Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	D	K	L	T	S	L	R	Q	Y	T	T	V	V	A	D	T	G	D	I	A	A	M	K	L	Y	Q	P	Q	D	A	T	T	N	P	S	L	I	L	N	A	A	Q	I	P	E	Y	R	K	L	I	D	D	A	V	A	W	A	K
Secondary structure
SS confidence
Disorder		?	?	?																																												?											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	Q	S	N	D	R	A	Q	Q	I	V	D	A	T	D	K	L	A	V	N	I	G	L	E	I	L	K	L	V	P	G	R	I	S	T	E	V	D	A	R	L	S	Y	D	T	E	A	S	I	A	K	A	K	R	L	I	K	L	Y	N
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	A	G	I	S	N	D	R	I	L	I	K	L	A	S	T	W	Q	G	I	R	A	A	E	Q	L	E	K	E	G	I	N	C	N	L	T	L	L	F	S	F	A	Q	A	R	A	C	A	E	A	G	V	F	L	I	S	P	F	V	G
Secondary structure
SS confidence
Disorder			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	I	L	D	W	Y	K	A	N	T	D	K	K	E	Y	A	P	A	E	D	P	G	V	V	S	V	S	E	I	Y	Q	Y	Y	K	E	H	G	Y	E	T	V	V	M	G	A	S	F	R	N	I	G	E	I	L	E	L	A	G	C	D
Secondary structure
SS confidence
Disorder									?		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	L	T	I	A	P	A	L	L	K	E	L	A	E	S	E	G	A	I	E	R	K	L	S	Y	T	G	E	V	K	A	R	P	A	R	I	T	E	S	E	F	L	W	Q	H	N	Q	D	P	M	A	V	D	K	L	A	E	G	I	R
Secondary structure
SS confidence
Disorder																				?	?				?							?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.
Sequence		K	F	A	I	D	Q	E	K	L	E	K	M	I	G	D	L	L
Secondary structure
SS confidence
Disorder																	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1onr chain A Region: 2 - 317 Aligned: 316 Modelled: 316 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1f05 chain A Region: 1 - 317 Aligned: 317 Modelled: 317 Confidence: 100.0% Identity: 60% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 2e1d chain A domain 1 Region: 3 - 317 Aligned: 315 Modelled: 315 Confidence: 100.0% Identity: 60% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3m16 chain A Region: 2 - 317 Aligned: 316 Modelled: 316 Confidence: 100.0% Identity: 61% PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: structure of a transaldolase from oleispira antarctica Phyre2 PDB 3igx chain A Region: 3 - 317 Aligned: 315 Modelled: 315 Confidence: 100.0% Identity: 48% PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: 1.85 angstrom resolution crystal structure of transaldolase b (tala)2 from francisella tularensis. Phyre2 PDB 3hjz chain A Region: 2 - 317 Aligned: 316 Modelled: 316 Confidence: 100.0% Identity: 53% PDB header:transferase Chain: A: PDB Molecule:transaldolase b; PDBTitle: the structure of an aldolase from prochlorococcus marinus Phyre2 PDB 3cq0 chain B Region: 2 - 317 Aligned: 310 Modelled: 316 Confidence: 100.0% Identity: 53% PDB header:transferase Chain: B: PDB Molecule:putative transaldolase ygr043c; PDBTitle: crystal structure of tal2_yeast Phyre2 PDB 3clm chain A Region: 2 - 313 Aligned: 300 Modelled: 311 Confidence: 100.0% Identity: 23% PDB header:lyase Chain: A: PDB Molecule:transaldolase; PDBTitle: crystal structure of transaldolase (yp_208650.1) from neisseria2 gonorrhoeae fa 1090 at 1.14 a resolution Phyre2 PDB 3s1v chain D Region: 13 - 309 Aligned: 208 Modelled: 211 Confidence: 100.0% Identity: 37% PDB header:transferase Chain: D: PDB Molecule:probable transaldolase; PDBTitle: transaldolase from thermoplasma acidophilum in complex with d-fructose2 6-phosphate schiff-base intermediate Phyre2 PDB 1wx0 chain A domain 1 Region: 13 - 258 Aligned: 200 Modelled: 203 Confidence: 100.0% Identity: 32% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1vpx chain A Region: 13 - 311 Aligned: 196 Modelled: 199 Confidence: 100.0% Identity: 39% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1l6w chain A Region: 13 - 309 Aligned: 207 Modelled: 219 Confidence: 100.0% Identity: 30% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1xm3 chain A Region: 134 - 250 Aligned: 101 Modelled: 102 Confidence: 96.0% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: ThiG-like Family: ThiG-like Phyre2 PDB 2htm chain B Region: 133 - 249 Aligned: 102 Modelled: 102 Confidence: 95.0% Identity: 18% PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 Phyre2 PDB 2p10 chain D Region: 140 - 224 Aligned: 72 Modelled: 85 Confidence: 92.5% Identity: 17% PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution Phyre2 PDB 1o4u chain A domain 1 Region: 114 - 245 