Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ09746
DateSun Jul 8 11:56:56 BST 2012
Unique Job IDb0e8ecbef6aa74c1

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1griA_
Top template information
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
Confidence and coverage
Confidence:100.0% Coverage: 18%
116 residues ( 18% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
475 residues ( 74%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSLETYKFSDELHDDFKVVDSWINNGAKWLEDIQLYYKERSSIEKEYAQKLASLSNKYGE
Secondary structure 



SS confidence 



























































Disorder  ???????



















































?
Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  KKSRKSSALSVGDTPAMSAGSLECASLTTWSKILDELTRSSKTHQKLSDDYSLDIAEKLK
Secondary structure 












SS confidence 



























































Disorder  ????????????????????????



































Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  KLESHIEALRKVYDDLYKKFSSEKETLLNSVKRAKVSYHEACDDLESARQKNDKYREQKT
Secondary structure 
SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  QRNLKLSESDMLDKKNKYLLRMLVYNAHKQKFYNETLPTLLNHMQVLNEYRVSNLNEIWC
Secondary structure 
SS confidence 



























































Disorder 












?













































Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  NSFSIEKSLHDTLSQRTVEIQSEIAKNEPVLDSAMFGRHNSKNWALPADLHFEPSPIWHD
Secondary structure 






















SS confidence 



























































Disorder 







































???????








????
Disorder confidence 



























































 
   .........310.........320.........330.........340.........350.........360
Sequence  TDALVVDGSCKNYLRNLLVHSKNDLGKQKGELVSLDSQLEGLRVDDPNSANQSFESKKAS
Secondary structure 








SS confidence 



























































Disorder  ????????


















?????







???????


??????????
Disorder confidence 



























































 
   .........370.........380.........390.........400.........410.........420
Sequence  INLEGKELMVKARIEDLEVRINKITSVANNLEEGGRFHDFKHVSFKLPTSCSYCREIIWG
Secondary structure 






























SS confidence 



























































Disorder 
????????????









?
????????????





??














Disorder confidence 



























































 
   .........430.........440.........450.........460.........470.........480
Sequence  LSKRGCVCKNCGFKCHARCELLVPANCKNGEPEVADDDAVDTSVTATDDFDASASSSNAY
Secondary structure 



















































SS confidence 



























































Disorder 
























???????












???????????????
Disorder confidence 



























































 
   .........490.........500.........510.........520.........530.........540
Sequence  ESYRNTYTDDMDSSSIYQTSLSNVKTEETTPAEPASKVDGVVLYDFTGEHEGVITASEGQ
Secondary structure 

























































SS confidence 



























































Disorder  ????

?







???????????????













?

?
???????


?
Disorder confidence 



























































 
   .........550.........560.........570.........580.........590.........600
Sequence  EFTLLEPDDGSGWVRVKIDGTDGLIPASYVKLNDELNTSVTLDGDSSYVKALYAYTAQSD
Secondary structure 













































SS confidence 



























































Disorder 








??
?




????
?

?
???????
??

















?

?
Disorder confidence 



























































 
   .........610.........620.........630.........640..
Sequence  MELSIQEGDIIQVTNRNAGNGWSEGILNGVTGQFPANYVTDV
Secondary structure 



















SS confidence 









































Disorder  ?






































??
Disorder confidence 









































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1gri chain A

3D model

Region: 520 - 642
Aligned: 116
Modelled: 123
Confidence: 100.0%
Identity: 37%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 2efl chain A domain 1

3D model

Region: 7 - 296
Aligned: 271
Modelled: 271
Confidence: 99.9%
Identity: 21%
Fold: BAR/IMD domain-like
Superfamily: BAR/IMD domain-like
Family: FCH domain

Phyre2

PDB 2lqn chain A

3D model

Region: 486 - 642
Aligned: 156
Modelled: 157
Confidence: 99.9%
Identity: 26%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2eyz chain A

3D model

Region: 485 - 642
Aligned: 157
Modelled: 158
Confidence: 99.9%
Identity: 20%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 2efk chain A domain 1

