Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	N	N	T	T	A	P	T	Y	T	L	R	G	L	Q	L	I	G	W	R	D	M	Q	H	A	L	D	Y	L	F	A	D	G	Q	L	K	Q	G	T	L	V	A	I	N	A	E	K	M	L	T	I	E	D	N	A	E	V	R	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	I	N	A	A	E	F	K	Y	A	D	G	I	S	V	V	R	S	V	R	K	K	Y	P	Q	A	Q	V	S	R	V	A	G	A	D	L	W	E	E	L	M	A	R	A	G	K	E	G	T	P	V	F	L	V	G	G	K	P	E	V
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	Q	T	E	A	K	L	R	N	Q	W	N	V	N	I	V	G	S	Q	D	G	Y	F	K	P	E	Q	R	Q	A	L	F	E	R	I	H	A	S	G	A	Q	I	V	T	V	A	M	G	S	P	K	Q	E	I	I	M	R	D	C
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	L	V	H	P	D	A	L	Y	M	G	V	G	G	T	Y	D	V	F	T	G	H	V	K	R	A	P	K	I	W	Q	T	L	G	L	E	W	L	Y	R	L	L	S	Q	P	S	R	I	K	R	Q	L	R	L	L	R	Y	L	R	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.
Sequence		H	Y	T	G	N	L
Secondary structure
SS confidence
Disorder				?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3i09 chain A Region: 92 - 194 Aligned: 103 Modelled: 103 Confidence: 95.8% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:periplasmic branched-chain amino acid-binding protein; PDBTitle: crystal structure of a periplasmic binding protein (bma2936) from2 burkholderia mallei at 1.80 a resolution Phyre2 PDB 3sg0 chain A Region: 92 - 197 Aligned: 106 Modelled: 106 Confidence: 95.0% Identity: 11% PDB header:signaling protein Chain: A: PDB Molecule:extracellular ligand-binding receptor; PDBTitle: the crystal structure of an extracellular ligand-binding receptor from2 rhodopseudomonas palustris haa2 Phyre2 PDB 1t1r chain A domain 2 Region: 109 - 200 Aligned: 88 Modelled: 92 Confidence: 93.2% Identity: 10% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 3lop chain A Region: 92 - 197 Aligned: 106 Modelled: 106 Confidence: 93.0% Identity: 8% PDB header:substrate binding protein Chain: A: PDB Molecule:substrate binding periplasmic protein; PDBTitle: crystal structure of substrate-binding periplasmic protein2 (pbp) from ralstonia solanacearum Phyre2 PDB 3n0w chain A Region: 92 - 183 Aligned: 92 Modelled: 92 Confidence: 91.9% Identity: 18% PDB header:transport protein Chain: A: PDB Molecule:abc branched chain amino acid family transporter, PDBTitle: crystal structure of a branched chain amino acid abc transporter2 periplasmic ligand-binding protein (bxe_c0949) from burkholderia3 xenovorans lb400 at 1.88 a resolution Phyre2 PDB 3lkb chain B Region: 92 - 197 Aligned: 106 Modelled: 106 Confidence: 91.8% Identity: 18% PDB header:transport protein Chain: B: PDB Molecule:probable branched-chain amino acid abc PDBTitle: crystal structure of a branched chain amino acid abc2 transporter from thermus thermophilus with bound valine Phyre2 PDB 3h5l chain B Region: 97 - 197 Aligned: 101 Modelled: 101 Confidence: 89.3% Identity: 6% PDB header:transport protein Chain: B: PDB Molecule:putative branched-chain amino acid abc PDBTitle: crystal structure of a putative branched-chain amino acid2 abc transporter from silicibacter pomeroyi Phyre2 PDB 3nkl chain A Region: 107 - 204 Aligned: 97 Modelled: 98 Confidence: 89.1% Identity: 15% PDB header:oxidoreductase/lyase Chain: A: PDB Molecule:udp-d-quinovosamine 4-dehydrogenase; PDBTitle: crystal structure of udp-d-quinovosamine 4-dehydrogenase from vibrio2 fischeri Phyre2 PDB 3snr chain A Region: 92 - 197 Aligned: 106 Modelled: 106 Confidence: 86.8% Identity: 12% PDB header:transport protein Chain: A: PDB Molecule:extracellular ligand-binding receptor; PDBTitle: rpd_1889 protein, an extracellular ligand-binding receptor from2 rhodopseudomonas palustris. Phyre2 PDB 2eyq chain A domain 5 Region: 95 - 166 Aligned: 72 Modelled: 72 Confidence: 86.8% Identity: 11% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Tandem AAA-ATPase domain Phyre2 PDB 1usg chain A Region: 15 - 197 Aligned: 177 Modelled: 183 Confidence: 86.7% Identity: 12% Fold: Periplasmic binding protein-like I Superfamily: Periplasmic binding protein-like I Family: L-arabinose binding protein-like Phyre2 PDB 3ip5 chain A Region: 107 - 197 Aligned: 91 Modelled: 91 Confidence: 86.1% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:abc transporter, substrate binding protein (amino acid); PDBTitle: structure of atu2422-gaba receptor in complex with alanine Phyre2 PDB 1a2o chain B Region: 107 - 193 Aligned: 