Email l.a.kelley@imperial.ac.uk Description P27896 Date Wed Jan 25 15:20:46 GMT 2012 Unique Job ID 414ef1f881fad2a2

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2c2aA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:sensor histidine kinase; PDBTitle: structure of the entire cytoplasmic portion of a sensor2 histidine kinase protein 2 c3d2rB_ 100.0 17 PDB header:transferase Chain: B: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 4; PDBTitle: crystal structure of pyruvate dehydrogenase kinase isoform 4 in2 complex with adp 3 c1gjvA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:[3-methyl-2-oxobutanoate dehydrogenase PDBTitle: branched-chain alpha-ketoacid dehydrogenase kinase (bck)2 complxed with atp-gamma-s 4 c3d36B_ 100.0 18 PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:sporulation kinase b; PDBTitle: how to switch off a histidine kinase: crystal structure of2 geobacillus stearothermophilus kinb with the inhibitor sda 5 c2q8fA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; PDBTitle: structure of pyruvate dehydrogenase kinase isoform 1 6 c2bu8A_ 100.0 14 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase kinase isoenzyme 2; PDBTitle: crystal structures of human pyruvate dehydrogenase kinase 22 containing physiological and synthetic ligands 7 c1y8oA_ 100.0 13 PDB header:transferase Chain: A: PDB Molecule:[pyruvate dehydrogenase [lipoamide]] kinase isozyme 3; PDBTitle: crystal structure of the pdk3-l2 complex 8 c1b3qA_ 99.9 18 PDB header:transferase Chain: A: PDB Molecule:protein (chemotaxis protein chea); PDBTitle: crystal structure of chea-289, a signal transducing histidine kinase 9 c3a0rA_ 99.9 12 PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360) 10 c2ch4A_ 99.9 23 PDB header:transferase/chemotaxis Chain: A: PDB Molecule:chemotaxis protein chea; PDBTitle: complex between bacterial chemotaxis histidine kinase chea2 domains p4 and p5 and receptor-adaptor protein chew 11 d2c2aa2 99.9 17 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase 12 d1gkza2 99.9 23 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain 13 d1jm6a2 99.9 20 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain 14 d1ysra1 99.9 20 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase 15 d1id0a_ 99.9 17 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase 16 d1i58a_ 99.9 23 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase 17 d1bxda_ 99.9 18 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase 18 c3gieA_ 99.9 21 PDB header:transferase Chain: A: PDB Molecule:sensor histidine kinase desk; PDBTitle: crystal structure of deskc_h188e in complex with amp-pcp 19 c3a0tA_ 99.9 15 PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: catalytic domain of histidine kinase thka (tm1359) in2 complex with adp and mg ion (trigonal) 20 c3jz3B_ 99.9 23 PDB header:transferase Chain: B: PDB Molecule:sensor protein qsec; PDBTitle: structure of the cytoplasmic segment of histidine kinase qsec 21 c3ehgA_ not modelled 99.8 22 PDB header:transferase Chain: A: PDB Molecule:sensor kinase (yocf protein); PDBTitle: crystal structure of the atp-binding domain of desk in complex with2 atp 22 c3zxqA_ not modelled 99.8 30 PDB header:transferase Chain: A: PDB Molecule:hypoxia sensor histidine kinase response regulator dost; PDBTitle: crystal structure of the atp-binding domain of mycobacterium2 tuberculosis dost 23 c3zxoB_ not modelled 99.8 27 PDB header:transferase Chain: B: PDB Molecule:redox sensor histidine kinase response regulator devs; PDBTitle: crystal structure of the mutant atp-binding domain of2 mycobacterium tuberculosis doss 24 d1r62a_ not modelled 99.7 15 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase 25 d2hkja3 not modelled 99.6 15 