Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ8TC17
DateWed May 9 18:06:35 BST 2012
Unique Job ID720af997498db0f1

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2fo0A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
Confidence and coverage
Confidence:100.0% Coverage: 91%
107 residues ( 91% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
Secondary structure 































SS confidence 



























































Disorder  ??










???









































??
Disorder confidence 



























































 
   .........70.........80.........90.........100.........110........
Sequence  YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNNRAQRGPCLGPKSHSRLG
Secondary structure 






























SS confidence 

























































Disorder  ??????
???


?????????



















??????????



??
Disorder confidence 

























































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2fo0 chain A

3D model

Region: 3 - 117
Aligned: 107
Modelled: 111
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 1opl chain A

3D model

Region: 3 - 117
Aligned: 107
Modelled: 115
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 1y57 chain A

3D model

Region: 3 - 117
Aligned: 113
Modelled: 115
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 1k9a chain B

3D model

Region: 1 - 117
Aligned: 109
Modelled: 117
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 2h8h chain A

3D model

Region: 2 - 117
Aligned: 114
Modelled: 116
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2

PDB 2c0i chain A

3D model

Region: 3 - 117
Aligned: 113
Modelled: 115
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 3nhn chain A

3D model

Region: 3 - 117
Aligned: 113
Modelled: 115
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region

Phyre2

PDB 2abl chain A

3D model

Region: 3 - 117
Aligned: 107
Modelled: 108
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase

Phyre2

PDB 1x27 chain F

3D model

Region: 3 - 117
Aligned: 113
Modelled: 115
Confidence: 100.0%
Identity: 37%
PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas

Phyre2

PDB 1g83 chain A

3D model

Region: 3 - 117
Aligned: 113
Modelled: 115
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2

Phyre2

PDB 1gri chain A

3D model

Region: 1 - 117
Aligned: 104
Modelled: 117
Confidence: 99.9%
Identity: 61%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 2azs chain A

3D model

Region: 1 - 59
Aligned: 59
Modelled: 59
Confidence: 99.8%
Identity: 61%
PDB header:signaling protein
Chain: A: PDB Molecule:sh2-sh3 adapter protein drk;
PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints)

Phyre2

PDB 2yt6 chain A

3D model

Region: 3 - 72
Aligned: 70
Modelled: 70
Confidence: 99.8%
Identity: 34%
PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1

Phyre2

PDB 1gbr chain A

3D model

Region: 1 - 61
Aligned: 61
Modelled: 61
Confidence: 99.8%
Identity: 66%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 2j6k chain E

3D model

Region: 1 - 57
Aligned: 57
Modelled: 57
Confidence: 99.8%
Identity: 23%
PDB header:protein binding
Chain: E: PDB Molecule:cd2-associated protein;
PDBTitle: n-terminal sh3 domain of cms (cd2ap human homolog)

Phyre2

PDB 1mv3 chain A

3D model

Region: 2 - 57
Aligned: 56
Modelled: 56
Confidence: 99.8%
Identity: 25%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 2csq chain A

3D model

Region: 3 - 59
Aligned: 57
Modelled: 57
Confidence: 99.7%
Identity: 26%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2

Phyre2

PDB 2rqr chain A

3D model

Region: 2 - 57
Aligned: 56
Modelled: 56
Confidence: 99.7%
Identity: 27%
PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex

Phyre2

PDB 1ng2 chain A domain 2

3D model

Region: 2 - 59
Aligned: 57
Modelled: 58
Confidence: 99.7%
Identity: 23%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 2jxb chain A

3D model

Region: 2 - 56
Aligned: 54
Modelled: 55
Confidence: 99.7%
Identity: 24%
PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex

Phyre2
1

c2fo0A_
2

c1oplA_
3

c1y57A_
4

c1k9aB_
5

c2h8hA_
6

c2c0iA_
7

c3nhnA_
8

c2ablA_
9

c1x27F_
10

c1g83A_
11

c1griA_
12

c2azsA_
13

c2yt6A_
14

d1gbra_
15

c2j6kE_
16

c1mv3A_
17

c2csqA_
18

c2rqrA_
19

d1ng2a2
20

c2jxbA_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139



140



141



142



143



144



145



146



147



148



149



150



151



152



153



154



155



156



157



158



159



160



161



162



163



164



165



166



167



168



169



170



171



172



173



174



175



176



177



178



179



180



181



182



183



184



185



186



187



188



189



190



191



192



193



194



195



196



197



198



199



200



201



202



203



204



205



206



207



208



209



210



211



212



213



214



215



216



217



218



219



220



221



222



223



224



225



226



227



228



229



230



231



232



233



234



235



236



237



238



239



240



241



242



243



244



245



246



247



248



249



250



251



252



253



254



255



256



257



258



259



260



261



262



263



264



265



266



267



268



269



270



271



272



273



274



275



276



277



278



279



280



281



282



283



284



285



286



287



288



289



290



291



292



293



294



295



296



297



298



299



300



301



302



303



304



305



306



307



308



309



310



311



312



313



314



315



316



317



318



319



320



321



322



323



324



325



326






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2fo0A_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
2c1oplA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
3c1y57A_



