Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP75764
DateThu Jan 5 12:13:53 GMT 2012
Unique Job IDffd62f2f397f0755

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2b3yB_
Top template information
PDB header:lyase
Chain: B: PDB Molecule:iron-responsive element binding protein 1;
PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1)
Confidence and coverage
Confidence:100.0% Coverage: 93%
702 residues ( 93% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDS
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Disorder  ?

?????


????????????????????????









??
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   .........70.........80.........90.........100.........110.........120
Sequence  LASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGG
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   .........130.........140.........150.........160.........170.........180
Sequence  IFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDI
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   .........190.........200.........210.........220.........230.........240
Sequence  DYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVSALSTDFRNSV
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   .........250.........260.........270.........280.........290.........300
Sequence  DVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIA
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   .........310.........320.........330.........340.........350.........360
Sequence  LPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGC
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????????????????
?
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   .........370.........380.........390.........400.........410.........420
Sequence  SGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAF
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?
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   .........430.........440.........450.........460.........470.........480
Sequence  CGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLT
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?????????




























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   .........490.........500.........510.........520.........530.........540
Sequence  SASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLK
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????????????



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?
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   .........550.........560.........570.........580.........590.........600
Sequence  VCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVSRSKATAELENQRLAG
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??????





















??
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   .........610.........620.........630.........640.........650.........660
Sequence  NVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIA
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   .........670.........680.........690.........700.........710.........720
Sequence  EEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAP
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???

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   .........730.........740.........750...
Sequence  VTEITLYMESLTAEEREIIKAGSLINFNKNRQM
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???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2b3y chain B

3D model

Region: 38 - 752
Aligned: 702
Modelled: 715
Confidence: 100.0%
Identity: 22%
PDB header:lyase
Chain: B: PDB Molecule:iron-responsive element binding protein 1;
PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1)

Phyre2

PDB 5acn chain A

3D model

Region: 33 - 752
Aligned: 668
Modelled: 668
Confidence: 100.0%
Identity: 24%
PDB header:lyase(carbon-oxygen)
Chain: A: PDB Molecule:aconitase;
PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal

Phyre2

PDB 2b3y chain A domain 2

3D model

Region: 38 - 534
Aligned: 492
Modelled: 497
Confidence: 100.0%
Identity: 23%
Fold: Aconitase iron-sulfur domain
Superfamily: Aconitase iron-sulfur domain
Family: Aconitase iron-sulfur domain

Phyre2

PDB 1aco chain A domain 2

3D model

Region: 33 - 505
Aligned: 441
Modelled: 448
Confidence: 100.0%
Identity: 26%
Fold: Aconitase iron-sulfur domain
Superfamily: Aconitase iron-sulfur domain
Family: Aconitase iron-sulfur domain

Phyre2

PDB 1l5j chain A domain 3

3D model

Region: 28 - 509
Aligned: 428
Modelled: 444
Confidence: 100.0%
Identity: 22%
Fold: Aconitase iron-sulfur domain
Superfamily: Aconitase iron-sulfur domain
Family: Aconitase iron-sulfur domain

Phyre2

PDB 1l5j chain B

3D model

Region: 28 - 512
Aligned: 438
Modelled: 452
Confidence: 100.0%
Identity: 21%
PDB header:lyase
Chain: B: PDB Molecule:aconitate hydratase 2;
PDBTitle: crystal structure of e. coli aconitase b.

Phyre2

PDB 2b3y chain A domain 1

3D model

Region: 506 - 752
Aligned: 240
Modelled: 247
Confidence: 100.0%
Identity: 19%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: LeuD/IlvD-like
Family: LeuD-like

Phyre2

PDB 1aco chain A domain 1

3D model

Region: 509 - 752
Aligned: 219
Modelled: 228
Confidence: 100.0%
Identity: 21%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: LeuD/IlvD-like
Family: LeuD-like

Phyre2

PDB 1v7l chain A

3D model

Region: 545 - 751
Aligned: 149
Modelled: 152
Confidence: 100.0%
Identity: 24%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: LeuD/IlvD-like
Family: LeuD-like

Phyre2

PDB 2pkp chain A

3D model

Region: 545 - 753
Aligned: 151
Modelled: 154
Confidence: 100.0%
Identity: 28%
PDB header:lyase
Chain: A: PDB Molecule:homoaconitase small subunit;
PDBTitle: crystal structure of 3-isopropylmalate dehydratase (leud)2 from methhanocaldococcus jannaschii dsm2661 (mj1271)

