Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	K	P	I	V	F	S	G	A	Q	P	S	G	E	L	T	I	G	N	Y	M	G	A	L	R	Q	W	V	N	M	Q	D	D	Y	H	C	I	Y	C	I	V	D	Q	H	A	I	T	V	R	Q	D	A	Q	K	L	R	K	A	T
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	D	T	L	A	L	Y	L	A	C	G	I	D	P	E	K	S	T	I	F	V	Q	S	H	V	P	E	H	A	Q	L	G	W	A	L	N	C	Y	T	Y	F	G	E	L	S	R	M	T	Q	F	K	D	K	S	A	R	Y	A	E	N
Secondary structure
SS confidence
Disorder																																							?	?	?																?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	N	A	G	L	F	D	Y	P	V	L	M	A	A	D	I	L	L	Y	Q	T	N	L	V	P	V	G	E	D	Q	K	Q	H	L	E	L	S	R	D	I	A	Q	R	F	N	A	L	Y	G	E	I	F	K	V	P	E	P	F	I	P
Secondary structure
SS confidence
Disorder																																																										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	S	G	A	R	V	M	S	L	L	E	P	T	K	K	M	S	K	S	D	D	N	R	N	N	V	I	G	L	L	E	D	P	K	S	V	V	K	K	I	K	R	A	V	T	D	S	D	E	P	P	V	V	R	Y	D	V	Q	N	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																							?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	G	V	S	N	L	L	D	I	L	S	A	V	T	G	Q	S	I	P	E	L	E	K	Q	F	E	G	K	M	Y	G	H	L	K	G	E	V	A	D	A	V	S	G	M	L	T	E	L	Q	E	R	Y	H	R	F	R	N	D	E	A
Secondary structure
SS confidence
Disorder																																																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.
Sequence		F	L	Q	Q	V	M	K	D	G	A	E	K	A	S	A	H	A	S	R	T	L	K	A	V	Y	E	A	I	G	F	V	A	K	P
Secondary structure
SS confidence
Disorder																													?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3n9i chain A Region: 3 - 334 Aligned: 332 Modelled: 332 Confidence: 100.0% Identity: 86% PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from yersinia pestis2 co92 Phyre2 PDB 3sz3 chain A Region: 1 - 334 Aligned: 334 Modelled: 334 Confidence: 100.0% Identity: 68% PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from vibrio cholerae2 with an endogenous tryptophan Phyre2 PDB 1i6l chain A Region: 4 - 332 Aligned: 325 Modelled: 329 Confidence: 100.0% Identity: 56% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 3prh chain B Region: 3 - 332 Aligned: 309 Modelled: 316 Confidence: 100.0% Identity: 54% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase val144pro mutant from b. subtilis Phyre2 PDB 2yy5 chain C Region: 4 - 334 Aligned: 324 Modelled: 331 Confidence: 100.0% Identity: 40% PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from mycoplasma2 pneumoniae Phyre2 PDB 1yi8 chain C Region: 2 - 333 Aligned: 326 Modelled: 332 Confidence: 100.0% Identity: 30% PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl trrna synthetase ii from deinococcus2 radiodurans in complex with l-trp Phyre2 PDB 3m5w chain B Region: 3 - 330 Aligned: 318 Modelled: 323 Confidence: 100.0% Identity: 36% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 campylobacter jejuni Phyre2 PDB 2el7 chain A Region: 4 - 333 Aligned: 310 Modelled: 316 Confidence: 100.0% Identity: 41% PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from thermus2 thermophilus Phyre2 PDB 2g36 chain A Region: 5 - 331 Aligned: 313 Modelled: 324 Confidence: 100.0% Identity: 35% PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase (ec 6.1.1.2)2 (tryptophan-trna ligase)(trprs) (tm0492) from thermotoga maritima at3 2.50 a resolution Phyre2 PDB 2cyc chain B Region: 2 - 305 Aligned: 302 Modelled: 304 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with l-tyrosine2 from pyrococcus horikoshii Phyre2 PDB 2cyb chain A Region: 2 - 292 Aligned: 277 Modelled: 288 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with2 l-tyrosine from archaeoglobus fulgidus Phyre2 PDB 3a05 chain A Region: 2 - 297 Aligned: 277 Modelled: 284 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 hyperthermophilic archaeon, aeropyrum pernix k1 complex3 with tryptophan Phyre2 PDB 2qui chain B Region: 2 - 298 Aligned: 281 Modelled: 292 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structures of human tryptophanyl-trna synthetase in2 complex with tryptophanamide and atp Phyre2 PDB 3jxe chain B Region: 2 - 323 Aligned: 286 Modelled: 299 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii tryptophanyl-trna2 synthetase in complex