81 Modelled: 87 Confidence: 85.2% Identity: 11% PDB header:bacterial chemotaxis Chain: B: PDB Molecule:cheb methylesterase; PDBTitle: structural basis for methylesterase cheb regulation by a2 phosphorylation-activated domain Phyre2 PDB 1k5h chain B Region: 109 - 167 Aligned: 55 Modelled: 59 Confidence: 83.5% Identity: 13% PDB header:oxidoreductase Chain: B: PDB Molecule:1-deoxy-d-xylulose-5-phosphate reductoisomerase; PDBTitle: 1-deoxy-d-xylulose-5-phosphate reductoisomerase Phyre2 PDB 1y80 chain A Region: 93 - 213 Aligned: 103 Modelled: 121 Confidence: 83.0% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted cobalamin binding protein; PDBTitle: structure of a corrinoid (factor iiim)-binding protein from2 moorella thermoacetica Phyre2 PDB 2ozp chain A Region: 108 - 196 Aligned: 87 Modelled: 89 Confidence: 82.1% Identity: 9% PDB header:oxidoreductase Chain: A: PDB Molecule:n-acetyl-gamma-glutamyl-phosphate reductase; PDBTitle: crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase2 (ttha1904) from thermus thermophilus Phyre2 PDB 2q49 chain A domain 1 Region: 107 - 198 Aligned: 89 Modelled: 92 Confidence: 81.7% Identity: 12% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 1vkn chain A domain 1 Region: 108 - 198 Aligned: 87 Modelled: 90 Confidence: 80.0% Identity: 10% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 1qo0 chain A Region: 92 - 197 Aligned: 106 Modelled: 106 Confidence: 79.6% Identity: 14% Fold: Periplasmic binding protein-like I Superfamily: Periplasmic binding protein-like I Family: L-arabinose binding protein-like Phyre2 PDB 1ys4 chain A Region: 107 - 209 Aligned: 101 Modelled: 102 Confidence: 79.1% Identity: 13% PDB header:oxidoreductase Chain: A: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: structure of aspartate-semialdehyde dehydrogenase from2 methanococcus jannaschii Phyre2 PDB 3hsk chain B Region: 109 - 227 Aligned: 117 Modelled: 117 Confidence: 78.7% Identity: 9% PDB header:oxidoreductase Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase2 with nadp from candida albicans Phyre2 1 c3i09A_ 2 c3sg0A_ 3 d1t1ra2 4 c3lopA_ 5 c3n0wA_ 6 c3lkbB_ 7 c3h5lB_ 8 c3nklA_ 9 c3snrA_ 10 d2eyqa5 11 d1usga_ 12 c3ip5A_ 13 c1a2oB_ 14 c1k5hB_ 15 c1y80A_ 16 c2ozpA_ 17 d2q49a1 18 d1vkna1 19 d1qo0a_ 20 c1ys4A_ 21 22 c3hskB_ 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3i09A_ 95.8 11 PDB header:transport protein Chain: A: PDB Molecule:periplasmic branched-chain amino acid-binding protein; PDBTitle: crystal structure of a periplasmic binding protein (bma2936) from2 burkholderia mallei at 1.80 a resolution 2 c3sg0A_ 95.0 11 PDB header:signaling protein Chain: A: PDB Molecule:extracellular ligand-binding receptor; PDBTitle: the crystal structure of an extracellular ligand-binding receptor from2 rhodopseudomonas palustris haa2 3 d1t1ra2 93.2 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 4 c3lopA_ 93.0 8 PDB header:substrate binding protein Chain: A: PDB Molecule:substrate binding periplasmic protein; PDBTitle: crystal structure of substrate-binding periplasmic protein2 (pbp) from ralstonia solanacearum 5 c3n0wA_ 91.9 18 PDB header:transport protein Chain: A: PDB Molecule:abc branched chain amino acid family transporter, PDBTitle: crystal structure of a branched chain amino acid abc transporter2 periplasmic ligand-binding protein (bxe_c0949) from burkholderia3 xenovorans lb400 at 1.88 a resolution 6 c3lkbB_ 91.8 18 PDB header:transport protein Chain: B: PDB Molecule:probable branched-chain amino acid abc PDBTitle: crystal structure of a branched chain amino acid abc2 transporter from thermus thermophilus with bound valine 7 c3h5lB_ 89.3 6 PDB header:transport protein Chain: B: PDB Molecule:putative branched-chain amino acid abc PDBTitle: crystal structure of a putative branched-chain amino acid2 abc transporter from silicibacter pomeroyi 8 c3nklA_ 89.1 15 PDB header:oxidoreductase/lyase Chain: A: PDB Molecule:udp-d-quinovosamine 4-dehydrogenase; PDBTitle: crystal structure of udp-d-quinovosamine 4-dehydrogenase from vibrio2 fischeri 9 c3snrA_ 86.8 12 PDB header:transport protein Chain: A: PDB Molecule:extracellular ligand-binding receptor; PDBTitle: rpd_1889 protein, an extracellular ligand-binding receptor from2 rhodopseudomonas palustris. 10 d2eyqa5 86.8 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 11 d1usga_ 86.7 12 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 12 c3ip5A_ 86.1 14 PDB header:transport protein Chain: A: PDB Molecule:abc transporter, substrate binding protein (amino acid); PDBTitle: structure of atu2422-gaba receptor in complex with alanine 13 c1a2oB_ 85.2 11 PDB header:bacterial chemotaxis Chain: B: PDB Molecule:cheb methylesterase; PDBTitle: structural basis for methylesterase cheb regulation by a2 phosphorylation-activated domain 14 c1k5hB_ 83.5 13 PDB header:oxidoreductase Chain: B: PDB Molecule:1-deoxy-d-xylulose-5-phosphate reductoisomerase; PDBTitle: 1-deoxy-d-xylulose-5-phosphate reductoisomerase 15 c1y80A_ 83.0 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted cobalamin binding protein; PDBTitle: structure of a corrinoid (factor iiim)-binding protein from2 moorella thermoacetica 16 c2ozpA_ 82.1 9 PDB header:oxidoreductase Chain: A: PDB Molecule:n-acetyl-gamma-glutamyl-phosphate reductase; PDBTitle: crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase2 (ttha1904) from thermus thermophilus 17 d2q49a1 81.7 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 18 d1vkna1 80.0 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 19 d1qo0a_ 79.6 14 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 20 c1ys4A_ 79.1 13 PDB header:oxidoreductase Chain: A: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: structure of aspartate-semialdehyde dehydrogenase from2 methanococcus jannaschii 21 d2liva_ not modelled 79.0 15 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 22 c3hskB_ 78.7 9 PDB header:oxidoreductase Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase2 with nadp from candida albicans 23 d3bula2 not modelled 78.2 8 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 24 c2gwrA_ not modelled 77.7 12 PDB header:signaling protein Chain: A: PDB Molecule:dna-binding response regulator mtra; PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis 25 c3hutA_ not modelled 76.8 13 PDB header:transport protein Chain: A: PDB Molecule:putative branched-chain amino acid abc PDBTitle: crystal structure of a putative branched-chain amino acid2 abc transporter from rhodospirillum rubrum 26 c2eyqA_ not modelled 76.6 11 PDB header:hydrolase Chain: A: PDB Molecule:transcription-repair coupling factor; PDBTitle: crystal structure of escherichia coli transcription-repair2 coupling factor 27 c2g17A_ not modelled 74.9 10 PDB header:oxidoreductase Chain: A: PDB Molecule:n-acetyl-gamma-glutamyl-phosphate reductase; PDBTitle: the structure of n-acetyl-gamma-glutamyl-phosphate reductase from2 salmonella typhimurium. 28 c3eulB_ not modelled 74.7 18 PDB header:transcription Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis 29 d2a9pa1 not modelled 74.5 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 30 c3f6cB_ not modelled 74.0 13 PDB header:dna binding protein Chain: B: PDB Molecule:positive transcription regulator evga; PDBTitle: crystal structure of n-terminal domain of positive transcription2 regulator evga from escherichia coli 31 c2eghA_ not modelled 72.7 11 PDB header:oxidoreductase Chain: A: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase2 complexed with a magnesium ion, nadph and fosmidomycin 32 c2zwmA_ not modelled 72.1 14 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulatory protein yycf; PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis 33 c3eafA_ not modelled 72.1 14 PDB header:transport protein Chain: A: PDB Molecule:abc transporter, substrate binding protein; PDBTitle: crystal structure of abc transporter, substrate binding protein2 aeropyrum pernix 34 d1r0ka2 not modelled 71.8 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 35 c3rfuC_ not modelled 71.4 13 PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:copper efflux atpase; PDBTitle: crystal structure of a copper-transporting pib-type atpase 36 c1t4bB_ not modelled 70.9 11 PDB header:oxidoreductase Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: 1.6 angstrom structure of esherichia coli aspartate-2 semialdehyde dehydrogenase. 