100.0 34 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
4c1k9aB_



100.0 43 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
5c2h8hA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
6c2c0iA_



100.0 34 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
7c3nhnA_



100.0 34 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
8c2ablA_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
9c1x27F_



100.0 37 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
10c1g83A_



100.0 36 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
11c1griA_



99.9 61 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
12c2azsA_



99.8 61 PDB header:signaling protein
Chain: A: PDB Molecule:sh2-sh3 adapter protein drk;
PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints)
13c2yt6A_



99.8 34 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
14d1gbra_



99.8 66 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
15c2j6kE_



99.8 23 PDB header:protein binding
Chain: E: PDB Molecule:cd2-associated protein;
PDBTitle: n-terminal sh3 domain of cms (cd2ap human homolog)
16c1mv3A_



99.8 25 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
17c2csqA_



99.7 26 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
18c2rqrA_



99.7 27 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
19d1ng2a2



99.7 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
20c2jxbA_



99.7 24 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
21c2oi3A_



not modelled 99.7 30 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
22c2egeA_



not modelled 99.7 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein kiaa1666;
PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
23c2kymA_



not modelled 99.7 32 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
24c2cudA_



not modelled 99.7 17 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
25c2dlpA_



not modelled 99.7 24 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
26c1x6gA_



not modelled 99.7 28 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
27c1x43A_



not modelled 99.7 23 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
28d2fo0a1



not modelled 99.7 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
29c3nmzD_



not modelled 99.7 21 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
30c2i0nA_



not modelled 99.7 21 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
31c2kbtA_



not modelled 99.7 33 PDB header:signaling protein
Chain: A: PDB Molecule:chimera of proto-oncogene vav, linker,
PDBTitle: attachment of an nmr-invisible solubility enhancement tag2 (inset) using a sortase-mediated protein ligation method
32d1opka1



not modelled 99.7 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
33c2bz8B_



not modelled 99.7 26 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
34c2d8hA_



not modelled 99.7 33 PDB header:unknown function
Chain: A: PDB Molecule:sh3yl1 protein;
PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1
35c2ct4A_



not modelled 99.7 26 PDB header:signaling protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: solution strutcure of the sh3 domain of the cdc42-2 interacting protein 4
36d1uffa_



not modelled 99.7 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
37d1cska_



not modelled 99.7 45 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
38d1k9aa1



not modelled 99.7 44 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
39c2fpeB_



not modelled 99.7 21 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
40c2dl5A_



not modelled 99.7 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:kiaa0769 protein;
PDBTitle: solution structure of the first sh3 domain of human2 kiaa0769 protein
41c2csiA_



not modelled 99.7 36 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the third sh3 domain of human rim-2 binding protein 2
42c2j06B_



not modelled 99.7 22 PDB header:signal transduction
Chain: B: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution
43d1ov3a2



not modelled 99.7 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
44c3qwxX_



not modelled 99.7 25 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
45c1zukA_



not modelled 99.7 23 PDB header:contractile protein
Chain: A: PDB Molecule:myosin tail region-interacting protein mti1;
PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17
46c1wxtA_



not modelled 99.7 28 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein flj21522;
PDBTitle: solution structure of the sh3 domain of human hypothetical2 protein flj21522
47c2d1xD_



not modelled 99.7 34 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
48d1wiea_



not modelled 99.7 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
49c2a28D_



not modelled 99.7 26 PDB header:signaling protein
Chain: D: PDB Molecule:bzz1 protein;
PDBTitle: atomic-resolution crystal structure of the second sh32 domain of yeast bzz1 determined from a pseudomerohedrally3 twinned crystal
50d1ugva_



not modelled 99.7 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
51c2yupA_



not modelled 99.7 28 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
52c3qwyA_



not modelled 99.7 26 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
53c1x2qA_



not modelled 99.7 29 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
54c1s1nA_



not modelled 99.7 28 PDB header:cell adhesion
Chain: A: PDB Molecule:nephrocystin 1;
PDBTitle: sh3 domain of human nephrocystin
55c1w1fA_



not modelled 99.7 36 PDB header:sh3-domain
Chain: A: PDB Molecule:tyrosine-protein kinase lyn;
PDBTitle: sh3 domain of human lyn tyrosine kinase
56c2dl8A_



not modelled 99.7 30 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
57c1x6bA_



not modelled 99.7 22 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
58d1qcfa1



not modelled 99.7 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
59c2dl7A_



not modelled 99.7 32 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:kiaa0769 protein;
PDBTitle: solution structure of the second sh3 domain of human2 kiaa0769 protein
60d1gl5a_



not modelled 99.7 39 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
61c2jteA_



not modelled 99.7 30 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: third sh3 domain of cd2ap
62c3rebD_



not modelled 99.7 30 PDB header:protein binding
Chain: D: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: hiv-1 nef protein in complex with engineered hck-sh3 domain
63c2creA_



not modelled 99.7 37 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hef-like protein;
PDBTitle: solution structure of rsgi ruh-036, an sh3 domain from2 human cdna
64c2ysqA_



