 43 c3qp5C_ not modelled 32.7 18 PDB header:transcription Chain: C: PDB Molecule:cvir transcriptional regulator; PDBTitle: crystal structure of cvir bound to antagonist chlorolactone (cl) 44 c2jpcA_ not modelled 31.5 12 PDB header:dna binding protein Chain: A: PDB Molecule:ssrb; PDBTitle: ssrb dna binding protein 45 d1l3la1 not modelled 27.1 29 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:GerE-like (LuxR/UhpA family of transcriptional regulators) 46 c3kfwX_ not modelled 26.2 15 PDB header:structural genomics, unknown function Chain: X: PDB Molecule:uncharacterized protein; PDBTitle: uncharacterized protein rv0674 from mycobacterium tuberculosis 47 c3kevA_ not modelled 25.4 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:galieria sulfuraria dcun1 domain-containing protein; PDBTitle: x-ray crystal structure of a dcun1 domain-containing protein from2 galdieria sulfuraria 48 c1zljE_ not modelled 25.3 10 PDB header:transcription Chain: E: PDB Molecule:dormancy survival regulator; PDBTitle: crystal structure of the mycobacterium tuberculosis hypoxic2 response regulator dosr c-terminal domain 49 c2w57A_ not modelled 24.3 18 PDB header:metal transport Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: crystal structure of the vibrio cholerae ferric uptake2 regulator (fur) reveals structural rearrangement of the3 dna-binding domains 50 d1yioa1 not modelled 22.9 24 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:GerE-like (LuxR/UhpA family of transcriptional regulators) 51 d1p4wa_ not modelled 21.6 6 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:GerE-like (LuxR/UhpA family of transcriptional regulators) 52 c3r0aB_ not modelled 20.8 21 PDB header:transcription regulator Chain: B: PDB Molecule:putative transcriptional regulator; PDBTitle: possible transcriptional regulator from methanosarcina mazei go1 (gi2 21227196) 53 d1fsea_ not modelled 20.3 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:GerE-like (LuxR/UhpA family of transcriptional regulators) 54 c1x3uA_ not modelled 19.6 24 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein fixj; PDBTitle: solution structure of the c-terminal transcriptional2 activator domain of fixj from sinorhizobium melilot 55 d1a04a1 not modelled 18.7 24 Fold:DNA/RNA-binding 3-helical bundle Superfamily:C-terminal effector domain of the bipartite response regulators Family:GerE-like (LuxR/UhpA family of transcriptional regulators) 56 c2is9A_ not modelled 17.0 9 PDB header:transcription Chain: A: PDB Molecule:defective in cullin neddylation protein 1; PDBTitle: structure of yeast dcn-1 57 c2o03A_ not modelled 15.1 22 PDB header:gene regulation Chain: A: PDB Molecule:probable zinc uptake regulation protein furb; PDBTitle: crystal structure of furb from m. tuberculosis- a zinc uptake2 regulator 58 c3mzyA_ not modelled 14.7 37 PDB header:rna binding protein Chain: A: PDB Molecule:rna polymerase sigma-h factor; PDBTitle: the crystal structure of the rna polymerase sigma-h factor from2 fusobacterium nucleatum to 2.5a 59 c2l5gB_ not modelled 13.5 21 PDB header:transcription regulator Chain: B: PDB Molecule:putative uncharacterized protein ncor2; PDBTitle: co-ordinates and 1h, 13c and 15n chemical shift assignments for the2 complex of gps2 53-90 and smrt 167-207 60 c3bq3A_ not modelled 13.5 9 PDB header:cell cycle, ligase Chain: A: PDB Molecule:defective in cullin neddylation protein 1; PDBTitle: crystal structure of s. cerevisiae dcn1 61 c3sqnB_ not modelled 13.1 13 PDB header:transcription regulator Chain: B: PDB Molecule:conserved domain protein; PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis 62 d1xsva_ not modelled 12.4 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors Family:YlxM/p13-like 63 c2rnjA_ not modelled 12.2 22 PDB header:transcription Chain: A: PDB Molecule:response regulator protein vrar; PDBTitle: nmr structure of the s. aureus vrar dna binding domain 64 d1jhfa1 not modelled 11.7 10 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:LexA repressor, N-terminal DNA-binding domain 65 d1mzba_ not modelled 11.5 11 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FUR-like 66 c2krfB_ not modelled 11.1 12 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulatory protein coma; PDBTitle: nmr solution structure of the dna binding domain of competence protein2 a 67 c3edpB_ not modelled 11.1 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:lin2111 protein; PDBTitle: the crystal structure of the protein lin2111 (functionally unknown)2 from listeria innocua clip11262 68 c2o8xA_ not modelled 11.0 17 PDB header:transcription Chain: A: PDB Molecule:probable rna polymerase sigma-c factor; PDBTitle: crystal structure of the "-35 element" promoter recognition domain of2 mycobacterium tuberculosis sigc 69 c3mwmA_ not modelled 10.8 17 PDB header:transcription Chain: A: PDB Molecule:putative metal uptake regulation protein; PDBTitle: graded expression of zinc-responsive genes through two regulatory2 zinc-binding sites in zur 70 d1hwua_ not modelled 10.5 19 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 71 d1ud0a_ not modelled 9.7 6 Fold:immunoglobulin/albumin-binding domain-like Superfamily:Heat shock protein 70kD (HSP70), C-terminal subdomain Family:Heat shock protein 70kD (HSP70), C-terminal subdomain 72 d1p6ra_ not modelled 9.3 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Penicillinase repressor 73 d1hw1a1 not modelled 9.3 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:GntR-like transcriptional regulators 74 c3cloC_ not modelled 9.0 18 PDB header:transcription regulator Chain: C: PDB Molecule:transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator containing a2 luxr dna binding domain (np_811094.1) from bacteroides3 thetaiotaomicron vpi-5482 at 2.04 a resolution 75 c3d0wD_ not modelled 8.5 5 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:yflh protein; PDBTitle: crystal structure of yflh protein from bacillus subtilis.2 northeast structural genomics consortium target sr326 76 d3bwga1 not modelled 8.5 16 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:GntR-like transcriptional regulators 77 c3ctzA_ not modelled 8.1 11 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro aminopeptidase 1; PDBTitle: structure of human cytosolic x-prolyl aminopeptidase 78 c2xigA_ not modelled 7.9 8 PDB header:transcription Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: the structure of the helicobacter pylori ferric uptake2 regulator fur reveals three functional metal binding sites 79 c3kz4A_ not modelled 7.9 17 PDB header:virus Chain: A: PDB Molecule:inner capsid protein vp2; PDBTitle: crystal structure of the rotavirus double layered particle 80 c2k4bA_ not modelled 7.9 20 PDB header:dna binding protein Chain: A: PDB Molecule:transcriptional regulator; PDBTitle: copr repressor structure 81 d1fcda2 not modelled 7.9 20 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 82 d1or7a1 not modelled 7.8 27 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors Family:Sigma4 domain 83 d1rrqa1 not modelled 7.8 20 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:Mismatch glycosylase 84 d2ieaa2 not modelled 7.6 17 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:TK-like PP module 85 c3bwgA_ not modelled 7.2 17 PDB header:transcription regulator Chain: A: PDB Molecule:uncharacterized hth-type transcriptional regulator yydk; PDBTitle: the crystal structure of possible transcriptional regulator yydk from2 bacillus subtilis subsp. subtilis str. 168 86 d1o98a1 not modelled 7.2 22 Fold:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Superfamily:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 87 c3by6C_ not modelled 7.1 19 PDB header:transcription regulator Chain: C: PDB Molecule:predicted transcriptional regulator; PDBTitle: crystal structure of a transcriptional regulator from oenococcus oeni 88 c2fe3B_ not modelled 7.1 13 PDB header:dna binding protein Chain: B: PDB Molecule:peroxide operon regulator; PDBTitle: the crystal structure of bacillus subtilis perr-zn reveals a novel2 zn(cys)4 structural redox switch 89 d2fb1a1 not modelled 6.9 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Nudix-associated domain 90 c1ud0B_ not modelled 6.9 6 PDB header:chaperone Chain: B: PDB Molecule:70 kda heat-shock-like protein; PDBTitle: crystal structure of the c-terminal 10-kda subdomain of hsc70 91 c3nw0B_ not modelled 6.8 18 PDB header:metal binding protein Chain: B: PDB Molecule:melanoma-associated antigen g1; PDBTitle: crystal structure of mageg1 and nse1 complex 92 c2wa0A_ not modelled 6.7 11 PDB header:immune system Chain: A: PDB Molecule:melanoma-associated antigen 4; PDBTitle: crystal structure of the human magea4 93 d2saka_ not modelled 6.5 13 Fold:beta-Grasp (ubiquitin-like) Superfamily:Staphylokinase/streptokinase Family:Staphylokinase/streptokinase 94 c2p32B_ not modelled 6.2 6 PDB header:chaperone Chain: B: PDB Molecule:heat shock 70 kda protein a; PDBTitle: crystal structure of the c-terminal 10 kda subdomain from c. elegans2 hsp70 95 d1ssna_ not modelled 6.0 13 Fold:beta-Grasp (ubiquitin-like) Superfamily:Staphylokinase/streptokinase Family:Staphylokinase/streptokinase 96 c3hugA_ not modelled 5.7 17 PDB header:transcription/membrane protein Chain: A: PDB Molecule:rna polymerase sigma factor; PDBTitle: crystal structure of mycobacterium tuberculosis anti-sigma factor rsla2 in complex with -35 promoter binding domain of sigl 97 c3neuA_ not modelled 5.7 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin1836 protein; PDBTitle: the crystal structure of a functionally-unknown protein lin1836 from2 listeria innocua clip11262 98 c3ketA_ not modelled 5.6 16 PDB header:transcription/dna Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: crystal structure of a rex-family transcriptional regulatory protein2 from streptococcus agalactiae bound to a palindromic operator 99 d2g9wa1 not modelled 5.6 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Penicillinase repressor

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0