37 c2gz3D_ not modelled 70.6 15 PDB header:oxidoreductase Chain: D: PDB Molecule:aspartate beta-semialdehyde dehydrogenase; PDBTitle: structure of aspartate semialdehyde dehydrogenase (asadh) from2 streptococcus pneumoniae complexed with nadp and aspartate-3 semialdehyde 38 c3b2nA_ not modelled 70.1 10 PDB header:transcription Chain: A: PDB Molecule:uncharacterized protein q99uf4; PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus 39 c3n0xA_ not modelled 70.0 7 PDB header:transport protein Chain: A: PDB Molecule:possible substrate binding protein of abc transporter PDBTitle: crystal structure of an abc-type branched-chain amino acid transporter2 (rpa4397) from rhodopseudomonas palustris cga009 at 1.50 a resolution 40 d2gz1a1 not modelled 69.3 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 41 c2yxbA_ not modelled 68.2 9 PDB header:isomerase Chain: A: PDB Molecule:coenzyme b12-dependent mutase; PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix 42 c3nhzA_ not modelled 67.7 13 PDB header:dna binding protein Chain: A: PDB Molecule:two component system transcriptional regulator mtra; PDBTitle: structure of n-terminal domain of mtra 43 c2q5cA_ not modelled 67.5 10 PDB header:transcription Chain: A: PDB Molecule:ntrc family transcriptional regulator; PDBTitle: crystal structure of ntrc family transcriptional regulator from2 clostridium acetobutylicum 44 d2hjsa1 not modelled 67.4 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 45 d1u0sy_ not modelled 67.2 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 46 c1r0lD_ not modelled 66.7 11 PDB header:oxidoreductase Chain: D: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: 1-deoxy-d-xylulose 5-phosphate reductoisomerase from2 zymomonas mobilis in complex with nadph 47 d2pjua1 not modelled 66.7 19 Fold:Chelatase-like Superfamily:PrpR receptor domain-like Family:PrpR receptor domain-like 48 d2g17a1 not modelled 65.5 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 49 c1mb4B_ not modelled 65.5 14 PDB header:oxidoreductase Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase2 from vibrio cholerae with nadp and s-methyl-l-cysteine3 sulfoxide 50 d1dz3a_ not modelled 65.4 11 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 51 c3sajB_ not modelled 64.3 11 PDB header:transport protein Chain: B: PDB Molecule:glutamate receptor 1; PDBTitle: crystal structure of glutamate receptor glua1 amino terminal domain 52 d1xhfa1 not modelled 63.9 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 53 d1vl0a_ not modelled 62.8 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 54 c2pjuD_ not modelled 62.3 18 PDB header:transcription Chain: D: PDB Molecule:propionate catabolism operon regulatory protein; PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr 55 d1xfia_ not modelled 61.3 11 Fold:AF1104-like Superfamily:AF1104-like Family:AF1104-like 56 c2zsjB_ not modelled 60.8 17 PDB header:lyase Chain: B: PDB Molecule:threonine synthase; PDBTitle: crystal structure of threonine synthase from aquifex aeolicus vf5 57 d1jw9b_ not modelled 60.7 11 Fold:Activating enzymes of the ubiquitin-like proteins Superfamily:Activating enzymes of the ubiquitin-like proteins Family:Molybdenum cofactor biosynthesis protein MoeB 58 c3ox4D_ not modelled 60.6 14 PDB header:oxidoreductase Chain: D: PDB Molecule:alcohol dehydrogenase 2; PDBTitle: structures of iron-dependent alcohol dehydrogenase 2 from zymomonas2 mobilis zm4 complexed with nad cofactor 59 c3t8yA_ not modelled 60.5 14 PDB header:hydrolase Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate PDBTitle: crystal structure of the response regulator domain of thermotoga2 maritima cheb 60 d1luaa1 not modelled 60.2 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 61 d1v71a1 not modelled 59.3 10 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 62 c2qioA_ not modelled 59.2 11 PDB header:unknown function Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase; PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan 63 c3au9A_ not modelled 59.0 14 PDB header:isomerase/isomerase inhibitor Chain: A: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: crystal structure of the quaternary complex-1 of an isomerase 64 c2hjsA_ not modelled 58.9 