with trpamp Phyre2 PDB 3p0j chain D Region: 2 - 307 Aligned: 296 Modelled: 298 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: leishmania major tyrosyl-trna synthetase in complex with tyrosinol,2 triclinic crystal form 1 Phyre2 PDB 2cya chain A Region: 2 - 305 Aligned: 280 Modelled: 294 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase from aeropyrum pernix Phyre2 PDB 3foc chain B Region: 2 - 298 Aligned: 280 Modelled: 297 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from giardia lamblia Phyre2 PDB 3hzr chain D Region: 2 - 298 Aligned: 278 Modelled: 297 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: D: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase homolog from entamoeba histolytica Phyre2 PDB 2j5b chain A Region: 2 - 307 Aligned: 274 Modelled: 290 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of the tyrosyl trna synthetase from acanthamoeba2 polyphaga mimivirus complexed with tyrosynol Phyre2 PDB 1r6t chain A domain 2 Region: 2 - 298 Aligned: 281 Modelled: 292 Confidence: 100.0% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 1 c3n9iA_ 2 c3sz3A_ 3 d1i6la_ 4 c3prhB_ 5 c2yy5C_ 6 c1yi8C_ 7 c3m5wB_ 8 c2el7A_ 9 c2g36A_ 10 c2cycB_ 11 c2cybA_ 12 c3a05A_ 13 c2quiB_ 14 c3jxeB_ 15 c3p0jD_ 16 c2cyaA_ 17 c3focB_ 18 c3hzrD_ 19 c2j5bA_ 20 d1r6ta2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3n9iA_ 100.0 86 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from yersinia pestis2 co92 2 c3sz3A_ 100.0 68 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from vibrio cholerae2 with an endogenous tryptophan 3 d1i6la_ 100.0 56 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 4 c3prhB_ 100.0 54 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase val144pro mutant from b. subtilis 5 c2yy5C_ 100.0 40 PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from mycoplasma2 pneumoniae 6 c1yi8C_ 100.0 30 PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl trrna synthetase ii from deinococcus2 radiodurans in complex with l-trp 7 c3m5wB_ 100.0 36 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 campylobacter jejuni 8 c2el7A_ 100.0 41 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from thermus2 thermophilus 9 c2g36A_ 100.0 35 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase (ec 6.1.1.2)2 (tryptophan-trna ligase)(trprs) (tm0492) from thermotoga maritima at3 2.50 a resolution 10 c2cycB_ 100.0 20 PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with l-tyrosine2 from pyrococcus horikoshii 11 c2cybA_ 100.0 22 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with2 l-tyrosine from archaeoglobus fulgidus 12 c3a05A_ 100.0 22 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 hyperthermophilic archaeon, aeropyrum pernix k1 complex3 with tryptophan 13 c2quiB_ 100.0 18 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structures of human tryptophanyl-trna synthetase in2 complex with tryptophanamide and atp 14 c3jxeB_ 100.0 20 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii tryptophanyl-trna2 synthetase in complex with trpamp 15 c3p0jD_ 100.0 18 PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: leishmania major tyrosyl-trna synthetase in complex with tyrosinol,2 triclinic crystal form 1 16 c2cyaA_ 100.0 20 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase from aeropyrum pernix 17 c3focB_ 100.0 20 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from giardia lamblia 18 c3hzrD_ 100.0 18 PDB header:ligase Chain: D: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase homolog from entamoeba histolytica 19 c2j5bA_ 100.0 22 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of the tyrosyl trna synthetase from acanthamoeba2 polyphaga mimivirus complexed with tyrosynol 20 d1r6ta2 100.0 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 21 c2dlcX_ not modelled 100.0 20 PDB header:ligase/trna Chain: X: PDB Molecule:tyrosyl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of the ternary complex of yeast tyrosyl-trna2 synthetase 22 c1q11A_ not modelled 100.0 17 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of an active fragment of human