Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	Q	S	T	I	A	L	A	L	L	P	L	L	F	T	P	V	T	K	A	R	T	P	E	M	P	V	L	E	N	R	A	A	Q	G	D	I	T	A	P	G	G	A	R	R	L	T	G	D	Q	T	A	A	L	R	D	S	L	S
Secondary structure
SS confidence
Disorder		?	?	?	?											?	?	?	?	?	?	?	?	?	?	?	?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?	?	?				?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	K	P	A	K	N	I	I	L	L	I	G	D	G	M	G	D	S	E	I	T	A	A	R	N	Y	A	E	G	A	G	G	F	F	K	G	I	D	A	L	P	L	T	G	Q	Y	T	H	Y	A	L	N	K	K	T	G	K	P	D	Y
Secondary structure
SS confidence
Disorder		?																												?	?	?	?	?	?	?																		?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	T	D	S	A	A	S	A	T	A	W	S	T	G	V	K	T	Y	N	G	A	L	G	V	D	I	H	E	K	D	H	P	T	I	L	E	M	A	K	A	A	G	L	A	T	G	N	V	S	T	A	E	L	Q	D	A	T	P	A	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	V	A	H	V	T	S	R	K	C	Y	G	P	S	A	T	S	E	K	C	P	G	N	A	L	E	K	G	G	K	G	S	I	T	E	Q	L	L	N	A	R	A	D	V	T	L	G	G	G	A	K	T	F	A	E	T	A	T	A	G
Secondary structure
SS confidence
Disorder													?		?		?	?	?	?	?	?	?																																			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	W	Q	G	K	T	L	R	E	Q	A	Q	A	R	G	Y	Q	L	V	S	D	A	A	S	L	N	S	V	T	E	A	N	Q	Q	K	P	L	L	G	L	F	A	D	G	N	M	P	V	R	W	L	G	P	K	A	T	Y	H	G	N
Secondary structure
SS confidence
Disorder			?																										?				?	?																				?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		I	D	K	P	A	V	T	C	T	P	N	P	Q	R	N	D	S	V	P	T	L	A	Q	M	T	D	K	A	I	E	L	L	S	K	N	E	K	G	F	F	L	Q	V	E	G	A	S	I	D	K	Q	D	H	A	A	N	P	C	G	Q
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?	?	?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		I	G	E	T	V	D	L	D	E	A	V	Q	R	A	L	E	F	A	K	K	E	G	N	T	L	V	I	V	T	A	D	H	A	H	A	S	Q	I	V	A	P	D	T	K	A	P	G	L	T	Q	A	L	N	T	K	D	G	A	V	M
Secondary structure
SS confidence
Disorder																																								?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
Sequence		V	M	S	Y	G	N	S	E	E	D	S	Q	E	H	T	G	S	Q	L	R	I	A	A	Y	G	P	H	A	A	N	V	V	G	L	T	D	Q	T	D	L	F	Y	T	M	K	A	A	L	G	L	K
Secondary structure
SS confidence
Disorder								?	?	?		?	?	?	?																																			?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1y6v chain A domain 1 Region: 23 - 471 Aligned: 449 Modelled: 449 Confidence: 100.0% Identity: 100% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Alkaline phosphatase Phyre2 PDB 1k7h chain A Region: 49 - 470 Aligned: 389 Modelled: 395 Confidence: 100.0% Identity: 34% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Alkaline phosphatase Phyre2 PDB 1zed chain A domain 1 Region: 53 - 471 Aligned: 386 Modelled: 387 Confidence: 100.0% Identity: 34% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Alkaline phosphatase Phyre2 PDB 1ew2 chain A Region: 53 - 471 Aligned: 386 Modelled: 392 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase Phyre2 PDB 2x98 chain A Region: 61 - 471 Aligned: 361 Modelled: 370 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase Phyre2 PDB 2w0y chain B Region: 61 - 471 Aligned: 361 Modelled: 374 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase Phyre2 PDB 3e2d chain B Region: 62 - 468 Aligned: 363 Modelled: 367 Confidence: 100.0% Identity: 34% PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase Phyre2 PDB 3a52 chain A Region: 66 - 469 Aligned: 343 Modelled: 362 Confidence: 100.0% Identity: 37% PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. Phyre2 PDB 2iuc chain B Region: 62 - 470 Aligned: 337 Modelled: 357 Confidence: 100.0% Identity: 31% PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 Phyre2 PDB 3m8y chain C Region: 63 - 471 Aligned: 313 Modelled: 313 Confidence: 99.9% Identity: 20% PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation Phyre2 PDB 2i09 chain A Region: 62 - 471 Aligned: 334 Modelled: 341 Confidence: 99.9% Identity: 17% PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans Phyre2 PDB 3igz chain B Region: 284 - 471 Aligned: 173 Modelled: 175 Confidence: 99.7% Identity: 19% PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration Phyre2 PDB 1o98 chain A domain 2 Region: 65 - 471 Aligned: 261 Modelled: 267 Confidence: 99.6% Identity: 22% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain Phyre2 PDB 1o98 chain A Region: 285 - 471 Aligned: 159 Modelled: 162 Confidence: 99.6% Identity: 19% PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate Phyre2 PDB 1hdh chain A Region: 62 - 471 Aligned: 308 Modelled: 322 Confidence: 99.5% Identity: 19% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3ed4 chain A Region: 66 - 471 Aligned: 301 Modelled: 305 Confidence: 