PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: d1s16a2

Fold library id	Fold	Superfamily	Family
d1s16a2	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA gyrase/MutL, N-terminal domain

Links to external resources
Added to library: Tue Mar 16 13:09:45 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence T Y N A D A I E V L T G L E P V R R R P G M Y T D T T R P N H L G Q E V I D N S V D E A L A G H A K R V D V I L H A D Q S L E V I D D G R G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S G G G
T T
G G G T S
T T S T T T
S
T T S
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence M P V D I H P E E G V P A V E L I L C R L H A G G K F S N K N Y Q F S G G L H G V G I S V V N A L S K R V E V N V R R D G Q V Y N I A F E N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S B
T T T
S B
T T
S S
S S S S S
S S
S
S S
T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G E K V Q D L Q V V G T C G K R N T G T S V H F W P D E T F F D S P R F S V S R L T H V L K A K A V L C P G V E I T F K D E I N N T E Q R W

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
G G G S S
S
S T T
T T T T

. . .

Sequence C Y Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	T	Y	N	A	D	A	I	E	V	L	T	G	L	E	P	V	R	R	R	P	G	M	Y	T	D	T	T	R	P	N	H	L	G	Q	E	V	I	D	N	S	V	D	E	A	L	A	G	H	A	K	R	V	D	V	I	L	H	A	D	Q	S	L	E	V	I	D	D	G	R	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	G	G	G						T	T							G	G	G	T	S		T	T	S	T																	T	T			S								T	T	S								S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	M	P	V	D	I	H	P	E	E	G	V	P	A	V	E	L	I	L	C	R	L	H	A	G	G	K	F	S	N	K	N	Y	Q	F	S	G	G	L	H	G	V	G	I	S	V	V	N	A	L	S	K	R	V	E	V	N	V	R	R	D	G	Q	V	Y	N	I	A	F	E	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S	B		T	T	T		S	B									T	T		S	S		S	S	S	S	S		S	S		S			S	S									T											T	T									T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	E	K	V	Q	D	L	Q	V	V	G	T	C	G	K	R	N	T	G	T	S	V	H	F	W	P	D	E	T	F	F	D	S	P	R	F	S	V	S	R	L	T	H	V	L	K	A	K	A	V	L	C	P	G	V	E	I	T	F	K	D	E	I	N	N	T	E	Q	R	W
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T														T	T												G	G	G	S	S			S																	S	T	T								T	T	T	T
	.	.	.
Sequence	C	Y	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)