tyrosyl-trna2 synthetase with tyrosinol 23 d1n3la_ not modelled 100.0 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 24 c2ip1A_ not modelled 100.0 15 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure analysis of s. cerevisiae tryptophanyl trna2 synthetase 25 c1r6uB_ not modelled 100.0 15 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of an active fragment of human tryptophanyl-trna2 synthetase with cytokine activity 26 c3hv0A_ not modelled 100.0 19 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from cryptosporidium parvum 27 d2ts1a_ not modelled 100.0 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 28 c2ts1A_ not modelled 100.0 15 PDB header:ligase (synthetase) Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of tyrosyl-t/rna synthetase refined at 2.3 angstroms2 resolution. interaction of the enzyme with the tyrosyl adenylate3 intermediate 29 d1j1ua_ not modelled 100.0 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 30 c1jiiA_ not modelled 100.0 16 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of s. aureus tyrrs in complex with sb-219383 31 d1jila_ not modelled 100.0 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 32 c1x8xA_ not modelled 100.0 15 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl t-rna synthetase from e.coli complexed with tyrosine 33 c3i05B_ not modelled 100.0 21 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from trypanosoma brucei 34 c2rkjM_ not modelled 100.0 15 PDB header:ligase/rna Chain: M: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: cocrystal structure of a tyrosyl-trna synthetase splicing2 factor with a group i intron rna 35 d1h3fa1 not modelled 100.0 23 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 36 c1h3eA_ not modelled 100.0 21 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from thermus thermophilus complexed2 with wild-type trnatyr(gua) and with atp and tyrosinol 37 c2janD_ not modelled 100.0 16 PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from mycobacterium tuberculosis in2 unliganded state 38 c2pidB_ not modelled 100.0 15 PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of human mitochondrial tyrosyl-trna synthetase in2 complex with an adenylate analog 39 c3tqoA_ not modelled 98.7 13 PDB header:ligase Chain: A: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: structure of the cysteinyl-trna synthetase (cyss) from coxiella2 burnetii. 40 c2x1lC_ not modelled 98.7 19 PDB header:ligase Chain: C: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of mycobacterium smegmatis methionyl-trna2 synthetase in complex with methionine and adenosine 41 c2cfoA_ not modelled 98.5 26 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: non-discriminating glutamyl-trna synthetase from2 thermosynechococcus elongatus in complex with glu 42 c2ct8A_ not modelled 98.5 17 PDB header:ligase/rna Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of aquifex aeolicus methionyl-trna2 synthetase complexed with trna(met) and methionyl-adenylate3 anologue 43 d1li5a2 not modelled 98.4 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 44 c1u0bB_ not modelled 98.4 20 PDB header:ligase/rna Chain: B: PDB Molecule:cysteinyl trna; PDBTitle: crystal structure of cysteinyl-trna synthetase binary2 complex with trnacys 45 c3afhA_ not modelled 98.4 20 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase 2; PDBTitle: crystal structure of thermotoga maritima nondiscriminating glutamyl-2 trna synthetase in complex with a glutamyl-amp analog 46 d1gtra2 not modelled 98.4 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 47 c1g59A_ not modelled 98.3 21 PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: glutamyl-trna synthetase complexed with trna(glu). 48 d1pfva2 not modelled 98.3 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 49 c3al0C_ not modelled 98.2 19 PDB header:ligase/rna Chain: C: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit c, glutamyl- PDBTitle: crystal structure of the glutamine transamidosome from thermotoga2 maritima in the glutamylation state. 