99.5% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli Phyre2 PDB 1auk chain A Region: 63 - 471 Aligned: 307 Modelled: 307 Confidence: 99.4% Identity: 19% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3q3q chain A Region: 56 - 471 Aligned: 340 Modelled: 343 Confidence: 99.4% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 Phyre2 PDB 2zkt chain B Region: 65 - 470 Aligned: 307 Modelled: 317 Confidence: 99.4% Identity: 19% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii Phyre2 PDB 3lxq chain B Region: 61 - 471 Aligned: 260 Modelled: 276 Confidence: 99.4% Identity: 22% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a Phyre2 1 d1y6va1 2 d1k7ha_ 3 d1zeda1 4 c1ew2A_ 5 c2x98A_ 6 c2w0yB_ 7 c3e2dB_ 8 c3a52A_ 9 c2iucB_ 10 c3m8yC_ 11 c2i09A_ 12 c3igzB_ 13 d1o98a2 14 c1o98A_ 15 d1hdha_ 16 c3ed4A_ 17 d1auka_ 18 c3q3qA_ 19 c2zktB_ 20 c3lxqB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1y6va1 100.0 100 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 2 d1k7ha_ 100.0 34 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 3 d1zeda1 100.0 34 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 4 c1ew2A_ 100.0 34 PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase 5 c2x98A_ 100.0 34 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 6 c2w0yB_ 100.0 34 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 7 c3e2dB_ 100.0 34 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase 8 c3a52A_ 100.0 37 PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. 9 c2iucB_ 100.0 31 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 10 c3m8yC_ 99.9 20 PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation 11 c2i09A_ 99.9 17 PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans 12 c3igzB_ 99.7 19 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 13 d1o98a2 99.6 22 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain 14 c1o98A_ 99.6 19 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 15 d1hdha_ 99.5 19 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 16 c3ed4A_ 99.5 19 PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli 17 d1auka_ 99.4 19 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 18 c3q3qA_ 99.4 21 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 19 c2zktB_ 99.4 19 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii 20 c3lxqB_ 99.4 22 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a 21 d2i09a1 not modelled 99.3 18 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:DeoB catalytic domain-like 22 d1p49a_ not modelled 99.3 15 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 23 d1fsua_ not modelled 99.3 21 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 24 c2vqrA_ not modelled 99.2 15 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily 25 c2w8dB_ not modelled 99.2 13 PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis 26 c2qzuA_ not modelled 99.2 15 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 27 c2w5tA_ not modelled 99.2 14 PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. 28 c2xrgA_ not modelled 99.1 25 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 29 c2xr9A_ not modelled 99.1 24 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 30 c3b5qB_ not modelled 99.0 21 PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution 31 c3szzA_ not modelled 98.4 18 PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate 32 d1ei6a_ not modelled 98.4 24 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Phosphonoacetate hydrolase 33 c2gsoB_ not modelled 98.2 22 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate 34 c2d1gB_ not modelled 96.8 16 PDB header:hydrolase Chain: B: PDB Molecule:acid phosphatase; PDBTitle: structure of francisella tularensis acid phosphatase a (acpa) bound to2 orthovanadate 35 c3iddA_ not modelled 79.0 27 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 36 d1b4ub_ not modelled 76.8 23 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 37 c1q14A_ not modelled 47.4 14 PDB header:hydrolase Chain: A: PDB Molecule:hst2 protein; PDBTitle: structure and autoregulation of the yeast hst2 homolog of sir2 38 c1h2aS_ not modelled 40.0 39 PDB header:oxidoreductase Chain: S: PDB Molecule:hydrogenase; PDBTitle: single crystals of hydrogenase from desulfovibrio vulgaris 39 d1wuis1 not modelled 40.0 39 Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nickel-iron hydrogenase, small subunit 40 d1j8fa_ not modelled 39.5 21 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 41 d2ihta3 not modelled 35.0 16 