not modelled 99.7 24 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
65c2egaA_



not modelled 99.7 18 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the first sh3 domain from human2 kiaa0418 protein
66c2epdA_



not modelled 99.7 29 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
67c2yunA_



not modelled 99.7 37 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
68c2js0A_



not modelled 99.7 25 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of second sh3 domain of adaptor nck
69c2dmoA_



not modelled 99.7 23 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
70c2ekhA_



not modelled 99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
71c2jw4A_



not modelled 99.7 28 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: nmr solution structure of the n-terminal sh3 domain of2 human nckalpha
72c2cubA_



not modelled 99.7 22 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
73c2k2mA_



not modelled 99.7 31 PDB header:signaling protein
Chain: A: PDB Molecule:eps8-like protein 1;
PDBTitle: structural basis of pxxdy motif recognition in sh3 binding
74c1wxbA_



not modelled 99.7 29 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:epidermal growth factor receptor pathway
PDBTitle: solution structure of the sh3 domain from human epidermal2 growth factor receptor pathway substrate 8-like protein
75d1uhca_



not modelled 99.7 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
76c2dm1A_



not modelled 99.7 33 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the second sh3 domain of human2 protein vav-2
77c1wx6A_



not modelled 99.7 29 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:cytoplasmic protein nck2;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2
78c1x2pA_



not modelled 99.7 29 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 2;
PDBTitle: solution structure of the sh3 domain of the protein2 arginine n-methyltransferase 2
79c2eqiA_



not modelled 99.7 27 PDB header:immune system, hydrolase
Chain: A: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2
80d2iima1



not modelled 99.7 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
81c2df6A_



not modelled 99.7 35 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
82c1w70A_



not modelled 99.7 25 PDB header:sh3 domain
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
83d1bu1a_



not modelled 99.7 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
84c2x3wD_



not modelled 99.7 39 PDB header:endocytosis
Chain: D: PDB Molecule:protein kinase c and casein kinase substrate in neurons
PDBTitle: structure of mouse syndapin i (crystal form 2)
85c1x69A_



not modelled 99.7 34 PDB header:signaling protein
Chain: A: PDB Molecule:cortactin isoform a;
PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin
86c2ct3A_



not modelled 99.7 24 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
87c2enmA_



not modelled 99.7 22 PDB header:endocytosis
Chain: A: PDB Molecule:sorting nexin-9;
PDBTitle: solution structure of the sh3 domain from mouse sorting2 nexin-9
88d1spka_



not modelled 99.7 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
89c2eyyA_



not modelled 99.7 30 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
90d1ug1a_



not modelled 99.7 17 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
91c2k6dA_



not modelled 99.7 29 PDB header:sh3 domain/ubiquitin
Chain: A: PDB Molecule:sh3 domain-containing kinase-binding protein 1;
PDBTitle: cin85 sh3-c domain in complex with ubiquitin
92d1qlya_



not modelled 99.7 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
93c1zuyB_



not modelled 99.7 30 PDB header:contractile protein
Chain: B: PDB Molecule:myosin-5 isoform;
PDBTitle: high-resolution structure of yeast myo5 sh3 domain
94d1uj0a_



not modelled 99.7 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
95c2lcsA_



not modelled 99.7 22 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:nap1-binding protein 2;
PDBTitle: yeast nbp2p sh3 domain in complex with a peptide from ste20p
96d1k4us_



not modelled 99.7 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
97c2xmfA_



not modelled 99.7 35 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
98c1z9zA_



not modelled 99.7 29 PDB header:structural protein
Chain: A: PDB Molecule:cytoskeleton assembly control protein sla1;
PDBTitle: crystal structure of yeast sla1 sh3 domain 3
99c2yuoA_



not modelled 99.7 30 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
100c2egcA_



not modelled 99.7 22 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structure of the fifth sh3 domain from human2 kiaa0418 protein
101c3rnjA_



not modelled 99.7 32 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)
102d1j3ta_



not modelled 99.7 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
103c2djqA_



not modelled 99.7 33 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
104c2cucA_



not modelled 99.7 28 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2
105d1i07a_



not modelled 99.7 34 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
106d2rn8a1



not modelled 99.7 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
107c2l0aA_



not modelled 99.7 35 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
108d1ycsb2



not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
109d1udla_



not modelled 99.6 34 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
110c2eczA_



not modelled 99.6 24 PDB header:signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain of sorbin and sh32 domain-containing protein 1
111c2rqvA_



not modelled 99.6 20 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of sh3ci domain of bem1p
112d1wfwa_



not modelled 99.6 14 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
113c2dl3A_



not modelled 99.6 28 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
114c2dl4A_



not modelled 99.6 28 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
115d1oota_



not modelled 99.6 42 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
116c2rf0D_



not modelled 99.6 26 PDB header:transferase
Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10;
PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
117c2drmB_



not modelled 99.6 35 PDB header:contractile protein
Chain: B: PDB Molecule:acanthamoeba myosin ib;
PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
118d1u5sa1



not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
119d1lcka1



not modelled 99.6 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
120c2nwmA_



not modelled 99.6 32 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite