Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76403
DateThu Jan 5 12:22:42 GMT 2012
Unique Job ID094c41be0ddcb11b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2bdqA_
Top template information
PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.
Confidence and coverage
Confidence: 98.1% Coverage: 34%
156 residues ( 34% of your sequence) have been modelled with 98.1% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
265 residues ( 58%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLQLGINEAHALGK
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Disorder  ????























































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   .........70.........80.........90.........100.........110.........120
Sequence  KFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIMLVREHFPEMPIHLSVQAN
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   .........130.........140.........150.........160.........170.........180
Sequence  AVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDMEIEIFVHGALCMAYSGRCLLS
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   .........190.........200.........210.........220.........230.........240
Sequence  GYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKYEPIPVQNVEPTLGIGAPTDKVF
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Disorder 





??
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???????







?????




?


?
?


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   .........250.........260.........270.........280.........290.........300
Sequence  MIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVERLTKMGVHSLKIEGRTKSFYYCAR
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Disorder 




????


















































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   .........310.........320.........330.........340.........350.........360
Sequence  TAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGYTEGFLRRHTHDDYQNYEYGYSVSDRQ
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??
???????????


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   .........370.........380.........390.........400.........410.........420
Sequence  QFVGEFTGERKGDLAAVAVKNKFSVGDSLELMTPQGNINFTLEHMENAKGEAMPIAPGDG
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?



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   .........430.........440.........450...
Sequence  YTVWLPVPQDLELNYALLMRNFSGETTRNPHGK
Secondary structure 



















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Disorder 










?






?


??????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2bdq chain A

3D model

Region: 6 - 167
Aligned: 156
Modelled: 157
Confidence: 98.1%
Identity: 18%
PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.

Phyre2

PDB 3qja chain A

3D model

Region: 12 - 140
Aligned: 108
Modelled: 116
Confidence: 98.0%
Identity: 15%
PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form

Phyre2

PDB 1xi3 chain A

3D model

Region: 13 - 313
Aligned: 174
Modelled: 186
Confidence: 97.9%
Identity: 19%
Fold: TIM beta/alpha-barrel
Superfamily: Thiamin phosphate synthase
Family: Thiamin phosphate synthase

Phyre2

PDB 1a53 chain A

3D model

Region: 12 - 140
Aligned: 108
Modelled: 119
Confidence: 97.9%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 1twd chain A

3D model

Region: 6 - 315
Aligned: 201
Modelled: 206
Confidence: 97.9%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: CutC-like
Family: CutC-like

Phyre2

PDB 2c3z chain A

3D model

Region: 12 - 140
Aligned: 108
Modelled: 120
Confidence: 97.8%
Identity: 14%
PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus

Phyre2

PDB 1vli chain A domain 2

3D model

Region: 2 - 166
Aligned: 151
Modelled: 158
Confidence: 97.8%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: NeuB-like

Phyre2

PDB 1vli chain A

3D model

Region: 2 - 166
Aligned: 151
Modelled: 158
Confidence: 97.7%
Identity: 16%
PDB header:biosynthetic protein
Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse;
PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution

Phyre2

PDB 2ze3 chain A

3D model

Region: 2 - 170
Aligned: 167
Modelled: 168
Confidence: 97.6%
Identity: 11%
PDB header:isomerase
Chain: A: PDB Molecule:dfa0005;
PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus

Phyre2

PDB 2zdr chain A domain 2

3D model

Region: 2 - 161
Aligned: 150
Modelled: 152
Confidence: 97.6%
Identity: 23%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: NeuB-like

Phyre2

PDB 1xuz chain A

3D model

Region: 2 - 166
Aligned: 151
Modelled: 151
Confidence: 97.6%
Identity: 24%
PDB header:biosynthetic protein
Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac;
PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol

Phyre2

PDB 3igs chain B

3D model

Region: 11 - 140
Aligned: 108
Modelled: 128
Confidence: 97.5%
Identity: 13%
PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase

Phyre2

PDB 3iwp chain K

3D model

Region: 6 - 167
Aligned: 155
Modelled: 161
Confidence: 97.5%
Identity: 17%
PDB header:metal binding protein
Chain: K: PDB Molecule:copper homeostasis protein cutc homolog;
PDBTitle: crystal structure of human copper homeostasis protein cutc