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 42 d1frfs_ not modelled 31.8 25 Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nickel-iron hydrogenase, small subunit 43 d1j83a_ not modelled 30.9 20 Fold:Galactose-binding domain-like Superfamily:Galactose-binding domain-like Family:Family 17 carbohydrate binding module, CBM17 44 c3glsC_ not modelled 28.9 8 PDB header:hydrolase Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3, PDBTitle: crystal structure of human sirt3 45 d1q1aa_ not modelled 26.3 18 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 46 c2q1wC_ not modelled 24.6 13 PDB header:sugar binding protein Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase; PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+ 47 c3euaD_ not modelled 23.8 10 PDB header:isomerase Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase; PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution 48 c2pjuD_ not modelled 21.7 18 PDB header:transcription Chain: D: PDB Molecule:propionate catabolism operon regulatory protein; PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr 49 d1e3da_ not modelled 21.2 29 Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nickel-iron hydrogenase, small subunit 50 d2a84a1 not modelled 19.7 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 51 c3bq9A_ not modelled 19.5 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted rossmann fold nucleotide-binding domain- PDBTitle: crystal structure of predicted nucleotide-binding protein from2 idiomarina baltica os145 52 c3t9qB_ not modelled 17.7 25 PDB header:hydrolase Chain: B: PDB Molecule:stage ii sporulation protein e; PDBTitle: structure of the phosphatase domain of the cell fate determinant2 spoiie from bacillus subtilis (mn presoaked) 53 d2pjua1 not modelled 17.0 18 Fold:Chelatase-like Superfamily:PrpR receptor domain-like Family:PrpR receptor domain-like 54 c3cdiA_ not modelled 15.8 21 PDB header:transferase Chain: A: PDB Molecule:polynucleotide phosphorylase; PDBTitle: crystal structure of e. coli pnpase 55 c3absD_ not modelled 15.0 30 PDB header:lyase Chain: D: PDB Molecule:ethanolamine ammonia-lyase light chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with adeninylpentylcobalamin and ethanolamine 56 c3anyB_ not modelled 15.0 30 PDB header:lyase Chain: B: PDB Molecule:ethanolamine ammonia-lyase light chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with cn-cbl and (r)-2-amino-1-propanol 57 c3pu9A_ not modelled 14.9 25 PDB header:transferase Chain: A: PDB Molecule:protein serine/threonine phosphatase; PDBTitle: crystal structure of serine/threonine phosphatase sphaerobacter2 thermophilus dsm 20745 58 d1w0da_ not modelled 14.8 25 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 59 c3fkjA_ not modelled 14.8 9 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerases; PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution 60 c3b3jA_ not modelled 13.9 31 PDB header:transferase Chain: A: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: the 2.55 a crystal structure of the apo catalytic domain of2 coactivator-associated arginine methyl transferase i(carm1:28-507,3 residues 28-146 and 479-507 not ordered) 61 c3u1hA_ not modelled 13.9 45 PDB header:oxidoreductase Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase; PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus 62 d2d0oa2 not modelled 13.7 29 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:ATPase domain of dehydratase reactivase alpha subunit 63 c2pr7A_ not modelled 13.4 27 PDB header:hydrolase Chain: A: PDB Molecule:haloacid dehalogenase/epoxide hydrolase family; PDBTitle: crystal structure of uncharacterized protein (np_599989.1) from2 corynebacterium glutamicum atcc 13032 kitasato at 1.44 a resolution 64 c1okjB_ not modelled 13.2 14 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protease yeaz; PDBTitle: crystal structure of the essential e. coli yeaz2 protein by mad method using the gadolinium complex3 "dotma" 65 c2q5cA_ not modelled 12.6 11 PDB header:transcription Chain: A: PDB Molecule:ntrc family transcriptional regulator; PDBTitle: crystal structure of ntrc family transcriptional regulator from2 clostridium acetobutylicum 66 d1qh8a_ not modelled 12.4 6 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 67 d1u7pa_ not modelled 12.1 18 Fold:HAD-like Superfamily:HAD-like Family:Magnesium-dependent phosphatase-1, Mdp1 68 d1uhma_ not modelled 12.0 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Linker histone H1/H5 69 d1ybha3 not modelled 12.0 26 