Aligned: 110 Modelled: 111 Confidence: 87.2% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 1o4u chain A Region: 134 - 245 Aligned: 90 Modelled: 91 Confidence: 85.1% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution Phyre2 PDB 2p10 chain A domain 1 Region: 140 - 180 Aligned: 40 Modelled: 41 Confidence: 84.8% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Mll9387-like Phyre2 PDB 3lab chain A Region: 102 - 246 Aligned: 114 Modelled: 122 Confidence: 83.8% Identity: 24% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica Phyre2 PDB 3gk0 chain H Region: 84 - 188 Aligned: 90 Modelled: 105 Confidence: 80.6% Identity: 28% PDB header:transferase Chain: H: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic2 protein from burkholderia pseudomallei Phyre2 1 d1onra_ 2 d1f05a_ 3 d2e1da1 4 c3m16A_ 5 c3igxA_ 6 c3hjzA_ 7 c3cq0B_ 8 c3clmA_ 9 c3s1vD_ 10 d1wx0a1 11 d1vpxa_ 12 d1l6wa_ 13 d1xm3a_ 14 c2htmB_ 15 c2p10D_ 16 d1o4ua1 17 c1o4uA_ 18 d2p10a1 19 c3labA_ 20 c3gk0H_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1onra_ 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 2 d1f05a_ 100.0 60 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 3 d2e1da1 100.0 60 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 4 c3m16A_ 100.0 61 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: structure of a transaldolase from oleispira antarctica 5 c3igxA_ 100.0 48 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: 1.85 angstrom resolution crystal structure of transaldolase b (tala)2 from francisella tularensis. 6 c3hjzA_ 100.0 53 PDB header:transferase Chain: A: PDB Molecule:transaldolase b; PDBTitle: the structure of an aldolase from prochlorococcus marinus 7 c3cq0B_ 100.0 53 PDB header:transferase Chain: B: PDB Molecule:putative transaldolase ygr043c; PDBTitle: crystal structure of tal2_yeast 8 c3clmA_ 100.0 23 PDB header:lyase Chain: A: PDB Molecule:transaldolase; PDBTitle: crystal structure of transaldolase (yp_208650.1) from neisseria2 gonorrhoeae fa 1090 at 1.14 a resolution 9 c3s1vD_ 100.0 37 PDB header:transferase Chain: D: PDB Molecule:probable transaldolase; PDBTitle: transaldolase from thermoplasma acidophilum in complex with d-fructose2 6-phosphate schiff-base intermediate 10 d1wx0a1 100.0 32 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 11 d1vpxa_ 100.0 39 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 12 d1l6wa_ 100.0 30 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 13 d1xm3a_ 96.0 19 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 14 c2htmB_ 95.0 18 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 15 c2p10D_ 92.5 17 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 16 d1o4ua1 87.2 15 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 17 c1o4uA_ 85.1 13 PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution 18 d2p10a1 84.8 23 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Mll9387-like 19 c3labA_ 83.8 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 20 c3gk0H_ 80.6 28 PDB header:transferase Chain: H: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic2 protein from burkholderia pseudomallei 21 d1ea0a2 not modelled 77.6 25 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 22 d1m5wa_ not modelled 75.8 21 Fold:TIM beta/alpha-barrel Superfamily:Pyridoxine 5'-phosphate synthase Family:Pyridoxine 5'-phosphate synthase 23 d1o66a_ not modelled 72.1 26 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 24 c3ez4B_ not modelled 70.4 17 PDB header:transferase Chain: B: PDB Molecule:3-methyl-2-oxobutanoate hydroxymethyltransferase; PDBTitle: crystal structure of 3-methyl-2-oxobutanoate2 hydroxymethyltransferase from burkholderia pseudomallei 25 c2jbmA_ not modelled 70.0 19 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human 26 c3o6cA_ not modelled 69.0 16 PDB header:transferase Chain: A: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: pyridoxal phosphate biosynthetic protein pdxj from campylobacter2 jejuni 27 d1nkua_ not modelled 65.8 23 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:3-Methyladenine DNA glycosylase I (Tag) 28 d1wa3a1 not modelled 64.3 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 29 