Phyre2

PDB 1pii chain A

3D model

Region: 12 - 165
Aligned: 130
Modelled: 154
Confidence: 97.5%
Identity: 20%
PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution

Phyre2

PDB 3ble chain A

3D model

Region: 1 - 141
Aligned: 138
Modelled: 141
Confidence: 97.5%
Identity: 12%
PDB header:transferase
Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans;
PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate

Phyre2

PDB 2tps chain A

3D model

Region: 13 - 316
Aligned: 181
Modelled: 187
Confidence: 97.4%
Identity: 21%
Fold: TIM beta/alpha-barrel
Superfamily: Thiamin phosphate synthase
Family: Thiamin phosphate synthase

Phyre2

PDB 3kts chain A

3D model

Region: 6 - 182
Aligned: 159
Modelled: 170
Confidence: 97.4%
Identity: 19%
PDB header:transcriptional regulator
Chain: A: PDB Molecule:glycerol uptake operon antiterminator regulatory protein;
PDBTitle: crystal structure of glycerol uptake operon antiterminator regulatory2 protein from listeria monocytogenes str. 4b f2365

Phyre2

PDB 1yad chain D

3D model

Region: 9 - 312
Aligned: 173
Modelled: 189
Confidence: 97.4%
Identity: 15%
PDB header:transcription
Chain: D: PDB Molecule:regulatory protein teni;
PDBTitle: structure of teni from bacillus subtilis

Phyre2

PDB 3fa4 chain D

3D model

Region: 1 - 161
Aligned: 161
Modelled: 161
Confidence: 97.4%
Identity: 12%
PDB header:lyase
Chain: D: PDB Molecule:2,3-dimethylmalate lyase;
PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form

Phyre2

PDB 3ivu chain B

3D model

Region: 1 - 141
Aligned: 136
Modelled: 141
Confidence: 97.3%
Identity: 18%
PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og

Phyre2

PDB 3inp chain A

3D model

Region: 74 - 312
Aligned: 191
Modelled: 191
Confidence: 96.0%
Identity: 14%
PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.

Phyre2
1

c2bdqA_
2

c3qjaA_
3

d1xi3a_
4

d1a53a_
5

d1twda_
6

c2c3zA_
7

d1vlia2
8

c1vliA_
9

c2ze3A_
10

d2zdra2
11

c1xuzA_
12

c3igsB_
13

c3iwpK_
14

c1piiA_
15

c3bleA_
16

d2tpsa_
17

c3ktsA_
18

c1yadD_
19

c3fa4D_
20

c3ivuB_
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c3inpA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2bdqA_



98.1 18 PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.
2c3qjaA_



98.0 15 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
3d1xi3a_



97.9 19 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
4d1a53a_



97.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
5d1twda_



97.9 18 Fold:TIM beta/alpha-barrel
Superfamily:CutC-like
Family:CutC-like
6c2c3zA_



97.8 14 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
7d1vlia2



97.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
8c1vliA_



97.7 16 PDB header:biosynthetic protein
Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse;
PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution
9c2ze3A_



97.6 11 PDB header:isomerase
Chain: A: PDB Molecule:dfa0005;
PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus
10d2zdra2



97.6 23 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
11c1xuzA_



97.6 24 PDB header:biosynthetic protein
Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac;
PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol
12c3igsB_



97.5 13 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
13c3iwpK_



97.5 17 PDB header:metal binding protein
Chain: K: PDB Molecule:copper homeostasis protein cutc homolog;
PDBTitle: crystal structure of human copper homeostasis protein cutc
14c1piiA_



97.5 20 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
15c3bleA_



97.5 12 PDB header:transferase
Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans;
PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate
16d2tpsa_



97.4 21 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
17c3ktsA_



97.4 19 PDB header:transcriptional regulator
Chain: A: PDB Molecule:glycerol uptake operon antiterminator regulatory protein;
PDBTitle: crystal structure of glycerol uptake operon antiterminator regulatory2 protein from listeria monocytogenes str. 4b f2365
18c1yadD_



97.4 15 PDB header:transcription
Chain: D: PDB Molecule:regulatory protein teni;
PDBTitle: structure of teni from bacillus subtilis
19c3fa4D_