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 26 d1th8a_ not modelled 99.5 22 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase 27 c2zbkB_ not modelled 99.5 16 PDB header:isomerase Chain: B: PDB Molecule:type 2 dna topoisomerase 6 subunit b; PDBTitle: crystal structure of an intact type ii dna topoisomerase:2 insights into dna transfer mechanisms 28 c1mx0D_ not modelled 99.4 16 PDB header:isomerase Chain: D: PDB Molecule:type ii dna topoisomerase vi subunit b; PDBTitle: structure of topoisomerase subunit 29 c2q2eB_ not modelled 99.4 23 PDB header:isomerase Chain: B: PDB Molecule:type 2 dna topoisomerase 6 subunit b; PDBTitle: crystal structure of the topoisomerase vi holoenzyme from2 methanosarcina mazei 30 d1ixma_ not modelled 99.3 13 Fold:Sporulation response regulatory protein Spo0B Superfamily:Sporulation response regulatory protein Spo0B Family:Sporulation response regulatory protein Spo0B 31 d1h7sa2 not modelled 99.3 21 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 32 d1bkna2 not modelled 99.0 22 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 33 d1y8oa2 not modelled 98.9 13 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:alpha-ketoacid dehydrogenase kinase, C-terminal domain 34 d1b63a2 not modelled 98.9 22 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 35 c3na3A_ not modelled 98.5 24 PDB header:protein binding Chain: A: PDB Molecule:dna mismatch repair protein mlh1; PDBTitle: mutl protein homolog 1 isoform 1 from homo sapiens 36 c3h4lB_ not modelled 98.5 27 PDB header:dna binding protein, protein binding Chain: B: PDB Molecule:dna mismatch repair protein pms1; PDBTitle: crystal structure of n terminal domain of a dna repair protein 37 c1ea6A_ not modelled 98.4 23 PDB header:dna repair Chain: A: PDB Molecule:pms1 protein homolog 2; PDBTitle: n-terminal 40kda fragment of nhpms2 complexed with adp 38 c1bknA_ not modelled 98.3 27 PDB header:dna repair Chain: A: PDB Molecule:mutl; PDBTitle: crystal structure of an n-terminal 40kd fragment of e. coli2 dna mismatch repair protein mutl 39 d1kija2 not modelled 98.2 32 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 40 c3ke6A_ not modelled 98.2 31 PDB header:unknown function Chain: A: PDB Molecule:protein rv1364c/mt1410; PDBTitle: the crystal structure of the rsbu and rsbw domains of rv1364c from2 mycobacterium tuberculosis 41 c1kijB_ not modelled 98.1 38 PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit b; PDBTitle: crystal structure of the 43k atpase domain of thermus thermophilus2 gyrase b in complex with novobiocin 42 d1s16a2 not modelled 98.1 18 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 43 d1pvga2 not modelled 98.1 24 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 44 c1s16B_ not modelled 98.0 21 PDB header:isomerase Chain: B: PDB Molecule:topoisomerase iv subunit b; PDBTitle: crystal structure of e. coli topoisomerase iv pare 43kda subunit2 complexed with adpnp 45 c1y4sA_ not modelled 98.0 27 PDB header:chaperone Chain: A: PDB Molecule:chaperone protein htpg; PDBTitle: conformation rearrangement of heat shock protein 90 upon2 adp binding 46 c3g7bB_ not modelled 98.0 26 PDB header:isomerase Chain: B: PDB Molecule:dna gyrase subunit b; PDBTitle: staphylococcus aureus gyrase b co-complex with inhibitor 47 d1ei1a2 not modelled 97.9 36 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 48 c1ei1B_ not modelled 97.9 34 PDB header:isomerase Chain: B: PDB Molecule:dna gyrase b; PDBTitle: dimerization of e. coli dna gyrase b provides a structural mechanism2 for activating the atpase catalytic center 49 c2o1uA_ not modelled 97.9 19 PDB header:chaperone Chain: A: PDB Molecule:endoplasmin; PDBTitle: structure of full length grp94 with amp-pnp bound 50 d1s14a_ not modelled 