50 d1nzja_ not modelled 98.2 22 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 51 c2o5rA_ not modelled 98.1 17 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase 1; PDBTitle: crystal structure of glutamyl-trna synthetase 1 (ec 6.1.1.17)2 (glutamate-trna ligase 1) (glurs 1) (tm1351) from thermotoga maritima3 at 2.5 a resolution 52 d1f7ua2 not modelled 98.1 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 53 d1ivsa4 not modelled 98.0 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 54 d1ffya3 not modelled 98.0 23 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 55 d1j09a2 not modelled 98.0 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 56 c2ja2A_ not modelled 98.0 28 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: mycobacterium tuberculosis glutamyl-trna synthetase 57 c3aiiA_ not modelled 97.9 20 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: archaeal non-discriminating glutamyl-trna synthetase from2 methanothermobacter thermautotrophicus 58 c3c8zB_ not modelled 97.9 14 PDB header:ligase Chain: B: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: the 1.6 a crystal structure of mshc: the rate limiting2 enzyme in the mycothiol biosynthetic pathway 59 c3sp1B_ not modelled 97.9 14 PDB header:ligase Chain: B: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: crystal structure of cysteinyl-trna synthetase (cyss) from borrelia2 burgdorferi 60 c2hz7A_ not modelled 97.7 12 PDB header:ligase Chain: A: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of the glutaminyl-trna synthetase from2 deinococcus radiodurans 61 c3fnrA_ not modelled 97.7 15 PDB header:transferase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of putative arginyl t-rna synthetase from2 campylobacter jejuni; 62 c1exdA_ not modelled 97.7 14 PDB header:ligase/rna Chain: A: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of a tight-binding glutamine trna bound2 to glutamine aminoacyl trna synthetase 63 c1rqgA_ not modelled 97.4 10 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: methionyl-trna synthetase from pyrococcus abyssi 64 d1rqga2 not modelled 97.2 11 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 65 c1woyA_ not modelled 97.1 13 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of methionyl trna synthetase y225f mutant2 from thermus thermophilus 66 d1irxa2 not modelled 96.9 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 67 d2d5ba2 not modelled 96.9 12 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 68 c1pfuA_ not modelled 96.7 13 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: methionyl-trna synthetase from escherichia coli complexed2 with methionine phosphinate 69 c1irxA_ not modelled 96.7 28 PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of class i lysyl-trna synthetase 70 c3kflA_ not modelled 96.5 12 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: leishmania major methionyl-trna synthetase in complex with2 methionyladenylate and pyrophosphate 71 d1h3na3 not modelled 96.4 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 72 c1obhA_ not modelled 95.6 15 PDB header:synthetase Chain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site 73 c1gaxB_ not modelled 95.3 15 PDB header:ligase/rna Chain: B: PDB Molecule:valyl-trna synthetase; PDBTitle: crystal structure of thermus thermophilus valyl-trna2 synthetase complexed with trna(val) and valyl-adenylate3 analogue 74 c1wkbA_ not modelled 94.8 22 PDB header:ligase Chain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: crystal structure of leucyl-trna synthetase from the2 archaeon pyrococcus horikoshii reveals a novel editing3 domain orientation 75 c1qu2A_ not modelled 94.6 28 PDB header:ligase/rna Chain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: insights into editing from an ile-trna synthetase structure2 with trna(ile) and mupirocin 76 d1ilea3 not modelled 94.2 21 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 77 c1ileA_ not modelled 93.6 18 PDB header:aminoacyl-trna synthetase Chain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: isoleucyl-trna synthetase 78 d1iq0a2 not modelled 93.4 11 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 79 c2zufA_ not modelled 93.2 21 PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii arginyl-trna2 synthetase complexed with trna(arg) 80 c1wz2B_ not modelled 90.9 24 PDB header:ligase/rna Chain: B: PDB Molecule:leucyl-trna synthetase; PDBTitle: the crystal structure of leucyl-trna synthetase and trna(leucine)2 complex 81 c1f7uA_ not modelled 90.6 14 PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of the arginyl-trna synthetase complexed with the2 trna(arg) and l-arg 82 c1iq0A_ not modelled 89.1 12 PDB header:ligase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: thermus thermophilus arginyl-trna synthetase 83 c2r5wA_ not modelled 83.6 17 PDB header:hydrolase, transferase Chain: A: PDB Molecule:nicotinamide-nucleotide adenylyltransferase; PDBTitle: crystal structure of a bifunctional nmn2 adenylyltransferase/adp ribose pyrophosphatase from3 francisella tularensis 84 c1zuwA_ not modelled 72.2 19 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase 1; PDBTitle: crystal structure of b.subtilis glutamate racemase (race) with d-glu 85 c3e27B_ not modelled 71.6 9 PDB header:transferase Chain: B: PDB Molecule:nicotinate (nicotinamide) nucleotide PDBTitle: nicotinic acid mononucleotide (namn) adenylyltransferase2 from bacillus anthracis: product complex 86 c2ejcA_ not modelled 62.0 17 PDB header:ligase Chain: A: PDB Molecule:pantoate--beta-alanine ligase; PDBTitle: crystal structure of pantoate--beta-alanine ligase (panc)2 from thermotoga maritima 87 c3mxtA_ not modelled 55.8 18 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from campylobacter2 jejuni 88 d1auga_ not modelled 54.5 33 Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) 89 c2jfqA_ not modelled 47.6 19 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of staphylococcus aureus glutamate2 racemase in complex with d-glutamate 90 c3uk2B_ not modelled 44.8 13 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: the structure of pantothenate synthetase from burkholderia2 thailandensis 91 c2jfoB_ not modelled 40.9 19 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of enterococcus faecalis glutamate2 racemase in complex with d- and l-glutamate 92 d1v8fa_ not modelled 40.4 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 93 d1f0ka_ not modelled 39.0 14 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:Peptidoglycan biosynthesis glycosyltransferase MurG 94 c2gzmB_ not modelled 36.7 19 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of the glutamate racemase from bacillus2 anthracis 95 d1ihoa_ not modelled 31.0 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 96 c3n8hA_ not modelled 30.4 18 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from francisella2 tularensis 97 c3ag5A_ not modelled 28.5 25 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantothenate synthetase from staphylococcus2 aureus 98 c3innB_ not modelled 27.7 22 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine-ligase in complex2 with atp at low occupancy at 2.1 a resolution 99 c3guzB_ not modelled 26.6 13 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's 100 c3outC_ not modelled 25.7 20 PDB header:isomerase Chain: C: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase from francisella tularensis2 subsp. tularensis schu s4 in complex with d-glutamate. 101 d1htjf_ not modelled 24.2 13 Fold:Regulator of G-protein signaling, RGS Superfamily:Regulator of G-protein signaling, RGS Family:Regulator of G-protein signaling, RGS 102 c1htjF_ not modelled 24.2 13 PDB header:signaling protein Chain: F: PDB Molecule:kiaa0380; PDBTitle: structure of the rgs-like domain from pdz-rhogef 103 d1kgda_ not modelled 23.3 38 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nucleotide and nucleoside kinases 104 c2qjcA_ not modelled 23.2 10 PDB header:hydrolase Chain: A: PDB Molecule:diadenosine tetraphosphatase, putative; PDBTitle: crystal structure of a putative diadenosine tetraphosphatase 105 d1e6ca_ not modelled 22.9 41 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Shikimate kinase (AroK)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0