97.4 12 PDB header:lyase
Chain: D: PDB Molecule:2,3-dimethylmalate lyase;
PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form
20c3ivuB_



97.3 18 PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og
21d1j5ta_



not modelled 97.3 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
22c2ekcA_



not modelled 97.3 18 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
23d1vc4a_



not modelled 97.2 25 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
24d1geqa_



not modelled 97.2 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
25c3q58A_



not modelled 97.2 13 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
26d1piia2



not modelled 97.2 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
27c3gr7A_



not modelled 97.2 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
28d1wa3a1



not modelled 97.1 19 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
29d1i4na_



not modelled 97.1 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
30c3lyeA_



not modelled 97.1 13 PDB header:hydrolase
Chain: A: PDB Molecule:oxaloacetate acetyl hydrolase;
PDBTitle: crystal structure of oxaloacetate acetylhydrolase
31c2cw6B_



not modelled 97.1 20 PDB header:lyase
Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial;
PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
32d1muma_



not modelled 97.1 15 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like
33d1ub3a_



not modelled 97.1 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
34c3ih1A_



not modelled 97.0 16 PDB header:lyase
Chain: A: PDB Molecule:methylisocitrate lyase;
PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis
35c2ftpA_



not modelled 97.0 18 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa
36d1e0ta2



not modelled 97.0 19 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Pyruvate kinase
37d1h5ya_



not modelled 97.0 24 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
38d1ojxa_



not modelled 97.0 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
39c1e0tD_



not modelled 97.0 19 PDB header:phosphotransferase
Chain: D: PDB Molecule:pyruvate kinase;
PDBTitle: r292d mutant of e. coli pyruvate kinase
40c3eooL_



not modelled 96.9 16 PDB header:lyase
Chain: L: PDB Molecule:methylisocitrate lyase;
PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei
41c1zlpA_



not modelled 96.9 12 PDB header:lyase
Chain: A: PDB Molecule:petal death protein;
PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct
42d1yxya1



not modelled 96.9 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
43d1qo2a_



not modelled 96.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
44d1thfd_



not modelled 96.9 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
45c3oa3A_



not modelled 96.9 11 PDB header:lyase
Chain: A: PDB Molecule:aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis
46c3q94B_



not modelled 96.9 17 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii;
PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'
47d1o0ya_



not modelled 96.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
48d1vzwa1



not modelled 96.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
49d1jvna1



not modelled 96.8 20 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
50d1mzha_



not modelled 96.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
51c2iswB_



not modelled 96.7 17 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase;
PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate
52d1nvma2



not modelled 96.7 19 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
53c3sz8D_



not modelled 96.7 10 PDB header:transferase
Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2;
PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei
54d1geha1



not modelled 96.6 19 Fold:TIM beta/alpha-barrel
Superfamily:RuBisCo, C-terminal domain
Family:RuBisCo, large subunit, C-terminal domain
55c3pm6B_



not modelled 96.6 15 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase;
PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr
56d1mxsa_



not modelled 96.6 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
57c1ydnA_



not modelled 96.5 17 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35.
58c3gndC_



not modelled 96.5 15 PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
59c3t7vA_



not modelled 96.5 18 PDB header:transferase
Chain: A: PDB Molecule:methylornithine synthase pylb;
PDBTitle: crystal structure of methylornithine synthase (pylb)
60c1nvmG_



not modelled 96.5 18 PDB header:lyase/oxidoreductase
Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase;
PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate
61d1gvfa_



not modelled 96.5 18 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
62d1y0ea_



not modelled 96.5 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
63c3ngjC_



not modelled 96.4 12 PDB header:lyase
Chain: C: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica
64d1d9ea_



not modelled 96.4 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I DAHP synthetase
65d1wbha1



not modelled 96.3 9 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
66c3b8iF_



not modelled 96.3 15 PDB header:lyase
Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase;
PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+.
67c3ng3A_



not modelled 96.3 16 PDB header:lyase
Chain: A: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of deoxyribose phosphate aldolase from mycobacterium2 avium 104 in a schiff base with an unknown aldehyde
68c2y85D_



not modelled 96.3 18 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
69d1ps9a1



not modelled 96.3 12 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
70d1ujqa_



not modelled 96.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like
71c3bg3B_