3D model

Region: 15 - 296
Aligned: 263
Modelled: 263
Confidence: 99.9%
Identity: 20%
Fold: BAR/IMD domain-like
Superfamily: BAR/IMD domain-like
Family: FCH domain

Phyre2

PDB 1ng2 chain A

3D model

Region: 519 - 642
Aligned: 122
Modelled: 124
Confidence: 99.9%
Identity: 25%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2

PDB 1ov3 chain A

3D model

Region: 510 - 641
Aligned: 130
Modelled: 132
Confidence: 99.9%
Identity: 25%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 2l3s chain A

3D model

Region: 520 - 642
Aligned: 122
Modelled: 123
Confidence: 99.9%
Identity: 25%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 1mv3 chain A

3D model

Region: 447 - 642
Aligned: 196
Modelled: 196
Confidence: 99.9%
Identity: 18%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 3m3w chain A

3D model

Region: 7 - 294
Aligned: 269
Modelled: 273
Confidence: 99.9%
Identity: 19%
PDB header:endocytosis
Chain: A: PDB Molecule:protein kinase c and casein kinase ii substrate protein 3;
PDBTitle: crystal strcuture of mouse pacsin3 bar domain mutant

Phyre2

PDB 3i2w chain B

3D model

Region: 7 - 283
Aligned: 259
Modelled: 262
Confidence: 99.9%
Identity: 24%
PDB header:endocytosis
Chain: B: PDB Molecule:syndapin;
PDBTitle: crystal structure of efc/f-bar domain of drosophila2 syndapin/pacsin

Phyre2

PDB 2v0o chain B

3D model

Region: 1 - 295
Aligned: 269
Modelled: 276
Confidence: 99.9%
Identity: 17%
PDB header:lipid-binding protein
Chain: B: PDB Molecule:fch domain only protein 2;
PDBTitle: fcho2 f-bar domain

Phyre2

PDB 3haj chain A

3D model

Region: 7 - 289
Aligned: 265
Modelled: 268
Confidence: 99.9%
Identity: 20%
PDB header:endocytosis
Chain: A: PDB Molecule:human pacsin2 f-bar;
PDBTitle: crystal structure of human pacsin2 f-bar domain (p2121212 lattice)

Phyre2

PDB 3lll chain A

3D model

Region: 7 - 293
Aligned: 268
Modelled: 272
Confidence: 99.9%
Identity: 21%
PDB header:endocytosis
Chain: A: PDB Molecule:protein kinase c and casein kinase substrate in neurons
PDBTitle: crystal structure of mouse pacsin2 f-bar domain

Phyre2

PDB 3aco chain B

3D model

Region: 7 - 283
Aligned: 259
Modelled: 262
Confidence: 99.8%
Identity: 21%
PDB header:endocytosis
Chain: B: PDB Molecule:protein kinase c and casein kinase substrate in
PDBTitle: crystal structure of the efc/f-bar domain of human2 pacsin2/syndapin ii (2.7 a)

Phyre2

PDB 3hah chain A

3D model

Region: 7 - 294
Aligned: 263
Modelled: 273
Confidence: 99.8%
Identity: 17%
PDB header:endocytosis
Chain: A: PDB Molecule:human pacsin1 f-bar;
PDBTitle: crystal structure of human pacsin1 f-bar domain (c2 lattice)

Phyre2

PDB 3syv chain B

3D model

Region: 7 - 290
Aligned: 256
Modelled: 262
Confidence: 99.8%
Identity: 14%
PDB header:endocytosis
Chain: B: PDB Molecule:protein kinase c and casein kinase ii substrate protein 3;
PDBTitle: crystal structure of mpacsin 3 f-bar domain mutant

Phyre2

PDB 3qwe chain A

3D model

Region: 14 - 280
Aligned: 248
Modelled: 251
Confidence: 99.8%
Identity: 14%
PDB header:protein binding
Chain: A: PDB Molecule:gem-interacting protein;
PDBTitle: crystal structure of the n-terminal domain of the gem interacting2 protein

Phyre2

PDB 1udl chain A

3D model

Region: 558 - 642
Aligned: 84
Modelled: 85
Confidence: 99.8%
Identity: 39%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 1ng2 chain A domain 2

3D model

Region: 573 - 642
Aligned: 69
Modelled: 70
Confidence: 99.7%
Identity: 26%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2
1

c1griA_
2

d2efla1
3

c2lqnA_
4

c2eyzA_
5

d2efka1
6

c1ng2A_
7

c1ov3A_
8

c2l3sA_
9

c1mv3A_
10

c3m3wA_
11

c3i2wB_
12

c2v0oB_
13

c3hajA_
14

c3lllA_
15

c3acoB_
16

c3hahA_
17

c3syvB_
18

c3qweA_
19

d1udla_
20

d1ng2a2
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122



123



124



125



126



127



128



129



130



131



132



133



134



135



136



137



138



139



140



141



142



143



144



145



146



147



148



149



150



151



152



153



154



155



156



157



158



159



160



161



162



163



164



165



166



167



168



169



170



171



172



173



174



175



176



177



178



179



180



181



182



183



184



185



186



187



188



189



190



191



192



193



194



195



196



197



198



199



200



201



202



203



204



205



206



207



208



209



210



211



212



213



214



215



216



217



218



219



220



221



222



223



224



225



226



227



228



229



230



231



232



233



234



235



236



237



238



239



240



241



242



243



244



245



246



247



248



249



250



251



252



253



254



255



256



257



258



259



260



261



262



263



264



265



266



267



268



269



270



271



272



273



274



275



276



277



278



279



280



281



282



283



284



285



286



287



288



289



290



291



292



293



294



295



296



297



298



299



300



301



302



303



304



305



306



307



308



309



310



311



312



313



314



315



316



317



318



319



320



321



322



323



324



325



326



327



328



329






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1griA_



100.0 37 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
2d2efla1



99.9 21 Fold:BAR/IMD domain-like
Superfamily:BAR/IMD domain-like
Family:FCH domain
3c2lqnA_



99.9 26 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
4c2eyzA_



99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
5d2efka1



99.9 20 Fold:BAR/IMD domain-like
Superfamily:BAR/IMD domain-like
Family:FCH domain
6c1ng2A_



99.9 25 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
7c1ov3A_



99.9 25 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
8c2l3sA_



99.9 25 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
9c1mv3A_



99.9 18 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
10c3m3wA_



99.9 19 PDB header:endocytosis
Chain: A: PDB Molecule:protein kinase c and casein kinase ii substrate protein 3;
PDBTitle: crystal strcuture of mouse pacsin3 bar domain mutant
11c3i2wB_



99.9 24 PDB header:endocytosis
Chain: B: PDB Molecule:syndapin;
PDBTitle: crystal structure of efc/f-bar domain of drosophila2 syndapin/pacsin
12c2v0oB_



99.9 17 PDB header:lipid-binding protein
Chain: B: PDB Molecule:fch domain only protein 2;
PDBTitle: fcho2 f-bar domain
13c3hajA_



99.9 20 PDB header:endocytosis
Chain: A: PDB Molecule:human pacsin2 f-bar;
PDBTitle: crystal structure of human pacsin2 f-bar domain (p2121212 lattice)
14c3lllA_



99.9 21 PDB header:endocytosis
Chain: A: PDB Molecule:protein kinase c and casein kinase substrate in neurons
PDBTitle: crystal structure of mouse pacsin2 f-bar domain
15c3acoB_



99.8 21 PDB header:endocytosis
Chain: B: PDB Molecule:protein kinase c and casein kinase substrate in
PDBTitle: crystal structure of the efc/f-bar domain of human2 pacsin2/syndapin ii (2.7 a)
16c3hahA_



99.8 17 PDB header:endocytosis
Chain: A: PDB Molecule:human pacsin1 f-bar;
PDBTitle: crystal structure of human pacsin1 f-bar domain (c2 lattice)
17c3syvB_



99.8 14 PDB header:endocytosis
Chain: B: PDB Molecule:protein kinase c and casein kinase ii substrate protein 3;
PDBTitle: crystal structure of mpacsin 3 f-bar domain mutant
18c3qweA_



99.8 14 PDB header:protein binding
Chain: A: PDB Molecule:gem-interacting protein;
PDBTitle: crystal structure of the n-terminal domain of the gem interacting2 protein
19d1udla_



99.8 39 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
20d1ng2a2



99.7 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
21c2csqA_



not modelled 99.7 24 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
22c2dx1A_



not modelled 99.7 32 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
23c2dlpA_



not modelled 99.7 32 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
24c2egeA_



not modelled 99.7 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein kiaa1666;
PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
25c2eyyA_



not modelled 99.7 21 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
26d1ov3a2



not modelled 99.7 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
27c3g9gA_



not modelled 99.7 13 PDB header:endocytosis
Chain: A: PDB Molecule:suppressor of yeast profilin deletion;
PDBTitle: crystal structure of the n-terminal efc/f-bar domain of syp1
28c3rnjA_



not modelled 99.7 30 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)
29c1x6gA_



not modelled 99.7 13 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
30c3nmzD_



not modelled 99.7 27 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
31c2df6A_



not modelled 99.7 41 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
32c3qwyA_



not modelled 99.7 20 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
33c2rqrA_



not modelled 99.7 19 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
34c1x43A_



not modelled 99.7 20 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
35c2kbtA_



not modelled 99.7 39 PDB header:signaling protein
Chain: A: PDB Molecule:chimera of proto-oncogene vav, linker,
PDBTitle: attachment of an nmr-invisible solubility enhancement tag2 (inset) using a sortase-mediated protein ligation method
36c2xmfA_



not modelled 99.7 45 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
37c2e5kA_



not modelled 99.7 29 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
38c2csiA_



not modelled 99.7 32 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the third sh3 domain of human rim-2 binding protein 2
39d1wiea_



not modelled 99.7 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
40c2cubA_



not modelled 99.7 29 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
41d1gcqa_



not modelled 99.7 46 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
42c2ed0A_



not modelled 99.6 42 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
43d1sema_



not modelled 99.6 37 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
44c2nwmA_



not modelled 99.6 36 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
45d1bb9a_



not modelled 99.6 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
46c1bb9A_



not modelled 99.6 31 PDB header:transferase
Chain: A: PDB Molecule:amphiphysin 2;
PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2
47c2jxbA_



not modelled 99.6 26 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
48c2dbkA_



not modelled 99.6 28 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
49c2yuoA_



not modelled 99.6 29 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
50d1k4us_



not modelled 99.6 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
51c2dl7A_



not modelled 99.6 41 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:kiaa0769 protein;
PDBTitle: solution structure of the second sh3 domain of human2 kiaa0769 protein
52c2djqA_



not modelled 99.6 29 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
53d1utia_



not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
54c2dmoA_



not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
55c1x2qA_



not modelled 99.6 30 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
56c2l0aA_



not modelled 99.6 30 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
57d1wlpb2



not modelled 99.6 20 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
58d1oota_



not modelled 99.6 36 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
59c2yunA_



not modelled 99.6 37 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
60d1gria2



not modelled 99.6 45 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
61c1zlmA_



not modelled 99.6 39 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
62c3qwxX_



not modelled 99.6 22 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
63d1uuea_



not modelled 99.6 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
64c2eyxA_



not modelled 99.6 26 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
65c2ebpA_



not modelled 99.6 24 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
66d1ugva_



not modelled 99.6 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
67c1zx6A_



not modelled 99.6 43 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
68d1spka_



not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
69d1uhca_



not modelled 99.6 22 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
70c2bz8B_



not modelled 99.6 39 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
71c2fpeB_



not modelled 99.6 28 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
72c2j6kE_



not modelled 99.6 40 PDB header:protein binding
Chain: E: PDB Molecule:cd2-associated protein;
PDBTitle: n-terminal sh3 domain of cms (cd2ap human homolog)
73c1w70A_



not modelled 99.6 35 PDB header:sh3 domain
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
74d1pwta_



not modelled 99.6 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
75c2dnuA_



