Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	W	F	I	D	R	R	L	N	G	K	N	K	S	M	V	N	R	Q	R	F	L	R	R	Y	K	A	Q	I	K	Q	S	I	S	E	A	I	N	K	R	S	V	T	D	V	D	S	G	E	S	V	S	I	P	T	E	D	I	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?			?	?	?	?	?																								?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	P	M	F	H	Q	G	R	G	G	L	R	H	R	V	H	P	G	N	D	H	F	V	Q	N	D	R	I	E	R	P	Q	G	G	G	G	G	S	G	S	G	Q	G	Q	A	S	Q	D	G	E	G	Q	D	E	F	V	F	Q	I	S
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		K	D	E	Y	L	D	L	L	F	E	D	L	A	L	P	N	L	K	Q	N	Q	Q	R	Q	L	T	E	Y	K	T	H	R	A	G	Y	T	A	N	G	V	P	A	N	I	S	V	V	R	S	L	Q	N	S	L	A	R	R	T	A	M
Secondary structure
SS confidence
Disorder																		?		?	?	?	?	?	?	?	?	?	?														?	?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	A	G	K	R	R	E	L	H	A	L	E	E	N	L	A	I	I	S	N	S	E	P	A	Q	L	L	E	E	E	R	L	R	K	E	I	A	E	L	R	A	K	I	E	R	V	P	F	I	D	T	F	D	L	R	Y	K	N	Y	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?													?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?				?																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		K	R	P	D	P	S	S	Q	A	V	M	F	C	L	M	D	V	S	G	S	M	D	Q	S	T	K	D	M	A	K	R	F	Y	I	L	L	Y	L	F	L	S	R	T	Y	K	N	V	E	V	V	Y	I	R	H	H	T	Q	A	K	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	D	E	H	E	F	F	Y	S	Q	E	T	G	G	T	I	V	S	S	A	L	K	L	M	D	E	V	V	K	E	R	Y	N	P	A	Q	W	N	I	Y	A	A	Q	A	S	D	G	D	N	W	A	D	D	S	P	L	C	H	E	I
Secondary structure
SS confidence
Disorder										?	?		?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	A	K	K	L	L	P	V	V	R	Y	Y	S	Y	I	E	I	T	R	R	A	H	Q	T	L	W	R	E	Y	E	H	L	Q	S	T	F	D	N	F	A	M	Q	H	I	R	D	Q	D	D	I	Y	P	V	F	R	E	L	F	H	K
Secondary structure
SS confidence
Disorder																					?	?	?	?	?								?	?													?	?	?											?	?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		Q	N	A	T	A	K	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1rs0 chain A Region: 251 - 426 Aligned: 172 Modelled: 176 Confidence: 99.6% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: crystal structure analysis of the bb segment of factor b2 complexed with di-isopropyl-phosphate (dip) Phyre2 PDB 2ok5 chain A Region: 245 - 421 Aligned: 172 Modelled: 177 Confidence: 99.5% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: human complement factor b Phyre2 PDB 2ok5 chain A domain 1 Region: 241 - 423 Aligned: 180 Modelled: 179 Confidence: 99.5% Identity: 15% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 2i6s chain A Region: 251 - 419 Aligned: 158 Modelled: 169 Confidence: 99.4% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:complement c2a fragment; PDBTitle: complement component c2a Phyre2 PDB 2x5n chain A Region: 251 - 411 Aligned: 155 Modelled: 161 Confidence: 99.4% Identity: 11% PDB header:nuclear protein Chain: A: PDB Molecule:26s proteasome regulatory subunit rpn10; PDBTitle: crystal structure of the sprpn10 vwa domain Phyre2 PDB 2iue chain A Region: 251 - 419 Aligned: 167 Modelled: 169 Confidence: 99.4% Identity: 13% PDB header:membrane protein Chain: A: PDB Molecule:pactolus i-domain; PDBTitle: pactolus i-domain: functional switching of the rossmann2 fold Phyre2 PDB 1jey chain B domain 2 Region: 247 - 383 Aligned: 137 Modelled: 137 Confidence: 99.3% Identity: 13% Fold: vWA-like Superfamily: vWA-like Family: Ku80 subunit N-terminal domain Phyre2 PDB 1ijb chain A Region: 251 - 420 Aligned: 166 Modelled: 170 Confidence: 99.2% Identity: 11% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 3ibs chain A Region: 251 - 424 Aligned: 160 Modelled: 174 Confidence: 99.2% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein batb; PDBTitle: crystal structure of conserved hypothetical protein batb from2 bacteroides thetaiotaomicron Phyre2 PDB 2nvo chain A Region: 244 - 383 Aligned: 129 Modelled: 137 Confidence: 99.1% Identity: 16% PDB header:rna binding protein Chain: A: PDB Molecule:ro sixty-related protein, rsr; PDBTitle: crystal structure of deinococcus radiodurans ro (rsr) protein Phyre2 PDB 1jey chain A domain 2 Region: 248 - 375 Aligned: 127 Modelled: 128 Confidence: 99.1% Identity: 12% Fold: vWA-like Superfamily: vWA-like