PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: d1pvga2

Fold library id	Fold	Superfamily	Family
d1pvga2	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA gyrase/MutL, N-terminal domain

Links to external resources
Added to library: Tue Mar 16 12:32:16 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S A S D K Y Q K I S Q L E H I L K R P D T Y I G S V E T Q E Q L Q W I Y D E E T D C X I E K N V T I V P G L F K I F D E I L V N A A D N K V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence R D P S X K R I D V N I H A E E H T I E V K N D G K G I P I E I H N K E N I Y I P E X I F G H L L T S S N Y D D D E K K V T G G R N G Y G A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T T T T S S
S B
T T T
S B S S S
S
T T S
S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K L C N I F S T E F I L E T A D L N V G Q K Y V Q K W E N N X S I C H P P K I T S Y K K G P S Y T K V T F K P D L T R F G X K E L D N D I L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T T T T T T
S S
G G G G T
S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . .

Sequence G V X R R R V Y D I N G S V R D I N V Y L N G K S L K I R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	A	S	D	K	Y	Q	K	I	S	Q	L	E	H	I	L	K	R	P	D	T	Y	I	G	S	V	E	T	Q	E	Q	L	Q	W	I	Y	D	E	E	T	D	C	X	I	E	K	N	V	T	I	V	P	G	L	F	K	I	F	D	E	I	L	V	N	A	A	D	N	K	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S																				S	S											T	T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	R	D	P	S	X	K	R	I	D	V	N	I	H	A	E	E	H	T	I	E	V	K	N	D	G	K	G	I	P	I	E	I	H	N	K	E	N	I	Y	I	P	E	X	I	F	G	H	L	L	T	S	S	N	Y	D	D	D	E	K	K	V	T	G	G	R	N	G	Y	G	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T										T	T	T	T								S	S					S	B		T	T	T		S	B								S	S	S			S				T	T	S					S			S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	L	C	N	I	F	S	T	E	F	I	L	E	T	A	D	L	N	V	G	Q	K	Y	V	Q	K	W	E	N	N	X	S	I	C	H	P	P	K	I	T	S	Y	K	K	G	P	S	Y	T	K	V	T	F	K	P	D	L	T	R	F	G	X	K	E	L	D	N	D	I	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T											T	T	T	T									T	T	T	T												S	S												G	G	G	G	T		S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Sequence	G	V	X	R	R	R	V	Y	D	I	N	G	S	V	R	D	I	N	V	Y	L	N	G	K	S	L	K	I	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S	T	T						T	T