97.9 20 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 51 c3lnuA_ not modelled 97.8 27 PDB header:isomerase Chain: A: PDB Molecule:topoisomerase iv subunit b; PDBTitle: crystal structure of pare subunit 52 c3pehB_ not modelled 97.8 23 PDB header:chaperone Chain: B: PDB Molecule:endoplasmin homolog; PDBTitle: crystal structure of the n-terminal domain of an hsp90 from plasmodium2 falciparum, pfl1070c in the presence of a thienopyrimidine derivative 53 c2cg9A_ not modelled 97.8 27 PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: crystal structure of an hsp90-sba1 closed chaperone complex 54 d1uyma_ not modelled 97.8 25 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain 55 c3eziB_ 97.8 28 PDB header:transferase Chain: B: PDB Molecule:nitrate/nitrite sensor protein narx; PDBTitle: crystal structure of the e. coli histidine kinase narx2 sensor domain without ligand 56 c1zxnB_ not modelled 97.7 30 PDB header:isomerase Chain: B: PDB Molecule:dna topoisomerase ii, alpha isozyme; PDBTitle: human dna topoisomerase iia atpase/adp 57 c2iopD_ not modelled 97.7 25 PDB header:chaperone Chain: D: PDB Molecule:chaperone protein htpg; PDBTitle: crystal structure of full-length htpg, the escherichia coli2 hsp90, bound to adp 58 c1zwhA_ not modelled 97.7 26 PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: yeast hsp82 in complex with the novel hsp90 inhibitor radester amine 59 d2iwxa1 not modelled 97.7 26 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain 60 c1qzrA_ not modelled 97.6 28 PDB header:isomerase Chain: A: PDB Molecule:dna topoisomerase ii; PDBTitle: crystal structure of the atpase region of saccharomyces cerevisiae2 topoisomerase ii bound to icrf-187 (dexrazoxane) 61 d2c2aa1 not modelled 97.6 14 Fold:ROP-like Superfamily:Homodimeric domain of signal transducing histidine kinase Family:Homodimeric domain of signal transducing histidine kinase 62 c2fwyA_ not modelled 97.6 18 PDB header:chaperone Chain: A: PDB Molecule:heat shock protein hsp 90-alpha; PDBTitle: structure of human hsp90-alpha bound to the potent water2 soluble inhibitor pu-h64 63 d1uyla_ not modelled 97.5 18 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain 64 c2akpA_ not modelled 97.4 19 PDB header:chaperone Chain: A: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: hsp90 delta24-n210 mutant 65 c3iedA_ not modelled 97.2 25 PDB header:chaperone Chain: A: PDB Molecule:heat shock protein; PDBTitle: crystal structure of n-terminal domain of plasmodium falciparum hsp902 (pf14_0417) in complex with amppn 66 d1joya_ not modelled 97.1 10 Fold:ROP-like Superfamily:Homodimeric domain of signal transducing histidine kinase Family:Homodimeric domain of signal transducing histidine kinase 67 c2iorA_ not modelled 97.0 30 PDB header:chaperone Chain: A: PDB Molecule:chaperone protein htpg; PDBTitle: crystal structure of the n-terminal domain of htpg, the2 escherichia coli hsp90, bound to adp 68 d1qy5a_ not modelled 97.0 25 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain 69 c2o1wB_ not modelled 97.0 25 PDB header:chaperone Chain: B: PDB Molecule:endoplasmin; PDBTitle: structure of n-terminal plus middle domains (n+m) of grp94 70 d2gqpa1 not modelled 96.9 19 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Heat shock protein 90, HSP90, N-terminal domain 71 c3zrwB_ not modelled 95.7 7 PDB header:signaling protein Chain: B: PDB Molecule:af1503 protein, osmolarity sensor protein envz; PDBTitle: the structure of the dimeric hamp-dhp fusion a291v mutant 72 c3cwvB_ not modelled 95.2 11 PDB header:isomerase Chain: B: PDB Molecule:dna gyrase, b subunit, truncated; PDBTitle: crystal structure of b-subunit of the dna gyrase from myxococcus2 xanthus 73 c3lmmA_ not modelled 77.4 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the dip2311 protein from2 corynebacterium diphtheriae, northeast structural genomics3 consortium target cdr35 74 d2asxa1 55.9 21 Fold:HAMP domain-like Superfamily:HAMP domain-like Family:HAMP domain 75 c3k7pA_ not modelled 43.3 17 PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: structure of mutant of ribose 5-phosphate isomerase type b from2 trypanosoma cruzi. 