Family: Ku70 subunit N-terminal domain Phyre2 PDB 1yvr chain A domain 2 Region: 244 - 383 Aligned: 128 Modelled: 140 Confidence: 99.1% Identity: 14% Fold: vWA-like Superfamily: vWA-like Family: RoRNP C-terminal domain-like Phyre2 PDB 1u0o chain C domain 1 Region: 251 - 420 Aligned: 166 Modelled: 170 Confidence: 99.1% Identity: 11% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 2x31 chain F Region: 244 - 357 Aligned: 109 Modelled: 114 Confidence: 99.1% Identity: 21% PDB header:ligase Chain: F: PDB Molecule:magnesium-chelatase 60 kda subunit; PDBTitle: modelling of the complex between subunits bchi and bchd of magnesium2 chelatase based on single-particle cryo-em reconstruction at 7.5 ang Phyre2 PDB 1shu chain X Region: 251 - 420 Aligned: 160 Modelled: 165 Confidence: 99.0% Identity: 14% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 1q0p chain A Region: 251 - 401 Aligned: 150 Modelled: 151 Confidence: 99.0% Identity: 16% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 2xgg chain B Region: 251 - 375 Aligned: 123 Modelled: 125 Confidence: 99.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:microneme protein 2; PDBTitle: structure of toxoplasma gondii micronemal protein 2 a_i2 domain Phyre2 PDB 3n2n chain C Region: 251 - 424 Aligned: 161 Modelled: 174 Confidence: 98.9% Identity: 14% PDB header:toxin receptor Chain: C: PDB Molecule:anthrax toxin receptor 1; PDBTitle: the crystal structure of tumor endothelial marker 8 (tem8)2 extracellular domain Phyre2 PDB 1jey chain B Region: 248 - 373 Aligned: 126 Modelled: 126 Confidence: 98.9% Identity: 13% PDB header:dna binding protein/dna Chain: B: PDB Molecule:ku80; PDBTitle: crystal structure of the ku heterodimer bound to dna Phyre2 PDB 2b2x chain B Region: 251 - 420 Aligned: 163 Modelled: 170 Confidence: 98.9% Identity: 12% PDB header:immune system Chain: B: PDB Molecule:integrin alpha-1; PDBTitle: vla1 rdeltah i-domain complexed with a quadruple mutant of the aqc22 fab Phyre2 PDB 1yvr chain A Region: 160 - 383 Aligned: 214 Modelled: 214 Confidence: 98.2% Identity: 15% PDB header:rna binding protein Chain: A: PDB Molecule:60-kda ss-a/ro ribonucleoprotein; PDBTitle: ro autoantigen Phyre2 1 c1rs0A_ 2 c2ok5A_ 3 d2ok5a1 4 c2i6sA_ 5 c2x5nA_ 6 c2iueA_ 7 d1jeyb2 8 d1ijba_ 9 c3ibsA_ 10 c2nvoA_ 11 d1jeya2 12 d1yvra2 13 d1u0oc1 14 c2x31F_ 15 d1shux_ 16 d1q0pa_ 17 c2xggB_ 18 c3n2nC_ 19 c1jeyB_ 20 c2b2xB_ 21 22 23 24 25 26 27 28 29 30 31 32 c1yvrA_ 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1rs0A_ 99.6 15 PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: crystal structure analysis of the bb segment of factor b2 complexed with di-isopropyl-phosphate (dip) 2 c2ok5A_ 99.5 17 PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: human complement factor b 3 d2ok5a1 99.5 15 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 4 c2i6sA_ 99.4 18 PDB header:hydrolase Chain: A: PDB Molecule:complement c2a fragment; PDBTitle: complement component c2a 5 c2x5nA_ 99.4 11 PDB header:nuclear protein Chain: A: PDB Molecule:26s proteasome regulatory subunit rpn10; PDBTitle: crystal structure of the sprpn10 vwa domain 6 c2iueA_ 99.4 13 PDB header:membrane protein Chain: A: PDB Molecule:pactolus i-domain; PDBTitle: pactolus i-domain: functional switching of the rossmann2 fold 7 d1jeyb2 99.3 13 Fold:vWA-like Superfamily:vWA-like Family:Ku80 subunit N-terminal domain 8 d1ijba_ 99.2 11 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 9 c3ibsA_ 99.2 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein batb; PDBTitle: crystal structure of conserved hypothetical protein batb from2 bacteroides thetaiotaomicron 10 c2nvoA_ 99.1 16 PDB header:rna binding protein Chain: A: PDB Molecule:ro sixty-related protein, rsr; PDBTitle: crystal structure of deinococcus radiodurans ro (rsr) protein 11 d1jeya2 99.1 12 Fold:vWA-like Superfamily:vWA-like Family:Ku70 subunit N-terminal domain 12 d1yvra2 99.1 14 Fold:vWA-like Superfamily:vWA-like Family:RoRNP C-terminal domain-like 13 d1u0oc1 99.1 11 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 