d1nu5a1 not modelled 64.1 18 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 30 d1ofda2 not modelled 64.0 24 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 31 d1cjca2 not modelled 62.0 19 Fold:Nucleotide-binding domain Superfamily:Nucleotide-binding domain Family:N-terminal domain of adrenodoxin reductase-like 32 d1kbia1 not modelled 60.9 21 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 33 c2yw3E_ not modelled 60.8 25 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 34 d1wbha1 not modelled 59.4 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 35 c3oa3A_ not modelled 59.4 20 PDB header:lyase Chain: A: PDB Molecule:aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis 36 c2p0iA_ not modelled 59.0 14 PDB header:lyase Chain: A: PDB Molecule:l-rhamnonate dehydratase; PDBTitle: crystal structure of l-rhamnonate dehydratase from gibberella zeae 37 c2hxtA_ not modelled 58.1 16 PDB header:unknown function Chain: A: PDB Molecule:l-fuconate dehydratase; PDBTitle: crystal structure of l-fuconate dehydratase from xanthomonas2 campestris liganded with mg++ and d-erythronohydroxamate 38 d1mzha_ not modelled 56.1 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 39 c2jg6A_ not modelled 55.7 20 PDB header:hydrolase Chain: A: PDB Molecule:dna-3-methyladenine glycosidase; PDBTitle: crystal structure of a 3-methyladenine dna glycosylase i2 from staphylococcus aureus 40 c2b7pA_ not modelled 54.2 18 PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori 41 d1wv2a_ not modelled 52.8 21 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 42 c1kbiB_ not modelled 52.3 21 PDB header:oxidoreductase Chain: B: PDB Molecule:cytochrome b2; PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme 43 c3ffsC_ not modelled 50.8 16 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 44 d1pv8a_ not modelled 50.6 22 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 45 d1iyna_ not modelled 50.5 21 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:CCP-like 46 c3pajA_ not modelled 49.6 13 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 47 c1zfjA_ not modelled 49.6 23 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 48 c1lm1A_ not modelled 49.4 22 PDB header:oxidoreductase Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase; PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme 49 c1cjcA_ not modelled 46.3 19 PDB header:oxidoreductase Chain: A: PDB Molecule:protein (adrenodoxin reductase); PDBTitle: structure of adrenodoxin reductase of mitochondrial p4502 systems 50 c3cxoA_ not modelled 43.6 17 PDB header:lyase Chain: A: PDB Molecule:putative galactonate dehydratase; PDBTitle: crystal structure of l-rhamnonate dehydratase from2 salmonella typhimurium complexed with mg and 3-deoxy-l-3 rhamnonate 51 d2euta1 not modelled 43.5 23 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:CCP-like 52 c3rcyC_ not modelled 42.7 13 PDB header:isomerase Chain: C: PDB Molecule:mandelate racemase/muconate lactonizing enzyme-like PDBTitle: crystal structure of mandelate racemase/muconate lactonizing enzyme-2 like protein from roseovarius sp. tm1035 53 c2v3aA_ not modelled 40.7 16 PDB header:oxidoreductase Chain: A: PDB Molecule:rubredoxin reductase; PDBTitle: crystal structure of rubredoxin reductase from pseudomonas2 aeruginosa. 54 d1j5ta_ not modelled 40.1 21 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 55 d1vc4a_ not modelled 40.0 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 56 d1vhna_ not modelled 39.9 24 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 57 d1eepa_ not modelled 39.7 17 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 58 d1d7ya2 not modelled 39.6 21 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 59 c2oz3F_ not modelled 39.6 15 PDB header:lyase Chain: F: PDB Molecule:mandelate racemase/muconate lactonizing enzyme; PDBTitle: crystal structure of l-rhamnonate dehydratase from azotobacter2 vinelandii 60 d1vhca_ not modelled 39.1 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 61 c3l0gD_ not modelled 37.1 23 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 62 c3ef6A_ not modelled 37.1 23 PDB header:oxidoreductase Chain: A: PDB Molecule:toluene 