Phyre2

PDB 1l5j chain A domain 2

3D model

Region: 532 - 753
Aligned: 178
Modelled: 182
Confidence: 100.0%
Identity: 20%
Fold: The "swivelling" beta/beta/alpha domain
Superfamily: LeuD/IlvD-like
Family: LeuD-like

Phyre2

PDB 2hcu chain A

3D model

Region: 541 - 742
Aligned: 152
Modelled: 167
Confidence: 100.0%
Identity: 20%
PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: crystal structure of smu.1381 (or leud) from streptococcus2 mutans

Phyre2

PDB 3q3w chain B

3D model

Region: 541 - 742
Aligned: 165
Modelled: 177
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: B: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: isopropylmalate isomerase small subunit from campylobacter jejuni.

Phyre2

PDB 3h5j chain A

3D model

Region: 541 - 742
Aligned: 157
Modelled: 167
Confidence: 100.0%
Identity: 18%
PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: leud_1-168 small subunit of isopropylmalate isomerase (rv2987c) from2 mycobacterium tuberculosis

Phyre2

PDB 1g4m chain A domain 1

3D model

Region: 655 - 684
Aligned: 30
Modelled: 30
Confidence: 86.9%
Identity: 23%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: E set domains
Family: Arrestin/Vps26-like

Phyre2

PDB 1cjy chain B

3D model

Region: 658 - 741
Aligned: 80
Modelled: 84
Confidence: 85.0%
Identity: 11%
PDB header:hydrolase
Chain: B: PDB Molecule:protein (cytosolic phospholipase a2);
PDBTitle: human cytosolic phospholipase a2

Phyre2

PDB 1cf1 chain A domain 1

3D model

Region: 655 - 684
Aligned: 29
Modelled: 30
Confidence: 80.3%
Identity: 14%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: E set domains
Family: Arrestin/Vps26-like

Phyre2

PDB 2k6z chain A

3D model

Region: 651 - 729
Aligned: 76
Modelled: 79
Confidence: 64.6%
Identity: 21%
PDB header:metal transport
Chain: A: PDB Molecule:putative uncharacterized protein ttha1943;
PDBTitle: solution structures of copper loaded form pcua (trans2 conformation of the peptide bond involving the nitrogen of3 p14)

Phyre2

PDB 1x9l chain A

3D model

Region: 651 - 729
Aligned: 76
Modelled: 79
Confidence: 54.5%
Identity: 16%
Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily: DR1885-like metal-binding protein
Family: DR1885-like metal-binding protein

Phyre2

PDB 3dc1 chain A

3D model

Region: 59 - 173
Aligned: 115
Modelled: 115
Confidence: 50.5%
Identity: 12%
PDB header:transferase
Chain: A: PDB Molecule:kynurenine/alpha-aminoadipate aminotransferase
PDBTitle: crystal structure of kynurenine aminotransferase ii complex with2 alpha-ketoglutarate

Phyre2
1

c2b3yB_
2

c5acnA_
3

d2b3ya2
4

d1acoa2
5

d1l5ja3
6

c1l5jB_
7

d2b3ya1
8

d1acoa1
9

d1v7la_
10

c2pkpA_
11

d1l5ja2
12

c2hcuA_
13

c3q3wB_
14

c3h5jA_
15

d1g4ma1
16

c1cjyB_
17

d1cf1a1
18

c2k6zA_
19

d1x9la_
20

c3dc1A_
21



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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2b3yB_



100.0 22 PDB header:lyase
Chain: B: PDB Molecule:iron-responsive element binding protein 1;
PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1)
2c5acnA_



100.0 24 PDB header:lyase(carbon-oxygen)
Chain: A: PDB Molecule:aconitase;
PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal
3d2b3ya2



100.0 23 Fold:Aconitase iron-sulfur domain
Superfamily:Aconitase iron-sulfur domain
Family:Aconitase iron-sulfur domain
4d1acoa2



100.0 26 Fold:Aconitase iron-sulfur domain
Superfamily:Aconitase iron-sulfur domain
Family:Aconitase iron-sulfur domain
5d1l5ja3



100.0 22 Fold:Aconitase iron-sulfur domain
Superfamily:Aconitase iron-sulfur domain
Family:Aconitase iron-sulfur domain
6c1l5jB_



100.0 21 PDB header:lyase
Chain: B: PDB Molecule:aconitate hydratase 2;
PDBTitle: crystal structure of e. coli aconitase b.
7d2b3ya1



100.0 19 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:LeuD/IlvD-like
Family:LeuD-like
8d1acoa1



100.0 21 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:LeuD/IlvD-like
Family:LeuD-like
9d1v7la_



100.0 24 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:LeuD/IlvD-like
Family:LeuD-like
10c2pkpA_



100.0 28 PDB header:lyase
Chain: A: PDB Molecule:homoaconitase small subunit;
PDBTitle: crystal structure of 3-isopropylmalate dehydratase (leud)2 from methhanocaldococcus jannaschii dsm2661 (mj1271)
11d1l5ja2



100.0 20 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:LeuD/IlvD-like
Family:LeuD-like
12c2hcuA_



100.0 20 PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: crystal structure of smu.1381 (or leud) from streptococcus2 mutans
13c3q3wB_



100.0 18 PDB header:transferase
Chain: B: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: isopropylmalate isomerase small subunit from campylobacter jejuni.
14c3h5jA_



100.0 18 PDB header:lyase
Chain: A: PDB Molecule:3-isopropylmalate dehydratase small subunit;
PDBTitle: leud_1-168 small subunit of isopropylmalate isomerase (rv2987c) from2 mycobacterium tuberculosis
15d1g4ma1



86.9 23 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Arrestin/Vps26-like
16c1cjyB_



85.0 11 PDB header:hydrolase
Chain: B: PDB Molecule:protein (cytosolic phospholipase a2);
PDBTitle: human cytosolic phospholipase a2
17d1cf1a1



80.3 14 Fold:Immunoglobulin-like beta-sandwich
Superfamily:E set domains
Family:Arrestin/Vps26-like
18c2k6zA_



64.6 21 PDB header:metal transport
Chain: A: PDB Molecule:putative uncharacterized protein ttha1943;
PDBTitle: solution structures of copper loaded form pcua (trans2 conformation of the peptide bond involving the nitrogen of3 p14)
19d1x9la_



54.5 16 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f
Superfamily:DR1885-like metal-binding protein
Family:DR1885-like metal-binding protein
20c3dc1A_



50.5 12 PDB header:transferase
Chain: A: PDB Molecule:kynurenine/alpha-aminoadipate aminotransferase
PDBTitle: crystal structure of kynurenine aminotransferase ii complex with2 alpha-ketoglutarate
21c2yx6C_



not modelled 42.3 10 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:hypothetical protein ph0822;
PDBTitle: crystal structure of ph0822
22c3l4gI_



not modelled 38.0 19 PDB header:ligase
Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain;
PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase
23d1rdua_



not modelled 37.0 10 Fold:Ribonuclease H-like motif
Superfamily:Nitrogenase accessory factor-like
Family:MTH1175-like
24d1t3va_



not modelled 34.5 15 Fold:Ribonuclease H-like motif
Superfamily:Nitrogenase accessory factor-like
Family:MTH1175-like
25c3bolB_



not modelled 30.7 16 PDB header:transferase
Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine
PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+
26d1o13a_



not modelled 30.5 11 Fold:Ribonuclease H-like motif
Superfamily:Nitrogenase accessory factor-like
Family:MTH1175-like
27d2r4qa1



not modelled 30.5 21 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Fructose specific IIB subunit-like
28d2q7wa1



not modelled 30.4 8 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:AAT-like
29d1yaaa_



not modelled 29.8 17 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:AAT-like
30c3mo4B_



not modelled 29.0 20 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-1,3/4-fucosidase;
PDBTitle: the crystal structure of an alpha-(1-3,4)-fucosidase from2 bifidobacterium longum subsp. infantis atcc 15697
31c3gzaB_



not modelled 25.8 24 PDB header:hydrolase
Chain: B: PDB Molecule:putative alpha-l-fucosidase;
PDBTitle: crystal structure of putative alpha-l-fucosidase (np_812709.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.60 a resolution
32c2yb1A_



not modelled 24.9 30 PDB header:hydrolase
Chain: A: PDB Molecule:amidohydrolase;
PDBTitle: structure of an amidohydrolase from chromobacterium violaceum (efi2 target efi-500202) with bound mn, amp and phosphate.
33d1t0tv_



not modelled 24.3 14 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Chlorite dismutase-like
34c2wbrA_



not modelled 23.6 31 PDB header:dna-binding protein
Chain: A: PDB Molecule:gw182;
PDBTitle: the rrm domain in gw182 proteins contributes to mirna-2 mediated gene silencing
35c2wvsD_



not modelled 23.1 20 PDB header:hydrolase
Chain: D: PDB Molecule:alpha-l-fucosidase;
PDBTitle: crystal structure of an alpha-l-fucosidase gh29 trapped2 covalent intermediate from bacteroides thetaiotaomicron in3 complex with 2-fluoro-fucosyl fluoride using an e288q4 mutant
36d2csta_



not modelled 22.1 13 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:AAT-like
37d1p90a_



not modelled 21.6 10 Fold:Ribonuclease H-like motif
Superfamily:Nitrogenase accessory factor-like
Family:Nitrogenase accessory factor
38d3bofa2



not modelled 21.6 29 Fold:TIM beta/alpha-barrel
Superfamily:Homocysteine S-methyltransferase
Family:Homocysteine S-methyltransferase
39c3qguB_



not modelled 20.8 22 PDB header:transferase
Chain: B: PDB Molecule:ll-diaminopimelate aminotransferase;
PDBTitle: l,l-diaminopimelate aminotransferase from chalmydomonas reinhardtii
40d1vdha_



not modelled 20.6 9 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Chlorite dismutase-like
41d1go3e1



not modelled 20.5 12 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
42c3ihjA_



not modelled 20.5 5 PDB header:transferase
Chain: A: PDB Molecule:alanine aminotransferase 2;
PDBTitle: human alanine aminotransferase 2 in complex with plp
43d1eo1a_



not modelled 20.2 15 Fold:Ribonuclease H-like motif
Superfamily:Nitrogenase accessory factor-like
Family:MTH1175-like
44c3cmwA_



not modelled 19.9 19 PDB header:recombination/dna
Chain: A: PDB Molecule:protein reca;
PDBTitle: mechanism of homologous recombination from the reca-2 ssdna/dsdna structures
45c3a2kB_



not modelled 19.9 8 PDB header:ligase/rna
Chain: B: PDB Molecule:trna(ile)-lysidine synthase;
PDBTitle: crystal structure of tils complexed with trna
46c1pt1B_



not modelled 19.8 16 PDB header:lyase
Chain: B: PDB Molecule:aspartate 1-decarboxylase;
PDBTitle: unprocessed pyruvoyl dependent aspartate decarboxylase with histidine2 11 mutated to alanine
47d1ppya_



not modelled 19.8 16 Fold:Double psi beta-barrel
Superfamily:ADC-like
Family:Pyruvoyl dependent aspartate decarboxylase, ADC
48c2wfbA_



not modelled 18.8 16 PDB header:biosynthetic protein
Chain: A: PDB Molecule:putative uncharacterized protein orp;
PDBTitle: high resolution structure of the apo form of the orange2 protein (orp) from desulfovibrio gigas
49d2ay1a_



not modelled 18.1 16 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:AAT-like
50c3pg8B_



not modelled 17.2 11 PDB header:transferase
Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase;
PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima
51d7aata_



not modelled 16.8 11 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:AAT-like
52c3eypB_



not modelled 16.5 24 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative alpha-l-fucosidase;
PDBTitle: crystal structure of putative alpha-l-fucosidase from bacteroides2 thetaiotaomicron
53c3gitA_



not modelled 16.4 32 PDB header:transferase
Chain: A: PDB Molecule:carbon monoxide dehydrogenase/acetyl-coa synthase subunit
PDBTitle: crystal structure of a truncated acetyl-coa synthase
54d1lt7a_



not modelled 16.1 25 Fold:TIM beta/alpha-barrel
Superfamily:Homocysteine S-methyltransferase
Family:Homocysteine S-methyltransferase
55c2nvgA_



not modelled 15.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit;
PDBTitle: soluble domain of rieske iron sulfur protein.
56d3cdda2



not modelled 15.5 15 Fold:Phage tail proteins
Superfamily:Phage tail proteins
Family:Baseplate protein-like
57c2vxhF_



not modelled 15.3 0 PDB header:oxidoreductase
Chain: F: PDB Molecule:chlorite dismutase;
PDBTitle: the crystal structure of chlorite dismutase: a detox enzyme2 producing molecular oxygen
58c3k7yA_



not modelled 14.8 10 PDB header:transferase
Chain: A: PDB Molecule:aspartate aminotransferase;
PDBTitle: aspartate aminotransferase of plasmodium falciparum
59d1x0ma1



not modelled 14.5 17 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:AAT-like
60d1w7la_



not modelled 14.0 12 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:AAT-like
61c2c45F_



not modelled 13.9 11 PDB header:lyase
Chain: F: PDB Molecule:aspartate 1-decarboxylase precursor;
PDBTitle: native precursor of pyruvoyl dependent aspartate2 decarboxylase
62c3c9uB_



not modelled 13.4 13 PDB header:transferase
Chain: B: PDB Molecule:thiamine monophosphate kinase;
PDBTitle: aathil complexed with adp and tpp
63c2ebbA_



not modelled 13.0 15 PDB header:lyase
Chain: A: PDB Molecule:pterin-4-alpha-carbinolamine dehydratase;
PDBTitle: crystal structure of pterin-4-alpha-carbinolamine2 dehydratase (pterin carbinolamine dehydratase) from3 geobacillus kaustophilus hta426
64c3pplB_



not modelled 12.7 14 PDB header:transferase
Chain: B: PDB Molecule:aspartate aminotransferase;
PDBTitle: crystal structure of an aspartate transaminase (ncgl0237, cgl0240)2 from corynebacterium glutamicum atcc 13032 kitasato at 1.25 a3 resolution
65d2r5ea1



not modelled 12.6 12 Fold:PLP-dependent transferase-like
Superfamily:PLP-dependent transferases
Family:AAT-like
66c3nn4C_



not modelled 12.5 5 PDB header:oxidoreductase
Chain: C: PDB Molecule:chlorite dismutase;
PDBTitle: structure of chlorite dismutase from candidatus nitrospira defluvii2 r173k mutant
67c2oxlA_



not modelled 12.3 21 PDB header:gene regulation
Chain: A: PDB Molecule:hypothetical protein ymgb;
PDBTitle: structure and function of the e. coli protein ymgb: a protein critical2 for biofilm formation and acid resistance
68d1l0sa_



not modelled 12.2 21 Fold:Single-stranded left-handed beta-helix
Superfamily:An insect antifreeze protein
Family:An insect antifreeze protein
69c3m84A_



not modelled 12.1 13 PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylformylglycinamidine cyclo-ligase;
PDBTitle: crystal structure of phosphoribosylaminoimidazole synthetase from2 francisella tularensis
70c2jz2A_



not modelled 12.1 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:ssl0352 protein;
PDBTitle: solution nmr structure of ssl0352 protein from synechocystis sp. pcc2 6803. northeast structural genomics consortium target sgr42
71c3muxB_



not modelled 12.0 13 PDB header:lyase
Chain: B: PDB Molecule:putative 4-hydroxy-2-oxoglutarate aldolase;
PDBTitle: the crystal structure of a putative 4-hydroxy-2-oxoglutarate aldolase2 from bacillus anthracis to 1.45a
72d2nu7b2



not modelled 11.9 25 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:Succinyl-CoA synthetase, beta-chain, N-terminal domain
73c3m6yA_



not modelled 11.7 13 PDB header:lyase
Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase;
PDBTitle: structure of 4-hydroxy-2-oxoglutarate aldolase from bacillus cereus at2 1.45 a resolution.
74d1w44a_



not modelled 11.7 24 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
75c1ni5A_



not modelled 11.4 7 PDB header:cell cycle
Chain: A: PDB Molecule:putative cell cycle protein mesj;
PDBTitle: structure of the mesj pp-atpase from escherichia coli
76c2w9mB_



not modelled 11.3 25 PDB header:dna replication
Chain: B: PDB Molecule:polymerase x;
PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans
77c3kxyW_



not modelled 10.7 25 PDB header:chaperone/transcription inhibitor
Chain: W: PDB Molecule:exse;
PDBTitle: crystal structure of the exsc-exse complex
78c3cmuA_



not modelled 10.7 16 PDB header:recombination/dna
Chain: A: PDB Molecule:protein reca;
PDBTitle: mechanism of homologous recombination from the reca-2 ssdna/dsdna structures
79d1m8na_



not modelled 10.3 14 Fold:Single-stranded left-handed beta-helix
Superfamily:An insect antifreeze protein
Family:An insect antifreeze protein
80d2p5zx2



not modelled 10.2 25 Fold:Phage tail proteins
Superfamily:Phage tail proteins
Family:Baseplate protein-like
81d1ru3a_



not modelled 10.1 23 Fold:Prismane protein-like
Superfamily:Prismane protein-like
Family:Acetyl-CoA synthase
82c3eibB_



not modelled 9.8 19 PDB header:transferase
Chain: B: PDB Molecule:ll-diaminopimelate aminotransferase;
PDBTitle: crystal structure of k270n variant of ll-diaminopimelate2 aminotransferase from arabidopsis thaliana
83c2gp4A_



not modelled 9.8 24 PDB header:lyase
Chain: A: PDB Molecule:6-phosphogluconate dehydratase;
PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis
84d1oaoc_



not modelled 9.7 32 Fold:Prismane protein-like
Superfamily:Prismane protein-like
Family:Acetyl-CoA synthase
85c3bzwA_



not modelled 9.6 12 PDB header:hydrolase
Chain: A: PDB Molecule:putative lipase;
PDBTitle: crystal structure of a putative lipase from bacteroides2 thetaiotaomicron
86d3bzwa1



not modelled 9.6 12 Fold:Flavodoxin-like
Superfamily:SGNH hydrolase
Family:BT2961-like
87c3bkdB_



not modelled 9.6 38 PDB header:viral protein, membrane protein
Chain: B: PDB Molecule:transmembrane domain of matrix protein m2;
PDBTitle: high resolution crystal structure of transmembrane domain of m22 protein
88c3bkdG_



not modelled 9.6 38 PDB header:viral protein, membrane protein
Chain: G: PDB Molecule:transmembrane domain of matrix protein m2;
PDBTitle: high resolution crystal structure of transmembrane domain of m22 protein
89c3bkdD_



not modelled 9.6 38 PDB header:viral protein, membrane protein
Chain: D: PDB Molecule:transmembrane domain of matrix protein m2;
PDBTitle: high resolution crystal structure of transmembrane domain of m22 protein
90c3bkdC_



not modelled 9.6 38 PDB header:viral protein, membrane protein
Chain: C: PDB Molecule:transmembrane domain of matrix protein m2;
PDBTitle: high resolution crystal structure of transmembrane domain of m22 protein
91c3bkdE_



not modelled 9.6 38 PDB header:viral protein, membrane protein
Chain: E: PDB Molecule:transmembrane domain of matrix protein m2;
PDBTitle: high resolution crystal structure of transmembrane domain of m22 protein
92c3bkdF_



not modelled 9.6 38 PDB header:viral protein, membrane protein
Chain: F: PDB Molecule:transmembrane domain of matrix protein m2;
PDBTitle: high resolution crystal structure of transmembrane domain of m22 protein
93c3bkdA_



not modelled 9.6 38 PDB header:viral protein, membrane protein
Chain: A: PDB Molecule:transmembrane domain of matrix protein m2;
PDBTitle: high resolution crystal structure of transmembrane domain of m22 protein
94c3bkdH_



not modelled 9.6 38 PDB header:viral protein, membrane protein
Chain: H: PDB Molecule:transmembrane domain of matrix protein m2;
PDBTitle: high resolution crystal structure of transmembrane domain of m22 protein
95d1qlma_



not modelled 9.4 15 Fold:Methenyltetrahydromethanopterin cyclohydrolase
Superfamily:Methenyltetrahydromethanopterin cyclohydrolase
Family:Methenyltetrahydromethanopterin cyclohydrolase
96c2kadC_



not modelled 9.4 38 PDB header:membrane protein
Chain: C: PDB Molecule:transmembrane peptide of matrix protein 2;
PDBTitle: magic-angle-spinning solid-state nmr structure of influenza2 a m2 transmembrane domain
97c2kadA_



not modelled 9.4 38 PDB header:membrane protein
Chain: A: PDB Molecule:transmembrane peptide of matrix protein 2;
PDBTitle: magic-angle-spinning solid-state nmr structure of influenza2 a m2 transmembrane domain
98c2kadB_



not modelled 9.4 38 PDB header:membrane protein
Chain: B: PDB Molecule:transmembrane peptide of matrix protein 2;
PDBTitle: magic-angle-spinning solid-state nmr structure of influenza2 a m2 transmembrane domain
99c2kadD_



not modelled 9.4 38 PDB header:membrane protein
Chain: D: PDB Molecule:transmembrane peptide of matrix protein 2;
PDBTitle: magic-angle-spinning solid-state nmr structure of influenza2 a m2 transmembrane domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0