14 c2x31F_ 99.1 21 PDB header:ligase Chain: F: PDB Molecule:magnesium-chelatase 60 kda subunit; PDBTitle: modelling of the complex between subunits bchi and bchd of magnesium2 chelatase based on single-particle cryo-em reconstruction at 7.5 ang 15 d1shux_ 99.0 14 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 16 d1q0pa_ 99.0 16 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 17 c2xggB_ 99.0 16 PDB header:hydrolase Chain: B: PDB Molecule:microneme protein 2; PDBTitle: structure of toxoplasma gondii micronemal protein 2 a_i2 domain 18 c3n2nC_ 98.9 14 PDB header:toxin receptor Chain: C: PDB Molecule:anthrax toxin receptor 1; PDBTitle: the crystal structure of tumor endothelial marker 8 (tem8)2 extracellular domain 19 c1jeyB_ 98.9 13 PDB header:dna binding protein/dna Chain: B: PDB Molecule:ku80; PDBTitle: crystal structure of the ku heterodimer bound to dna 20 c2b2xB_ 98.9 12 PDB header:immune system Chain: B: PDB Molecule:integrin alpha-1; PDBTitle: vla1 rdeltah i-domain complexed with a quadruple mutant of the aqc22 fab 21 d1v7pc_ not modelled 98.9 11 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 22 d1atza_ not modelled 98.8 13 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 23 d1n3ya_ not modelled 98.8 15 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 24 c3gxbB_ not modelled 98.8 10 PDB header:cell adhesion Chain: B: PDB Molecule:von willebrand factor; PDBTitle: crystal structure of vwf a2 domain 25 d1pt6a_ not modelled 98.8 11 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 26 d1mjna_ not modelled 98.8 15 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 27 d1ck4a_ not modelled 98.7 11 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 28 d1mf7a_ not modelled 98.7 12 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 29 d1pd0a3 not modelled 98.6 13 Fold:vWA-like Superfamily:vWA-like Family:Trunk domain of Sec23/24 30 c3ragA_ not modelled 98.4 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein aaci_0196 from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446 31 d1tyeb2 not modelled 98.3 16 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 32 c1yvrA_ 98.2 15 PDB header:rna binding protein Chain: A: PDB Molecule:60-kda ss-a/ro ribonucleoprotein; PDBTitle: ro autoantigen 33 c3v4pB_ not modelled 98.0 15 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-7; PDBTitle: crystal structure of a4b7 headpiece complexed with fab act-1 34 c3fcuB_ not modelled 98.0 16 PDB header:cell adhesion/blood clotting Chain: B: PDB Molecule:integrin beta-3; PDBTitle: structure of headpiece of integrin aiibb3 in open conformation 35 c1jeqA_ not modelled 97.5 13 PDB header:dna binding protein Chain: A: PDB Molecule:ku70; PDBTitle: crystal structure of the ku heterodimer 36 c1u8cB_ not modelled 97.2 15 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: a novel adaptation of the integrin psi domain revealed from its2 crystal structure 37 c3k6sB_ not modelled 96.1 14 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-2; PDBTitle: structure of integrin alphaxbeta2 ectodomain 38 c1pd0A_ not modelled 96.0 13 PDB header:transport protein Chain: A: PDB Molecule:protein transport protein sec24; PDBTitle: crystal structure of the copii coat subunit, sec24,2 complexed with a peptide from the snare protein sed53 (yeast syntaxin-5) 39 c1m2vB_ not modelled 95.2 14 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24; PDBTitle: crystal structure of the yeast sec23/24 heterodimer 40 c3eg9B_ not modelled 89.8 14 PDB header:protein transport Chain: B: PDB Molecule:sec24 related gene family, member d; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23/24 bound to the transport signal sequence of membrin 41 c3egxB_ not modelled 89.1 13 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24a; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23a/24a complexed with the snare protein sec22b and3 bound to the transport signal sequence of the snare protein4 bet1 42 c3eg9A_ not modelled 84.2 15 PDB header:protein transport Chain: A: PDB Molecule:protein