76 c3m1pA_ not modelled 43.1 17 PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: structure of ribose 5-phosphate isomerase type b from trypanosoma2 cruzi, soaked with allose-6-phosphate 77 d1j0ga_ not modelled 41.1 22 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:BM-002-like 78 d1xb2b1 not modelled 28.3 26 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain 79 d1efub3 not modelled 28.2 11 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain 80 d2cp9a1 not modelled 27.9 26 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain 81 d1aipc1 not modelled 22.6 16 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:TS-N domain 82 c2kseA_ not modelled 19.2 11 PDB header:transferase Chain: A: PDB Molecule:sensor protein qsec; PDBTitle: backbone structure of the membrane domain of e. coli2 histidine kinase receptor qsec, center for structures of3 membrane proteins (csmp) target 4311c 83 d1c8ba_ not modelled 18.9 50 Fold:Phosphorylase/hydrolase-like Superfamily:HybD-like Family:Germination protease 84 d1wxsa1 not modelled 18.2 29 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:BM-002-like 85 d1l7ya_ not modelled 17.2 17 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:BM-002-like 86 c2crqA_ not modelled 17.0 22 PDB header:translation Chain: A: PDB Molecule:mitochondrial translational initiation factor 3; PDBTitle: solution structure of c-terminal domain of riken cdna2 2810012l14 87 d1g0oa_ not modelled 16.2 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 88 c2jnvA_ not modelled 15.9 19 PDB header:metal transport Chain: A: PDB Molecule:nifu-like protein 1, chloroplast; PDBTitle: solution structure of c-terminal domain of nifu-like2 protein from oryza sativa 89 d1nn4a_ not modelled 15.4 22 Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB 90 c3s8mA_ not modelled 15.2 22 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acp reductase; PDBTitle: the crystal structure of fabv 91 d1fx7a3 not modelled 13.9 28 Fold:SH3-like barrel Superfamily:C-terminal domain of transcriptional repressors Family:FeoA-like 92 d2d7na1 not modelled 13.7 18 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Filamin repeat (rod domain) 93 d1xmta_ not modelled 13.5 11 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT 94 c3qivA_ not modelled 13.2 18 PDB header:oxidoreductase Chain: A: PDB Molecule:short-chain dehydrogenase or 3-oxoacyl-[acyl-carrier- PDBTitle: crystal structure of a putative short-chain dehydrogenase or 3-2 oxoacyl-[acyl-carrier-protein] reductase from mycobacterium3 paratuberculosis atcc baa-968 / k-10 95 d1s98a_ not modelled 13.0 21 Fold:HesB-like domain Superfamily:HesB-like domain Family:HesB-like domain 96 d1veha_ not modelled 12.8 15 Fold:Alpha-lytic protease prodomain-like Superfamily:Fe-S cluster assembly (FSCA) domain-like Family:NifU C-terminal domain-like 97 d1odka_ not modelled 12.8 12 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 98 c3lnrA_ not modelled 12.7 11 PDB header:signaling protein Chain: A: PDB Molecule:aerotaxis transducer aer2; PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2 99 c3k6oA_ not modelled 12.7 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein duf1344; PDBTitle: crystal structure of protein of unknown function duf13442 (yp_001299214.1) from bacteroides vulgatus atcc 8482 at 2.00 a3 resolution