PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: d1b63a2

Fold library id	Fold	Superfamily	Family
d1b63a2	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA gyrase/MutL, N-terminal domain

Links to external resources
Added to library: Tue Mar 16 13:36:59 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S H M P I Q V L P P Q L A N Q I A A G E V V E R P A S V V K E L V E N S L D A G A T R I D I D I E R G G A K L I R I R D N G C G I K K D E L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S T T
S G G G T S
S
G G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence A L A L A R H A T S K I A S L D D L E A I I S L G F R G E A L A S I S S V S R L T L T S R T A E Q Q E A W Q A Y A E G R D M N V T V K P A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T
S S
S T
S S
S S
T T S
T T
S S T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence H P V G T T L E V L D L F Y N T P A R R K F L R T E K T E F N H I D E I I R R I A L A R F D V T I N L S H N G K I V R Q Y R A V P E G G Q K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T T T
T
T T
T T
T T
T

. . . . . . . .

Sequence E R R L G A I C

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	H	M	P	I	Q	V	L	P	P	Q	L	A	N	Q	I	A	A	G	E	V	V	E	R	P	A	S	V	V	K	E	L	V	E	N	S	L	D	A	G	A	T	R	I	D	I	D	I	E	R	G	G	A	K	L	I	R	I	R	D	N	G	C	G	I	K	K	D	E	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S																				S	S															T	T		S								G	G	G	T	S								S					G	G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	A	L	A	L	A	R	H	A	T	S	K	I	A	S	L	D	D	L	E	A	I	I	S	L	G	F	R	G	E	A	L	A	S	I	S	S	V	S	R	L	T	L	T	S	R	T	A	E	Q	Q	E	A	W	Q	A	Y	A	E	G	R	D	M	N	V	T	V	K	P	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	T	T			S	S			S						T			S	S			S	S								T	T	S									T	T		S	S								T	T	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	H	P	V	G	T	T	L	E	V	L	D	L	F	Y	N	T	P	A	R	R	K	F	L	R	T	E	K	T	E	F	N	H	I	D	E	I	I	R	R	I	A	L	A	R	F	D	V	T	I	N	L	S	H	N	G	K	I	V	R	Q	Y	R	A	V	P	E	G	G	Q	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S								S	T	T	T	T							T																							T	T								T	T											T	T			T
	.	.	.	.	.	.	.	.
Sequence	E	R	R	L	G	A	I	C
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)