transport protein sec23a; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23/24 bound to the transport signal sequence of membrin 43 d2qtva3 not modelled 82.5 15 Fold:vWA-like Superfamily:vWA-like Family:Trunk domain of Sec23/24 44 c3eh2B_ not modelled 78.2 13 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24c; PDBTitle: crystal structure of the human copii-coat protein sec24c 45 c1m2oA_ not modelled 54.8 17 PDB header:protein transport/signaling protein Chain: A: PDB Molecule:protein transport protein sec23; PDBTitle: crystal structure of the sec23-sar1 complex 46 d1h7na_ not modelled 37.0 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 47 c3atyA_ not modelled 33.5 11 PDB header:oxidoreductase Chain: A: PDB Molecule:prostaglandin f2a synthase; PDBTitle: crystal structure of tcoye 48 c2ftpA_ not modelled 31.8 16 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 49 d1vjia_ not modelled 26.4 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 50 d2c1ha1 not modelled 25.4 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 51 d1ja1a2 not modelled 25.2 13 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 52 d1boba_ not modelled 23.0 8 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT 53 c3sggA_ not modelled 21.8 29 PDB header:hydrolase Chain: A: PDB Molecule:hypothetical hydrolase; PDBTitle: crystal structure of a hypothetical hydrolase (bt_2193) from2 bacteroides thetaiotaomicron vpi-5482 at 1.25 a resolution 54 d1icpa_ not modelled 20.7 26 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 55 d1gwja_ not modelled 20.4 23 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 56 c3czpA_ not modelled 20.0 19 PDB header:transferase Chain: A: PDB Molecule:putative polyphosphate kinase 2; PDBTitle: crystal structure of putative polyphosphate kinase 2 from pseudomonas2 aeruginosa pa01 57 c1ydnA_ not modelled 18.3 15 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 58 d1irud_ not modelled 17.5 21 Fold:Ntn hydrolase-like Superfamily:N-terminal nucleophile aminohydrolases (Ntn hydrolases) Family:Proteasome subunits 59 c1ydoC_ not modelled 15.4 16 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 60 c3komB_ not modelled 14.5 13 PDB header:transferase Chain: B: PDB Molecule:transketolase; PDBTitle: crystal structure of apo transketolase from francisella tularensis 61 d1l6sa_ not modelled 13.4 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 62 c3l5aA_ not modelled 13.3 20 PDB header:oxidoreductase Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus 63 d1uiza_ not modelled 12.0 11 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MIF-related 64 d1w5fa2 not modelled 11.9 11 Fold:Bacillus chorismate mutase-like Superfamily:Tubulin C-terminal domain-like Family:Tubulin, C-terminal domain 65 c3mwbA_ not modelled 11.7 18 PDB header:lyase Chain: A: PDB Molecule:prephenate dehydratase; PDBTitle: the crystal structure of prephenate dehydratase in complex with l-phe2 from arthrobacter aurescens to 2.0a 66 c3fwtA_ not modelled 11.5 11 PDB header:cytokine Chain: A: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: crystal structure of leishmania major mif2 67 d1gzga_ not modelled 10.8 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 68 c2p0wB_ not modelled 10.8 13 PDB header:transferase Chain: B: PDB Molecule:histone acetyltransferase type b catalytic subunit; PDBTitle: human histone acetyltransferase 1 (hat1) 69 d1vh4a_ not modelled 10.6 25 Fold:Single-stranded right-handed beta-helix Superfamily:Stabilizer of iron transporter SufD Family:Stabilizer of iron transporter SufD 70 d2vapa2 not modelled 9.9 4 Fold:Bacillus chorismate mutase-like Superfamily:Tubulin C-terminal domain-like Family:Tubulin, C-terminal domain 71 c2l42A_ not modelled 9.4 19 PDB header:protein binding Chain: A: PDB Molecule:dna-binding protein rap1; PDBTitle: the solution structure of rap1 brct domain from saccharomyces2 cerevisiae 72 c3vcbB_ not modelled 9.2 20 PDB header:viral protein Chain: B: PDB Molecule:rna-directed rna polymerase; PDBTitle: c425s mutant of the