not modelled 99.6 22 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
76d1ujya_



not modelled 99.6 42 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
77d1u06a1



not modelled 99.6 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
78c2ysqA_



not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
79c1x69A_



not modelled 99.6 32 PDB header:signaling protein
Chain: A: PDB Molecule:cortactin isoform a;
PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin
80c2a28D_



not modelled 99.6 45 PDB header:signaling protein
Chain: D: PDB Molecule:bzz1 protein;
PDBTitle: atomic-resolution crystal structure of the second sh32 domain of yeast bzz1 determined from a pseudomerohedrally3 twinned crystal
81d1uj0a_



not modelled 99.6 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
82d1phta_



not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
83d1i1ja_



not modelled 99.6 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
84c1wyxA_



not modelled 99.6 38 PDB header:cell adhesion
Chain: A: PDB Molecule:crk-associated substrate;
PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
85c2i0nA_



not modelled 99.6 29 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
86d1oeba_



not modelled 99.6 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
87c1zukA_



not modelled 99.6 22 PDB header:contractile protein
Chain: A: PDB Molecule:myosin tail region-interacting protein mti1;
PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17
88c2d1xD_



not modelled 99.6 40 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
89c2pqhA_



not modelled 99.6 33 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: structure of sh3 chimera with a type ii ligand linked to the chain c-2 terminal
90c2drmB_



not modelled 99.6 52 PDB header:contractile protein
Chain: B: PDB Molecule:acanthamoeba myosin ib;
PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
91d1jqqa_



not modelled 99.6 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
92d2v1ra1



not modelled 99.6 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
93d1nega_



not modelled 99.6 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
94c1negA_



not modelled 99.6 33 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin
95c2cudA_



not modelled 99.6 21 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
96c2rf0D_



not modelled 99.6 38 PDB header:transferase
Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10;
PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
97d1u5sa1



not modelled 99.6 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
98c2dl4A_



not modelled 99.6 27 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
99c2oi3A_



not modelled 99.6 27 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
100d1gbra_



not modelled 99.6 34 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
101d1e6ga_



not modelled 99.6 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
102c2kt1A_



not modelled 99.6 29 PDB header:protein binding
Chain: A: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: solution nmr structure of the sh3 domain from the p85beta2 subunit of phosphatidylinositol 3-kinase from h.sapiens,3 northeast structural genomics consortium target hr5531e
103c1x6bA_



not modelled 99.6 26 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
104c2yt6A_



not modelled 99.6 30 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
105c2ke9A_



not modelled 99.6 28 PDB header:protein binding
Chain: A: PDB Molecule:caskin-2;
PDBTitle: nmr solution structure of the caskin sh3 domain
106c2kymA_



not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
107c2epdA_



not modelled 99.6 30 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
108c2krnA_



not modelled 99.6 34 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: high resolution structure of the second sh3 domain of cd2ap
109c2ed1A_



not modelled 99.6 29 PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
110c2azsA_



not modelled 99.6 28 PDB header:signaling protein
Chain: A: PDB Molecule:sh2-sh3 adapter protein drk;
PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints)
111c2jteA_



not modelled 99.6 36 PDB header:signaling protein
Chain: A: PDB Molecule:cd2-associated protein;
PDBTitle: third sh3 domain of cd2ap
112d1uffa_



not modelled 99.6 41 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
113d1cska_



not modelled 99.6 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
114c2dbmA_



not modelled 99.6 39 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:sh3-containing grb2-like protein 2;
PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2
115c2ct3A_



not modelled 99.6 32 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
116d1e6ha_



not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
117d1ycsb2



not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
118c2k6dA_



not modelled 99.6 45 PDB header:sh3 domain/ubiquitin
Chain: A: PDB Molecule:sh3 domain-containing kinase-binding protein 1;
PDBTitle: cin85 sh3-c domain in complex with ubiquitin
119c2dilA_



not modelled 99.6 32 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
120c4esrB_



not modelled 99.6 44 PDB header:protein binding
Chain: B: PDB Molecule:jouberin;
PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite