Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	Q	F	A	S	P	V	L	H	S	L	L	D	T	D	A	Y	K	L	H	M	Q	Q	A	V	F	H	H	Y	Y	D	V	H	V	A	A	E	F	R	C	R	G	D	D	L	L	G	I	Y	A	D	A	I	R	E	Q	V	Q	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	Q	H	L	R	L	Q	D	D	E	Y	Q	W	L	S	A	L	P	F	F	K	A	D	Y	L	N	W	L	R	E	F	R	F	N	P	E	Q	V	T	V	S	N	D	N	G	K	L	D	I	R	L	S	G	P	W	R	E	V	I	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		W	E	V	P	L	L	A	V	I	S	E	M	V	H	R	Y	R	S	P	Q	A	D	V	A	Q	A	L	D	T	L	E	S	K	L	V	D	F	S	A	L	T	A	G	L	D	M	S	R	F	H	L	M	D	F	G	T	R	R	R	F
Secondary structure
SS confidence
Disorder																			?																										?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	R	E	V	Q	E	T	I	V	K	R	L	Q	Q	E	S	W	F	V	G	T	S	N	Y	D	L	A	R	R	L	S	L	T	P	M	G	T	Q	A	H	E	W	F	Q	A	H	Q	Q	I	S	P	D	L	A	N	S	Q	R	A	A
Secondary structure
SS confidence
Disorder																																																	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	A	A	W	L	E	E	Y	P	D	Q	L	G	I	A	L	T	D	C	I	T	M	D	A	F	L	R	D	F	G	V	E	F	A	S	R	Y	Q	G	L	R	H	D	S	G	D	P	V	E	W	G	E	K	A	I	A	H	Y	E	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	G	I	D	P	Q	S	K	T	L	V	F	S	D	N	L	D	L	R	K	A	V	E	L	Y	R	H	F	S	S	R	V	Q	L	S	F	G	I	G	T	R	L	T	C	D	I	P	Q	V	K	P	L	N	I	V	I	K	L	V	E
Secondary structure
SS confidence
Disorder																																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
Sequence		C	N	G	K	P	V	A	K	L	S	D	S	P	G	K	T	I	C	H	D	K	A	F	V	R	A	L	R	K	A	F	D	L	P	H	I	K	K	A	S
Secondary structure
SS confidence
Disorder															?	?	?	?																		?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3os4 chain A Region: 3 - 394 Aligned: 392 Modelled: 392 Confidence: 100.0% Identity: 72% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: the crystal structure of nicotinate phosphoribosyltransferase from2 yersinia pestis Phyre2 PDB 2im5 chain C Region: 8 - 393 Aligned: 377 Modelled: 386 Confidence: 100.0% Identity: 38% PDB header:transferase Chain: C: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of nicotinate phosphoribosyltransferase2 from porphyromonas gingivalis Phyre2 PDB 1vlp chain A Region: 5 - 392 Aligned: 380 Modelled: 387 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of a putative nicotinate phosphoribosyltransferase2 (yor209c, npt1) from saccharomyces cerevisiae at 1.75 a resolution Phyre2 PDB 1ybe chain A Region: 2 - 392 Aligned: 386 Modelled: 391 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate phosphoribosyltransferase Phyre2 PDB 1yir chain A Region: 4 - 385 Aligned: 382 Modelled: 382 Confidence: 100.0% Identity: 51% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase 2; PDBTitle: crystal structure of a nicotinate phosphoribosyltransferase Phyre2 PDB 2f7f chain A Region: 10 - 394 Aligned: 349 Modelled: 365 Confidence: 100.0% Identity: 24% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase, putative; PDBTitle: crystal structure of enterococcus faecalis putative nicotinate2 phosphoribosyltransferase, new york structural genomics consortium Phyre2 PDB 2e5c chain A Region: 9 - 385 Aligned: 349 Modelled: 360 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:nicotinamide phosphoribosyltransferase; PDBTitle: crystal structure of human nmprtase complexed with 5'-phosphoribosyl-2 1'-pyrophosphate Phyre2 PDB 2i14 chain B Region: 1 - 385 Aligned: 309 Modelled: 332 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from pyrococcus furiosus Phyre2 PDB 1yir chain A domain 1 Region: 141 - 385 Aligned: 245 Modelled: 245 Confidence: 100.0% Identity: 55% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: Monomeric nicotinate phosphoribosyltransferase C-terminal domain Phyre2 PDB 1ybe chain A domain 1 Region: 146 - 392 Aligned: 244 Modelled: 247 Confidence: 100.0% Identity: 37% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: Monomeric nicotinate phosphoribosyltransferase C-terminal domain Phyre2 PDB 1ytk chain A Region: 9 - 385 Aligned: 303 Modelled: 316 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase from thermoplasma PDBTitle: crystal structure of a nicotinate phosphoribosyltransferase from2 thermoplasma acidophilum with nicotinate mononucleotide Phyre2 PDB 1vlp chain A domain 2 Region: 140 - 392 Aligned: 244 Modelled: 253 Confidence: 100.0% Identity: 35% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: Monomeric nicotinate phosphoribosyltransferase C-terminal domain Phyre2 PDB 2f7f chain A domain 1 Region: 155 - 394 Aligned: 224 Modelled: 240 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 1ytd chain A domain 1 Region: 156 - 388 Aligned: 208 Modelled: 229 Confidence: 100.0% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 2i14 chain A domain 1 Region: 152 - 385 Aligned: 207 Modelled: 230 Confidence: 100.0% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 1yir chain A domain 2 Region: 2 - 140 Aligned: 139 Modelled: 139 Confidence: 100.0% Identity: 45% Fold: alpha/beta-Hammerhead Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like Family: Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like Phyre2 PDB 1vlp chain A domain 1 Region: 5 - 138 Aligned: 134 Modelled: 134 Confidence: 100.0% Identity: 31% Fold: alpha/beta-Hammerhead Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like Family: Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like Phyre2 PDB 1ybe chain A domain 2 Region: 6 - 141 Aligned: 134 Modelled: 136 Confidence: 100.0% Identity: 28% Fold: alpha/beta-Hammerhead Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like Family: Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like Phyre2 PDB 2f7f chain A domain 2 Region: 10 - 130 Aligned: 121 Modelled: 121 Confidence: 100.0% Identity: 21% Fold: alpha/beta-Hammerhead Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like Family: NadC N-terminal domain-like Phyre2 PDB 1x1o chain C Region: 9 - 360 Aligned: 260 Modelled: 293 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 Phyre2 1 c3os4A_ 2 c2im5C_ 3 c1vlpA_ 4 c1ybeA_ 5 c1yirA_ 6 c2f7fA_ 7 c2e5cA_ 8 c2i14B_ 9 d1yira1 10 d1ybea1 11 c1ytkA_ 12 d1vlpa2 13 d2f7fa1 14 d1ytda1 15 d2i14a1 16 d1yira2 17 d1vlpa1 18 d1ybea2 19 d2f7fa2 20 c1x1oC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3os4A_ 100.0 72 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: the crystal structure of nicotinate phosphoribosyltransferase from2 yersinia pestis 2 c2im5C_ 100.0 38 PDB header:transferase Chain: C: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of nicotinate phosphoribosyltransferase2 from porphyromonas gingivalis 3 c1vlpA_ 100.0 33 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of a putative nicotinate phosphoribosyltransferase2 (yor209c, npt1) from saccharomyces cerevisiae at 1.75 a resolution 4 c1ybeA_ 100.0 33 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate phosphoribosyltransferase 5 c1yirA_ 100.0 51 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase 2; PDBTitle: crystal structure of a nicotinate phosphoribosyltransferase 6 c2f7fA_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase, putative; PDBTitle: crystal structure of enterococcus faecalis putative nicotinate2 phosphoribosyltransferase, new york structural genomics consortium 7 c2e5cA_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:nicotinamide phosphoribosyltransferase; PDBTitle: crystal structure of human nmprtase complexed with 5'-phosphoribosyl-2 1'-pyrophosphate 8 c2i14B_ 100.0 20 PDB header:transferase Chain: B: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from pyrococcus furiosus 9 d1yira1 100.0 55 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase C-terminal domain 10 d1ybea1 100.0 37 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase C-terminal domain 11 c1ytkA_ 100.0 22 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase from thermoplasma PDBTitle: crystal structure of a nicotinate phosphoribosyltransferase from2 thermoplasma acidophilum with nicotinate mononucleotide 12 d1vlpa2 100.0 35 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase C-terminal domain 13 d2f7fa1 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 14 d1ytda1 100.0 22 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 15 d2i14a1 100.0 22 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 16 d1yira2 100.0 45 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like 17 d1vlpa1 100.0 31 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like 18 d1ybea2 100.0 28 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like 19 d2f7fa2 100.0 21 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 20 c1x1oC_ 99.9 17 PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 21 c2b7pA_ not modelled 99.9 14 PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori 22 c3l0gD_ not modelled 99.9 14 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 23 c1qpoA_ not modelled 99.9 15 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 24 c3pajA_ not modelled 99.9 17 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 25 c2jbmA_ not modelled 99.9 16 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human 26 c1o4uA_ not modelled 99.8 15 PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution 27 c1qapA_ not modelled 99.8 17 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 28 c3tqvA_ not modelled 99.8 14 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis. 29 d2i14a2 not modelled 99.8 13 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 30 c3gnnA_ not modelled 99.7 18 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei 31 d1ytda2 not modelled 99.7 19 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 32 c3c2vA_ not modelled 99.6 17 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of the quinolinate phosphoribosyl2 transferase (bna6) from saccharomyces cerevisiae complexed3 with prpp and the inhibitor phthalate 33 d1qapa1 not modelled 99.6 18 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 34 d1qpoa1 not modelled 99.5 18 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 35 d1o4ua1 not modelled 97.7 9 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 36 d1gwja_ not modelled 73.6 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 37 d1rpxa_ not modelled 72.7 8 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 38 c3cu2A_ not modelled 72.1 10 PDB header:isomerase Chain: A: PDB Molecule:ribulose-5-phosphate 3-epimerase; PDBTitle: crystal structure of ribulose-5-phosphate 3-epimerase (yp_718263.1)2 from haemophilus somnus 129pt at 1.91 a resolution 39 d2flia1 not modelled 62.7 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 40 c3absD_ not modelled 58.3 20 PDB header:lyase Chain: D: PDB Molecule:ethanolamine ammonia-lyase light chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with adeninylpentylcobalamin and ethanolamine 41 d2j9ga1 not modelled 57.6 20 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:BC C-terminal domain-like 42 c3inpA_ not modelled 57.3 10 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 43 d1ulza1 not modelled 57.2 18 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:BC C-terminal domain-like 44 d1vyra_ not modelled 54.3 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 45 d1icpa_ not modelled 53.9 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 46 c3qjaA_ not modelled 51.9 12 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 47 c1ni4D_ not modelled 51.9 17 PDB header:oxidoreductase Chain: D: PDB Molecule:pyruvate dehydrogenase e1 component: beta PDBTitle: human pyruvate dehydrogenase 48 d2ozlb2 not modelled 51.5 18 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain 49 d1xi3a_ not modelled 50.5 11 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 50 d1a53a_ not modelled 48.9 24 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 51 d1tqxa_ not modelled 47.0 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 52 d1vhca_ not modelled 45.8 6 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 53 d1tqja_ not modelled 44.9 9 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 54 c3labA_ not modelled 44.3 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 55 d1mxsa_ not modelled 44.3 3 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 56 d1wbha1 not modelled 44.0 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 57 c2h90A_ not modelled 43.9 17 PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin 58 d1vjia_ not modelled 42.1 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 59 c2v82A_ not modelled 41.1 11 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 60 d1yxya1 not modelled 40.5 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 61 c3ct7E_ not modelled 40.2 12 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 62 c3dl2A_ not modelled 40.1 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ubiquitin-conjugating enzyme e2 variant 3; PDBTitle: hexagonal structure of the ldh domain of human ubiquitin-2 conjugating enzyme e2-like isoform a 63 d1r0ma1 not modelled 39.5 18 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 64 d1luca_ not modelled 39.3 22 Fold:TIM beta/alpha-barrel Superfamily:Bacterial luciferase-like Family:Bacterial luciferase (alkanal monooxygenase) 65 c2c3zA_ not modelled 38.3 26 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 66 d1h1ya_ not modelled 37.3 8 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 67 d2tpsa_ not modelled 36.3 8 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 68 c1wueA_ not modelled 36.3 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:mandelate racemase/muconate lactonizing enzyme family PDBTitle: crystal structure of protein gi:29375081, unknown member of enolase2 superfamily from enterococcus faecalis v583 69 d1lvaa3 not modelled 36.2 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:C-terminal fragment of elongation factor SelB 70 d7reqa2 not modelled 35.5 15 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 71 c3anyB_ not modelled 35.3 16 PDB header:lyase Chain: B: PDB Molecule:ethanolamine ammonia-lyase light chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with cn-cbl and (r)-2-amino-1-propanol 72 c2h9aA_ not modelled 34.5 14 PDB header:oxidoreductase Chain: A: PDB Molecule:carbon monoxide dehydrogenase corrinoid/iron- PDBTitle: corrinoid iron-sulfur protein 73 c3o63B_ not modelled 32.6 7 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 74 d1wuea1 not modelled 32.5 18 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 75 c3atyA_ not modelled 31.6 19 PDB header:oxidoreductase Chain: A: PDB Molecule:prostaglandin f2a synthase; PDBTitle: crystal structure of tcoye 76 c1m6vE_ not modelled 30.8 18 PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase 77 c3qc3B_ not modelled 27.6 9 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 78 d1wufa1 not modelled 27.5 15 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 79 c2bdqA_ not modelled 27.3 13 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 80 d1sjda1 not modelled 26.2 14 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 81 c3gkxB_ not modelled 25.4 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative arsc family related protein; PDBTitle: crystal structure of putative arsc family related protein from2 bacteroides fragilis 82 d1xcfa_ not modelled 24.9 8 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 83 c1hvxA_ not modelled 24.6 5 PDB header:hydrolase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: bacillus stearothermophilus alpha-amylase 84 c2j7pA_ not modelled 22.2 12 PDB header:signal recognition Chain: A: PDB Molecule:signal recognition particle protein; PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy 85 c1hyhA_ not modelled 22.1 17 PDB header:oxidoreductase (choh(d)-nad+(a)) Chain: A: PDB Molecule:l-2-hydroxyisocaproate dehydrogenase; PDBTitle: crystal structure of l-2-hydroxyisocaproate dehydrogenase from2 lactobacillus confusus at 2.2 angstroms resolution-an example of3 strong asymmetry between subunits 86 c1ojuA_ not modelled 21.7 21 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: 2.8 a resolution structure of malate dehydrogenase from2 archaeoglobus fulgidus in complex with etheno-nad. 87 c3kwpA_ not modelled 21.6 11 PDB header:transferase Chain: A: PDB Molecule:predicted methyltransferase; PDBTitle: crystal structure of putative methyltransferase from lactobacillus2 brevis 88 c1yadD_ not modelled 21.5 4 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 89 c3m4wH_ not modelled 21.0 44 PDB header:signaling protein/signaling protein Chain: H: PDB Molecule:sigma-e factor negative regulatory protein; PDBTitle: structural basis for the negative regulation of bacterial stress2 response by rseb 90 c1zfjA_ not modelled 20.4 19 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 91 c3gkaB_ not modelled 19.5 13 PDB header:oxidoreductase Chain: B: PDB Molecule:n-ethylmaleimide reductase; PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei 92 c2ekcA_ not modelled 19.4 13 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 93 d1bqga1 not modelled 18.9 18 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 94 d1fuia1 not modelled 18.5 23 Fold:Reductase/isomerase/elongation factor common domain Superfamily:FucI/AraA C-terminal domain-like Family:L-fucose isomerase, C-terminal domain 95 c1sjaA_ not modelled 18.3 13 PDB header:lyase, isomerase Chain: A: PDB Molecule:n-acylamino acid racemase; PDBTitle: x-ray structure of o-succinylbenzoate synthase complexed2 with n-acetylmethionine 96 c3q58A_ not modelled 18.1 12 PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica 97 d2dfaa1 not modelled 18.0 21 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:LamB/YcsF-like 98 d2f9ya1 not modelled 17.9 20 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 99 d1twda_ not modelled 17.7 16 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0