c-terminal cytoplasmic domain of non-structural2 protein 4 from mouse hepatitis virus a59 73 d2fcja1 not modelled 9.1 24 Fold:Toprim domain Superfamily:Toprim domain Family:Toprim domain 74 d1q45a_ not modelled 8.8 25 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 75 d1bmlc1 not modelled 8.6 22 Fold:beta-Grasp (ubiquitin-like) Superfamily:Staphylokinase/streptokinase Family:Staphylokinase/streptokinase 76 d1g8fa3 not modelled 8.4 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ATP sulfurylase C-terminal domain 77 c3luyA_ not modelled 8.2 7 PDB header:isomerase Chain: A: PDB Molecule:probable chorismate mutase; PDBTitle: putative chorismate mutase from bifidobacterium adolescentis 78 d1xhoa_ not modelled 8.1 45 Fold:Bacillus chorismate mutase-like Superfamily:YjgF-like Family:Chorismate mutase 79 c2xczA_ not modelled 8.0 12 PDB header:immune system Chain: A: PDB Molecule:possible atls1-like light-inducible protein; PDBTitle: crystal structure of macrophage migration inhibitory factor2 homologue from prochlorococcus marinus 80 c1xhoB_ not modelled 7.7 42 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:chorismate mutase; PDBTitle: chorismate mutase from clostridium thermocellum cth-682 81 c3lukB_ not modelled 7.4 9 PDB header:rna binding protein Chain: B: PDB Molecule:protein argonaute-2; PDBTitle: crystal structure of mid domain from hago2 82 d1rhya2 not modelled 7.4 20 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Imidazole glycerol phosphate dehydratase 83 d1xg8a_ not modelled 7.4 35 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:YuzD-like 84 c3gzfD_ not modelled 7.2 28 PDB header:viral protein Chain: D: PDB Molecule:replicase polyprotein 1ab; PDBTitle: structure of the c-terminal domain of nsp4 from feline coronavirus 85 c3dmaA_ not modelled 7.1 31 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:exopolyphosphatase-related protein; PDBTitle: crystal structure of an exopolyphosphatase-related protein2 from bacteroides fragilis. northeast structural genomics3 target bfr192 86 c2k19A_ not modelled 7.1 15 PDB header:antimicrobial protein Chain: A: PDB Molecule:putative piscicolin 126 immunity protein; PDBTitle: nmr solution structure of pisi 87 c2qtxL_ not modelled 7.0 86 PDB header:rna binding protein Chain: L: PDB Molecule:uncharacterized protein mj1435; PDBTitle: crystal structure of an hfq-like protein from methanococcus2 jannaschii 88 c3b64A_ not modelled 7.0 9 PDB header:cytokine Chain: A: PDB Molecule:macrophage migration inhibitory factor-like PDBTitle: macrophage migration inhibitory factor (mif) from2 /leishmania major 89 d2qmwa2 not modelled 7.0 12 Fold:Ferredoxin-like Superfamily:ACT-like Family:Phenylalanine metabolism regulatory domain 90 d1nxha_ not modelled 6.8 24 Fold:Hypothetical protein MTH393 Superfamily:Hypothetical protein MTH393 Family:Hypothetical protein MTH393 91 d2cp8a1 not modelled 6.6 44 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:UBA domain 92 c3cs5B_ not modelled 6.5 28 PDB header:photosynthesis Chain: B: PDB Molecule:phycobilisome degradation protein nbla; PDBTitle: nbla protein from synechococcus elongatus pcc 7942 93 d2dfaa1 not modelled 6.5 11 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:LamB/YcsF-like 94 c2h90A_ not modelled 6.5 26 PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin 95 c3eukC_ not modelled 6.3 18 PDB header:cell cycle Chain: C: PDB Molecule:chromosome partition protein mukb, linker; PDBTitle: crystal structure of muke-mukf(residues 292-443)-mukb(head2 domain)-atpgammas complex, asymmetric dimer 96 d2ae8a2 not modelled 6.3 27 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Imidazole glycerol phosphate dehydratase 97 d1vyra_ not modelled 6.3 18 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 98 d1pv8a_ not modelled 6.2 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 99 d1l4zb_ not modelled 6.2 21 Fold:beta-Grasp (ubiquitin-like) Superfamily:Staphylokinase/streptokinase Family:Staphylokinase/streptokinase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0