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 70 c2x48B_ not modelled 11.9 15 PDB header:viral protein Chain: B: PDB Molecule:cag38821; PDBTitle: orf 55 from sulfolobus islandicus rudivirus 1 71 c2i56A_ not modelled 11.8 15 PDB header:isomerase, metal-binding protein Chain: A: PDB Molecule:l-rhamnose isomerase; PDBTitle: crystal structure of l-rhamnose isomerase from pseudomonas2 stutzeri with l-rhamnose 72 d1pvda3 not modelled 11.3 43 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 73 c3rgwS_ not modelled 11.0 29 PDB header:oxidoreductase/oxidoreductase Chain: S: PDB Molecule:membrane-bound hydrogenase (nife) small subunit hoxk; PDBTitle: crystal structure at 1.5 a resolution of an h2-reduced, o2-tolerant2 hydrogenase from ralstonia eutropha unmasks a novel iron-sulfur3 cluster 74 d2fhza1 not modelled 10.9 23 Fold:ImmE5-like Superfamily:ImmE5-like Family:ImmE5-like 75 c3bz6A_ not modelled 10.9 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0502 protein pspto_2686; PDBTitle: crystal structure of a conserved protein of unknown function from2 pseudomonas syringae pv. tomato str. dc3000 76 d1ek6a_ not modelled 10.8 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 77 c3blxL_ not modelled 10.7 18 PDB header:oxidoreductase Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2; PDBTitle: yeast isocitrate dehydrogenase (apo form) 78 d1cc1s_ not modelled 10.6 38 Fold:HydA/Nqo6-like Superfamily:HydA/Nqo6-like Family:Nickel-iron hydrogenase, small subunit 79 c2kjwA_ not modelled 10.5 38 PDB header:ribosomal protein Chain: A: PDB Molecule:30s ribosomal protein s6; PDBTitle: solution structure and backbone dynamics of the permutant2 p54-55 80 c3cdjA_ not modelled 10.4 21 PDB header:transferase Chain: A: PDB Molecule:polynucleotide phosphorylase; PDBTitle: crystal structure of the e. coli kh/s1 domain truncated2 pnpase 81 d1g6q1_ not modelled 10.2 29 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 82 d1e3ha5 not modelled 10.2 10 Fold:Ribonuclease PH domain 2-like Superfamily:Ribonuclease PH domain 2-like Family:Ribonuclease PH domain 2-like 83 c3enkB_ not modelled 10.2 25 PDB header:isomerase Chain: B: PDB Molecule:udp-glucose 4-epimerase; PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei 84 d1xlma_ not modelled 10.0 14 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 85 c3gxxB_ not modelled 10.0 25 PDB header:transcription Chain: B: PDB Molecule:transcription elongation factor spt6; PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b 86 c2dfxI_ not modelled 9.9 23 PDB header:hydrolase Chain: I: PDB Molecule:colicin-e5 immunity protein; PDBTitle: crystal structure of the carboxy terminal domain of colicin2 e5 complexed with its inhibitor 87 c1t9dB_ not modelled 9.9 31 PDB header:transferase Chain: B: PDB Molecule:acetolactate synthase, mitochondrial; PDBTitle: crystal structure of yeast acetohydroxyacid synthase in2 complex with a sulfonylurea herbicide, metsulfuron methyl 88 c3es2A_ not modelled 9.2 17 PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: structure of the c-terminal phosphatase domain of p.2 aeruginonsa rssb 89 d1ghca_ not modelled 9.2 32 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Linker histone H1/H5 90 d1tfra2 not modelled 9.1 18 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 91 d1p4da_ not modelled 9.0 23 Fold:Origin of replication-binding domain, RBD-like Superfamily:Origin of replication-binding domain, RBD-like Family:Relaxase domain 92 d1a05a_ not modelled 8.9 45 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 93 d1lxna_ not modelled 8.9 24 Fold:Ferredoxin-like Superfamily:MTH1187/YkoF-like Family:MTH1187-like 94 d1t9ba3 not modelled 8.9 38 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 95 d2blna1 not modelled 8.9 5 Fold:FMT C-terminal domain-like Superfamily:FMT C-terminal domain-like Family:Post formyltransferase domain 96 c1zorB_ not modelled 8.7 26 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile thermotoga maritima 97 d1qyia_ not modelled 8.6 23 Fold:HAD-like Superfamily:HAD-like Family:Hypothetical protein MW1667 (SA1546) 98 c3ir9A_ not modelled 8.6 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:peptide chain release factor subunit 1; PDBTitle: c-terminal domain of peptide chain release factor from2 methanosarcina mazei. 99 c3r6mD_ not modelled 8.5 13 PDB header:hydrolase Chain: D: PDB Molecule:yeaz, resuscitation promoting factor; PDBTitle: crystal structure of vibrio parahaemolyticus yeaz

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0