not modelled 96.2 23 PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial;
PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus)
72d1tqxa_



not modelled 96.2 9 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
73c2htmB_



not modelled 96.2 15 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
74d1n7ka_



not modelled 96.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
75c3g8rA_



not modelled 96.2 21 PDB header:biosynthetic protein
Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e;
PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472
76c2z6jB_



not modelled 96.2 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
77c2zyfA_



not modelled 96.2 16 PDB header:transferase
Chain: A: PDB Molecule:homocitrate synthase;
PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate
78d1vhca_



not modelled 96.1 18 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
79c3gnnA_



not modelled 96.1 20 PDB header:transferase
Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei
80c3pg8B_



not modelled 96.1 14 PDB header:transferase
Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase;
PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima
81d1w0ma_



not modelled 96.1 21 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
82d1ujpa_



not modelled 96.1 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
83c2qjhH_



not modelled 96.1 15 PDB header:lyase
Chain: H: PDB Molecule:putative aldolase mj0400;
PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate
84d1o60a_



not modelled 96.1 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I DAHP synthetase
85d1rpxa_



not modelled 96.1 25 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
86c3tqvA_



not modelled 96.1 21 PDB header:transferase
Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis.
87c2h6rG_



not modelled 96.1 20 PDB header:isomerase
Chain: G: PDB Molecule:triosephosphate isomerase;
PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
88c1ydoC_



not modelled 96.0 16 PDB header:lyase
Chain: C: PDB Molecule:hmg-coa lyase;
PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181.
89c3inpA_



96.0 14 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
90c3labA_



not modelled 96.0 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
91c2yw3E_



not modelled 96.0 20 PDB header:lyase
Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-
PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
92c2nx9B_



not modelled 96.0 18 PDB header:lyase
Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha;
PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae
93c3r2gA_



not modelled 95.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
94d1h1ya_



not modelled 95.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
95c2z1kA_



not modelled 95.9 21 PDB header:hydrolase
Chain: A: PDB Molecule:(neo)pullulanase;
PDBTitle: crystal structure of ttha1563 from thermus thermophilus hb8
96d1rvga_



not modelled 95.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
97c3pajA_



not modelled 95.9 23 PDB header:transferase
Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating;
PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961
98c1zfjA_



not modelled 95.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
99c2w6rA_



not modelled 95.8 23 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
100c1qpoA_



not modelled 95.8 12 PDB header:transferase
Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase;
PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis
101c3b0vD_



not modelled 95.8 12 PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna
102c3l0gD_



not modelled 95.8 8 PDB header:transferase
Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution
103d1ka9f_



not modelled 95.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
104c3navB_



not modelled 95.7 20 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
105c1qhoA_



not modelled 95.7 24 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-amylase;
PDBTitle: five-domain alpha-amylase from bacillus stearothermophilus,2 maltose/acarbose complex
106c3elfA_



not modelled 95.7 10 PDB header:lyase
Chain: A: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase
107d1eepa_



not modelled 95.7 12 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
108c2hjpA_



not modelled 95.7 13 PDB header:hydrolase
Chain: A: PDB Molecule:phosphonopyruvate hydrolase;
PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++
109c1o4uA_



not modelled 95.7 16 PDB header:transferase
Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase;
PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution
110c3thaB_



not modelled 95.7 14 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
111c2jbmA_



not modelled 95.7 20 PDB header:transferase
Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: qprtase structure from human
112d1qpoa1



not modelled 95.7 11 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
113d1qopa_



not modelled 95.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
114c2v5jB_



not modelled 95.6 11 PDB header:lyase
Chain: B: PDB Molecule:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase;
PDBTitle: apo class ii aldolase hpch
115d2flia1



not modelled 95.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
116c2h90A_



not modelled 95.6 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
117d1u5ha_



not modelled 95.5 18 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:HpcH/HpaI aldolase
118c3bmwA_



not modelled 95.5 22 PDB header:transferase
Chain: A: PDB Molecule:cyclomaltodextrin glucanotransferase;
PDBTitle: cyclodextrin glycosyl transferase from thermoanerobacterium2 thermosulfurigenes em1 mutant s77p complexed with a maltoheptaose3 inhibitor
119c3cixA_



not modelled 95.5 13 PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate
120c2gjlA_



not modelled 95.5 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0