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:usg-1 protein homolog; PDBTitle: the structure of a probable aspartate-semialdehyde dehydrogenase from2 pseudomonas aeruginosa 65 d1a04a2 not modelled 57.7 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 66 d1xrsb1 not modelled 57.7 14 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 67 d3ckma1 not modelled 57.6 8 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 68 c3q41B_ not modelled 56.9 10 PDB header:transport protein Chain: B: PDB Molecule:glutamate [nmda] receptor subunit zeta-1; PDBTitle: crystal structure of the glun1 n-terminal domain (ntd) 69 c1luaA_ not modelled 56.6 16 PDB header:oxidoreductase Chain: A: PDB Molecule:methylene tetrahydromethanopterin dehydrogenase; PDBTitle: structure of methylene-tetrahydromethanopterin dehydrogenase from2 methylobacterium extorquens am1 complexed with nadp 70 c3c3wB_ not modelled 55.9 20 PDB header:transcription Chain: B: PDB Molecule:two component transcriptional regulatory protein devr; PDBTitle: crystal structure of the mycobacterium tuberculosis hypoxic response2 regulator dosr 71 d1v7ca_ not modelled 55.7 14 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 72 c3e7dC_ not modelled 55.5 11 PDB header:isomerase Chain: C: PDB Molecule:cobh, precorrin-8x methylmutase; PDBTitle: crystal structure of precorrin-8x methyl mutase cbic/cobh from2 brucella melitensis 73 c3nglA_ not modelled 54.9 20 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of bifunctional 5,10-methylenetetrahydrofolate2 dehydrogenase / cyclohydrolase from thermoplasma acidophilum 74 d1f2va_ not modelled 54.5 14 Fold:Flavodoxin-like Superfamily:Precorrin-8X methylmutase CbiC/CobH Family:Precorrin-8X methylmutase CbiC/CobH 75 d1a9xa4 not modelled 54.4 21 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 76 c1rnlA_ not modelled 54.2 10 PDB header:signal transduction protein Chain: A: PDB Molecule:nitrate/nitrite response regulator protein narl; PDBTitle: the nitrate/nitrite response regulator protein narl from narl 77 d1tjya_ not modelled 54.0 16 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 78 d1w6ua_ not modelled 53.9 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 79 c3a14B_ not modelled 53.5 13 PDB header:oxidoreductase Chain: B: PDB Molecule:1-deoxy-d-xylulose 5-phosphate reductoisomerase; PDBTitle: crystal structure of dxr from thermotoga maritima, in complex with2 nadph 80 d1jbea_ not modelled 53.2 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 81 d1zh2a1 not modelled 53.0 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 82 c3uw3A_ not modelled 52.3 13 PDB header:oxidoreductase Chain: A: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: crystal structure of an aspartate-semialdehyde dehydrogenase from2 burkholderia thailandensis 83 c3s99A_ not modelled 51.3 12 PDB header:lipid binding protein Chain: A: PDB Molecule:basic membrane lipoprotein; PDBTitle: crystal structure of a basic membrane lipoprotein from brucella2 melitensis, iodide soak 84 d1txga2 not modelled 51.3 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 85 c3a0rB_ not modelled 51.1 13 PDB header:transferase Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360) 86 d1fmfa_ not modelled 51.0 12 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 87 c3iauA_ not modelled 50.2 11 PDB header:lyase Chain: A: PDB Molecule:threonine deaminase; PDBTitle: the structure of the processed form of threonine deaminase isoform 22 from solanum lycopersicum 88 d1i3ca_ not modelled 50.0 10 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 89 d2g8la1 not modelled 49.7 13 Fold:AF1104-like Superfamily:AF1104-like Family:AF1104-like 90 d1zgza1 not modelled 49.6 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 91 c3cz5B_ not modelled 49.5 14 PDB header:transcription regulator Chain: B: PDB Molecule:two-component response regulator, luxr family; PDBTitle: crystal structure of two-component response regulator, luxr family,2 from aurantimonas sp. si85-9a1 92 d1q0qa2 not modelled 49.5 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 93 d1krwa_ not modelled 49.1 10 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 94 d2ffja1 not modelled 48.7 22 Fold:AF1104-like Superfamily:AF1104-like Family:AF1104-like 95 d1jq5a_ not modelled 48.2 8 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 96 c1vknC_ not modelled 48.1 14 PDB header:oxidoreductase Chain: C: PDB Molecule:n-acetyl-gamma-glutamyl-phosphate reductase; PDBTitle: crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase2 (tm1782) from thermotoga maritima at 1.80 a resolution 97 c3bfjK_ not modelled 47.5 20 PDB header:oxidoreductase Chain: K: PDB Molecule:1,3-propanediol oxidoreductase; PDBTitle: crystal structure analysis of 1,3-propanediol oxidoreductase 98 c1bmtB_ not modelled 46.7 8 PDB header:methyltransferase Chain: B: PDB Molecule:methionine synthase; PDBTitle: how a protein binds b12: a 3.o angstrom x-ray structure of2 the b12-binding domains of methionine synthase 99 c2afvB_ not modelled 46.1 16 PDB header:isomerase Chain: B: PDB Molecule:cobalamin biosynthesis precorrin isomerase; PDBTitle: the crystal structure of putative precorrin isomerase cbic2 in cobalamin biosynthesis 100 c2rkbE_ not modelled 45.9 19 PDB header:lyase Chain: E: PDB Molecule:serine dehydratase-like; PDBTitle: serine dehydratase like-1 from human cancer cells 101 c1zfnA_ not modelled 45.5 9 PDB header:transferase Chain: A: PDB Molecule:adenylyltransferase thif; PDBTitle: structural analysis of escherichia coli thif 102 c2d1fA_ not modelled 45.0 9 PDB header:lyase Chain: A: PDB Molecule:threonine synthase; PDBTitle: structure of mycobacterium tuberculosis threonine synthase 103 d1ve5a1 not modelled 44.8 12 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 104 d3dc7a1 not modelled 44.3 13 Fold:Flavodoxin-like Superfamily:SGNH hydrolase Family:BT2961-like 105 d1s8na_ not modelled 44.0 14 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 106 c2gn0A_ not modelled 44.0 12 PDB header:lyase Chain: A: PDB Molecule:threonine dehydratase catabolic; PDBTitle: crystal structure of dimeric biodegradative threonine deaminase (tdcb)2 from salmonella typhimurium at 1.7 a resolution (triclinic form with3 one complete subunit built in alternate conformation) 107 c3sc6F_ not modelled 43.9 10 PDB header:oxidoreductase Chain: F: PDB Molecule:dtdp-4-dehydrorhamnose reductase; PDBTitle: 2.65 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 reductase (rfbd) from bacillus anthracis str. ames in complex with3 nadp 108 d1xsea_ not modelled 43.5 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 109 c3bolB_ not modelled 43.5 12 PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ 110 d1pqua1 not modelled 43.1 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 111 c3l6cA_ not modelled 43.0 7 PDB header:isomerase Chain: A: PDB Molecule:serine racemase; PDBTitle: x-ray crystal structure of rat serine racemase in complex with2 malonate a potent inhibitor 112 c2q49B_ not modelled 42.8 14 PDB header:oxidoreductase Chain: B: PDB Molecule:probable n-acetyl-gamma-glutamyl-phosphate reductase; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at2g19940 113 c3t0nA_ not modelled 42.2 12 PDB header:signaling protein Chain: A: PDB Molecule:twin-arginine translocation pathway signal; PDBTitle: crystal structure of twin-arginine translocation pathway signal from2 rhodopseudomonas palustris bisb5 114 d1vjga_ not modelled 42.1 14 Fold:Flavodoxin-like Superfamily:SGNH hydrolase Family:Hypothetical protein alr1529 115 c2qv0A_ not modelled 41.5 10 PDB header:transcription Chain: A: PDB Molecule:protein mrke; PDBTitle: crystal structure of the response regulatory domain of2 protein mrke from klebsiella pneumoniae 116 c2qz9B_ not modelled 41.5 11 PDB header:oxidoreductase Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase; PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase2 ii from vibrio cholerae 117 d1xcfa_ not modelled 41.4 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 118 d1kq3a_ not modelled 41.1 14 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 119 d1a2oa1 not modelled 41.0 12 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 120 c2yyaB_ not modelled 40.1 18 PDB header:ligase Chain: B: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of gar synthetase from aquifex aeolicus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0