1,2-dioxygenase system ferredoxin--nad(+) PDBTitle: crystal structure of toluene 2,3-dioxygenase reductase 63 d1bd3a_ not modelled 37.0 10 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 64 d1p0ka_ not modelled 36.6 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 65 c3dg7B_ not modelled 36.2 14 PDB header:isomerase Chain: B: PDB Molecule:muconate cycloisomerase; PDBTitle: crystal structure of muconate lactonizing enzyme from mucobacterium2 smegmatis complexed with muconolactone 66 d2e39a1 not modelled 35.8 18 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:CCP-like 67 d1mxsa_ not modelled 35.7 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 68 c3n4eA_ not modelled 35.4 14 PDB header:isomerase Chain: A: PDB Molecule:mandelate racemase/muconate lactonizing enzyme, c-terminal PDBTitle: crystal structure of mandelate racemase/muconate lactonizing protein2 from paracoccus denitrificans pd1222 69 c3llvA_ not modelled 35.0 10 PDB header:nad(p) binding protein Chain: A: PDB Molecule:exopolyphosphatase-related protein; PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a 70 c3gr7A_ not modelled 34.8 14 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 71 c2gr2A_ not modelled 34.5 13 PDB header:oxidoreductase Chain: A: PDB Molecule:ferredoxin reductase; PDBTitle: crystal structure of ferredoxin reductase, bpha4 (oxidized form) 72 d1qpoa1 not modelled 33.4 12 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 73 c2v82A_ not modelled 33.1 23 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 74 c2qq6B_ not modelled 32.2 12 PDB header:isomerase Chain: B: PDB Molecule:mandelate racemase/muconate lactonizing enzyme- PDBTitle: crystal structure of mandelate racemase/muconate2 lactonizing enzyme-like protein from rubrobacter3 xylanophilus dsm 9941 75 c3gkaB_ not modelled 32.2 14 PDB header:oxidoreductase Chain: B: PDB Molecule:n-ethylmaleimide reductase; PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei 76 d1vyra_ not modelled 32.1 13 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 77 c2pp1C_ not modelled 31.5 17 PDB header:lyase Chain: C: PDB Molecule:l-talarate/galactarate dehydratase; PDBTitle: crystal structure of l-talarate/galactarate dehydratase from2 salmonella typhimurium lt2 liganded with mg and l-lyxarohydroxamate 78 c1x1oC_ not modelled 30.7 16 PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 79 d2gdqa1 not modelled 30.5 17 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 80 c2ox4E_ not modelled 29.8 17 PDB header:isomerase Chain: E: PDB Molecule:putative mandelate racemase; PDBTitle: crystal structure of putative dehydratase from zymomonas mobilis zm4 81 d1z41a1 not modelled 29.5 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 82 c3hyxC_ not modelled 29.0 19 PDB header:oxidoreductase Chain: C: PDB Molecule:sulfide-quinone reductase; PDBTitle: 3-d x-ray structure of the sulfide:quinone oxidoreductase from aquifex2 aeolicus in complex with aurachin c 83 c3px5A_ not modelled 28.5 14 PDB header:metal binding protein Chain: A: PDB Molecule:enzyme of enolase superfamily; PDBTitle: structure of efi enolase target en500555, a putative dipeptide2 epimerase: apo structure 84 c3q3uA_ not modelled 28.4 16 PDB header:oxidoreductase Chain: A: PDB Molecule:lignin peroxidase; PDBTitle: trametes cervina lignin peroxidase 85 c2vdcF_ not modelled 28.1 24 PDB header:oxidoreductase Chain: F: PDB Molecule:glutamate synthase [nadph] large chain; PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications. 86 c3t6cB_ not modelled 27.5 13 PDB header:lyase Chain: B: PDB Molecule:putative mand family dehydratase; PDBTitle: crystal structure of an enolase from pantoea ananatis (efi target efi-2 501676) with bound d-gluconate and mg 87 c3riwA_ not modelled 27.3 21 PDB header:oxidoreductase Chain: A: PDB Molecule:ascorbate peroxidase; PDBTitle: the crystal structure of leishmania major peroxidase mutant c197t 88 d2dw4a2 not modelled 27.1 27 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 89 d1n7ka_ not modelled 27.0 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 90 d1goxa_ not modelled 27.0 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 91 c1tv5A_ not modelled 26.8 14 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial; PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor 92 d1tv5a1 not modelled 26.8 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 93 d1i5za1 not modelled 26.7 25 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:CAP C-terminal domain-like 94 c1qpoA_ not modelled 26.7 12 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 95 c3lxdA_ not modelled 26.7 18 PDB header:oxidoreductase Chain: A: PDB Molecule:fad-dependent pyridine nucleotide-disulphide PDBTitle: crystal structure of ferredoxin reductase arr from novosphingobium2 aromaticivorans 96 d1f61a_ not modelled 26.2 13 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 97 c2rusB_ not modelled 26.0 19 PDB header:lyase(carbon-carbon) Chain: B: PDB Molecule:rubisco (ribulose-1,5-bisphosphate PDBTitle: crystal structure of the ternary complex of ribulose-1,5-2 bisphosphate carboxylase, mg(ii), and activator co2 at 2.3-3 angstroms resolution 98 c3fg2P_ not modelled 25.8 25 PDB header:oxidoreductase Chain: P: PDB Molecule:putative rubredoxin reductase; PDBTitle: crystal structure of ferredoxin reductase for the cyp199a2 system from2 rhodopseudomonas palustris 99 c1qapA_ not modelled 25.8 12 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 100 c3fwzA_ not modelled 25.6 10 PDB header:membrane protein Chain: A: PDB Molecule:inner membrane protein ybal; PDBTitle: crystal structure of trka-n domain of inner membrane protein ybal from2 escherichia coli 101 c3h12B_ not modelled 25.3 13 PDB header:isomerase Chain: B: PDB Molecule:mandelate racemase; PDBTitle: crystal structure of putative mandelate racemase from bordetella2 bronchiseptica rb50 102 d1vkfa_ not modelled 25.3 19 Fold:TIM beta/alpha-barrel Superfamily:GlpP-like Family:GlpP-like 103 c3bw2A_ not modelled 25.1 20 PDB header:oxidoreductase Chain: A: PDB Molecule:2-nitropropane dioxygenase; PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes 104 c1yqzA_ not modelled 25.0 13 PDB header:oxidoreductase Chain: A: PDB Molecule:coenzyme a disulfide reductase; PDBTitle: structure of coenzyme a-disulfide reductase from2 staphylococcus aureus refined at 1.54 angstrom resolution 105 c2ehjA_ not modelled 24.5 18 PDB header:transferase Chain: A: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of uracil phosphoribosyl transferase 106 c1q1wA_ not modelled 24.2 27 PDB header:oxidoreductase Chain: A: PDB Molecule:putidaredoxin reductase; PDBTitle: crystal structure of putidaredoxin reductase from2 pseudomonas putida 107 d1nhpa2 not modelled 24.1 24 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 108 d1itza3 not modelled 24.0 27 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Transketolase C-terminal domain-like 109 c2zrvC_ not modelled 23.8 17 PDB header:isomerase Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase; PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn. 110 d1tb3a1 not modelled 23.8 23 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 111 c3ivuB_ not modelled 23.8 25 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 112 d1uuma_ not modelled 23.7 19 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 113 d1o5oa_ not modelled 23.7 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 114 c3sqsA_ not modelled 23.5 7 PDB header:isomerase Chain: A: PDB Molecule:mandelate racemase/muconate lactonizing protein; PDBTitle: crystal structure of a putative mandelate racemase/muconate2 lactonizing protein from dinoroseobacter shibae dfl 12 115 c1rcxH_ not modelled 23.4 21 PDB header:lyase (carbon-carbon) Chain: H: PDB Molecule:ribulose bisphosphate carboxylase/oxygenase; PDBTitle: non-activated spinach rubisco in complex with its substrate2 ribulose-1,5-bisphosphate 116 d1p4ca_ not modelled 23.1 23 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 117 d2chra1 not modelled 22.7 16 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 118 d1v9sa1 not modelled 22.7 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 119 c1me9A_ not modelled 22.6 15 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound 120 d2gl5a1 not modelled 21.9 13 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0